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The map label for this gene is sbm [H]

Identifier: 108800789

GI number: 108800789

Start: 4070924

End: 4071322

Strand: Reverse

Name: sbm [H]

Synonym: Mmcs_3825

Alternate gene names: 108800789

Gene position: 4071322-4070924 (Counterclockwise)

Preceding gene: 108800790

Following gene: 108800788

Centisome position: 71.36

GC content: 70.18

Gene sequence:

>399_bases
ATGCCGACTCGTGTTCTCGTCGCCAAACCCGGCCTGGACGGCCATGACCGAGGCGCCAAGATCGTCGCGCGCACCCTGCG
CGACGCCGGCTTCGAGGTCATCTACACCGGTATCCGTCAGCGCATCGAGGACATCGTGTCGATCGCGCTGCAGGAGGACG
TCGCGGTGGTCGGGCTCTCGATCCTCTCCGGAGCCCACCTGGCCCTGACCCGGCGGACGGTCGACGCGCTGCGCGCGGCC
GACGCCGGCGACATCGCCGTCGTGGTCGGCGGCACCATCCCGCAGGCCGACGTGCCGAAACTGCTCGAAGCCGGTGCGGC
CGCGGTCTTCCCGACCGGCACACCGTTGGAGACGCTGGTCACCGAGGTGCGCAAGCTGACCGGTGAGGTTGCCCAGTGA

Upstream 100 bases:

>100_bases
GCGAAGGCGTACTGCACCGTCGGCGAGATGGTCTCGGCGCTCAAAGCGGTGTGGGGCGAATTCCAGCAGCCTGTCGTCTT
TTAGAAGGGGGGTGTTCTAG

Downstream 100 bases:

>100_bases
CGGTTCTGTCGCCGAACGTGCGCCTAGCGCGACTTTTCGGCCGATTTTTCGCATTGACCGCACGTTCGCCGGAGGAGTAC
CGATGAGACTCGGTGTGATG

Product: methylmalonyl-CoA mutase C-terminal domain-containing protein

Products: succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MPTRVLVAKPGLDGHDRGAKIVARTLRDAGFEVIYTGIRQRIEDIVSIALQEDVAVVGLSILSGAHLALTRRTVDALRAA
DAGDIAVVVGGTIPQADVPKLLEAGAAAVFPTGTPLETLVTEVRKLTGEVAQ

Sequences:

>Translated_132_residues
MPTRVLVAKPGLDGHDRGAKIVARTLRDAGFEVIYTGIRQRIEDIVSIALQEDVAVVGLSILSGAHLALTRRTVDALRAA
DAGDIAVVVGGTIPQADVPKLLEAGAAAVFPTGTPLETLVTEVRKLTGEVAQ
>Mature_131_residues
PTRVLVAKPGLDGHDRGAKIVARTLRDAGFEVIYTGIRQRIEDIVSIALQEDVAVVGLSILSGAHLALTRRTVDALRAAD
AGDIAVVVGGTIPQADVPKLLEAGAAAVFPTGTPLETLVTEVRKLTGEVAQ

Specific function: Unknown

COG id: COG2185

COG function: function code I; Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 B12-binding domain [H]

Homologues:

Organism=Homo sapiens, GI156105689, Length=111, Percent_Identity=40.5405405405405, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1789284, Length=126, Percent_Identity=42.0634920634921, Blast_Score=94, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI25144500, Length=120, Percent_Identity=40, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006159
- InterPro:   IPR016176
- InterPro:   IPR014348
- InterPro:   IPR006158
- InterPro:   IPR006099
- InterPro:   IPR006098 [H]

Pfam domain/function: PF02310 B12-binding; PF01642 MM_CoA_mutase [H]

EC number: NA

Molecular weight: Translated: 13744; Mature: 13613

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTRVLVAKPGLDGHDRGAKIVARTLRDAGFEVIYTGIRQRIEDIVSIALQEDVAVVGLS
CCCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSGAHLALTRRTVDALRAADAGDIAVVVGGTIPQADVPKLLEAGAAAVFPTGTPLETLV
HHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHCCCCEECCCCCCHHHHH
TEVRKLTGEVAQ
HHHHHHHHHCCC
>Mature Secondary Structure 
PTRVLVAKPGLDGHDRGAKIVARTLRDAGFEVIYTGIRQRIEDIVSIALQEDVAVVGLS
CCEEEEECCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSGAHLALTRRTVDALRAADAGDIAVVVGGTIPQADVPKLLEAGAAAVFPTGTPLETLV
HHCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHCCCCEECCCCCCHHHHH
TEVRKLTGEVAQ
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Co [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-methylmalonyl-CoA [C]

Specific reaction: L-methylmalonyl-CoA = succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1355087; 9278503 [H]