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The map label for this gene is ysgA [C]

Identifier: 108800601

GI number: 108800601

Start: 3879406

End: 3881364

Strand: Reverse

Name: ysgA [C]

Synonym: Mmcs_3635

Alternate gene names: 108800601

Gene position: 3881364-3879406 (Counterclockwise)

Preceding gene: 108800603

Following gene: 108800600

Centisome position: 68.03

GC content: 68.56

Gene sequence:

>1959_bases
GTGATTGCAGACGCGGATACCGTCAGGGGTGGCCGGTCGGTCGCGAGGACGAGGACCACGAAGAGTGAGGAGAACCAGCG
CGTGAGACGCCAGGTGCGGGCGAACTACGGTGCGTCGCTGTCGCCTGACGCGACGGCCTTCGCGCACCTCGTCGACGACG
GCGGCTTCCCCCGGGCGGTGCAGCGGTTCCTGCTGGGCTGGCGGGCGAGTTCCTCACGAGACGTGGAGTTGCCGGTCGAG
GGCCCGGTCACCCGGGTCATGCATTCCGCCGACGGGCACTGGCTGGCCTGCCAGGTCGCCCCCGACGGCAGTGACCGGTT
CCAGATCTGGGTCGTGACAACCGATCCCGATGACCGGGACGCCCGCCGCATCGACTCGTGGCCCATGGATCAGCCGGACG
GCAGCGCCGAACTCATCGGTTGGGACGGCACCCAGGTCGCGGCGATCCTCACCGGTGAGGACGGTGTCGGCAGTTCGTGT
CTGATCGACCCGGCCGACGGCGCGACCATCGTGCTGGACCGCCGGACGGCCGGACGCCTGGTCGACGCCTGGGCCGGCGC
GGCGCTGGTGCGGGTGGGCCCACGCGGCTACCGCGATCTCATCATGCTGCGCGGGCTCACCGAAACCGCGCTGCTGCCCT
ACGATCCGGGTTCGACCACCGACCTGGGGTTCATCCTCGACGACCACAGCCCACGGCGCCTGCGGTCGGGCCCGATGGGG
GAGAGTTTCACGCTCTACCACCCGGCCAAGGACTACGGGCTCAACAGCACCGAGGGGTACGTGCGGGCGTTGATCCGCAG
CGACAACGGCGGATCTCACGCGCGCCTCATCGAGGTGACCACCACCGCCGAGGGCGTCTCCTACCACGTCGTCGCGGAGA
AGCCGGGCTTCGACCTCGACGAGTTCGTCGTCAGCGACGATATGTCGACCGTCGCGCTCCTGTGGAATGTCAACGGCTGC
AGTGAATTACAGATCCTCGAATACGCGGACAACACGTTGTCCGAACCCATCCCGCTGCCCGGTCTCGTCGCGACGGAACT
GACGATCAGCGCGGGCGGTTCGATGGTCGCGATGACGGTGGAGAGCCCGTCGCTGCCGCCCACCGTCGAACTGGTCGATC
CGCGCTCACGCGAGTGGCAGCGGGTGGACCGCGAACCCAGTGAGGGCCCGCTGACGGCGGATCCCACGCTGGAGGTGGTC
GTCGCCCGTGACGGGATGGAGTTGACCGGTTGGCTGTACCGCCCGCCGGCACCGGTCGAACCCGTCGGCGCGATGATCTT
CCTGCACGGCGGGCCGGAGGGTCAGTCCCGGCCCGGCTACAACGAGTACTACCCGGCTCTGCTGGCCGCGGGCATCACCG
TGTTCACCCCGAACGTGCGCGGCTCGGGCGGCTTCGGCCGTGCGTTCATGCACGCCGACGACAAGGAGCTGCGGTTCGCC
GCGATCGACGACGTGGCCGACTGTGTGCGCTATCTGATCGAGCACGAAGCCGTGCCGGCCGACCGCGTCGCCTGCTGCGG
CTGGTCGTACGGCGGTTATCTGACGCAGGCGGCGTTGACCTTTCACCCGGAGTTGTTCGCCGCCGGCATCAGCATCTGTG
GGATGAGTGATCTGAACACCTGGTATCGCAACACCGAGCCGTGGATCGCGGCGGCCGCCTACCCGAAGTACGGGCACCCG
ATCGGCGACCGCGACCTTCTCGAGCGGCTCTCACCGCTGCTGCGCGCCCCCGCGCTGACCGCCCCGCTGCTGCTGGTGCA
CGGCGGGAACGACACCAACGTGCCACCCAGCGAATCGCAGCAAATGTTCGACGCATTGCGCGCTTTGGACCGCACCGTCG
AGCTGTTGGTGTTCGACGACGACGGTCACGAGATCGTCAAGCGGGAGAACCGGGCCGCGCTCGTCAACGCGATGACGACG
TGGCTGCTCAAGGCGTTCTCGGCGGCTTCGGTGCTCTGA

Upstream 100 bases:

>100_bases
CGGCTCGGCGCCGTCACGACGTGGTGACTCGGTCATACCCACCTCATGGTCGCAGGGTACCTGCGGATCCCGTCGCGCCG
TCACGGTGTTGGGTGTGCCG

Downstream 100 bases:

>100_bases
CGATCATCCGCCCCGGACAACAGGTTTGGACAAATTGTCCTGGGGGTAAACGGTGTTGCGCGCCACTCCGGCGCGAACAG
GATGGAGGCTGGGGCATGAG

Product: peptidase S9, prolyl oligopeptidase active site region

Products: NA

Alternate protein names: AARE; Acyl-peptide hydrolase; APH; Acylaminoacyl-peptidase [H]

Number of amino acids: Translated: 652; Mature: 652

Protein sequence:

>652_residues
MIADADTVRGGRSVARTRTTKSEENQRVRRQVRANYGASLSPDATAFAHLVDDGGFPRAVQRFLLGWRASSSRDVELPVE
GPVTRVMHSADGHWLACQVAPDGSDRFQIWVVTTDPDDRDARRIDSWPMDQPDGSAELIGWDGTQVAAILTGEDGVGSSC
LIDPADGATIVLDRRTAGRLVDAWAGAALVRVGPRGYRDLIMLRGLTETALLPYDPGSTTDLGFILDDHSPRRLRSGPMG
ESFTLYHPAKDYGLNSTEGYVRALIRSDNGGSHARLIEVTTTAEGVSYHVVAEKPGFDLDEFVVSDDMSTVALLWNVNGC
SELQILEYADNTLSEPIPLPGLVATELTISAGGSMVAMTVESPSLPPTVELVDPRSREWQRVDREPSEGPLTADPTLEVV
VARDGMELTGWLYRPPAPVEPVGAMIFLHGGPEGQSRPGYNEYYPALLAAGITVFTPNVRGSGGFGRAFMHADDKELRFA
AIDDVADCVRYLIEHEAVPADRVACCGWSYGGYLTQAALTFHPELFAAGISICGMSDLNTWYRNTEPWIAAAAYPKYGHP
IGDRDLLERLSPLLRAPALTAPLLLVHGGNDTNVPPSESQQMFDALRALDRTVELLVFDDDGHEIVKRENRAALVNAMTT
WLLKAFSAASVL

Sequences:

>Translated_652_residues
MIADADTVRGGRSVARTRTTKSEENQRVRRQVRANYGASLSPDATAFAHLVDDGGFPRAVQRFLLGWRASSSRDVELPVE
GPVTRVMHSADGHWLACQVAPDGSDRFQIWVVTTDPDDRDARRIDSWPMDQPDGSAELIGWDGTQVAAILTGEDGVGSSC
LIDPADGATIVLDRRTAGRLVDAWAGAALVRVGPRGYRDLIMLRGLTETALLPYDPGSTTDLGFILDDHSPRRLRSGPMG
ESFTLYHPAKDYGLNSTEGYVRALIRSDNGGSHARLIEVTTTAEGVSYHVVAEKPGFDLDEFVVSDDMSTVALLWNVNGC
SELQILEYADNTLSEPIPLPGLVATELTISAGGSMVAMTVESPSLPPTVELVDPRSREWQRVDREPSEGPLTADPTLEVV
VARDGMELTGWLYRPPAPVEPVGAMIFLHGGPEGQSRPGYNEYYPALLAAGITVFTPNVRGSGGFGRAFMHADDKELRFA
AIDDVADCVRYLIEHEAVPADRVACCGWSYGGYLTQAALTFHPELFAAGISICGMSDLNTWYRNTEPWIAAAAYPKYGHP
IGDRDLLERLSPLLRAPALTAPLLLVHGGNDTNVPPSESQQMFDALRALDRTVELLVFDDDGHEIVKRENRAALVNAMTT
WLLKAFSAASVL
>Mature_652_residues
MIADADTVRGGRSVARTRTTKSEENQRVRRQVRANYGASLSPDATAFAHLVDDGGFPRAVQRFLLGWRASSSRDVELPVE
GPVTRVMHSADGHWLACQVAPDGSDRFQIWVVTTDPDDRDARRIDSWPMDQPDGSAELIGWDGTQVAAILTGEDGVGSSC
LIDPADGATIVLDRRTAGRLVDAWAGAALVRVGPRGYRDLIMLRGLTETALLPYDPGSTTDLGFILDDHSPRRLRSGPMG
ESFTLYHPAKDYGLNSTEGYVRALIRSDNGGSHARLIEVTTTAEGVSYHVVAEKPGFDLDEFVVSDDMSTVALLWNVNGC
SELQILEYADNTLSEPIPLPGLVATELTISAGGSMVAMTVESPSLPPTVELVDPRSREWQRVDREPSEGPLTADPTLEVV
VARDGMELTGWLYRPPAPVEPVGAMIFLHGGPEGQSRPGYNEYYPALLAAGITVFTPNVRGSGGFGRAFMHADDKELRFA
AIDDVADCVRYLIEHEAVPADRVACCGWSYGGYLTQAALTFHPELFAAGISICGMSDLNTWYRNTEPWIAAAAYPKYGHP
IGDRDLLERLSPLLRAPALTAPLLLVHGGNDTNVPPSESQQMFDALRALDRTVELLVFDDDGHEIVKRENRAALVNAMTT
WLLKAFSAASVL

Specific function: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N- acetylated amino acid and a peptide with a free N-terminus [H]

COG id: COG1506

COG function: function code E; Dipeptidyl aminopeptidases/acylaminoacyl-peptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S9C family [H]

Homologues:

Organism=Homo sapiens, GI23510451, Length=338, Percent_Identity=23.3727810650888, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25144537, Length=273, Percent_Identity=29.3040293040293, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144540, Length=273, Percent_Identity=29.3040293040293, Blast_Score=113, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17552908, Length=313, Percent_Identity=26.8370607028754, Blast_Score=103, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI25144543, Length=169, Percent_Identity=30.1775147928994, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042
- InterPro:   IPR001375
- InterPro:   IPR004106 [H]

Pfam domain/function: PF00326 Peptidase_S9 [H]

EC number: =3.4.19.1 [H]

Molecular weight: Translated: 70780; Mature: 70780

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIADADTVRGGRSVARTRTTKSEENQRVRRQVRANYGASLSPDATAFAHLVDDGGFPRAV
CCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHH
QRFLLGWRASSSRDVELPVEGPVTRVMHSADGHWLACQVAPDGSDRFQIWVVTTDPDDRD
HHHHHHCCCCCCCCEEECCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCCH
ARRIDSWPMDQPDGSAELIGWDGTQVAAILTGEDGVGSSCLIDPADGATIVLDRRTAGRL
HHHCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCH
VDAWAGAALVRVGPRGYRDLIMLRGLTETALLPYDPGSTTDLGFILDDHSPRRLRSGPMG
HHHHCCCEEEEECCCCHHHHHHHCCCCHHEEEECCCCCCCEEEEEECCCCCHHHHCCCCC
ESFTLYHPAKDYGLNSTEGYVRALIRSDNGGSHARLIEVTTTAEGVSYHVVAEKPGFDLD
CCEEEECCHHHCCCCCCCHHEEEEEECCCCCCEEEEEEEEECCCCCEEEEEECCCCCCHH
EFVVSDDMSTVALLWNVNGCSELQILEYADNTLSEPIPLPGLVATELTISAGGSMVAMTV
HHHCCCCCCEEEEEEECCCCCCEEEEECCCCHHCCCCCCCCEEEEEEEEECCCCEEEEEE
ESPSLPPTVELVDPRSREWQRVDREPSEGPLTADPTLEVVVARDGMELTGWLYRPPAPVE
CCCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC
PVGAMIFLHGGPEGQSRPGYNEYYPALLAAGITVFTPNVRGSGGFGRAFMHADDKELRFA
CCCEEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCEEEECCCCCCEEEE
AIDDVADCVRYLIEHEAVPADRVACCGWSYGGYLTQAALTFHPELFAAGISICGMSDLNT
EHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHEECHHHHHCCHHHCCCHHHHH
WYRNTEPWIAAAAYPKYGHPIGDRDLLERLSPLLRAPALTAPLLLVHGGNDTNVPPSESQ
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHH
QMFDALRALDRTVELLVFDDDGHEIVKRENRAALVNAMTTWLLKAFSAASVL
HHHHHHHHHCCEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIADADTVRGGRSVARTRTTKSEENQRVRRQVRANYGASLSPDATAFAHLVDDGGFPRAV
CCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCHHHH
QRFLLGWRASSSRDVELPVEGPVTRVMHSADGHWLACQVAPDGSDRFQIWVVTTDPDDRD
HHHHHHCCCCCCCCEEECCCCCHHHHHCCCCCCEEEEEECCCCCCEEEEEEEECCCCCCH
ARRIDSWPMDQPDGSAELIGWDGTQVAAILTGEDGVGSSCLIDPADGATIVLDRRTAGRL
HHHCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCEEEECCCCCEEEEECCCCCCH
VDAWAGAALVRVGPRGYRDLIMLRGLTETALLPYDPGSTTDLGFILDDHSPRRLRSGPMG
HHHHCCCEEEEECCCCHHHHHHHCCCCHHEEEECCCCCCCEEEEEECCCCCHHHHCCCCC
ESFTLYHPAKDYGLNSTEGYVRALIRSDNGGSHARLIEVTTTAEGVSYHVVAEKPGFDLD
CCEEEECCHHHCCCCCCCHHEEEEEECCCCCCEEEEEEEEECCCCCEEEEEECCCCCCHH
EFVVSDDMSTVALLWNVNGCSELQILEYADNTLSEPIPLPGLVATELTISAGGSMVAMTV
HHHCCCCCCEEEEEEECCCCCCEEEEECCCCHHCCCCCCCCEEEEEEEEECCCCEEEEEE
ESPSLPPTVELVDPRSREWQRVDREPSEGPLTADPTLEVVVARDGMELTGWLYRPPAPVE
CCCCCCCEEEEECCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCC
PVGAMIFLHGGPEGQSRPGYNEYYPALLAAGITVFTPNVRGSGGFGRAFMHADDKELRFA
CCCEEEEEECCCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCEEEECCCCCCEEEE
AIDDVADCVRYLIEHEAVPADRVACCGWSYGGYLTQAALTFHPELFAAGISICGMSDLNT
EHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHEECHHHHHCCHHHCCCHHHHH
WYRNTEPWIAAAAYPKYGHPIGDRDLLERLSPLLRAPALTAPLLLVHGGNDTNVPPSESQ
HHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCHHH
QMFDALRALDRTVELLVFDDDGHEIVKRENRAALVNAMTTWLLKAFSAASVL
HHHHHHHHHCCEEEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10382966; 12037315 [H]