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The map label for this gene is uppS [H]

Identifier: 108800549

GI number: 108800549

Start: 3818317

End: 3818949

Strand: Reverse

Name: uppS [H]

Synonym: Mmcs_3583

Alternate gene names: 108800549

Gene position: 3818949-3818317 (Counterclockwise)

Preceding gene: 108800550

Following gene: 108800548

Centisome position: 66.94

GC content: 63.51

Gene sequence:

>633_bases
GTGGGATTGATTCCCGACGGGTTACGGCGCTGGGCGGACGCCAATAAAGCCACATTGGTCGACGCGTACCGGCGCGGAGC
GATGAAAGTCGTCGATATTCTGCTCGCACTACAAGAACACGGTGTGCAGACCGTCTCGGTATACAACCTCAGTCGCGCAA
ATCTGGCACGACGGGACGACGAGCTCGAGGCGGTGTTCGCGGCGTCGACCCACTTCTTCAGCACACTGATTCCCGCTAAC
TTCGACCACACCGCCTGTGGCGTGCGAATCCACGGCGATCTCGATCTTCTTCCGGACGAATACGTCGCTGCCGCCCGGTC
GGTGGAGCAAACGATGACCGGCCGCGATTTCCGGATCAACATCCTCGCCGCCTACGACGCCGCCGACGAACTCCGGGCGG
CCCACCGCCGGGCCCGACAGAACGGCTGCGACATCACCGCCGCTCTCGAGATCGGCGACGTCGACTTGGTCATCCGCACC
ACGCCCGAACCCCTGCTCAGCGGATTCCTGCCTTTGCAGAGCCAGTACGCCCAGCTGATGTTCCTGACCACTGCGCTCAA
CGATCTCCAACGCGCGGACATCGACGATCTGATCGCCGACTACCGACGCTTCCCGCAGCGGCGTGGGCGGTGA

Upstream 100 bases:

>100_bases
GTTCTCGCAGTGCTCCGTCCCACCGAAGAATAGCTTTTCCACGGGCAAATTCCGTTACACTCAATAAGTGCACTTATCGC
CGCCGGGGGGGCCGGCGCAC

Downstream 100 bases:

>100_bases
CGCCATGGAGCCCGACAGGAATCCGCTGATCATCGGCGCCGGGCCCGCCGGTCTCACCGCTGCACTGCAACTGGTGAAGC
GCGGGGTCACGCCGCGGATC

Product: di-trans-poly-cis-decaprenylcistransferase

Products: NA

Alternate protein names: UPP synthase; Di-trans,poly-cis-decaprenylcistransferase; Undecaprenyl diphosphate synthase; UDS [H]

Number of amino acids: Translated: 210; Mature: 209

Protein sequence:

>210_residues
MGLIPDGLRRWADANKATLVDAYRRGAMKVVDILLALQEHGVQTVSVYNLSRANLARRDDELEAVFAASTHFFSTLIPAN
FDHTACGVRIHGDLDLLPDEYVAAARSVEQTMTGRDFRINILAAYDAADELRAAHRRARQNGCDITAALEIGDVDLVIRT
TPEPLLSGFLPLQSQYAQLMFLTTALNDLQRADIDDLIADYRRFPQRRGR

Sequences:

>Translated_210_residues
MGLIPDGLRRWADANKATLVDAYRRGAMKVVDILLALQEHGVQTVSVYNLSRANLARRDDELEAVFAASTHFFSTLIPAN
FDHTACGVRIHGDLDLLPDEYVAAARSVEQTMTGRDFRINILAAYDAADELRAAHRRARQNGCDITAALEIGDVDLVIRT
TPEPLLSGFLPLQSQYAQLMFLTTALNDLQRADIDDLIADYRRFPQRRGR
>Mature_209_residues
GLIPDGLRRWADANKATLVDAYRRGAMKVVDILLALQEHGVQTVSVYNLSRANLARRDDELEAVFAASTHFFSTLIPANF
DHTACGVRIHGDLDLLPDEYVAAARSVEQTMTGRDFRINILAAYDAADELRAAHRRARQNGCDITAALEIGDVDLVIRTT
PEPLLSGFLPLQSQYAQLMFLTTALNDLQRADIDDLIADYRRFPQRRGR

Specific function: Generates undecaprenyl pyrophosphate (UPP) from isopentenyl pyrophosphate (IPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide [H]

COG id: COG0020

COG function: function code I; Undecaprenyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPP synthase family [H]

Homologues:

Organism=Drosophila melanogaster, GI18857969, Length=198, Percent_Identity=26.2626262626263, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001441
- InterPro:   IPR018520 [H]

Pfam domain/function: PF01255 Prenyltransf [H]

EC number: =2.5.1.31 [H]

Molecular weight: Translated: 23440; Mature: 23309

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLIPDGLRRWADANKATLVDAYRRGAMKVVDILLALQEHGVQTVSVYNLSRANLARRDD
CCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCC
ELEAVFAASTHFFSTLIPANFDHTACGVRIHGDLDLLPDEYVAAARSVEQTMTGRDFRIN
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEE
ILAAYDAADELRAAHRRARQNGCDITAALEIGDVDLVIRTTPEPLLSGFLPLQSQYAQLM
EEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCHHHHHHCCHHHHHHHHHH
FLTTALNDLQRADIDDLIADYRRFPQRRGR
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLIPDGLRRWADANKATLVDAYRRGAMKVVDILLALQEHGVQTVSVYNLSRANLARRDD
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCC
ELEAVFAASTHFFSTLIPANFDHTACGVRIHGDLDLLPDEYVAAARSVEQTMTGRDFRIN
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCEEEE
ILAAYDAADELRAAHRRARQNGCDITAALEIGDVDLVIRTTPEPLLSGFLPLQSQYAQLM
EEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCEEEEEECCCHHHHHHCCHHHHHHHHHH
FLTTALNDLQRADIDDLIADYRRFPQRRGR
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]