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The map label for this gene is tig [H]

Identifier: 108800545

GI number: 108800545

Start: 3810909

End: 3812345

Strand: Reverse

Name: tig [H]

Synonym: Mmcs_3579

Alternate gene names: 108800545

Gene position: 3812345-3810909 (Counterclockwise)

Preceding gene: 108800546

Following gene: 108800544

Centisome position: 66.82

GC content: 68.55

Gene sequence:

>1437_bases
GTGAAGAGCACCGTCGAGAAGTTGAGCCCCACCCGGGTGCGCATCAACGTGGAGGTGCCCTTCACGGAACTCGAACCGGA
CTTCGACCGGGCGTTCAAGGAGCTCGCCAAGCAGGTGCGGCTCCCCGGGTTCCGGCCCGGTAAGGCGCCGCGCAAGCTGC
TCGAGGCCCGCGTCGGCCGCGAGGCCATGCTCGACCAGGTCGTCGGCGAGGCCGTCCCCGGCCGCTACACCGAGGCCGTG
ACGAGCTCGGACGTGCAGCCCCTCGGGCAGCCCGAGATCGAGATCACCAAGAAGGAGTACGGCGAGGACCTGGTGTTCAC
CGCCGAGGTCGACGTCCGTCCCGAGATCACCCTGCCGGACCTGTCCGCGCTGGAGATCACCGTCGACCCGATCGAGATCA
CCGACGAGGAGGTCGACACCGAACTGCAGTCCCTGCGCGCCCGCTTCGGCACGCTGACCGGTGTCGACCGTCCGGCAAAG
GACGGCGACTTCGTCTCCATCGACCTGTCTGCCACCGTCGACGGGAAGGACGTCCCGGAGGCGACCACCGAGGGCCTGTC
GCACGAGGTGGGCTCGGGCCAGCTGATCGAGGGCCTCGACGATGCGATCGTCGGCCTCTCGGAGGGGGAGAGCAAGGAGT
TCACCACCACGCTGGCCGCCGGCGAGCACGCAGGCAAAGAGGCCATCGTCACCGTCACGGTGAAGTCCATCAAGGAACGT
GAACTGCCGGAGCCGGACGATGAGTTCGCCCAGCTCGCCAGCGAATTCGACACCATCGACGAGCTCAAGGAGAGCCTGAC
CGAGCAGGTCCGTCGGGTGAAGCGCGTCCAGCAGGCCGAGCAGATCCGCGACAAGGCGCTGGAGCTGCTGCTCGAGCAGA
CCGAGGTCCCGCTGCCCGAGAAGATCGTCCAGGCCCAGATCGACGACACTGTCCACAACGCGATCCACGGCCTCGACCAC
GACGAGGACCGCTTCGCCGAGCAGCTCGCCGAACAGGGCAGCAGCCGCGAGGAGTTCGACGCCAACACCCGCACCGAGGC
CGAGAAGGCCGTCAAGACGCAGCTGCTGATGGATGCGCTCGCCGACCAACTCGAGGTCCAGGTCGGCCAGGGCGACCTGA
CCGAGCGGCTGGTGCTGATGTCGCGGCAGTACGGGCTCGAGCCGCAGCAGCTGCTGCAGATCCTGCAGCAGAACAACCAG
CTGCCCGCCATGTTCGCCGACGTCCGCCGCGGCCTGACCATCGCGGCCGTCGTGCACGGCGCCACGGTCAAGGACACCGA
CGGCAACGACATCGACACCACCGAGTTCTTCGGCCCGTCGGGCGGTGCGCAGGCCGAGGCGGAGGGCGCCGACGAGGCCG
ACGCCGACTCCGACGCCGACTCCGACACGGAAGCCGACTCCGACACCGAAGCCGACGAGGCCGACGAGGCCAAGTGA

Upstream 100 bases:

>100_bases
GAGCGGAAGGCCGCAGGTTCAAATCCTGTCACCCCGACAACCAGCACCGGTATGACCCAGCACGATATGACGAAGTACCC
AGACATGAGGAGAGACCGCA

Downstream 100 bases:

>100_bases
CGCTGTGAGCGAACGCTCGCCTGTCAGGGAGTGCACGCTCACGCAGGTTGGTTAGTGTCGAGAAGACATCGACGAACACA
CCGCGAACTGGCGGACCCCA

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MKSTVEKLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAPRKLLEARVGREAMLDQVVGEAVPGRYTEAV
TSSDVQPLGQPEIEITKKEYGEDLVFTAEVDVRPEITLPDLSALEITVDPIEITDEEVDTELQSLRARFGTLTGVDRPAK
DGDFVSIDLSATVDGKDVPEATTEGLSHEVGSGQLIEGLDDAIVGLSEGESKEFTTTLAAGEHAGKEAIVTVTVKSIKER
ELPEPDDEFAQLASEFDTIDELKESLTEQVRRVKRVQQAEQIRDKALELLLEQTEVPLPEKIVQAQIDDTVHNAIHGLDH
DEDRFAEQLAEQGSSREEFDANTRTEAEKAVKTQLLMDALADQLEVQVGQGDLTERLVLMSRQYGLEPQQLLQILQQNNQ
LPAMFADVRRGLTIAAVVHGATVKDTDGNDIDTTEFFGPSGGAQAEAEGADEADADSDADSDTEADSDTEADEADEAK

Sequences:

>Translated_478_residues
MKSTVEKLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAPRKLLEARVGREAMLDQVVGEAVPGRYTEAV
TSSDVQPLGQPEIEITKKEYGEDLVFTAEVDVRPEITLPDLSALEITVDPIEITDEEVDTELQSLRARFGTLTGVDRPAK
DGDFVSIDLSATVDGKDVPEATTEGLSHEVGSGQLIEGLDDAIVGLSEGESKEFTTTLAAGEHAGKEAIVTVTVKSIKER
ELPEPDDEFAQLASEFDTIDELKESLTEQVRRVKRVQQAEQIRDKALELLLEQTEVPLPEKIVQAQIDDTVHNAIHGLDH
DEDRFAEQLAEQGSSREEFDANTRTEAEKAVKTQLLMDALADQLEVQVGQGDLTERLVLMSRQYGLEPQQLLQILQQNNQ
LPAMFADVRRGLTIAAVVHGATVKDTDGNDIDTTEFFGPSGGAQAEAEGADEADADSDADSDTEADSDTEADEADEAK
>Mature_478_residues
MKSTVEKLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAPRKLLEARVGREAMLDQVVGEAVPGRYTEAV
TSSDVQPLGQPEIEITKKEYGEDLVFTAEVDVRPEITLPDLSALEITVDPIEITDEEVDTELQSLRARFGTLTGVDRPAK
DGDFVSIDLSATVDGKDVPEATTEGLSHEVGSGQLIEGLDDAIVGLSEGESKEFTTTLAAGEHAGKEAIVTVTVKSIKER
ELPEPDDEFAQLASEFDTIDELKESLTEQVRRVKRVQQAEQIRDKALELLLEQTEVPLPEKIVQAQIDDTVHNAIHGLDH
DEDRFAEQLAEQGSSREEFDANTRTEAEKAVKTQLLMDALADQLEVQVGQGDLTERLVLMSRQYGLEPQQLLQILQQNNQ
LPAMFADVRRGLTIAAVVHGATVKDTDGNDIDTTEFFGPSGGAQAEAEGADEADADSDADSDTEADSDTEADEADEAK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=313, Percent_Identity=27.1565495207668, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 52273; Mature: 52273

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTVEKLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAPRKLLEARVGR
CCCCHHHCCCCEEEEEEEECHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCH
EAMLDQVVGEAVPGRYTEAVTSSDVQPLGQPEIEITKKEYGEDLVFTAEVDVRPEITLPD
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEHHHCCCCEEEEEEECCCCCCCCCC
LSALEITVDPIEITDEEVDTELQSLRARFGTLTGVDRPAKDGDFVSIDLSATVDGKDVPE
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCH
ATTEGLSHEVGSGQLIEGLDDAIVGLSEGESKEFTTTLAAGEHAGKEAIVTVTVKSIKER
HHHHHHHHCCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHC
ELPEPDDEFAQLASEFDTIDELKESLTEQVRRVKRVQQAEQIRDKALELLLEQTEVPLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KIVQAQIDDTVHNAIHGLDHDEDRFAEQLAEQGSSREEFDANTRTEAEKAVKTQLLMDAL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHH
ADQLEVQVGQGDLTERLVLMSRQYGLEPQQLLQILQQNNQLPAMFADVRRGLTIAAVVHG
HHHHEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEC
ATVKDTDGNDIDTTEFFGPSGGAQAEAEGADEADADSDADSDTEADSDTEADEADEAK
CEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSTVEKLSPTRVRINVEVPFTELEPDFDRAFKELAKQVRLPGFRPGKAPRKLLEARVGR
CCCCHHHCCCCEEEEEEEECHHHCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCH
EAMLDQVVGEAVPGRYTEAVTSSDVQPLGQPEIEITKKEYGEDLVFTAEVDVRPEITLPD
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEHHHCCCCEEEEEEECCCCCCCCCC
LSALEITVDPIEITDEEVDTELQSLRARFGTLTGVDRPAKDGDFVSIDLSATVDGKDVPE
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCCCH
ATTEGLSHEVGSGQLIEGLDDAIVGLSEGESKEFTTTLAAGEHAGKEAIVTVTVKSIKER
HHHHHHHHCCCCCHHHHHHHHHHEECCCCCCCHHHHHHHHCCCCCCCEEEEEEHHHHHHC
ELPEPDDEFAQLASEFDTIDELKESLTEQVRRVKRVQQAEQIRDKALELLLEQTEVPLPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
KIVQAQIDDTVHNAIHGLDHDEDRFAEQLAEQGSSREEFDANTRTEAEKAVKTQLLMDAL
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHHH
ADQLEVQVGQGDLTERLVLMSRQYGLEPQQLLQILQQNNQLPAMFADVRRGLTIAAVVHG
HHHHEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEEEC
ATVKDTDGNDIDTTEFFGPSGGAQAEAEGADEADADSDADSDTEADSDTEADEADEAK
CEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA