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The map label for this gene is glpD1 [H]

Identifier: 108800338

GI number: 108800338

Start: 3573872

End: 3575428

Strand: Reverse

Name: glpD1 [H]

Synonym: Mmcs_3372

Alternate gene names: 108800338

Gene position: 3575428-3573872 (Counterclockwise)

Preceding gene: 108800339

Following gene: 108800337

Centisome position: 62.67

GC content: 72.64

Gene sequence:

>1557_bases
ATGACCTCGTCACGGAGTCCGGTCCTGAACGCGTCCCGCCGCGCCACCGAACTGAGCGCCCTCGCCGACGGTGCCCCGCT
CGACGTCGTGGTGATCGGTGGCGGGATCACCGGCACCGGTATCGCACTGGACGCCGCGAGCCGCGGGTTGTCGGTGGCGC
TGGTGGAGAAACACGATCTGGCGTTCGGCACCAGCCGCTGGAGTTCCAAACTCGTCCACGGCGGGCTTCGCTACCTGGCC
AGCGGCAACGTCGGCATCGCGCGGCGCAGCGCCGTCGAACGCGGGATCCTGATGACCCGCAACGCCCCCCACCTCGTCTC
CGCGATGCCGCAGCTCGTACCGCTGCTCCCCGAGATGGGTGGTCCGGCGCGCGCGCTGGTGCGGGCGGGATTCCTGGCGG
GCGACGGACTGCGCCGGCTGGCGGGTACGCCGGCGTCGACGCTGCCGCGCTCGCGACGCGTCACGGCCGGGCGGGCCGCC
GAGCTGGTACCGGCCGTCCGCCGCGACGGGCTGGCGGGAGCGTTCCTCGCCTACGACGGCCAGCTCATCGACGACGCCCG
CCTGGTGACCGCGGTCGCGCGAACGGCCGCCCAGCACGGCGCGCGCATCCTCACCCGCGTCGGCGCCTCCCACGCCACGG
GGACCTCCGTCCGGCTCACCGATCAGTGCACCGGCGAGTCGTTCGACGTCGCGGCGCGCGCGGTGGTCAACGCCGCGGGT
GTGTGGGCCGCCGACGTGGACGAGACGCTGCGGCTGCGGCCATCGCGGGGGACGCATCTGGTGTTCGACGCCGCGGCGTT
CGGCCACCCGACCGCCGCGCTGACCATCCCGATCCCCGGCGCGCTCAACCGGTTCGTCTTCGCGATGCCCGAACAACTCG
GCCGCGTCTACCTCGGGCTCACCGACGAGGATGCGCCCGGGCCGATACCCGATGTGCCACAACCGAGCCCACAGGAAGTC
ACCTTCCTGCTCGACACCGTCAACACCGCGCTGGCGACGACGCTGACCGCAGCCGACGTCAGAGGGGCCTACGCGGGACT
GCGCCCGCTGATCGACACCGCGCACGCGAGGAGCGAAACAGGCACCGGCGCCGGCAGCACCGCCGACCTGTCGCGCGACC
ACGCGGTGACCGAATCCCCGTCCGGCGTCATCAGCGTGATCGGCGGCAAGCTGACCGAATACCGTTACATGGCCGAAGAC
GTCCTCGACCGCGCGATCGCGCTGCGCGGTCTGACCGCGGGCCCGTGCCGCACCCGTGACCTGCCGTTGGTGGGGGCGGT
CGGCCGGGTTCCGGCGGATCTGCCTACGTCGCTGGTGGCCCGCTACGGCGCCGAGGCCCCACATGTGGTCGCCCGCGCCC
GCTGCGACCGGCCCACCGCGGCCGTGGCCGACGGAATCGACGTCACCCGTGCCGAATTCGAATACGCGGTCACCCACGAG
GGTGCGCTGACCGTCGACGACATCCTCGACCGACGCACCCGGATCGGCCTCGTCGAGGACGACCGCAACCGTGCGCTGCA
GGTGGCGAAGGAGTTCGTCGACGCACTTGTGGAGTGA

Upstream 100 bases:

>100_bases
CCCAGTCGACCATCCAATCCGCACAGATGGTCGCCCCGCTGCTCGACGAGGAGGCACTGTCGGTGGAGCTGGCGCGCTCG
TTGAACGGATACCTGCGGCC

Downstream 100 bases:

>100_bases
CGGCGGTCACATCTGGGTATCCGTGCCGGATGAGTGCAGCACCCACCTTGAAAAAGGCGCTCAACCAGCGCCAACTGCGG
ATGATCGCCATCGGCGGCGT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 517

Protein sequence:

>518_residues
MTSSRSPVLNASRRATELSALADGAPLDVVVIGGGITGTGIALDAASRGLSVALVEKHDLAFGTSRWSSKLVHGGLRYLA
SGNVGIARRSAVERGILMTRNAPHLVSAMPQLVPLLPEMGGPARALVRAGFLAGDGLRRLAGTPASTLPRSRRVTAGRAA
ELVPAVRRDGLAGAFLAYDGQLIDDARLVTAVARTAAQHGARILTRVGASHATGTSVRLTDQCTGESFDVAARAVVNAAG
VWAADVDETLRLRPSRGTHLVFDAAAFGHPTAALTIPIPGALNRFVFAMPEQLGRVYLGLTDEDAPGPIPDVPQPSPQEV
TFLLDTVNTALATTLTAADVRGAYAGLRPLIDTAHARSETGTGAGSTADLSRDHAVTESPSGVISVIGGKLTEYRYMAED
VLDRAIALRGLTAGPCRTRDLPLVGAVGRVPADLPTSLVARYGAEAPHVVARARCDRPTAAVADGIDVTRAEFEYAVTHE
GALTVDDILDRRTRIGLVEDDRNRALQVAKEFVDALVE

Sequences:

>Translated_518_residues
MTSSRSPVLNASRRATELSALADGAPLDVVVIGGGITGTGIALDAASRGLSVALVEKHDLAFGTSRWSSKLVHGGLRYLA
SGNVGIARRSAVERGILMTRNAPHLVSAMPQLVPLLPEMGGPARALVRAGFLAGDGLRRLAGTPASTLPRSRRVTAGRAA
ELVPAVRRDGLAGAFLAYDGQLIDDARLVTAVARTAAQHGARILTRVGASHATGTSVRLTDQCTGESFDVAARAVVNAAG
VWAADVDETLRLRPSRGTHLVFDAAAFGHPTAALTIPIPGALNRFVFAMPEQLGRVYLGLTDEDAPGPIPDVPQPSPQEV
TFLLDTVNTALATTLTAADVRGAYAGLRPLIDTAHARSETGTGAGSTADLSRDHAVTESPSGVISVIGGKLTEYRYMAED
VLDRAIALRGLTAGPCRTRDLPLVGAVGRVPADLPTSLVARYGAEAPHVVARARCDRPTAAVADGIDVTRAEFEYAVTHE
GALTVDDILDRRTRIGLVEDDRNRALQVAKEFVDALVE
>Mature_517_residues
TSSRSPVLNASRRATELSALADGAPLDVVVIGGGITGTGIALDAASRGLSVALVEKHDLAFGTSRWSSKLVHGGLRYLAS
GNVGIARRSAVERGILMTRNAPHLVSAMPQLVPLLPEMGGPARALVRAGFLAGDGLRRLAGTPASTLPRSRRVTAGRAAE
LVPAVRRDGLAGAFLAYDGQLIDDARLVTAVARTAAQHGARILTRVGASHATGTSVRLTDQCTGESFDVAARAVVNAAGV
WAADVDETLRLRPSRGTHLVFDAAAFGHPTAALTIPIPGALNRFVFAMPEQLGRVYLGLTDEDAPGPIPDVPQPSPQEVT
FLLDTVNTALATTLTAADVRGAYAGLRPLIDTAHARSETGTGAGSTADLSRDHAVTESPSGVISVIGGKLTEYRYMAEDV
LDRAIALRGLTAGPCRTRDLPLVGAVGRVPADLPTSLVARYGAEAPHVVARARCDRPTAAVADGIDVTRAEFEYAVTHEG
ALTVDDILDRRTRIGLVEDDRNRALQVAKEFVDALVE

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=556, Percent_Identity=31.294964028777, Blast_Score=212, Evalue=6e-55,
Organism=Homo sapiens, GI285002231, Length=556, Percent_Identity=31.294964028777, Blast_Score=212, Evalue=6e-55,
Organism=Escherichia coli, GI2367226, Length=498, Percent_Identity=29.9196787148594, Blast_Score=152, Evalue=6e-38,
Organism=Escherichia coli, GI1788574, Length=487, Percent_Identity=31.8275154004107, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17509253, Length=535, Percent_Identity=31.588785046729, Blast_Score=175, Evalue=5e-44,
Organism=Caenorhabditis elegans, GI115534726, Length=533, Percent_Identity=31.1444652908068, Blast_Score=172, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6322036, Length=568, Percent_Identity=27.4647887323944, Blast_Score=157, Evalue=4e-39,
Organism=Drosophila melanogaster, GI161077125, Length=556, Percent_Identity=31.294964028777, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653942, Length=556, Percent_Identity=31.294964028777, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24653944, Length=556, Percent_Identity=31.294964028777, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI20130025, Length=556, Percent_Identity=31.294964028777, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24586295, Length=535, Percent_Identity=28.9719626168224, Blast_Score=138, Evalue=9e-33,
Organism=Drosophila melanogaster, GI19921278, Length=526, Percent_Identity=27.3764258555133, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI45550977, Length=368, Percent_Identity=25.5434782608696, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 54074; Mature: 53943

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSSRSPVLNASRRATELSALADGAPLDVVVIGGGITGTGIALDAASRGLSVALVEKHDL
CCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCEEEEEECCCC
AFGTSRWSSKLVHGGLRYLASGNVGIARRSAVERGILMTRNAPHLVSAMPQLVPLLPEMG
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCC
GPARALVRAGFLAGDGLRRLAGTPASTLPRSRRVTAGRAAELVPAVRRDGLAGAFLAYDG
CHHHHHHHHHHHCCCCHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
QLIDDARLVTAVARTAAQHGARILTRVGASHATGTSVRLTDQCTGESFDVAARAVVNAAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC
VWAADVDETLRLRPSRGTHLVFDAAAFGHPTAALTIPIPGALNRFVFAMPEQLGRVYLGL
CEECCCCHHHEECCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCHHHHCEEEEEE
TDEDAPGPIPDVPQPSPQEVTFLLDTVNTALATTLTAADVRGAYAGLRPLIDTAHARSET
CCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTGAGSTADLSRDHAVTESPSGVISVIGGKLTEYRYMAEDVLDRAIALRGLTAGPCRTRD
CCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LPLVGAVGRVPADLPTSLVARYGAEAPHVVARARCDRPTAAVADGIDVTRAEFEYAVTHE
CCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCHHHHCCCCCCHHHEEEEEECC
GALTVDDILDRRTRIGLVEDDRNRALQVAKEFVDALVE
CCEEHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSSRSPVLNASRRATELSALADGAPLDVVVIGGGITGTGIALDAASRGLSVALVEKHDL
CCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEECCCCCCEEEEEECCCC
AFGTSRWSSKLVHGGLRYLASGNVGIARRSAVERGILMTRNAPHLVSAMPQLVPLLPEMG
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHCCC
GPARALVRAGFLAGDGLRRLAGTPASTLPRSRRVTAGRAAELVPAVRRDGLAGAFLAYDG
CHHHHHHHHHHHCCCCHHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECC
QLIDDARLVTAVARTAAQHGARILTRVGASHATGTSVRLTDQCTGESFDVAARAVVNAAG
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCC
VWAADVDETLRLRPSRGTHLVFDAAAFGHPTAALTIPIPGALNRFVFAMPEQLGRVYLGL
CEECCCCHHHEECCCCCCEEEEECCCCCCCCEEEEEECCHHHHHHHHHCHHHHCEEEEEE
TDEDAPGPIPDVPQPSPQEVTFLLDTVNTALATTLTAADVRGAYAGLRPLIDTAHARSET
CCCCCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GTGAGSTADLSRDHAVTESPSGVISVIGGKLTEYRYMAEDVLDRAIALRGLTAGPCRTRD
CCCCCCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
LPLVGAVGRVPADLPTSLVARYGAEAPHVVARARCDRPTAAVADGIDVTRAEFEYAVTHE
CCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHCCCCCHHHHCCCCCCHHHEEEEEECC
GALTVDDILDRRTRIGLVEDDRNRALQVAKEFVDALVE
CCEEHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]