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The map label for this gene is adhB [H]

Identifier: 108800148

GI number: 108800148

Start: 3373213

End: 3374319

Strand: Reverse

Name: adhB [H]

Synonym: Mmcs_3182

Alternate gene names: 108800148

Gene position: 3374319-3373213 (Counterclockwise)

Preceding gene: 108800149

Following gene: 108800147

Centisome position: 59.14

GC content: 61.52

Gene sequence:

>1107_bases
ATGAAGACACGTGCGGCTGTTTTGTGGGGCTTGGAGCAGAAGTGGGAGGTCGAAGAAGTCGATTTGGATCCGCCAGGTCC
CGGGGAGGTCCTCGTGCGGCTGGCGGCCACCGGCTTGTGCCATTCCGACGAACATCTGGTGACCGGCGACCTCCCGATCC
CATTGCCGGTAGTGGGGGGTCATGAGGGTGCTGGCACAGTCGTGGAGTGCGGCGAAGGGGTTGAGGAACTGTCCGAAGGT
GATTCTGTCATCTTGACCTTCCTTCCCTCGTGTGGGCGCTGCTCGTACTGCGCGCGCGGCATGGGCAATCTCTGTGAGTT
GGGAGCGGCGCTCATGATGGGACCGCAGATCGACGGCACCTATCGCTTTCACGCACGAGGCGAGGACGTCGGGCAGATGT
GTTTGCTCGGGACGTTTTCCGAGTACACAGTGGTGCCGCAGGCGTCCGTGGTCAAGATTGACGGCGGAATCCCCCTGGAT
CGGGCAGCCTTGATCGGTTGCGGCGTCACGACCGGTTACGGATCTGCGGTGCGGACTGGGGAGGTGCGCGCCGGGGACAC
CGTCGTGGTAGTGGGAGCGGGCGGAATCGGAATGAATGCGATTCAGGGCGCGCGAATCGCGGGAGCGCTGGCGATTGTGG
CGGTCGATCCGGTGAAGTTCAAGCGAGAGCAAGCGAGCGGGTTCGGTGCGACGCACACCGCGGCCTCGATGGATGAAGCT
TGGTCGCTGGTCAGCGATATGACGCTGGGCAAGCTGGCTGATGTCTGCATCCTCACCACCGATGTGGCTGAGGCCTCCTA
CACCGCGGAAGCGCTGGCCTTGGTCGGAAAGCGCGGGCGCGTCGTGGTCACGGCCATCGGGCACCCCGACGACTCATCGA
TCTCAGGATCACTGCTTGAAATGACGCTTTACGAGAAGCAGATTCGTGGCGCTTTGTATGGCTCATCCAATGCGCCGCAC
GATATTCCGCGACTGGTCGAGCTGTACTCCGCTGGGTTGTTGAAGCTCGATGAGTTGGTCACCCGCGAATACTCCCTCGA
CCAAATTAATGAGGGCTACCAGGATATGCGTTCAGGAAAAAATATCCGAGGGCTGGTCCGGTTCTGA

Upstream 100 bases:

>100_bases
GGGCGATGTGCCCGGAGATCATCCAGGACAGTTCGCGCGACCACCGTGCGCGGTCGGGATAACTACTCGAGAAGCGTAAT
TCGATAGAAGGGACTTCAAC

Downstream 100 bases:

>100_bases
AGAGCATCATGCCCACTGCTGGTCTCCATGTCCTTGCGTTGCTGCAGATCATGCGGCCGGGCCCCTTGGGTGGTTGGCGT
CGGGTCCTTCTTTCCCGTCG

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKTRAAVLWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVTGDLPIPLPVVGGHEGAGTVVECGEGVEELSEG
DSVILTFLPSCGRCSYCARGMGNLCELGAALMMGPQIDGTYRFHARGEDVGQMCLLGTFSEYTVVPQASVVKIDGGIPLD
RAALIGCGVTTGYGSAVRTGEVRAGDTVVVVGAGGIGMNAIQGARIAGALAIVAVDPVKFKREQASGFGATHTAASMDEA
WSLVSDMTLGKLADVCILTTDVAEASYTAEALALVGKRGRVVVTAIGHPDDSSISGSLLEMTLYEKQIRGALYGSSNAPH
DIPRLVELYSAGLLKLDELVTREYSLDQINEGYQDMRSGKNIRGLVRF

Sequences:

>Translated_368_residues
MKTRAAVLWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVTGDLPIPLPVVGGHEGAGTVVECGEGVEELSEG
DSVILTFLPSCGRCSYCARGMGNLCELGAALMMGPQIDGTYRFHARGEDVGQMCLLGTFSEYTVVPQASVVKIDGGIPLD
RAALIGCGVTTGYGSAVRTGEVRAGDTVVVVGAGGIGMNAIQGARIAGALAIVAVDPVKFKREQASGFGATHTAASMDEA
WSLVSDMTLGKLADVCILTTDVAEASYTAEALALVGKRGRVVVTAIGHPDDSSISGSLLEMTLYEKQIRGALYGSSNAPH
DIPRLVELYSAGLLKLDELVTREYSLDQINEGYQDMRSGKNIRGLVRF
>Mature_368_residues
MKTRAAVLWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVTGDLPIPLPVVGGHEGAGTVVECGEGVEELSEG
DSVILTFLPSCGRCSYCARGMGNLCELGAALMMGPQIDGTYRFHARGEDVGQMCLLGTFSEYTVVPQASVVKIDGGIPLD
RAALIGCGVTTGYGSAVRTGEVRAGDTVVVVGAGGIGMNAIQGARIAGALAIVAVDPVKFKREQASGFGATHTAASMDEA
WSLVSDMTLGKLADVCILTTDVAEASYTAEALALVGKRGRVVVTAIGHPDDSSISGSLLEMTLYEKQIRGALYGSSNAPH
DIPRLVELYSAGLLKLDELVTREYSLDQINEGYQDMRSGKNIRGLVRF

Specific function: Has High Formaldehyde Dehydrogenase Activity In The Presence Of Glutathione And Catalyzes The Oxidation Of Normal Alcohols In A Reaction That Is Not Gsh-Dependent. In Addition, Hemithiolacetals Other Than Those Formed From Gsh, Including Omega-Thiol Fatty

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=377, Percent_Identity=38.4615384615385, Blast_Score=241, Evalue=6e-64,
Organism=Homo sapiens, GI34577061, Length=377, Percent_Identity=38.1962864721485, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI262073058, Length=375, Percent_Identity=36, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI71743840, Length=375, Percent_Identity=36, Blast_Score=231, Evalue=8e-61,
Organism=Homo sapiens, GI4501929, Length=372, Percent_Identity=36.5591397849462, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI71565154, Length=375, Percent_Identity=36, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI156523966, Length=372, Percent_Identity=35.4838709677419, Blast_Score=214, Evalue=8e-56,
Organism=Homo sapiens, GI4501939, Length=366, Percent_Identity=35.5191256830601, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI71565152, Length=377, Percent_Identity=32.6259946949602, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI156627571, Length=360, Percent_Identity=26.9444444444444, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1786552, Length=386, Percent_Identity=34.9740932642487, Blast_Score=178, Evalue=5e-46,
Organism=Escherichia coli, GI87082125, Length=383, Percent_Identity=26.1096605744125, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787863, Length=337, Percent_Identity=25.5192878338279, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1786825, Length=372, Percent_Identity=27.1505376344086, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790045, Length=349, Percent_Identity=26.647564469914, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI226510992, Length=359, Percent_Identity=27.5766016713092, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1788407, Length=335, Percent_Identity=25.9701492537313, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788073, Length=376, Percent_Identity=24.468085106383, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786518, Length=378, Percent_Identity=28.3068783068783, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1788075, Length=365, Percent_Identity=24.9315068493151, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87081918, Length=339, Percent_Identity=29.2035398230088, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25146526, Length=385, Percent_Identity=31.6883116883117, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI71997431, Length=387, Percent_Identity=31.5245478036176, Blast_Score=188, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17565904, Length=355, Percent_Identity=31.830985915493, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI71988145, Length=375, Percent_Identity=29.0666666666667, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17562584, Length=352, Percent_Identity=29.2613636363636, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562876, Length=371, Percent_Identity=27.4932614555256, Blast_Score=101, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17562582, Length=373, Percent_Identity=30.0268096514745, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17562878, Length=370, Percent_Identity=26.7567567567568, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=385, Percent_Identity=34.8051948051948, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6323729, Length=364, Percent_Identity=25.8241758241758, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6319621, Length=341, Percent_Identity=28.1524926686217, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323961, Length=364, Percent_Identity=27.4725274725275, Blast_Score=99, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319257, Length=345, Percent_Identity=28.1159420289855, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324486, Length=209, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323099, Length=353, Percent_Identity=25.4957507082153, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322619, Length=338, Percent_Identity=27.2189349112426, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319955, Length=338, Percent_Identity=27.2189349112426, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319258, Length=369, Percent_Identity=24.1192411924119, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737895, Length=380, Percent_Identity=35, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI17137530, Length=363, Percent_Identity=26.4462809917355, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI17737897, Length=366, Percent_Identity=27.3224043715847, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 38627; Mature: 38627

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTRAAVLWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVTGDLPIPLPVVGG
CCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEECC
HEGAGTVVECGEGVEELSEGDSVILTFLPSCGRCSYCARGMGNLCELGAALMMGPQIDGT
CCCCCCCEECCCCHHHHHCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCE
YRFHARGEDVGQMCLLGTFSEYTVVPQASVVKIDGGIPLDRAALIGCGVTTGYGSAVRTG
EEEEECCCCHHCEEEEECCCCEEECCCCEEEEECCCCCCCHHHEEECCCCCCCCCCEECC
EVRAGDTVVVVGAGGIGMNAIQGARIAGALAIVAVDPVKFKREQASGFGATHTAASMDEA
CCCCCCEEEEEECCCCCCHHHCCCHHHCEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
WSLVSDMTLGKLADVCILTTDVAEASYTAEALALVGKRGRVVVTAIGHPDDSSISGSLLE
HHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHH
MTLYEKQIRGALYGSSNAPHDIPRLVELYSAGLLKLDELVTREYSLDQINEGYQDMRSGK
HHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCCHHHHHCCC
NIRGLVRF
CCEEEECC
>Mature Secondary Structure
MKTRAAVLWGLEQKWEVEEVDLDPPGPGEVLVRLAATGLCHSDEHLVTGDLPIPLPVVGG
CCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEECC
HEGAGTVVECGEGVEELSEGDSVILTFLPSCGRCSYCARGMGNLCELGAALMMGPQIDGT
CCCCCCCEECCCCHHHHHCCCEEEEEECCCCCCHHHHHHCCCHHHHHHHHHHCCCCCCCE
YRFHARGEDVGQMCLLGTFSEYTVVPQASVVKIDGGIPLDRAALIGCGVTTGYGSAVRTG
EEEEECCCCHHCEEEEECCCCEEECCCCEEEEECCCCCCCHHHEEECCCCCCCCCCEECC
EVRAGDTVVVVGAGGIGMNAIQGARIAGALAIVAVDPVKFKREQASGFGATHTAASMDEA
CCCCCCEEEEEECCCCCCHHHCCCHHHCEEEEEEECCHHHHHHHCCCCCCCCHHHHHHHH
WSLVSDMTLGKLADVCILTTDVAEASYTAEALALVGKRGRVVVTAIGHPDDSSISGSLLE
HHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHH
MTLYEKQIRGALYGSSNAPHDIPRLVELYSAGLLKLDELVTREYSLDQINEGYQDMRSGK
HHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCCHHHHHCCC
NIRGLVRF
CCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]