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The map label for this gene is gltB [H]

Identifier: 108800009

GI number: 108800009

Start: 3215429

End: 3216937

Strand: Reverse

Name: gltB [H]

Synonym: Mmcs_3043

Alternate gene names: 108800009

Gene position: 3216937-3215429 (Counterclockwise)

Preceding gene: 108800010

Following gene: 108800008

Centisome position: 56.38

GC content: 70.25

Gene sequence:

>1509_bases
GTGGCTGATCCCACCGGATTCCTGAAGGTGCCCAAGGTCGAAGCCGCCAAGCGGCCCGTCGACGAGCGCGTCGGCGACTG
GCACGAAGTGTACGAACGTCAGAGCCTGCCCGAGCGTGCCGAAGAGGTCTCGCAGCAGGCGCGGCGCTGTATGGACTGCG
GAATCCCGTTCTGCCACTCCGGTTCTGCCGGCTGCCCGCTGGGGAACCTGATCCCCGAGTGGAACGACCTGGTGCGCCGG
GGACGCTGGGACGCCGCCAGCGAACGCCTGCACGCCACCAACAACTTCCCGGAGTTCACCGGACGGCTGTGCCCGGCGCC
GTGCGAGGCGGCCTGCGTGCTCTCGATCAGCGAGGACCACACCGGCGGCAGCGTCACGATCAAACGCATCGAGAACACGA
TCGCCGATCAGGCGTGGGCGCTGGGCCTCGTCGACCCTCAACCGGCGTCGATCCGCACCGGTAGGCGGGTCGCCGTCGTG
GGCTCCGGTCCTGCGGGTCTCGCTGCGGCCCAACAGCTCACGCGCGCCGGACACGACGTCACGGTCTTCGAACGCGACGA
CCGCATCGGCGGGCTCATGCGTTACGGCATCCCCGAGTACAAGTTGGAGAAGAGGACCCTCGACCAGCGGTTGGCGCAGA
TGCGCGCGGAGGGCACCCGATTTGTCACCGAGTGCGAGGTGGGCGTCGACCTGACCGTGGAACAACTGCGAGAACGGCAC
GACGCCGTGGTCCTGGCTGTCGGTGCGCTGCGCGCCAGGGACAACGACGTCGAGGGCCGCCACCTCGACGGTGTGCACCT
GGCGATGGAGCACCTGGTGCCGGCCAACAAGGAATGCGGGGGTGACGGCCCGTCCACGCTGTCCGCGCGGGACAAGCACG
TCGTGATCATCGGCGGCGGGGACACCGGCGCGGACTGCCTGGGCACCGCGCACCGCCAGGGGGCGGCTTCGGTCACCCAA
CTCGACTACAACCCGGAACCGCCGGAGACCCGTGACGACACCCGCACGCCGTGGCCGATGTGGCCGCTGGTGTTGCGGAC
CCGGCTGTCGCCGGCGCACGCCGAGGGTGGGCAGCGCCGCTATCAGGTTGCGGTCCAGCGCTTCCTGGGTGACGAGCAGG
GGCGCGTACGGGGCATGGAGATCGCCGAGGTCAAGGTGGAACGCGACGCCGAGGGCCGCAGGCAGATCGTGCCCGTCGGC
GAGACGCTCGAGATCCCCTGCGATATGGCCTTGCTCGCGATCGGATTCGAGGGCGTCGAGCACATGCCCCTGCTCGACGG
GCTCGGACTGAGCCTGAACAATCGCGGCGCGCTGCCCTGCGGCAGTGACTGGCAGACCGATGCGCCCGGGGTGTTCGTCT
GTGGCGACGCCCACCGCGGCGCATCGCTGATCGTGTGGGCGATCGCCGAAGGCCGCAGCGCCGCCCACGCCGTCGACGCG
TATCTGATGGGGGAGTCCGACCTGCCGGCGCCGGTGCGACCCGGCGCGCTGCCACTGGCCGTCGTCTGA

Upstream 100 bases:

>100_bases
ACCAAAATCATGCCCAGCGACTACCAGCGCGTCCTGGAGGCCACCCGGATGGCGAAGGCCGAGGGACGCGACGTCGACAC
CGCGATCATGGAGGCCAGCC

Downstream 100 bases:

>100_bases
ATCGATCAACGACTACGATGAGTCAACGTGAATAGACGCGGGAAGATCGTCTGTACCCTCGGTCCGGCCACCGGCTCCGA
CGACGCCGTCCGGAAGCTGG

Product: glutamate synthase (NADH) small subunit

Products: NA

Alternate protein names: NADPH-GOGAT [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MADPTGFLKVPKVEAAKRPVDERVGDWHEVYERQSLPERAEEVSQQARRCMDCGIPFCHSGSAGCPLGNLIPEWNDLVRR
GRWDAASERLHATNNFPEFTGRLCPAPCEAACVLSISEDHTGGSVTIKRIENTIADQAWALGLVDPQPASIRTGRRVAVV
GSGPAGLAAAQQLTRAGHDVTVFERDDRIGGLMRYGIPEYKLEKRTLDQRLAQMRAEGTRFVTECEVGVDLTVEQLRERH
DAVVLAVGALRARDNDVEGRHLDGVHLAMEHLVPANKECGGDGPSTLSARDKHVVIIGGGDTGADCLGTAHRQGAASVTQ
LDYNPEPPETRDDTRTPWPMWPLVLRTRLSPAHAEGGQRRYQVAVQRFLGDEQGRVRGMEIAEVKVERDAEGRRQIVPVG
ETLEIPCDMALLAIGFEGVEHMPLLDGLGLSLNNRGALPCGSDWQTDAPGVFVCGDAHRGASLIVWAIAEGRSAAHAVDA
YLMGESDLPAPVRPGALPLAVV

Sequences:

>Translated_502_residues
MADPTGFLKVPKVEAAKRPVDERVGDWHEVYERQSLPERAEEVSQQARRCMDCGIPFCHSGSAGCPLGNLIPEWNDLVRR
GRWDAASERLHATNNFPEFTGRLCPAPCEAACVLSISEDHTGGSVTIKRIENTIADQAWALGLVDPQPASIRTGRRVAVV
GSGPAGLAAAQQLTRAGHDVTVFERDDRIGGLMRYGIPEYKLEKRTLDQRLAQMRAEGTRFVTECEVGVDLTVEQLRERH
DAVVLAVGALRARDNDVEGRHLDGVHLAMEHLVPANKECGGDGPSTLSARDKHVVIIGGGDTGADCLGTAHRQGAASVTQ
LDYNPEPPETRDDTRTPWPMWPLVLRTRLSPAHAEGGQRRYQVAVQRFLGDEQGRVRGMEIAEVKVERDAEGRRQIVPVG
ETLEIPCDMALLAIGFEGVEHMPLLDGLGLSLNNRGALPCGSDWQTDAPGVFVCGDAHRGASLIVWAIAEGRSAAHAVDA
YLMGESDLPAPVRPGALPLAVV
>Mature_501_residues
ADPTGFLKVPKVEAAKRPVDERVGDWHEVYERQSLPERAEEVSQQARRCMDCGIPFCHSGSAGCPLGNLIPEWNDLVRRG
RWDAASERLHATNNFPEFTGRLCPAPCEAACVLSISEDHTGGSVTIKRIENTIADQAWALGLVDPQPASIRTGRRVAVVG
SGPAGLAAAQQLTRAGHDVTVFERDDRIGGLMRYGIPEYKLEKRTLDQRLAQMRAEGTRFVTECEVGVDLTVEQLRERHD
AVVLAVGALRARDNDVEGRHLDGVHLAMEHLVPANKECGGDGPSTLSARDKHVVIIGGGDTGADCLGTAHRQGAASVTQL
DYNPEPPETRDDTRTPWPMWPLVLRTRLSPAHAEGGQRRYQVAVQRFLGDEQGRVRGMEIAEVKVERDAEGRRQIVPVGE
TLEIPCDMALLAIGFEGVEHMPLLDGLGLSLNNRGALPCGSDWQTDAPGVFVCGDAHRGASLIVWAIAEGRSAAHAVDAY
LMGESDLPAPVRPGALPLAVV

Specific function: Unknown

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamate synthase family [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=292, Percent_Identity=23.6301369863014, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1788811, Length=482, Percent_Identity=37.551867219917, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI1789606, Length=489, Percent_Identity=35.5828220858896, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI87082180, Length=485, Percent_Identity=35.0515463917526, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1789243, Length=452, Percent_Identity=27.6548672566372, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788468, Length=445, Percent_Identity=26.5168539325843, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17570289, Length=500, Percent_Identity=42.4, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI71984108, Length=292, Percent_Identity=26.027397260274, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17543860, Length=155, Percent_Identity=33.5483870967742, Blast_Score=73, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320030, Length=497, Percent_Identity=41.851106639839, Blast_Score=375, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28574881, Length=495, Percent_Identity=47.2727272727273, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24665539, Length=495, Percent_Identity=47.2727272727273, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24665547, Length=495, Percent_Identity=47.2727272727273, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24665543, Length=495, Percent_Identity=47.2727272727273, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24640763, Length=509, Percent_Identity=25.147347740668, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI18858217, Length=509, Percent_Identity=25.147347740668, Blast_Score=97, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006005
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 54355; Mature: 54224

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPTGFLKVPKVEAAKRPVDERVGDWHEVYERQSLPERAEEVSQQARRCMDCGIPFCHS
CCCCCCCEECCCHHHHCCCHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
GSAGCPLGNLIPEWNDLVRRGRWDAASERLHATNNFPEFTGRLCPAPCEAACVLSISEDH
CCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHCCCCCCCCCCEEEEEECCCC
TGGSVTIKRIENTIADQAWALGLVDPQPASIRTGRRVAVVGSGPAGLAAAQQLTRAGHDV
CCCCEEHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCE
TVFERDDRIGGLMRYGIPEYKLEKRTLDQRLAQMRAEGTRFVTECEVGVDLTVEQLRERH
EEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHC
DAVVLAVGALRARDNDVEGRHLDGVHLAMEHLVPANKECGGDGPSTLSARDKHVVIIGGG
CEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECC
DTGADCLGTAHRQGAASVTQLDYNPEPPETRDDTRTPWPMWPLVLRTRLSPAHAEGGQRR
CCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHH
YQVAVQRFLGDEQGRVRGMEIAEVKVERDAEGRRQIVPVGETLEIPCDMALLAIGFEGVE
HHHHHHHHHCCCCCCEECCEEEEEEEECCCCCCEEEEECCCCEECCCCCEEEECCCCCCC
HMPLLDGLGLSLNNRGALPCGSDWQTDAPGVFVCGDAHRGASLIVWAIAEGRSAAHAVDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHE
YLMGESDLPAPVRPGALPLAVV
EEECCCCCCCCCCCCCCCEEEC
>Mature Secondary Structure 
ADPTGFLKVPKVEAAKRPVDERVGDWHEVYERQSLPERAEEVSQQARRCMDCGIPFCHS
CCCCCCEECCCHHHHCCCHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCC
GSAGCPLGNLIPEWNDLVRRGRWDAASERLHATNNFPEFTGRLCPAPCEAACVLSISEDH
CCCCCCCCCCCCCHHHHHHCCCCCHHHHHHHCCCCCHHHHCCCCCCCCCCEEEEEECCCC
TGGSVTIKRIENTIADQAWALGLVDPQPASIRTGRRVAVVGSGPAGLAAAQQLTRAGHDV
CCCCEEHHHHHHHHHHHHEEEECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCE
TVFERDDRIGGLMRYGIPEYKLEKRTLDQRLAQMRAEGTRFVTECEVGVDLTVEQLRERH
EEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHC
DAVVLAVGALRARDNDVEGRHLDGVHLAMEHLVPANKECGGDGPSTLSARDKHVVIIGGG
CEEEEEEEHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECC
DTGADCLGTAHRQGAASVTQLDYNPEPPETRDDTRTPWPMWPLVLRTRLSPAHAEGGQRR
CCCHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHH
YQVAVQRFLGDEQGRVRGMEIAEVKVERDAEGRRQIVPVGETLEIPCDMALLAIGFEGVE
HHHHHHHHHCCCCCCEECCEEEEEEEECCCCCCEEEEECCCCEECCCCCEEEECCCCCCC
HMPLLDGLGLSLNNRGALPCGSDWQTDAPGVFVCGDAHRGASLIVWAIAEGRSAAHAVDA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEEEEECCCCHHHHHHE
YLMGESDLPAPVRPGALPLAVV
EEECCCCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11029411 [H]