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The map label for this gene is gbh [H]

Identifier: 108799990

GI number: 108799990

Start: 3194868

End: 3195809

Strand: Reverse

Name: gbh [H]

Synonym: Mmcs_3024

Alternate gene names: 108799990

Gene position: 3195809-3194868 (Counterclockwise)

Preceding gene: 108799992

Following gene: 108799988

Centisome position: 56.01

GC content: 67.94

Gene sequence:

>942_bases
ATGGACACACCCATTGGCCCCGTCGACGCAACCAAAGTGCCCCGCTTTGCCGGGCCCGCCACCTTCGCGCGCCTGCCGCG
CATCGACGAGGTGACCCGCACCGACGTCGCGGTCGTGGGTGTGCCGTTCGACTCCGGGGTGTCCTACCGACCGGGAGCCC
GGTTCGGTCCCGCCCACATCCGGGCCTCCTCGAAGCTGCTCCGCACGTACCATCCGCGTCTCGACGTCGAACCGTTTGCG
GTACAACAGGTGGTCGATGCCGGCGACATCGCGGTGAACCCGTTCGACATCGCCGAGGCCATCACGGCCATCGAACGGCA
CTCCGACGAATTACGCAGCGGCGGTGCGAAACTGGTGACGCTCGGCGGCGACCACACGATCGCGCTACCACTGCTGCGAT
CGCTGCACCGCGAGCACGGCCCGATCGCGGTGCTGCACTTCGACGCCCACCTCGACACCTGGGACACCTACTTCGGTGCG
CCGTTCACCCACGGCACACCGTTCAGGCGCGCCGGCGAGGAAGGGTTGCTCGATCCCGAGCACTGCCTGCACGTCGGTAT
CCGCGGACCCCTGTACGCACCCACGGACCTGTCCGACGACCGGGTGCTCGGCTTCCAGGTCGTCGGATCCGACGACTATC
AACTCGAGGGTCTCGCCACGGTGATCGAACGTATGCGGGCGCGGATCGGAGACGCACCGGTATACGTGTCGGTGGACATC
GACGTCCTCGACCCGGCCCACGCGCCGGGTACAGGTACGCCGGAGGCCGGCGGGATGACGAGCAGAGAACTGCTGCTCTC
CCTGCGGAGTCTGGTCGGTGCCAACGTGGTCGGAGCGGACATCGTCGAGGTCGCGCCCGCCTACGACCACGCCGAGATCA
CCGGGATCGCCGCCGCACACGTGGCCTACGAACTCATCTCGGTGTTGGCCGCCAACCGGTGA

Upstream 100 bases:

>100_bases
ATCGGGCACACAGACGGCGCGCGAAGCGTCGCGGACGGCCATTGACGCAGCGTATCGCCGGGGACGCGCGGAATCGGGCG
TTCTCGACGAGGCTGGTTCC

Downstream 100 bases:

>100_bases
GCGGCCAGACGCCGGGCATCGCCTGGCGCCCAATCGGTCCCGGTGCCGCGCTATTGAGCCGACAGAGGTCACCCGGCGGG
GAGTGTGATCATCGCCGTGG

Product: agmatinase

Products: NA

Alternate protein names: GBase; D-arginase [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MDTPIGPVDATKVPRFAGPATFARLPRIDEVTRTDVAVVGVPFDSGVSYRPGARFGPAHIRASSKLLRTYHPRLDVEPFA
VQQVVDAGDIAVNPFDIAEAITAIERHSDELRSGGAKLVTLGGDHTIALPLLRSLHREHGPIAVLHFDAHLDTWDTYFGA
PFTHGTPFRRAGEEGLLDPEHCLHVGIRGPLYAPTDLSDDRVLGFQVVGSDDYQLEGLATVIERMRARIGDAPVYVSVDI
DVLDPAHAPGTGTPEAGGMTSRELLLSLRSLVGANVVGADIVEVAPAYDHAEITGIAAAHVAYELISVLAANR

Sequences:

>Translated_313_residues
MDTPIGPVDATKVPRFAGPATFARLPRIDEVTRTDVAVVGVPFDSGVSYRPGARFGPAHIRASSKLLRTYHPRLDVEPFA
VQQVVDAGDIAVNPFDIAEAITAIERHSDELRSGGAKLVTLGGDHTIALPLLRSLHREHGPIAVLHFDAHLDTWDTYFGA
PFTHGTPFRRAGEEGLLDPEHCLHVGIRGPLYAPTDLSDDRVLGFQVVGSDDYQLEGLATVIERMRARIGDAPVYVSVDI
DVLDPAHAPGTGTPEAGGMTSRELLLSLRSLVGANVVGADIVEVAPAYDHAEITGIAAAHVAYELISVLAANR
>Mature_313_residues
MDTPIGPVDATKVPRFAGPATFARLPRIDEVTRTDVAVVGVPFDSGVSYRPGARFGPAHIRASSKLLRTYHPRLDVEPFA
VQQVVDAGDIAVNPFDIAEAITAIERHSDELRSGGAKLVTLGGDHTIALPLLRSLHREHGPIAVLHFDAHLDTWDTYFGA
PFTHGTPFRRAGEEGLLDPEHCLHVGIRGPLYAPTDLSDDRVLGFQVVGSDDYQLEGLATVIERMRARIGDAPVYVSVDI
DVLDPAHAPGTGTPEAGGMTSRELLLSLRSLVGANVVGADIVEVAPAYDHAEITGIAAAHVAYELISVLAANR

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=297, Percent_Identity=41.0774410774411, Blast_Score=243, Evalue=2e-64,
Organism=Homo sapiens, GI10947139, Length=302, Percent_Identity=25.4966887417219, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789306, Length=296, Percent_Identity=40.5405405405405, Blast_Score=197, Evalue=6e-52,
Organism=Saccharomyces cerevisiae, GI6325146, Length=192, Percent_Identity=30.2083333333333, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.7; =3.5.3.10 [H]

Molecular weight: Translated: 33443; Mature: 33443

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTPIGPVDATKVPRFAGPATFARLPRIDEVTRTDVAVVGVPFDSGVSYRPGARFGPAHI
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHCCCCEEEEEECCCCCCCCCCCCCCCHHHH
RASSKLLRTYHPRLDVEPFAVQQVVDAGDIAVNPFDIAEAITAIERHSDELRSGGAKLVT
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCEEEE
LGGDHTIALPLLRSLHREHGPIAVLHFDAHLDTWDTYFGAPFTHGTPFRRAGEEGLLDPE
ECCCCEEHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCCCCCCCCHHHCCCCCCCCHH
HCLHVGIRGPLYAPTDLSDDRVLGFQVVGSDDYQLEGLATVIERMRARIGDAPVYVSVDI
HHEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEE
DVLDPAHAPGTGTPEAGGMTSRELLLSLRSLVGANVVGADIVEVAPAYDHAEITGIAAAH
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHH
VAYELISVLAANR
HHHHHHHHHHCCC
>Mature Secondary Structure
MDTPIGPVDATKVPRFAGPATFARLPRIDEVTRTDVAVVGVPFDSGVSYRPGARFGPAHI
CCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHCCCCEEEEEECCCCCCCCCCCCCCCHHHH
RASSKLLRTYHPRLDVEPFAVQQVVDAGDIAVNPFDIAEAITAIERHSDELRSGGAKLVT
HHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHHHHHCCCCEEEE
LGGDHTIALPLLRSLHREHGPIAVLHFDAHLDTWDTYFGAPFTHGTPFRRAGEEGLLDPE
ECCCCEEHHHHHHHHHHCCCCEEEEEEECCCCCHHHHCCCCCCCCCCHHHCCCCCCCCHH
HCLHVGIRGPLYAPTDLSDDRVLGFQVVGSDDYQLEGLATVIERMRARIGDAPVYVSVDI
HHEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEE
DVLDPAHAPGTGTPEAGGMTSRELLLSLRSLVGANVVGADIVEVAPAYDHAEITGIAAAH
EEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCHHHHHHHHHH
VAYELISVLAANR
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA