Click here to switch to the map view.

The map label for this gene is cmk [H]

Identifier: 108799894

GI number: 108799894

Start: 3085338

End: 3086024

Strand: Reverse

Name: cmk [H]

Synonym: Mmcs_2928

Alternate gene names: 108799894

Gene position: 3086024-3085338 (Counterclockwise)

Preceding gene: 108799895

Following gene: 108799893

Centisome position: 54.09

GC content: 71.76

Gene sequence:

>687_bases
GTGACTGACGGAACGGTGATCGCCGTCGACGGCCCCGCCGGCACCGGAAAGTCCTCGGTGTCAAGGGGTTTGGCTCGCGC
GCTGGGCGCCCGGTATCTCGACACCGGGGCGATGTACCGCATCGTGACCCTGGCCGTGCTGCGCGCGGGCATCGATCCCT
CCGACGGGGACGCGGTGGCCGCTGCCGTCGACGGGGTCGAGCTCGCGGTCGGCTACGACCCCGACGAGGACCGCTCTTTG
CTTGCGGGAGAAGATGTTTCGGCCGAGATCCGCGGAGACGCCGTCACGCGGGCGGTGTCGGCGGTGTCGGCGGTGCCCGC
GGTGCGCGCGCGGCTGGTGGACCTGCAGCGCCGGCTGGCGGACGGATCGGGCAGCGTGGTCGTCGAGGGGCGCGACATCG
GGACCGTGGTGCTGCCCGCCGCCGACGTCAAGATCTTCCTCACCGCCTCGGCCGAGGAGCGGGCGCGCAGGCGCAACGTG
CAGAACGTCGCCAACGGACTGCCCGACGACTACGACTCCGTCCTGGCCGACGTCCGGCGTCGCGACCATCTGGACTCGAC
CCGGGCCGTCTCGCCGCTGCGCGCGGCCGACGACGCCGTGGTCGTCGACACCAGCGATATGAACGAAACCGAAGTGGTCG
CGCATCTGCAGGATCTGGTGCACCAGCGGGCGGGAGTGCGCCGATGA

Upstream 100 bases:

>100_bases
GCACCGACATCGGGGCGGTCTCGCTCGGCGAGCAGCGCCCCGGCAGCATTCGGGTGTTGACCCGCAAGGAGATCGGTGAA
CTGTACAAGGCGGTGGGGAT

Downstream 100 bases:

>100_bases
CATCACCAGAGGACGACGGCACCTGGGTCGACGAACGGGACTGGGAGCTGGGTGCCGAAGAGGTCGCCGAGGCGATCGAG
GAGGCGTCCGCCCCACCCCC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTDGTVIAVDGPAGTGKSSVSRGLARALGARYLDTGAMYRIVTLAVLRAGIDPSDGDAVAAAVDGVELAVGYDPDEDRSL
LAGEDVSAEIRGDAVTRAVSAVSAVPAVRARLVDLQRRLADGSGSVVVEGRDIGTVVLPAADVKIFLTASAEERARRRNV
QNVANGLPDDYDSVLADVRRRDHLDSTRAVSPLRAADDAVVVDTSDMNETEVVAHLQDLVHQRAGVRR

Sequences:

>Translated_228_residues
MTDGTVIAVDGPAGTGKSSVSRGLARALGARYLDTGAMYRIVTLAVLRAGIDPSDGDAVAAAVDGVELAVGYDPDEDRSL
LAGEDVSAEIRGDAVTRAVSAVSAVPAVRARLVDLQRRLADGSGSVVVEGRDIGTVVLPAADVKIFLTASAEERARRRNV
QNVANGLPDDYDSVLADVRRRDHLDSTRAVSPLRAADDAVVVDTSDMNETEVVAHLQDLVHQRAGVRR
>Mature_227_residues
TDGTVIAVDGPAGTGKSSVSRGLARALGARYLDTGAMYRIVTLAVLRAGIDPSDGDAVAAAVDGVELAVGYDPDEDRSLL
AGEDVSAEIRGDAVTRAVSAVSAVPAVRARLVDLQRRLADGSGSVVVEGRDIGTVVLPAADVKIFLTASAEERARRRNVQ
NVANGLPDDYDSVLADVRRRDHLDSTRAVSPLRAADDAVVVDTSDMNETEVVAHLQDLVHQRAGVRR

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787139, Length=208, Percent_Identity=40.3846153846154, Blast_Score=148, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003136
- InterPro:   IPR011994 [H]

Pfam domain/function: PF02224 Cytidylate_kin [H]

EC number: =2.7.4.14 [H]

Molecular weight: Translated: 23892; Mature: 23761

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDGTVIAVDGPAGTGKSSVSRGLARALGARYLDTGAMYRIVTLAVLRAGIDPSDGDAVA
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEE
AAVDGVELAVGYDPDEDRSLLAGEDVSAEIRGDAVTRAVSAVSAVPAVRARLVDLQRRLA
EEECCEEEEECCCCCCCCCEECCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGSGSVVVEGRDIGTVVLPAADVKIFLTASAEERARRRNVQNVANGLPDDYDSVLADVRR
CCCCCEEEECCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RDHLDSTRAVSPLRAADDAVVVDTSDMNETEVVAHLQDLVHQRAGVRR
HHCCCHHHHCCCHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDGTVIAVDGPAGTGKSSVSRGLARALGARYLDTGAMYRIVTLAVLRAGIDPSDGDAVA
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCEEE
AAVDGVELAVGYDPDEDRSLLAGEDVSAEIRGDAVTRAVSAVSAVPAVRARLVDLQRRLA
EEECCEEEEECCCCCCCCCEECCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGSGSVVVEGRDIGTVVLPAADVKIFLTASAEERARRRNVQNVANGLPDDYDSVLADVRR
CCCCCEEEECCCCCEEEEECCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
RDHLDSTRAVSPLRAADDAVVVDTSDMNETEVVAHLQDLVHQRAGVRR
HHCCCHHHHCCCHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]