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The map label for this gene is engA [H]

Identifier: 108799893

GI number: 108799893

Start: 3083926

End: 3085341

Strand: Reverse

Name: engA [H]

Synonym: Mmcs_2927

Alternate gene names: 108799893

Gene position: 3085341-3083926 (Counterclockwise)

Preceding gene: 108799894

Following gene: 108799892

Centisome position: 54.08

GC content: 70.06

Gene sequence:

>1416_bases
ATGACATCACCAGAGGACGACGGCACCTGGGTCGACGAACGGGACTGGGAGCTGGGTGCCGAAGAGGTCGCCGAGGCGAT
CGAGGAGGCGTCCGCCCCACCCCCGGTGGTAGCCGTCGTCGGCCGTCCCAACGTCGGCAAGTCGACGCTGGTGAACCGGA
TCCTGGGCCGGCGTGAGGCGGTGGTGCAGGACATCCCCGGCGTCACGCGCGACCGCGTCTCCTACGACGCGACCTGGTCC
GGACGCCGTTTCGTCGTACAGGACACCGGCGGCTGGGAACCCGACGCCAAGGGCCTGCAGCAGCTGGTCGCCGACCAGGC
CACCGTCGCGATGCGCACCGCCGACGCGATCATCCTGGTCGTCGACGCCGTCGTCGGCGCGACCGCCGCCGACGAAGCCG
CCGCGCGGATGCTGCGCAAATCGGGCAAACCGGTGTTCCTGGCCGCCAACAAGGTCGACACCGAACGCGGAGAGGCCGAT
GCGGCCGCGCTGTGGTCGCTGGGGATCGGTCAGCCGCATTCGGTGAGCGCCATCCACGGCCGCGGCGTCGCCGATCTGCT
CGACCATGTCCTCGAGAAACTGCCCGAGGTGTCCGAGGTCGGCGGGGGATCCGGCGGTCCGCGCCGCGTCGCGCTCGTCG
GCAAACCGAACGTGGGCAAGAGCTCGCTGCTCAACCGGCTCGCCGGGGACGAACGGTCGGTGGTGCACGACGTCGCCGGG
ACGACGGTCGACCCGGTCGACTCGCTGATCGAACTCGGCGGCAAGACGTGGCGGTTCGTCGACACGGCCGGGCTGCGCCG
CAAGGTCGGGCAGGCCAGCGGCCACGAGTTCTACGCCTCGGTGCGCACCCACGGCGCCATCGACGCGGCCGAAGTCGTGC
TCGTGCTGATCGACGCCTCCCAACCGCTGACCGAACAGGACCAGCGGGTGCTGTCGATGGTCATCGAGGCCGGCCGGGCA
CTGGTGCTCGCCTTCAACAAGTGGGACCTCGTCGACGAGGACCGCCGCTATCTACTGGACCGGGAAATCGACCGGGAGCT
GGCGCAGGTGCAGTGGGCGCCGCGGGTCAACATCTCGGCGATGACCGGCCGGGCCGTGCAGAAGCTGGTGCCGGCCCTGG
AGACGGCGCTGCAATCGTGGGACGCCCGCATCCCGACCGGCCGGCTCAACACGTTCTTCAAGGAGATCGTGGCCGCCACG
CCGCCTCCCGTGCGGGGCGGCAAGCAGCCCAGGATCCTGTTCGCCACCCAGGCCACCGCACGGCCTCCGACGTTCGTGTT
GTTCACCAGCGGTTTCCTCGAGGCGGGCTATCGTCGGTTCCTCGAGCGGCGGCTGCGTGAGACCTTCGGATTCGAGGGCA
GCCCCATCCGGATCAACGTTCGGGTACGCGAGAAGCGCGGTTCACGATCGCGCTAG

Upstream 100 bases:

>100_bases
CGGCCGACGACGCCGTGGTCGTCGACACCAGCGATATGAACGAAACCGAAGTGGTCGCGCATCTGCAGGATCTGGTGCAC
CAGCGGGCGGGAGTGCGCCG

Downstream 100 bases:

>100_bases
TACAGTGTGAAGATCAGCAGACGACGAGAGGGGACGACGGTGGCTGAACGAGCCTTCCGTGCCGCACCCTCGCACGCCTG
CGCCCTTCAGCCCTTCTGGC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MTSPEDDGTWVDERDWELGAEEVAEAIEEASAPPPVVAVVGRPNVGKSTLVNRILGRREAVVQDIPGVTRDRVSYDATWS
GRRFVVQDTGGWEPDAKGLQQLVADQATVAMRTADAIILVVDAVVGATAADEAAARMLRKSGKPVFLAANKVDTERGEAD
AAALWSLGIGQPHSVSAIHGRGVADLLDHVLEKLPEVSEVGGGSGGPRRVALVGKPNVGKSSLLNRLAGDERSVVHDVAG
TTVDPVDSLIELGGKTWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDAAEVVLVLIDASQPLTEQDQRVLSMVIEAGRA
LVLAFNKWDLVDEDRRYLLDREIDRELAQVQWAPRVNISAMTGRAVQKLVPALETALQSWDARIPTGRLNTFFKEIVAAT
PPPVRGGKQPRILFATQATARPPTFVLFTSGFLEAGYRRFLERRLRETFGFEGSPIRINVRVREKRGSRSR

Sequences:

>Translated_471_residues
MTSPEDDGTWVDERDWELGAEEVAEAIEEASAPPPVVAVVGRPNVGKSTLVNRILGRREAVVQDIPGVTRDRVSYDATWS
GRRFVVQDTGGWEPDAKGLQQLVADQATVAMRTADAIILVVDAVVGATAADEAAARMLRKSGKPVFLAANKVDTERGEAD
AAALWSLGIGQPHSVSAIHGRGVADLLDHVLEKLPEVSEVGGGSGGPRRVALVGKPNVGKSSLLNRLAGDERSVVHDVAG
TTVDPVDSLIELGGKTWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDAAEVVLVLIDASQPLTEQDQRVLSMVIEAGRA
LVLAFNKWDLVDEDRRYLLDREIDRELAQVQWAPRVNISAMTGRAVQKLVPALETALQSWDARIPTGRLNTFFKEIVAAT
PPPVRGGKQPRILFATQATARPPTFVLFTSGFLEAGYRRFLERRLRETFGFEGSPIRINVRVREKRGSRSR
>Mature_470_residues
TSPEDDGTWVDERDWELGAEEVAEAIEEASAPPPVVAVVGRPNVGKSTLVNRILGRREAVVQDIPGVTRDRVSYDATWSG
RRFVVQDTGGWEPDAKGLQQLVADQATVAMRTADAIILVVDAVVGATAADEAAARMLRKSGKPVFLAANKVDTERGEADA
AALWSLGIGQPHSVSAIHGRGVADLLDHVLEKLPEVSEVGGGSGGPRRVALVGKPNVGKSSLLNRLAGDERSVVHDVAGT
TVDPVDSLIELGGKTWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDAAEVVLVLIDASQPLTEQDQRVLSMVIEAGRAL
VLAFNKWDLVDEDRRYLLDREIDRELAQVQWAPRVNISAMTGRAVQKLVPALETALQSWDARIPTGRLNTFFKEIVAATP
PPVRGGKQPRILFATQATARPPTFVLFTSGFLEAGYRRFLERRLRETFGFEGSPIRINVRVREKRGSRSR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=456, Percent_Identity=35.7456140350877, Blast_Score=272, Evalue=3e-74,
Organism=Escherichia coli, GI1788919, Length=125, Percent_Identity=34.4, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=40.2173913043478, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17507259, Length=127, Percent_Identity=34.6456692913386, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=180, Percent_Identity=29.4444444444444, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI45550813, Length=146, Percent_Identity=32.1917808219178, Blast_Score=66, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51129; Mature: 50997

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSPEDDGTWVDERDWELGAEEVAEAIEEASAPPPVVAVVGRPNVGKSTLVNRILGRREA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
VVQDIPGVTRDRVSYDATWSGRRFVVQDTGGWEPDAKGLQQLVADQATVAMRTADAIILV
HHHHCCCCCHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
VDAVVGATAADEAAARMLRKSGKPVFLAANKVDTERGEADAAALWSLGIGQPHSVSAIHG
HHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
RGVADLLDHVLEKLPEVSEVGGGSGGPRRVALVGKPNVGKSSLLNRLAGDERSVVHDVAG
CCHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCC
TTVDPVDSLIELGGKTWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDAAEVVLVLIDAS
CCCHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEEEECC
QPLTEQDQRVLSMVIEAGRALVLAFNKWDLVDEDRRYLLDREIDRELAQVQWAPRVNISA
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEH
MTGRAVQKLVPALETALQSWDARIPTGRLNTFFKEIVAATPPPVRGGKQPRILFATQATA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
RPPTFVLFTSGFLEAGYRRFLERRLRETFGFEGSPIRINVRVREKRGSRSR
CCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TSPEDDGTWVDERDWELGAEEVAEAIEEASAPPPVVAVVGRPNVGKSTLVNRILGRREA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHH
VVQDIPGVTRDRVSYDATWSGRRFVVQDTGGWEPDAKGLQQLVADQATVAMRTADAIILV
HHHHCCCCCHHCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHH
VDAVVGATAADEAAARMLRKSGKPVFLAANKVDTERGEADAAALWSLGIGQPHSVSAIHG
HHHHHCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCC
RGVADLLDHVLEKLPEVSEVGGGSGGPRRVALVGKPNVGKSSLLNRLAGDERSVVHDVAG
CCHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHHCC
TTVDPVDSLIELGGKTWRFVDTAGLRRKVGQASGHEFYASVRTHGAIDAAEVVLVLIDAS
CCCHHHHHHHHCCCCEEEEEEHHHHHHHHCCCCCCHHHHHHHHCCCCCCEEEEEEEEECC
QPLTEQDQRVLSMVIEAGRALVLAFNKWDLVDEDRRYLLDREIDRELAQVQWAPRVNISA
CCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEH
MTGRAVQKLVPALETALQSWDARIPTGRLNTFFKEIVAATPPPVRGGKQPRILFATQATA
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
RPPTFVLFTSGFLEAGYRRFLERRLRETFGFEGSPIRINVRVREKRGSRSR
CCCEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA