| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is ppsB [H]
Identifier: 108799799
GI number: 108799799
Start: 2986831
End: 2991393
Strand: Reverse
Name: ppsB [H]
Synonym: Mmcs_2833
Alternate gene names: 108799799
Gene position: 2991393-2986831 (Counterclockwise)
Preceding gene: 108799800
Following gene: 108799798
Centisome position: 52.43
GC content: 69.14
Gene sequence:
>4563_bases ATGGCTGCTGCGACGCCGGACCGGCGTGCGATCATCACCGAGGCGCTGCGCAAGATCGACGATCTCACTGCCCGTTTGGA GGTCGCCGAACGGGGTCAGTACGAGCCGATCGCGGTGGTCGGGATGGGGTGCCGGCTGCCCGGCGGGGTCTCGGACCCCG ATGGGTTCTGGCAGCTGCTGCAAGACGGTCGCTCCGGGATCGTCCGGGTGCCGCCGAAGCGGTGGGATGCCGACGAATAC TACAGCGCCGACACCTCGGTTCCCGGCACGATCTGCACACGCGAGGGTGGGTTCCTGACCGGTTGGGAGCCAGACGAATT CGATGCGGAGTTCTTCGGGATCTCGCCGCGGGAAGCCGCCGCGATGGATCCACAGCAGCGACTGCTGCTCGAGGTGGCCT GGGAAGCGCTCGAACACGCGGGAATCACACCGGACCGCATCCGGGGATCACAGACGTCGGTGTTCGTCGGGATGACGGGC TACGACTACATGCTCAAGCTCTCCGACGGCCTGGACCGCGAGGAGTACGACGCCTACGTGCCGTTCGGGAATGCGGCGAA TTTCGCGGCGGGGCGGTTGTCGTATTTCCTGGGGGTGCGGGGTCCGGCGGTGGTGGTGGACACGGCGTGTTCGTCGTCGT TGGTGTCGGTGCATCTGGCGTGTCAGAGCCTGCGCCGCCGCGAGAGTGACACCGCGCTGGCCGCCGGCGTCAACCTCATG CTCAAGGCGGAAGCCAACGTCGCGCTGTCCCGGTGGGGGATGCTCGCGCCGGACGGGCAGTGCAAGACCTTCGATGCCGG TGCCGACGGGTATGTGCGCAGCGAGGGTTGCGGTGTGGTCGTGCTCAAGCGCCTCGGGGACGCGCTGGCCGACGGTGACC GGGTGCTCGCACTGGTGCGAGGCTCGGCGGTCAATCAGGACGGGGCCAGCAGTGGGCAGACGGTGCCCAACGGCCCGGCG CAGCAGGCGTTGATGCGTCAGGCGTTGGCTGCCTCGCAGTTGGGTCCGGCCGACATCGATTACATCGAGGCGCACGGCAC GGGTACGGCGTTGGGTGATCCGATCGAATTGGATGCGCTCAGTGCGGTGTTCGGTGATCGCGGGGACGCGGCACCGTTGG TGTTGGGGTCGGTCAAGACCAACCTCGGACACCTCGAATCCGGAGCGGGCATCACGGGTTTCATCAAGACGGTGCTCAGC CTGCGGTACGGGTACATCCCCAAGCACTTGAACTTCACCCAGTTGACTCCGCATGCGGGGCCGGGTGCGTCGCAGTTCAC CATCGCCACCGACGGGATGGAGTGGCCCGCGGTGACGCGGGCGCGACGGGCGGGTGTGTCCTCGTTCGGCGTCAGCGGCA CGAACGCGCACATCATCCTCGAGCAGGCGCCGGACGTGGTGGCCGCCGAACCCGCACCGGACCCCGCGGTGTGCACGCTG GTGCTCTCGGGCAAAACCGAGAAACGAATCGCCACAACGGCAGAAGCGTTGGCCGAGTGGATGACCGGCCCGGGCAGCGC CGTCGGATTGGCCGAGGTGGCTCACACGCTCAACCACCATCGGGCGCGGCACGCCAAGTTCGCGACGGTGTGCGCGCGGG ACCAGGGGCAGGCGGTGGCGGGTCTGCGGGCGTTGGCCGCCGGTCAGGCCGCACCGGGTGTGGTCAATCCGCACGACGGG CCGTGTGGGTCGGGGACGGTGTTCGTGTTCTCGGGTCAGGGGTCGCAGTGGGCGGGGATGGGTCGGCGGCTGTTGGCCGA TGAGCCGGTGTTCGCGGCGGCGGTGGCCGAGTTGGAGCCGGTGTTCGTCGAGCAGGTCGGGTTCTCGCTGGCTCAGGTGC TCGCCGATGGTGAGGCGGTCACCGGGGATGCTCGGGTGCAGCCGGTGATCGTGGGGTTGCAGTTGGCGCTGACCGAGTTG TGGCGCTCCTACGGGGTGACCCCGGATGCGGTGATCGGTCATTCGATGGGTGAGGTCACCGCGGCGGTGGTGGCCGGTGC GCTGTCGGTGCGCGACGGGCTGCGGGTGATCGCGATCCGGTCCCGGCTGATGTCCCGACTGGCCGGCCAGGGCGCAGTCG CCCTCCTGGAACTTGATGCGCCTGCCGCAGAGGCGGTCATCCGATCGCACCCGCAGGTGGAGATCGCGGGCTTCGTGTCA CCGACCCAAACGGTGGTGGCCGGTCCGCCGGCGGCGGTGGCCGCAGTCATCGATGAGGTCACCGACGCGGGGAAGTTCGC GCGGCGGGTGAACATGGAGGTCGCCTCCCACACCGCGCTGATGGATCCCATCCTCGGCGAATTGCATGACGAGCTGGCCG ATCTCACGCCACAGACACCCGATATCCCGTTCTTCTCCACCGTGGCGGACAGCATCTCGGCTCCGCTGCTCGACGCGAAC TACTGGGTGGCCAACGTGCGGCGGCCGGTGCGGTTGCACCAGGCGGTGTCGGCCGCAGCCGACGCCGGGCACACCACCTT CGTCGAGATCAGCCCACACCCGATCCTCGCGCACGCCGTTGCCGAGACTCTCGGCGAGAACCACCACCACGCGATCGGCA CGCTGGCCCGCGACACCGACGACACCCACACCTTCCGCACCAACCTCAACTCCGCGCACACCATCCGGCCACCGGCCACC CCGCACGCGCCGGAGCCTCACCCCCAACTGCCCACCACGCCGTGGCACCACACCCGCCACTGGTTCGATTCCGCGCGACC TCAACGCACCACGCAGCACAGCGGGCGGCGCAGCACCGCGCCGGCGGCCGGTGACGTCATCCCCGCCGAGTGGCGCTGCG AACTGGTCTGGCACGCAGAACCTCCGACCACACCCGCCGACACCACCGCGCACCATTGGCTCGTCATCGGCAGCGCCGAC CTCGCCGCCCCGCTGACCGGCGCCGGCCACTCCGCGACCGTCCTCGCCGAAGGGGCGCTCGACGACCACGGCGCACTCGC CGATGCCCTGGCCGGTGCCACCCACGTGCTGTACGCACCGGCAACCACATCCGGGGTCTTCGACGCGGCGCCCGGCCGTC GGTTGTTCGATGCGGCCAGAACCCTCGTCGACCACCTCGCGCAGGCACCGACGCCAGCGAAGCTGTGGATCCTCACCCGC AATGCACAGCCCATCGACGAGGGGGACAGGGCGAATCCCGGGCACGCAGTGCTGTGGGGGCTGGGCCGCACACTCGCACT CGAACACCCCGAACTGTGGGGCAAGGTCGTCGACGTCGACGAACTCGTCCCCGCCGAACTCGTGGCCCGCTATCTGGTCG GTGAAGCCGCGGCCGGAGACGAGGACCAGATCGTCTACCGGGCCGGGGTTCGCCGGGTTCCCCGGCTGCACCGGCACGGC AACACCGCCGGCTCACAGGCGTCGATCGATCCGGACGCCGCGCACCTCGTCGTCGGTGCCACCGGCAACATCGGGCCGCA TCTGGTCCAGCAGTTGGCCGATATGGGTGCCCGCACCATCGTCGCGGTATCCCGTAACCCGGGCACGCGGTTGCAGCACC TCACCCAGACGTTGGCGGACCGGGGAGTCACCCTCACCACGGTCGCGGCGGACGCCTCCGACGAACCCTCGATGACGCCG CTGTTCCAGCGGTTCGGCACCGATCTGCCCCCACTCGGCGGTATCTACCTCGCCGCATTCGGTGGGGGACCGGTGACGCT CCTCGACCTGACCGACGACGACGTCACCACCATGTTCACCGCGAAACTCGATGCGGCGGCGGTATTGCACCGGCTGTCGC TGGCGCATCCGGTGCGCCAATTCGTCCTCTTCACCTCCATCTCCGGGTTGATCGGGTCACGCTGGTTGGCGCACTACACC GCCACCACCACGTTCCTGGACACGTTCGCCTACGCCCGTCGGGCGGCCGGACTTCCTGCCACCGCGATCAACTGGGGATT CTGGAAATCCCTGGCGGACAACGAGTCCGACGAATACCGCCAGGTCACCATCAACTCCGGGCTGGAACCGATGCCCGACG AGGTCGCCATCCAGGCGCTCTGGTCGACGATCGGGCCCGACAGCCCGGTGCGGTCGACGGTCGTCGCCGCCGACTGGACC CGGCTGGGCGCCGCCTACCGGACCCGCGCGCCCATGCACATCCTCGACGACCTCACCACCACGGACGTCGACGACGGGGC CACCGGCGAGGGTTGGGTGGGAGTCGAATCCGTCCGGGAGATGGACGCGGCCGACGCGCGGCGCGTGATCGCCGACAGGA CGCTCACTCGCCTGGCCGGCGTCCTCGGTTATGCCGACTCCTCGGCGCTCAACCCGGCGGTGCCGTTGATCGAGTTCGGG ATGGATTCGTTGATGGCCGTGCGGATCCGGCAGGCGACCCGCAACGACTTCGGTGTCGAACCTCCCGTGTCCCTGCTCCT GCAGGGCGGGTCGCTCGACGACGTGACCGCCGACGTGCTGAGTCAGTTGGGAATCGCCGAACCGGGAACGACCGCCGTCG ACGGCGTGCGTGAAAGAGCCAATCAGCGCGCCGCCGCACGTCGTGGTGCCGCAGTGCGGCGGAAGAAAGGACAATTGCTG TGA
Upstream 100 bases:
>100_bases AATCCCTCGCCGATCATCTGGTCGCGTTGGGCGAGATCGACGGGGATTCTCTCCGGGACCTCGCGACGGTGCCCCTGCCC GAGAAGGTGAGTTGAGCTCC
Downstream 100 bases:
>100_bases ACGCTCCTGCGACACCGGGCGACGTGCCACCCAACGCGGTCGCCGTCATCGGGATGGCGGCACGACTCCCGGGTGCGAAC TCGGTGTCGGCATTCTGGGA
Product: beta-ketoacyl synthase
Products: L-tryptophan [Cytoplasm]; L-tyrosine [Cytoplasm]; Proton [Cytoplasm]; L-phenylalanine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 1520; Mature: 1519
Protein sequence:
>1520_residues MAAATPDRRAIITEALRKIDDLTARLEVAERGQYEPIAVVGMGCRLPGGVSDPDGFWQLLQDGRSGIVRVPPKRWDADEY YSADTSVPGTICTREGGFLTGWEPDEFDAEFFGISPREAAAMDPQQRLLLEVAWEALEHAGITPDRIRGSQTSVFVGMTG YDYMLKLSDGLDREEYDAYVPFGNAANFAAGRLSYFLGVRGPAVVVDTACSSSLVSVHLACQSLRRRESDTALAAGVNLM LKAEANVALSRWGMLAPDGQCKTFDAGADGYVRSEGCGVVVLKRLGDALADGDRVLALVRGSAVNQDGASSGQTVPNGPA QQALMRQALAASQLGPADIDYIEAHGTGTALGDPIELDALSAVFGDRGDAAPLVLGSVKTNLGHLESGAGITGFIKTVLS LRYGYIPKHLNFTQLTPHAGPGASQFTIATDGMEWPAVTRARRAGVSSFGVSGTNAHIILEQAPDVVAAEPAPDPAVCTL VLSGKTEKRIATTAEALAEWMTGPGSAVGLAEVAHTLNHHRARHAKFATVCARDQGQAVAGLRALAAGQAAPGVVNPHDG PCGSGTVFVFSGQGSQWAGMGRRLLADEPVFAAAVAELEPVFVEQVGFSLAQVLADGEAVTGDARVQPVIVGLQLALTEL WRSYGVTPDAVIGHSMGEVTAAVVAGALSVRDGLRVIAIRSRLMSRLAGQGAVALLELDAPAAEAVIRSHPQVEIAGFVS PTQTVVAGPPAAVAAVIDEVTDAGKFARRVNMEVASHTALMDPILGELHDELADLTPQTPDIPFFSTVADSISAPLLDAN YWVANVRRPVRLHQAVSAAADAGHTTFVEISPHPILAHAVAETLGENHHHAIGTLARDTDDTHTFRTNLNSAHTIRPPAT PHAPEPHPQLPTTPWHHTRHWFDSARPQRTTQHSGRRSTAPAAGDVIPAEWRCELVWHAEPPTTPADTTAHHWLVIGSAD LAAPLTGAGHSATVLAEGALDDHGALADALAGATHVLYAPATTSGVFDAAPGRRLFDAARTLVDHLAQAPTPAKLWILTR NAQPIDEGDRANPGHAVLWGLGRTLALEHPELWGKVVDVDELVPAELVARYLVGEAAAGDEDQIVYRAGVRRVPRLHRHG NTAGSQASIDPDAAHLVVGATGNIGPHLVQQLADMGARTIVAVSRNPGTRLQHLTQTLADRGVTLTTVAADASDEPSMTP LFQRFGTDLPPLGGIYLAAFGGGPVTLLDLTDDDVTTMFTAKLDAAAVLHRLSLAHPVRQFVLFTSISGLIGSRWLAHYT ATTTFLDTFAYARRAAGLPATAINWGFWKSLADNESDEYRQVTINSGLEPMPDEVAIQALWSTIGPDSPVRSTVVAADWT RLGAAYRTRAPMHILDDLTTTDVDDGATGEGWVGVESVREMDAADARRVIADRTLTRLAGVLGYADSSALNPAVPLIEFG MDSLMAVRIRQATRNDFGVEPPVSLLLQGGSLDDVTADVLSQLGIAEPGTTAVDGVRERANQRAAARRGAAVRRKKGQLL
Sequences:
>Translated_1520_residues MAAATPDRRAIITEALRKIDDLTARLEVAERGQYEPIAVVGMGCRLPGGVSDPDGFWQLLQDGRSGIVRVPPKRWDADEY YSADTSVPGTICTREGGFLTGWEPDEFDAEFFGISPREAAAMDPQQRLLLEVAWEALEHAGITPDRIRGSQTSVFVGMTG YDYMLKLSDGLDREEYDAYVPFGNAANFAAGRLSYFLGVRGPAVVVDTACSSSLVSVHLACQSLRRRESDTALAAGVNLM LKAEANVALSRWGMLAPDGQCKTFDAGADGYVRSEGCGVVVLKRLGDALADGDRVLALVRGSAVNQDGASSGQTVPNGPA QQALMRQALAASQLGPADIDYIEAHGTGTALGDPIELDALSAVFGDRGDAAPLVLGSVKTNLGHLESGAGITGFIKTVLS LRYGYIPKHLNFTQLTPHAGPGASQFTIATDGMEWPAVTRARRAGVSSFGVSGTNAHIILEQAPDVVAAEPAPDPAVCTL VLSGKTEKRIATTAEALAEWMTGPGSAVGLAEVAHTLNHHRARHAKFATVCARDQGQAVAGLRALAAGQAAPGVVNPHDG PCGSGTVFVFSGQGSQWAGMGRRLLADEPVFAAAVAELEPVFVEQVGFSLAQVLADGEAVTGDARVQPVIVGLQLALTEL WRSYGVTPDAVIGHSMGEVTAAVVAGALSVRDGLRVIAIRSRLMSRLAGQGAVALLELDAPAAEAVIRSHPQVEIAGFVS PTQTVVAGPPAAVAAVIDEVTDAGKFARRVNMEVASHTALMDPILGELHDELADLTPQTPDIPFFSTVADSISAPLLDAN YWVANVRRPVRLHQAVSAAADAGHTTFVEISPHPILAHAVAETLGENHHHAIGTLARDTDDTHTFRTNLNSAHTIRPPAT PHAPEPHPQLPTTPWHHTRHWFDSARPQRTTQHSGRRSTAPAAGDVIPAEWRCELVWHAEPPTTPADTTAHHWLVIGSAD LAAPLTGAGHSATVLAEGALDDHGALADALAGATHVLYAPATTSGVFDAAPGRRLFDAARTLVDHLAQAPTPAKLWILTR NAQPIDEGDRANPGHAVLWGLGRTLALEHPELWGKVVDVDELVPAELVARYLVGEAAAGDEDQIVYRAGVRRVPRLHRHG NTAGSQASIDPDAAHLVVGATGNIGPHLVQQLADMGARTIVAVSRNPGTRLQHLTQTLADRGVTLTTVAADASDEPSMTP LFQRFGTDLPPLGGIYLAAFGGGPVTLLDLTDDDVTTMFTAKLDAAAVLHRLSLAHPVRQFVLFTSISGLIGSRWLAHYT ATTTFLDTFAYARRAAGLPATAINWGFWKSLADNESDEYRQVTINSGLEPMPDEVAIQALWSTIGPDSPVRSTVVAADWT RLGAAYRTRAPMHILDDLTTTDVDDGATGEGWVGVESVREMDAADARRVIADRTLTRLAGVLGYADSSALNPAVPLIEFG MDSLMAVRIRQATRNDFGVEPPVSLLLQGGSLDDVTADVLSQLGIAEPGTTAVDGVRERANQRAAARRGAAVRRKKGQLL >Mature_1519_residues AAATPDRRAIITEALRKIDDLTARLEVAERGQYEPIAVVGMGCRLPGGVSDPDGFWQLLQDGRSGIVRVPPKRWDADEYY SADTSVPGTICTREGGFLTGWEPDEFDAEFFGISPREAAAMDPQQRLLLEVAWEALEHAGITPDRIRGSQTSVFVGMTGY DYMLKLSDGLDREEYDAYVPFGNAANFAAGRLSYFLGVRGPAVVVDTACSSSLVSVHLACQSLRRRESDTALAAGVNLML KAEANVALSRWGMLAPDGQCKTFDAGADGYVRSEGCGVVVLKRLGDALADGDRVLALVRGSAVNQDGASSGQTVPNGPAQ QALMRQALAASQLGPADIDYIEAHGTGTALGDPIELDALSAVFGDRGDAAPLVLGSVKTNLGHLESGAGITGFIKTVLSL RYGYIPKHLNFTQLTPHAGPGASQFTIATDGMEWPAVTRARRAGVSSFGVSGTNAHIILEQAPDVVAAEPAPDPAVCTLV LSGKTEKRIATTAEALAEWMTGPGSAVGLAEVAHTLNHHRARHAKFATVCARDQGQAVAGLRALAAGQAAPGVVNPHDGP CGSGTVFVFSGQGSQWAGMGRRLLADEPVFAAAVAELEPVFVEQVGFSLAQVLADGEAVTGDARVQPVIVGLQLALTELW RSYGVTPDAVIGHSMGEVTAAVVAGALSVRDGLRVIAIRSRLMSRLAGQGAVALLELDAPAAEAVIRSHPQVEIAGFVSP TQTVVAGPPAAVAAVIDEVTDAGKFARRVNMEVASHTALMDPILGELHDELADLTPQTPDIPFFSTVADSISAPLLDANY WVANVRRPVRLHQAVSAAADAGHTTFVEISPHPILAHAVAETLGENHHHAIGTLARDTDDTHTFRTNLNSAHTIRPPATP HAPEPHPQLPTTPWHHTRHWFDSARPQRTTQHSGRRSTAPAAGDVIPAEWRCELVWHAEPPTTPADTTAHHWLVIGSADL AAPLTGAGHSATVLAEGALDDHGALADALAGATHVLYAPATTSGVFDAAPGRRLFDAARTLVDHLAQAPTPAKLWILTRN AQPIDEGDRANPGHAVLWGLGRTLALEHPELWGKVVDVDELVPAELVARYLVGEAAAGDEDQIVYRAGVRRVPRLHRHGN TAGSQASIDPDAAHLVVGATGNIGPHLVQQLADMGARTIVAVSRNPGTRLQHLTQTLADRGVTLTTVAADASDEPSMTPL FQRFGTDLPPLGGIYLAAFGGGPVTLLDLTDDDVTTMFTAKLDAAAVLHRLSLAHPVRQFVLFTSISGLIGSRWLAHYTA TTTFLDTFAYARRAAGLPATAINWGFWKSLADNESDEYRQVTINSGLEPMPDEVAIQALWSTIGPDSPVRSTVVAADWTR LGAAYRTRAPMHILDDLTTTDVDDGATGEGWVGVESVREMDAADARRVIADRTLTRLAGVLGYADSSALNPAVPLIEFGM DSLMAVRIRQATRNDFGVEPPVSLLLQGGSLDDVTADVLSQLGIAEPGTTAVDGVRERANQRAAARRGAAVRRKKGQLL
Specific function: Polyketide synthase involved in phenolpthiocerol synthesis [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 acyl carrier domain [H]
Homologues:
Organism=Homo sapiens, GI41872631, Length=903, Percent_Identity=30.343300110742, Blast_Score=317, Evalue=6e-86, Organism=Homo sapiens, GI8923559, Length=436, Percent_Identity=26.3761467889908, Blast_Score=105, Evalue=3e-22, Organism=Homo sapiens, GI310129082, Length=102, Percent_Identity=40.1960784313725, Blast_Score=78, Evalue=5e-14, Organism=Homo sapiens, GI310109937, Length=102, Percent_Identity=40.1960784313725, Blast_Score=78, Evalue=5e-14, Organism=Homo sapiens, GI239744023, Length=102, Percent_Identity=40.1960784313725, Blast_Score=78, Evalue=6e-14, Organism=Escherichia coli, GI1788663, Length=272, Percent_Identity=29.7794117647059, Blast_Score=97, Evalue=1e-20, Organism=Escherichia coli, GI1787337, Length=455, Percent_Identity=23.956043956044, Blast_Score=87, Evalue=1e-17, Organism=Escherichia coli, GI1787334, Length=283, Percent_Identity=30.0353356890459, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI212642053, Length=837, Percent_Identity=28.4348864994026, Blast_Score=293, Evalue=5e-79, Organism=Caenorhabditis elegans, GI17550940, Length=425, Percent_Identity=37.1764705882353, Blast_Score=255, Evalue=1e-67, Organism=Caenorhabditis elegans, GI71983541, Length=437, Percent_Identity=27.4599542334096, Blast_Score=119, Evalue=2e-26, Organism=Caenorhabditis elegans, GI71983535, Length=269, Percent_Identity=30.4832713754647, Blast_Score=109, Evalue=1e-23, Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=25.503355704698, Blast_Score=121, Evalue=1e-27, Organism=Drosophila melanogaster, GI19920632, Length=903, Percent_Identity=29.0143964562569, Blast_Score=317, Evalue=4e-86, Organism=Drosophila melanogaster, GI221330659, Length=903, Percent_Identity=29.0143964562569, Blast_Score=317, Evalue=4e-86, Organism=Drosophila melanogaster, GI24581345, Length=909, Percent_Identity=29.3729372937294, Blast_Score=315, Evalue=1e-85, Organism=Drosophila melanogaster, GI24644341, Length=439, Percent_Identity=26.1958997722096, Blast_Score=101, Evalue=5e-21,
Paralogues:
None
Copy number: 24024 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 30,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001227 - InterPro: IPR009081 - InterPro: IPR014043 - InterPro: IPR016035 - InterPro: IPR000794 - InterPro: IPR018201 - InterPro: IPR014031 - InterPro: IPR014030 - InterPro: IPR016036 - InterPro: IPR016040 - InterPro: IPR006163 - InterPro: IPR020801 - InterPro: IPR020841 - InterPro: IPR013968 - InterPro: IPR020806 - InterPro: IPR016039 - InterPro: IPR016038 [H]
Pfam domain/function: PF00698 Acyl_transf_1; PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C; PF08659 KR; PF00550 PP-binding [H]
EC number: 2.3.1.41 [C]
Molecular weight: Translated: 160480; Mature: 160349
Theoretical pI: Translated: 5.39; Mature: 5.39
Prosite motif: PS50075 ACP_DOMAIN ; PS00606 B_KETOACYL_SYNTHASE
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.7 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 2.2 %Cys+Met (Translated Protein) 0.7 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAAATPDRRAIITEALRKIDDLTARLEVAERGQYEPIAVVGMGCRLPGGVSDPDGFWQLL CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHH QDGRSGIVRVPPKRWDADEYYSADTSVPGTICTREGGFLTGWEPDEFDAEFFGISPREAA HCCCCCEEECCCCCCCCHHHCCCCCCCCCCEEECCCCEECCCCCCCCCCHHCCCCCCHHH AMDPQQRLLLEVAWEALEHAGITPDRIRGSQTSVFVGMTGYDYMLKLSDGLDREEYDAYV CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEECCCCEEEEECCCCCHHHCCCCC PFGNAANFAAGRLSYFLGVRGPAVVVDTACSSSLVSVHLACQSLRRRESDTALAAGVNLM CCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHCCEEE LKAEANVALSRWGMLAPDGQCKTFDAGADGYVRSEGCGVVVLKRLGDALADGDRVLALVR EEECCCEEHHHCCCCCCCCCCEEECCCCCCCEECCCCCCHHHHHHHHHHCCCCEEEEEEE GSAVNQDGASSGQTVPNGPAQQALMRQALAASQLGPADIDYIEAHGTGTALGDPIELDAL CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHH SAVFGDRGDAAPLVLGSVKTNLGHLESGAGITGFIKTVLSLRYGYIPKHLNFTQLTPHAG HHHHCCCCCCCCEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCC PGASQFTIATDGMEWPAVTRARRAGVSSFGVSGTNAHIILEQAPDVVAAEPAPDPAVCTL CCCCEEEEEECCCCCCHHHHHHHCCCHHCCCCCCCEEEEEECCCCEEECCCCCCCEEEEE VLSGKTEKRIATTAEALAEWMTGPGSAVGLAEVAHTLNHHRARHAKFATVCARDQGQAVA EECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH GLRALAAGQAAPGVVNPHDGPCGSGTVFVFSGQGSQWAGMGRRLLADEPVFAAAVAELEP HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCHHHCCCCHHHHHHHHHCH VFVEQVGFSLAQVLADGEAVTGDARVQPVIVGLQLALTELWRSYGVTPDAVIGHSMGEVT HHHHHHHHHHHHHHHCCCEECCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHCCCHHHHH AAVVAGALSVRDGLRVIAIRSRLMSRLAGQGAVALLELDAPAAEAVIRSHPQVEIAGFVS HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCEEEEEECC PTQTVVAGPPAAVAAVIDEVTDAGKFARRVNMEVASHTALMDPILGELHDELADLTPQTP CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC DIPFFSTVADSISAPLLDANYWVANVRRPVRLHQAVSAAADAGHTTFVEISPHPILAHAV CCCHHHHHHHHHCCCEECCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH AETLGENHHHAIGTLARDTDDTHTFRTNLNSAHTIRPPATPHAPEPHPQLPTTPWHHTRH HHHHCCCCCHHHHHHHCCCCCCHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHH WFDSARPQRTTQHSGRRSTAPAAGDVIPAEWRCELVWHAEPPTTPADTTAHHWLVIGSAD HHHCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCH LAAPLTGAGHSATVLAEGALDDHGALADALAGATHVLYAPATTSGVFDAAPGRRLFDAAR HCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHH TLVDHLAQAPTPAKLWILTRNAQPIDEGDRANPGHAVLWGLGRTLALEHPELWGKVVDVD HHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEECCHHHHCEEECHH ELVPAELVARYLVGEAAAGDEDQIVYRAGVRRVPRLHRHGNTAGSQASIDPDAAHLVVGA HCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC TGNIGPHLVQQLADMGARTIVAVSRNPGTRLQHLTQTLADRGVTLTTVAADASDEPSMTP CCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCH LFQRFGTDLPPLGGIYLAAFGGGPVTLLDLTDDDVTTMFTAKLDAAAVLHRLSLAHPVRQ HHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHH FVLFTSISGLIGSRWLAHYTATTTFLDTFAYARRAAGLPATAINWGFWKSLADNESDEYR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHCCCCCCCEE QVTINSGLEPMPDEVAIQALWSTIGPDSPVRSTVVAADWTRLGAAYRTRAPMHILDDLTT EEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEHHHHHHHHHHHCCCCHHHHHCCCC TDVDDGATGEGWVGVESVREMDAADARRVIADRTLTRLAGVLGYADSSALNPAVPLIEFG CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHC MDSLMAVRIRQATRNDFGVEPPVSLLLQGGSLDDVTADVLSQLGIAEPGTTAVDGVRERA HHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH NQRAAARRGAAVRRKKGQLL HHHHHHHHHHHHHHHCCCCC >Mature Secondary Structure AAATPDRRAIITEALRKIDDLTARLEVAERGQYEPIAVVGMGCRLPGGVSDPDGFWQLL CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHH QDGRSGIVRVPPKRWDADEYYSADTSVPGTICTREGGFLTGWEPDEFDAEFFGISPREAA HCCCCCEEECCCCCCCCHHHCCCCCCCCCCEEECCCCEECCCCCCCCCCHHCCCCCCHHH AMDPQQRLLLEVAWEALEHAGITPDRIRGSQTSVFVGMTGYDYMLKLSDGLDREEYDAYV CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEECCCCEEEEECCCCCHHHCCCCC PFGNAANFAAGRLSYFLGVRGPAVVVDTACSSSLVSVHLACQSLRRRESDTALAAGVNLM CCCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHCCEEE LKAEANVALSRWGMLAPDGQCKTFDAGADGYVRSEGCGVVVLKRLGDALADGDRVLALVR EEECCCEEHHHCCCCCCCCCCEEECCCCCCCEECCCCCCHHHHHHHHHHCCCCEEEEEEE GSAVNQDGASSGQTVPNGPAQQALMRQALAASQLGPADIDYIEAHGTGTALGDPIELDAL CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHH SAVFGDRGDAAPLVLGSVKTNLGHLESGAGITGFIKTVLSLRYGYIPKHLNFTQLTPHAG HHHHCCCCCCCCEEEECHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEECCCCCC PGASQFTIATDGMEWPAVTRARRAGVSSFGVSGTNAHIILEQAPDVVAAEPAPDPAVCTL CCCCEEEEEECCCCCCHHHHHHHCCCHHCCCCCCCEEEEEECCCCEEECCCCCCCEEEEE VLSGKTEKRIATTAEALAEWMTGPGSAVGLAEVAHTLNHHRARHAKFATVCARDQGQAVA EECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH GLRALAAGQAAPGVVNPHDGPCGSGTVFVFSGQGSQWAGMGRRLLADEPVFAAAVAELEP HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCHHHCCCCHHHHHHHHHCH VFVEQVGFSLAQVLADGEAVTGDARVQPVIVGLQLALTELWRSYGVTPDAVIGHSMGEVT HHHHHHHHHHHHHHHCCCEECCCCCCCEEEHHHHHHHHHHHHHHCCCCHHHHCCCHHHHH AAVVAGALSVRDGLRVIAIRSRLMSRLAGQGAVALLELDAPAAEAVIRSHPQVEIAGFVS HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCEEEEEECC PTQTVVAGPPAAVAAVIDEVTDAGKFARRVNMEVASHTALMDPILGELHDELADLTPQTP CCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC DIPFFSTVADSISAPLLDANYWVANVRRPVRLHQAVSAAADAGHTTFVEISPHPILAHAV CCCHHHHHHHHHCCCEECCCHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHH AETLGENHHHAIGTLARDTDDTHTFRTNLNSAHTIRPPATPHAPEPHPQLPTTPWHHTRH HHHHCCCCCHHHHHHHCCCCCCHHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCHHHHH WFDSARPQRTTQHSGRRSTAPAAGDVIPAEWRCELVWHAEPPTTPADTTAHHWLVIGSAD HHHCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEEEEEECCH LAAPLTGAGHSATVLAEGALDDHGALADALAGATHVLYAPATTSGVFDAAPGRRLFDAAR HCCCCCCCCCCEEEEECCCCCCCHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHH TLVDHLAQAPTPAKLWILTRNAQPIDEGDRANPGHAVLWGLGRTLALEHPELWGKVVDVD HHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEECCCEEEECCHHHHCEEECHH ELVPAELVARYLVGEAAAGDEDQIVYRAGVRRVPRLHRHGNTAGSQASIDPDAAHLVVGA HCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC TGNIGPHLVQQLADMGARTIVAVSRNPGTRLQHLTQTLADRGVTLTTVAADASDEPSMTP CCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCH LFQRFGTDLPPLGGIYLAAFGGGPVTLLDLTDDDVTTMFTAKLDAAAVLHRLSLAHPVRQ HHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHH FVLFTSISGLIGSRWLAHYTATTTFLDTFAYARRAAGLPATAINWGFWKSLADNESDEYR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHCCCCCCCEE QVTINSGLEPMPDEVAIQALWSTIGPDSPVRSTVVAADWTRLGAAYRTRAPMHILDDLTT EEEECCCCCCCCHHHHHHHHHHHCCCCCCHHHEEEEHHHHHHHHHHHCCCCHHHHHCCCC TDVDDGATGEGWVGVESVREMDAADARRVIADRTLTRLAGVLGYADSSALNPAVPLIEFG CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHC MDSLMAVRIRQATRNDFGVEPPVSLLLQGGSLDDVTADVLSQLGIAEPGTTAVDGVRERA HHHHHHHHHHHHHCCCCCCCCCHHHEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHH NQRAAARRGAAVRRKKGQLL HHHHHHHHHHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: 2-Mercaptoethanol; DTT; EDTA [C]
Metal ions: Phosphate [C]
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): 0.04 {acetyl-ACP}} 0.031 {acetyl-ACP}} 0.138 {cis-9-hexadecenoyl-ACP}} 0.017 {cis-9-hexadecenoyl-ACP}} 0.012 {cis-3-decenoyl-ACP}} [C]
Substrates: L-tryptophan [Periplasm]; L-tyrosine [Periplasm]; Proton [Periplasm]; L-phenylalanine [Periplasm] [C]
Specific reaction: acyl-ACP + malonyl-ACP = beta-keto-enoyl-ACP + [acyl carrier protein] + CO2 acetyl-ACP + malonyl-ACP = [acyl carrier protein] + acetoacetyl-ACP + CO2 acyl-ACP + malonyl-ACP = [acyl carrier protein] + beta-ketoacyl-ACP + CO2 malonyl-ACP = acetyl-ACP + CO2
General reaction: Acyl group transfer [C]
Inhibitor: Acetyl-CoA; Acyl-CoA; Iodoacetamide; N-Ethyl maleimide acyl -ACP-derivatives protect, malonyl -ACP-decarboxyl ation, [C]
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]