| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is glnA [H]
Identifier: 108799720
GI number: 108799720
Start: 2899651
End: 2901003
Strand: Reverse
Name: glnA [H]
Synonym: Mmcs_2754
Alternate gene names: 108799720
Gene position: 2901003-2899651 (Counterclockwise)
Preceding gene: 108799721
Following gene: 108799716
Centisome position: 50.85
GC content: 69.62
Gene sequence:
>1353_bases ATGGCAGCCAAACCCCTCGCCGCAGCCGCTATCGCGCAGCTCGAGTCCGACGGCGTCGCGACCCTCATCGGGACGGTCGT CAACCCGGCGGGGCTGACCCACGCCAAGACGGTGCCCCTACGCCGGATGGGCACCTTCGCCGACCCCGGCCTCGGGGCGA GTCCGGTGTGGCACGCCTTCACCATCGACCAGGCCGGCATCGTGTTCGGTGATGCCATCAGCGTCGTCGGCGATCAGCGG ATCCGCATCGACCTCGGCGCGCTGCGCATCCTGGGTGACGGGTTGGCCTGGGCCCCGGGCGGATTCTTCGACCAGACCGG CGGACCCGATCCGTACTGCAGCCGCGGTGCCCTGCGCCGTGTGGAGGACCGGTTGGCCGCGGCCGGGTTGACGGCCTCGG TCGGCCACGAGATGGAGTTCGTCCTCGTCGCGCCGGACGGCAGCCGGTTGCCGTCGACACTGTGGGCGCAGTACGGCCTC GCCGGGGTGCTCGAGTACGAAGGCTTCGTCCGCGACGTCACCGATGCGGCGAACAGCTCGGGGGTGCCGATCGAACAGTT CCATCCCGAGTACGGGGCCAATCAGTTCGAGATCTCGCTGCCACCGATGCCGCCGGTGGATGCGGCCGACCTGCTGGTGT TGATGCGGATCATCGTTGGCCGGGTGGCCCGCCGGCACGGTCTGCGGGTCAGCCTGTCGCCCGTCCCGTTCGCCGGTAGT GTCGGAAACGGTGCGCACCAGCACTTCTCGTTGTTGCGCGATGGCGTCCCGTTGTTCTCCGACGGGTCGGGTGCGCACGG GATGACCGCCGAGGGCGAGTCCGCCGTCGCCGGGCTGGTCGCGGGGCTGCCGGAGGCGCAGGGGGTGCTGTGCGGGTCGC TGCTGTCCGGTCTGCGTATGCAGCCGGGCCATTGGTCGGGCGCCTACATCTGCTGGGGGACCGAGAATCGCGAAGCCGCG GTGCGGTTCCTGCAGGGCTGTCAGGGCAACGTGTACGGCGGCAATGTCGAGGTCAAGGTGATCGACCCGTCGGCGAACCC GTACCTCGCCACGGCGGCCGTCCTCGGACTGGCACTCGACGGTGTCGAACGCGAGGCGACGCTGCCGCCGGAGACCGGCG TGGATCCGGCGTCGCTCACCGAAGCCCAACGGACACAAGCAGGTACGGTGTTGTTACCCGCCCGACAGCTCGACGCGTTA CGTGCTCTTGAAGGTTCCGCGACGATGCGGCGCATACTCGGGGACGAGGTCGTCGACGCGGTGGTCGCGGTGCGGCGCTA CGAGGCCGAACACTTCGGTGCGCTGTCGCCGGAGGAGCAGGCGGACAAGTTCCGGATGGCCTGGAGTCTATGA
Upstream 100 bases:
>100_bases TGGGTCGAGTCCTGCGGACACTCGACATCGGGCAGAGCTGCAAGATCACTCTGTAGATTCGGGACGCCTGCGGGTGGCCA CGAGGTGAACAATGGTCGCC
Downstream 100 bases:
>100_bases CCCCGAGTGTATGACCCCGAGTGTATGACCGTTCGCTCAGATCATGCCGGTCGCGTCGAACACCCAGGAGGTGTCTGCCG TGGCGAGGTCCTCGAGCCAG
Product: glutamine synthetase catalytic subunit
Products: NA
Alternate protein names: Glutamate--ammonia ligase [H]
Number of amino acids: Translated: 450; Mature: 449
Protein sequence:
>450_residues MAAKPLAAAAIAQLESDGVATLIGTVVNPAGLTHAKTVPLRRMGTFADPGLGASPVWHAFTIDQAGIVFGDAISVVGDQR IRIDLGALRILGDGLAWAPGGFFDQTGGPDPYCSRGALRRVEDRLAAAGLTASVGHEMEFVLVAPDGSRLPSTLWAQYGL AGVLEYEGFVRDVTDAANSSGVPIEQFHPEYGANQFEISLPPMPPVDAADLLVLMRIIVGRVARRHGLRVSLSPVPFAGS VGNGAHQHFSLLRDGVPLFSDGSGAHGMTAEGESAVAGLVAGLPEAQGVLCGSLLSGLRMQPGHWSGAYICWGTENREAA VRFLQGCQGNVYGGNVEVKVIDPSANPYLATAAVLGLALDGVEREATLPPETGVDPASLTEAQRTQAGTVLLPARQLDAL RALEGSATMRRILGDEVVDAVVAVRRYEAEHFGALSPEEQADKFRMAWSL
Sequences:
>Translated_450_residues MAAKPLAAAAIAQLESDGVATLIGTVVNPAGLTHAKTVPLRRMGTFADPGLGASPVWHAFTIDQAGIVFGDAISVVGDQR IRIDLGALRILGDGLAWAPGGFFDQTGGPDPYCSRGALRRVEDRLAAAGLTASVGHEMEFVLVAPDGSRLPSTLWAQYGL AGVLEYEGFVRDVTDAANSSGVPIEQFHPEYGANQFEISLPPMPPVDAADLLVLMRIIVGRVARRHGLRVSLSPVPFAGS VGNGAHQHFSLLRDGVPLFSDGSGAHGMTAEGESAVAGLVAGLPEAQGVLCGSLLSGLRMQPGHWSGAYICWGTENREAA VRFLQGCQGNVYGGNVEVKVIDPSANPYLATAAVLGLALDGVEREATLPPETGVDPASLTEAQRTQAGTVLLPARQLDAL RALEGSATMRRILGDEVVDAVVAVRRYEAEHFGALSPEEQADKFRMAWSL >Mature_449_residues AAKPLAAAAIAQLESDGVATLIGTVVNPAGLTHAKTVPLRRMGTFADPGLGASPVWHAFTIDQAGIVFGDAISVVGDQRI RIDLGALRILGDGLAWAPGGFFDQTGGPDPYCSRGALRRVEDRLAAAGLTASVGHEMEFVLVAPDGSRLPSTLWAQYGLA GVLEYEGFVRDVTDAANSSGVPIEQFHPEYGANQFEISLPPMPPVDAADLLVLMRIIVGRVARRHGLRVSLSPVPFAGSV GNGAHQHFSLLRDGVPLFSDGSGAHGMTAEGESAVAGLVAGLPEAQGVLCGSLLSGLRMQPGHWSGAYICWGTENREAAV RFLQGCQGNVYGGNVEVKVIDPSANPYLATAAVLGLALDGVEREATLPPETGVDPASLTEAQRTQAGTVLLPARQLDALR ALEGSATMRRILGDEVVDAVVAVRRYEAEHFGALSPEEQADKFRMAWSL
Specific function: Unknown
COG id: COG0174
COG function: function code E; Glutamine synthetase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the glutamine synthetase family [H]
Homologues:
Organism=Homo sapiens, GI221307485, Length=362, Percent_Identity=24.3093922651934, Blast_Score=71, Evalue=2e-12, Organism=Escherichia coli, GI87081870, Length=355, Percent_Identity=25.9154929577465, Blast_Score=98, Evalue=1e-21, Organism=Escherichia coli, GI1790301, Length=260, Percent_Identity=26.9230769230769, Blast_Score=87, Evalue=2e-18,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008147 - InterPro: IPR014746 - InterPro: IPR008146 - InterPro: IPR004809 - InterPro: IPR001637 [H]
Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]
EC number: =6.3.1.2 [H]
Molecular weight: Translated: 47107; Mature: 46976
Theoretical pI: Translated: 4.85; Mature: 4.85
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.9 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.9 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MAAKPLAAAAIAQLESDGVATLIGTVVNPAGLTHAKTVPLRRMGTFADPGLGASPVWHAF CCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEE TIDQAGIVFGDAISVVGDQRIRIDLGALRILGDGLAWAPGGFFDQTGGPDPYCSRGALRR EECCCCEEECCHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH VEDRLAAAGLTASVGHEMEFVLVAPDGSRLPSTLWAQYGLAGVLEYEGFVRDVTDAANSS HHHHHHHHCCHHHCCCCEEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCC GVPIEQFHPEYGANQFEISLPPMPPVDAADLLVLMRIIVGRVARRHGLRVSLSPVPFAGS CCCHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC VGNGAHQHFSLLRDGVPLFSDGSGAHGMTAEGESAVAGLVAGLPEAQGVLCGSLLSGLRM CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCC QPGHWSGAYICWGTENREAAVRFLQGCQGNVYGGNVEVKVIDPSANPYLATAAVLGLALD CCCCCCCEEEEECCCCHHHHHHHHHCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHC GVEREATLPPETGVDPASLTEAQRTQAGTVLLPARQLDALRALEGSATMRRILGDEVVDA CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHH VVAVRRYEAEHFGALSPEEQADKFRMAWSL HHHHHHHHHHHCCCCCCHHHHHHHHHCCCC >Mature Secondary Structure AAKPLAAAAIAQLESDGVATLIGTVVNPAGLTHAKTVPLRRMGTFADPGLGASPVWHAF CCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCEEEE TIDQAGIVFGDAISVVGDQRIRIDLGALRILGDGLAWAPGGFFDQTGGPDPYCSRGALRR EECCCCEEECCHHHHCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHH VEDRLAAAGLTASVGHEMEFVLVAPDGSRLPSTLWAQYGLAGVLEYEGFVRDVTDAANSS HHHHHHHHCCHHHCCCCEEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCC GVPIEQFHPEYGANQFEISLPPMPPVDAADLLVLMRIIVGRVARRHGLRVSLSPVPFAGS CCCHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCC VGNGAHQHFSLLRDGVPLFSDGSGAHGMTAEGESAVAGLVAGLPEAQGVLCGSLLSGLRM CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCC QPGHWSGAYICWGTENREAAVRFLQGCQGNVYGGNVEVKVIDPSANPYLATAAVLGLALD CCCCCCCEEEEECCCCHHHHHHHHHCCCCCEECCEEEEEEECCCCCCHHHHHHHHHHHHC GVEREATLPPETGVDPASLTEAQRTQAGTVLLPARQLDALRALEGSATMRRILGDEVVDA CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECHHHHHHHHHHCCHHHHHHHHHHHHHHH VVAVRRYEAEHFGALSPEEQADKFRMAWSL HHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2572584 [H]