| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
Click here to switch to the map view.
The map label for this gene is gdhII [H]
Identifier: 108799620
GI number: 108799620
Start: 2805159
End: 2805911
Strand: Reverse
Name: gdhII [H]
Synonym: Mmcs_2653
Alternate gene names: 108799620
Gene position: 2805911-2805159 (Counterclockwise)
Preceding gene: 108799622
Following gene: 108799619
Centisome position: 49.18
GC content: 67.6
Gene sequence:
>753_bases GTGAGCGGAATTCACATCACCAACGATCTTCAGGGCAAGGTCGCGATCGTCACCGGCGCCGCCAGCGGCATCGGGCGGGC GACGACCCTGCTCTTCGCCGAGTACGGCATGTGTGTCGTCGCCGAGGACGTCAACCCCGACGTCGAGCAGCAGTACGCCG ACGTCGAATCGGTGGTGCCCCTGGTCGGCGATGTGGGGGAGGAGCAGACCGCGCTGGACGCGGTCGCCCTGGCCGACCGC GCATTCGGCCGGCTCGACGTGCTCGTCAACAATGCCGGCACCATCGTCAACAGACCGGTCGTCGACACCACACTGGACGA CTGGAACCGCATCCTGACCACCAACGTGACCGGGGCCTTCCTGCGCACCCGCGAGGCGCTGAAGGCGATGATTCCCCGGG CGAAGGGGTCGATCGTCAACATCGGTTCCTACGCGTGTTTCCAGGCGTTCCCGACCATCTCGGCGTACGCGGCCTCGAAG GGGGCCCTGGCGCAGCTGACGCGGACCGCCGCGTTGGAGGGAATCGACCACGGCATCCGGGTCAATGCGATCGGGGTGGG CGATACCGTGACCAACATCCTCGGCGATCCGAACGATCTGGCCGAGCACGGGAAGGGGGCACCCATCGGGCGTGCGGCCG ATCCCCGCGAGATCGCCAATGCGGTCGCATTCCTGGCCTCCGATCTGGCGAGCTACGCCGTCGGCGCGGTGTGGATGCTC GACGGGGGCATGAGCGTTGCGGTGCCGAACTGA
Upstream 100 bases:
>100_bases CGACGGCCGCCCTTCGGTGATGTTTGGGTGCCGCCCCCGCGTGCAACCCCCATCGCAACGATACGTATCGTATCGTTAGT AGAATGAGAGGAGAGGTTCA
Downstream 100 bases:
>100_bases TCGAGGGGACGATGACGAAATCCGACGGCGTCGACACCGCGGCACGTCCGCGCGGTGCGGTGGTGACCGGTTCCATCCTG TCCGCCGCCCGTGACCTGAT
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: GLCDH-II [H]
Number of amino acids: Translated: 250; Mature: 249
Protein sequence:
>250_residues MSGIHITNDLQGKVAIVTGAASGIGRATTLLFAEYGMCVVAEDVNPDVEQQYADVESVVPLVGDVGEEQTALDAVALADR AFGRLDVLVNNAGTIVNRPVVDTTLDDWNRILTTNVTGAFLRTREALKAMIPRAKGSIVNIGSYACFQAFPTISAYAASK GALAQLTRTAALEGIDHGIRVNAIGVGDTVTNILGDPNDLAEHGKGAPIGRAADPREIANAVAFLASDLASYAVGAVWML DGGMSVAVPN
Sequences:
>Translated_250_residues MSGIHITNDLQGKVAIVTGAASGIGRATTLLFAEYGMCVVAEDVNPDVEQQYADVESVVPLVGDVGEEQTALDAVALADR AFGRLDVLVNNAGTIVNRPVVDTTLDDWNRILTTNVTGAFLRTREALKAMIPRAKGSIVNIGSYACFQAFPTISAYAASK GALAQLTRTAALEGIDHGIRVNAIGVGDTVTNILGDPNDLAEHGKGAPIGRAADPREIANAVAFLASDLASYAVGAVWML DGGMSVAVPN >Mature_249_residues SGIHITNDLQGKVAIVTGAASGIGRATTLLFAEYGMCVVAEDVNPDVEQQYADVESVVPLVGDVGEEQTALDAVALADRA FGRLDVLVNNAGTIVNRPVVDTTLDDWNRILTTNVTGAFLRTREALKAMIPRAKGSIVNIGSYACFQAFPTISAYAASKG ALAQLTRTAALEGIDHGIRVNAIGVGDTVTNILGDPNDLAEHGKGAPIGRAADPREIANAVAFLASDLASYAVGAVWMLD GGMSVAVPN
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=238, Percent_Identity=32.7731092436975, Blast_Score=102, Evalue=4e-22, Organism=Homo sapiens, GI15277342, Length=262, Percent_Identity=31.2977099236641, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=29.4605809128631, Blast_Score=98, Evalue=8e-21, Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=33.0708661417323, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI19923817, Length=253, Percent_Identity=30.0395256916996, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI10190704, Length=252, Percent_Identity=29.3650793650794, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI4504505, Length=248, Percent_Identity=30.241935483871, Blast_Score=86, Evalue=5e-17, Organism=Homo sapiens, GI59889578, Length=204, Percent_Identity=31.8627450980392, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=32.4, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=29.4117647058824, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=34.4262295081967, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI31542939, Length=195, Percent_Identity=34.3589743589744, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=30.7692307692308, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4758504, Length=255, Percent_Identity=31.3725490196078, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=34.375, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI210032110, Length=181, Percent_Identity=27.0718232044199, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI7706318, Length=202, Percent_Identity=31.1881188118812, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI226371731, Length=200, Percent_Identity=29.5, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI83715985, Length=173, Percent_Identity=33.5260115606936, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=35.2, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI87082100, Length=252, Percent_Identity=34.5238095238095, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=31.8548387096774, Blast_Score=117, Evalue=9e-28, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=33.1967213114754, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1789208, Length=246, Percent_Identity=33.3333333333333, Blast_Score=111, Evalue=5e-26, Organism=Escherichia coli, GI2367175, Length=249, Percent_Identity=35.3413654618474, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=32.258064516129, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1786812, Length=253, Percent_Identity=33.201581027668, Blast_Score=103, Evalue=1e-23, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=31.9838056680162, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=34.0080971659919, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=27.843137254902, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI2367365, Length=238, Percent_Identity=31.0924369747899, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1787820, Length=157, Percent_Identity=28.6624203821656, Blast_Score=65, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=36.3636363636364, Blast_Score=134, Evalue=6e-32, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=33.969465648855, Blast_Score=130, Evalue=6e-31, Organism=Caenorhabditis elegans, GI17531453, Length=264, Percent_Identity=33.7121212121212, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI17562908, Length=264, Percent_Identity=34.469696969697, Blast_Score=121, Evalue=4e-28, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=32.9365079365079, Blast_Score=120, Evalue=7e-28, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=30.3030303030303, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=31.25, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=30.5343511450382, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=32.5757575757576, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=33.2046332046332, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560150, Length=262, Percent_Identity=30.9160305343511, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=33.4586466165414, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=33.210332103321, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17563726, Length=261, Percent_Identity=32.5670498084291, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI25147288, Length=245, Percent_Identity=31.4285714285714, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562910, Length=265, Percent_Identity=30.9433962264151, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17560332, Length=260, Percent_Identity=31.5384615384615, Blast_Score=103, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=31.0606060606061, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=32.7935222672065, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=29.7619047619048, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=28.735632183908, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=31.0756972111554, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=30.9236947791165, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=30.9236947791165, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17565030, Length=265, Percent_Identity=31.3207547169811, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17568967, Length=186, Percent_Identity=32.258064516129, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=28.4090909090909, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=30.0813008130081, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17561272, Length=251, Percent_Identity=29.4820717131474, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17559552, Length=213, Percent_Identity=28.169014084507, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI212645366, Length=125, Percent_Identity=37.6, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17557668, Length=213, Percent_Identity=27.6995305164319, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI17564282, Length=166, Percent_Identity=27.710843373494, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322067, Length=223, Percent_Identity=34.0807174887892, Blast_Score=76, Evalue=5e-15, Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=30, Blast_Score=68, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=188, Percent_Identity=25.531914893617, Blast_Score=67, Evalue=2e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=250, Percent_Identity=25.2, Blast_Score=62, Evalue=8e-11, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=36.078431372549, Blast_Score=144, Evalue=5e-35, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=36.6533864541833, Blast_Score=132, Evalue=2e-31, Organism=Drosophila melanogaster, GI28571526, Length=256, Percent_Identity=35.546875, Blast_Score=124, Evalue=8e-29, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=34.1176470588235, Blast_Score=122, Evalue=2e-28, Organism=Drosophila melanogaster, GI24644337, Length=262, Percent_Identity=34.3511450381679, Blast_Score=108, Evalue=3e-24, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=35.655737704918, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=33.6032388663968, Blast_Score=103, Evalue=9e-23, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=32.9317269076305, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=35.2631578947368, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24584748, Length=198, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI161076933, Length=198, Percent_Identity=30.3030303030303, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24584744, Length=198, Percent_Identity=30.8080808080808, Blast_Score=77, Evalue=7e-15, Organism=Drosophila melanogaster, GI28574402, Length=198, Percent_Identity=30.8080808080808, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=30.7392996108949, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI116007236, Length=231, Percent_Identity=29.8701298701299, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24648693, Length=236, Percent_Identity=32.2033898305085, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21355889, Length=236, Percent_Identity=32.2033898305085, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI28571387, Length=201, Percent_Identity=30.3482587064677, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24641232, Length=228, Percent_Identity=30.7017543859649, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21355631, Length=159, Percent_Identity=29.559748427673, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007238, Length=210, Percent_Identity=29.5238095238095, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI281364892, Length=230, Percent_Identity=26.0869565217391, Blast_Score=64, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.47 [H]
Molecular weight: Translated: 25906; Mature: 25774
Theoretical pI: Translated: 4.38; Mature: 4.38
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSGIHITNDLQGKVAIVTGAASGIGRATTLLFAEYGMCVVAEDVNPDVEQQYADVESVVP CCCCEECCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHH LVGDVGEEQTALDAVALADRAFGRLDVLVNNAGTIVNRPVVDTTLDDWNRILTTNVTGAF HHHCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEECCCCCCCHHHHHHEEECCCHHHH LRTREALKAMIPRAKGSIVNIGSYACFQAFPTISAYAASKGALAQLTRTAALEGIDHGIR HHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEE VNAIGVGDTVTNILGDPNDLAEHGKGAPIGRAADPREIANAVAFLASDLASYAVGAVWML EEEEECCHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEE DGGMSVAVPN CCCEEEECCC >Mature Secondary Structure SGIHITNDLQGKVAIVTGAASGIGRATTLLFAEYGMCVVAEDVNPDVEQQYADVESVVP CCCEECCCCCCEEEEEEECCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHH LVGDVGEEQTALDAVALADRAFGRLDVLVNNAGTIVNRPVVDTTLDDWNRILTTNVTGAF HHHCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCEEECCCCCCCHHHHHHEEECCCHHHH LRTREALKAMIPRAKGSIVNIGSYACFQAFPTISAYAASKGALAQLTRTAALEGIDHGIR HHHHHHHHHHCCCCCCCEEEECCHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEE VNAIGVGDTVTNILGDPNDLAEHGKGAPIGRAADPREIANAVAFLASDLASYAVGAVWML EEEEECCHHHHHHCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEE DGGMSVAVPN CCCEEEECCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA