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The map label for this gene is nhaA2 [H]

Identifier: 108798439

GI number: 108798439

Start: 1598489

End: 1599430

Strand: Reverse

Name: nhaA2 [H]

Synonym: Mmcs_1468

Alternate gene names: 108798439

Gene position: 1599430-1598489 (Counterclockwise)

Preceding gene: 108798443

Following gene: 108798438

Centisome position: 28.03

GC content: 62.31

Gene sequence:

>942_bases
ATGATGCGACACCAAACCCTGCGAGAGGCCGATCACCCAGGCCATGTCGCACACGCACAGTTCATCGCCGGCCGCCAACG
CCGCGGCGATCGACAACCGGGTGGCATCACTCAAGCCGCGGGCGGCCGCGGCCGCGGCAGCCACCGTGTCGCTATCTGGC
ACCGTGGCCCTGATCTGCTCCGCGTGGGGCAGGTCCAAACACAGCAGATCGCAGGTATCCAGCGGCTCACTCATATCCAT
ATACTAAAGTACGTTGATATGAAAACGAAAGGCCTCAGCTCGATTCTGGCCAACACCCGCGTGCTCCTCACGATCTTCGT
CATCGCGGTCGCCACCGTCGCCACCGCGGTCTTTCTCTCCGTGCGCGACAGCGGCTCGGCGGCCGAGGTTGCACTCGACG
GGTCGCTAGCCGGCCAAACAGTCCGAGACAACAGTCACCGGCTGAACTCGGTACCTGACAGCGATGTCTACTTCGTCGAG
TTCCTCGACTTCGAATGCGAAGGCTGCCGCGCGCTCTACCCGGTCGTCGAGCAGCTGCGCGCCGAGTACGGCGACCGGGT
GAACTTCGTACTGCGCTACTTCCCGCTACGATCCCACTTCAACGCCGAACGCGCCGCCCGCGCTGTCGAAGCCGCAGCCC
AACAAGGCCAACTCGAAGCGATGTACAAGAAAATGTATGAGACACAAGCCCAGTGGGGTGAACAGCAGGTTCCGGCCGAT
GATGTGTTCCGCGGATTCGCCCAACAACTTGGCCTCGACATGAGCACCTTTGACGCCACCTACAACGACCCCGCAACCCT
GGAACGCATCCAGCTCGACATCAGCGACGGCACCGCACTCGGTGTCCAAGGCACCCCCACCTTCTTCATCAACGACGAAC
GCATCCAGCCCCGCAGCTACGAAGACCTCACCACAGCACTTGATCAGGCTCTCGCGCGCTGA

Upstream 100 bases:

>100_bases
CCGCGGCCGTCAACTGGCGTCCGCGCTCGGTCAGCCGGTACATCACCAACTTGCCCTGCCTGCGCGAGGACACCAGGGAG
GCGTTCTTGAGCTGGCGCAG

Downstream 100 bases:

>100_bases
TGCCGCCGTCCGCACATGCGGATCGACGGCCGGTAACAGGCAATCGACAGTGCCCCACGAGCGTGGGCGCTTCGCTGATC
AGCAAGATCGAGAACGGCTG

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MMRHQTLREADHPGHVAHAQFIAGRQRRGDRQPGGITQAAGGRGRGSHRVAIWHRGPDLLRVGQVQTQQIAGIQRLTHIH
ILKYVDMKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVE
FLDFECEGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPAD
DVFRGFAQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR

Sequences:

>Translated_313_residues
MMRHQTLREADHPGHVAHAQFIAGRQRRGDRQPGGITQAAGGRGRGSHRVAIWHRGPDLLRVGQVQTQQIAGIQRLTHIH
ILKYVDMKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVE
FLDFECEGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPAD
DVFRGFAQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR
>Mature_313_residues
MMRHQTLREADHPGHVAHAQFIAGRQRRGDRQPGGITQAAGGRGRGSHRVAIWHRGPDLLRVGQVQTQQIAGIQRLTHIH
ILKYVDMKTKGLSSILANTRVLLTIFVIAVATVATAVFLSVRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVE
FLDFECEGCRALYPVVEQLRAEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPAD
DVFRGFAQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSYEDLTTALDQALAR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 34770; Mature: 34770

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRHQTLREADHPGHVAHAQFIAGRQRRGDRQPGGITQAAGGRGRGSHRVAIWHRGPDLL
CCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCE
RVGQVQTQQIAGIQRLTHIHILKYVDMKTKGLSSILANTRVLLTIFVIAVATVATAVFLS
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVEFLDFECEGCRALYPVVEQLR
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
AEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPAD
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHH
DVFRGFAQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSY
HHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEEEECCCEEECCCCCCEEEEECCCCCCCCH
EDLTTALDQALAR
HHHHHHHHHHHCC
>Mature Secondary Structure
MMRHQTLREADHPGHVAHAQFIAGRQRRGDRQPGGITQAAGGRGRGSHRVAIWHRGPDLL
CCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCE
RVGQVQTQQIAGIQRLTHIHILKYVDMKTKGLSSILANTRVLLTIFVIAVATVATAVFLS
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VRDSGSAAEVALDGSLAGQTVRDNSHRLNSVPDSDVYFVEFLDFECEGCRALYPVVEQLR
CCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
AEYGDRVNFVLRYFPLRSHFNAERAARAVEAAAQQGQLEAMYKKMYETQAQWGEQQVPAD
HHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHH
DVFRGFAQQLGLDMSTFDATYNDPATLERIQLDISDGTALGVQGTPTFFINDERIQPRSY
HHHHHHHHHHCCCHHHCCCCCCCCCCEEEEEEEECCCEEECCCCCCEEEEECCCCCCCCH
EDLTTALDQALAR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA