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The map label for this gene is glpD2 [H]

Identifier: 108798221

GI number: 108798221

Start: 1353510

End: 1355249

Strand: Direct

Name: glpD2 [H]

Synonym: Mmcs_1250

Alternate gene names: 108798221

Gene position: 1353510-1355249 (Clockwise)

Preceding gene: 108798220

Following gene: 108798222

Centisome position: 23.72

GC content: 69.43

Gene sequence:

>1740_bases
GTGAGTGACCCGATCGCAGGTAACGGGCAGACTTTGCTCGGGCCCGACCAGCGGGCCGAGGCCTGGCGGCGGCTCGGCAG
CGAGCAGTTCGACGTCGTGGTGATCGGCGGGGGTGTGGTCGGAGCCGGCGCCGCCCTCGACGCCGCCACCCGTGGACTCA
AGGTCGCCCTGGTGGAGGCGCGCGACTTCGCCTCGGGGACGTCCAGCCGCAGCAGCAAGATGTTCCACGGCGGTCTGCGC
TACCTCGAACAGCTCGAGTTCGGGCTGGTCCGCGAGGCGCTGCACGAACGCGAGCTGTCGCTGACCACGCTGGCGCCGCA
TCTGGTCAAACCGCTGCCCTTCCTGTTCCCGCTGACCAACCGCTGGTGGGAGCGGCCCTACGTGGCGGCGGGCATCTTCC
TCTACGACCAGCTCGGCGGTGCGAAATCCGTTCCCGCGCAGCGGCATCTGACCAAGTCCGGGGCGTTGCGGCTGGCGCCC
GGACTCAAACGCAGCTCGTTGATCGGCGGCATCCGCTACTTCGACACCGTCGTCGACGACGCGCGGCACACCATGATGGT
CGCCCGGACGGCGGCGCACTACGGCGCGGTGGTGCGCACGTCGACGCAGGTGGTCAACCTGCTGCGGGAAGGCGACCGGG
TGATCGGTGTCGCCGTGCGCGACAGCGAGGACGGGTCGGTCACCGACGTCCACGGCCACGTCGTGGTCAACGCCACCGGC
GTGTGGACCGACGAGATCCAGGCGCTGTCACGGCAACGCGGCCGGTTCCGGGTGCGCGCATCCAAGGGTGTGCACATCGT
GGTGCCCCGCGATCGGATCGTCAGCGAGGTCGCGATCATCCTGCGCACCGAGAAGTCCGTGCTGTTCGTCATCCCGTGGG
GGACGCACTGGATCATCGGCACCACCGACACCGACTGGAATCTCGACCTGGCGCATCCGGCCGCGACCAAGGCCGACATC
GACTACATCCTCGACCACGTCAACACCGTGCTGGCCACGCCGCTCACCCACGACGACATCGACGGCGTCTACGCCGGGCT
GCGTCCGCTGCTGGCGGGGGAGAGCGAGGAGACCTCGAAACTGTCCCGTGAGCACGCCGTCGCAAGCCCGGCGCCGGGGC
TGGTCGCGATCGCCGGCGGCAAGTACACCACCTACCGGGTGATGGGTGAGGATGCGATCGACGCGGCCGCCGAGTTCGTC
CCCGCCCGCGTGGCGCCGTCGATCACCGAGAAGGTGCCGCTGATGGGGGCCGACGGATACTTCGCGCTGATCAACCAGAC
CCAGAGTGTCGGCGCCCATTACGGTTTGCACCCGTATAGGGTGCGTCACCTGCTCGACCGGTACGGCTCGCTGATCACCG
AGGTGCTGGCATTTGCCGATGGCAGGCCCGAACTTCTCACCCCGATCACCGCGGCGCCCGTCTACCTCAAGGTGGAGGCC
GCGTACGCCGCGGCCGCCGAGGGGGCGCTGCACCTCGAGGACATCCTGGCCCGCCGGATGCGCATCTCGATCGAGTATCC
GCACCGCGGCGTCGACTGTGCCCGTGAGGTCGCCGAAGTCGTTGCGCCCATTCTGGGTTGGAGCGCCGAGGACGTCAGCC
GCGAGGTGGACACGTACTGTGCGCGTGTCGACGCCGAGGTGCGCAGCCAGCAGCAACCCGACGACGAGTCCGCCGATGCG
CTGCGCGCGGCGGCGCCCGAGGCCAGGGCGGAGATCCTCGAACCCGTCCCGTTGCGATGA

Upstream 100 bases:

>100_bases
GTTCGATCGTGGAGGCCGCGCGTCGGCTCATGGCGCACGACGATCTGGACTGAACCCCGCGGACGCGAGGAGCAAAGGAA
AAGCACGTAGCCTGGGAACG

Downstream 100 bases:

>100_bases
GCCGGGTGCGGCCCGCGCCACTTCCGGTGCGCGACGGGCTCGGACCGGCCCGGGTGCGGCTGCGCGGCGGTGCGGTGCTG
GTCGAGCTGGCCGACCGCTT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSDPIAGNGQTLLGPDQRAEAWRRLGSEQFDVVVIGGGVVGAGAALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLR
YLEQLEFGLVREALHERELSLTTLAPHLVKPLPFLFPLTNRWWERPYVAAGIFLYDQLGGAKSVPAQRHLTKSGALRLAP
GLKRSSLIGGIRYFDTVVDDARHTMMVARTAAHYGAVVRTSTQVVNLLREGDRVIGVAVRDSEDGSVTDVHGHVVVNATG
VWTDEIQALSRQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWGTHWIIGTTDTDWNLDLAHPAATKADI
DYILDHVNTVLATPLTHDDIDGVYAGLRPLLAGESEETSKLSREHAVASPAPGLVAIAGGKYTTYRVMGEDAIDAAAEFV
PARVAPSITEKVPLMGADGYFALINQTQSVGAHYGLHPYRVRHLLDRYGSLITEVLAFADGRPELLTPITAAPVYLKVEA
AYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPILGWSAEDVSREVDTYCARVDAEVRSQQQPDDESADA
LRAAAPEARAEILEPVPLR

Sequences:

>Translated_579_residues
MSDPIAGNGQTLLGPDQRAEAWRRLGSEQFDVVVIGGGVVGAGAALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLR
YLEQLEFGLVREALHERELSLTTLAPHLVKPLPFLFPLTNRWWERPYVAAGIFLYDQLGGAKSVPAQRHLTKSGALRLAP
GLKRSSLIGGIRYFDTVVDDARHTMMVARTAAHYGAVVRTSTQVVNLLREGDRVIGVAVRDSEDGSVTDVHGHVVVNATG
VWTDEIQALSRQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWGTHWIIGTTDTDWNLDLAHPAATKADI
DYILDHVNTVLATPLTHDDIDGVYAGLRPLLAGESEETSKLSREHAVASPAPGLVAIAGGKYTTYRVMGEDAIDAAAEFV
PARVAPSITEKVPLMGADGYFALINQTQSVGAHYGLHPYRVRHLLDRYGSLITEVLAFADGRPELLTPITAAPVYLKVEA
AYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPILGWSAEDVSREVDTYCARVDAEVRSQQQPDDESADA
LRAAAPEARAEILEPVPLR
>Mature_578_residues
SDPIAGNGQTLLGPDQRAEAWRRLGSEQFDVVVIGGGVVGAGAALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRY
LEQLEFGLVREALHERELSLTTLAPHLVKPLPFLFPLTNRWWERPYVAAGIFLYDQLGGAKSVPAQRHLTKSGALRLAPG
LKRSSLIGGIRYFDTVVDDARHTMMVARTAAHYGAVVRTSTQVVNLLREGDRVIGVAVRDSEDGSVTDVHGHVVVNATGV
WTDEIQALSRQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWGTHWIIGTTDTDWNLDLAHPAATKADID
YILDHVNTVLATPLTHDDIDGVYAGLRPLLAGESEETSKLSREHAVASPAPGLVAIAGGKYTTYRVMGEDAIDAAAEFVP
ARVAPSITEKVPLMGADGYFALINQTQSVGAHYGLHPYRVRHLLDRYGSLITEVLAFADGRPELLTPITAAPVYLKVEAA
YAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPILGWSAEDVSREVDTYCARVDAEVRSQQQPDDESADAL
RAAAPEARAEILEPVPLR

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=551, Percent_Identity=34.8457350272232, Blast_Score=296, Evalue=3e-80,
Organism=Homo sapiens, GI285002231, Length=551, Percent_Identity=34.8457350272232, Blast_Score=296, Evalue=3e-80,
Organism=Escherichia coli, GI2367226, Length=409, Percent_Identity=35.2078239608802, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1788574, Length=380, Percent_Identity=30.7894736842105, Blast_Score=123, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17509253, Length=544, Percent_Identity=34.7426470588235, Blast_Score=248, Evalue=8e-66,
Organism=Caenorhabditis elegans, GI115534726, Length=524, Percent_Identity=32.6335877862595, Blast_Score=244, Evalue=8e-65,
Organism=Saccharomyces cerevisiae, GI6322036, Length=588, Percent_Identity=31.4625850340136, Blast_Score=225, Evalue=2e-59,
Organism=Drosophila melanogaster, GI161077125, Length=558, Percent_Identity=36.0215053763441, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24653942, Length=558, Percent_Identity=36.0215053763441, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24653944, Length=558, Percent_Identity=36.0215053763441, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI20130025, Length=558, Percent_Identity=36.0215053763441, Blast_Score=266, Evalue=3e-71,
Organism=Drosophila melanogaster, GI24586295, Length=539, Percent_Identity=32.0964749536178, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI19921278, Length=545, Percent_Identity=28.0733944954128, Blast_Score=169, Evalue=6e-42,
Organism=Drosophila melanogaster, GI45550977, Length=394, Percent_Identity=24.3654822335025, Blast_Score=102, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62821; Mature: 62690

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPIAGNGQTLLGPDQRAEAWRRLGSEQFDVVVIGGGVVGAGAALDAATRGLKVALVEA
CCCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEEECCCEECCCHHHHHHHCCEEEEEEEC
RDFASGTSSRSSKMFHGGLRYLEQLEFGLVREALHERELSLTTLAPHLVKPLPFLFPLTN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHH
RWWERPYVAAGIFLYDQLGGAKSVPAQRHLTKSGALRLAPGLKRSSLIGGIRYFDTVVDD
HHHCCCHHHHHEEEEHHCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHH
ARHTMMVARTAAHYGAVVRTSTQVVNLLREGDRVIGVAVRDSEDGSVTDVHGHVVVNATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECCEEEEEECC
VWTDEIQALSRQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWGTHWIIG
CCHHHHHHHHHCCCCEEEEECCCEEEEECCHHHHHHHHHEEEECCCEEEEEECCCEEEEE
TTDTDWNLDLAHPAATKADIDYILDHVNTVLATPLTHDDIDGVYAGLRPLLAGESEETSK
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
LSREHAVASPAPGLVAIAGGKYTTYRVMGEDAIDAAAEFVPARVAPSITEKVPLMGADGY
HHHHHCCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCE
FALINQTQSVGAHYGLHPYRVRHLLDRYGSLITEVLAFADGRPELLTPITAAPVYLKVEA
EEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEE
AYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPILGWSAEDVSREVDTYC
HHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARVDAEVRSQQQPDDESADALRAAAPEARAEILEPVPLR
HHHCHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
SDPIAGNGQTLLGPDQRAEAWRRLGSEQFDVVVIGGGVVGAGAALDAATRGLKVALVEA
CCCCCCCCCEECCCHHHHHHHHHCCCCCEEEEEECCCEECCCHHHHHHHCCEEEEEEEC
RDFASGTSSRSSKMFHGGLRYLEQLEFGLVREALHERELSLTTLAPHLVKPLPFLFPLTN
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHH
RWWERPYVAAGIFLYDQLGGAKSVPAQRHLTKSGALRLAPGLKRSSLIGGIRYFDTVVDD
HHHCCCHHHHHEEEEHHCCCCCCCCHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHHHHH
ARHTMMVARTAAHYGAVVRTSTQVVNLLREGDRVIGVAVRDSEDGSVTDVHGHVVVNATG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECCEEEEEECC
VWTDEIQALSRQRGRFRVRASKGVHIVVPRDRIVSEVAIILRTEKSVLFVIPWGTHWIIG
CCHHHHHHHHHCCCCEEEEECCCEEEEECCHHHHHHHHHEEEECCCEEEEEECCCEEEEE
TTDTDWNLDLAHPAATKADIDYILDHVNTVLATPLTHDDIDGVYAGLRPLLAGESEETSK
CCCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCHHHHH
LSREHAVASPAPGLVAIAGGKYTTYRVMGEDAIDAAAEFVPARVAPSITEKVPLMGADGY
HHHHHCCCCCCCCEEEEECCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHCCCCCCCCCE
FALINQTQSVGAHYGLHPYRVRHLLDRYGSLITEVLAFADGRPELLTPITAAPVYLKVEA
EEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEE
AYAAAAEGALHLEDILARRMRISIEYPHRGVDCAREVAEVVAPILGWSAEDVSREVDTYC
HHHHHHCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
ARVDAEVRSQQQPDDESADALRAAAPEARAEILEPVPLR
HHHCHHHHHCCCCCCHHHHHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]