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The map label for this gene is cdd [H]

Identifier: 108798202

GI number: 108798202

Start: 1329607

End: 1330083

Strand: Direct

Name: cdd [H]

Synonym: Mmcs_1231

Alternate gene names: 108798202

Gene position: 1329607-1330083 (Clockwise)

Preceding gene: 108798197

Following gene: 108798203

Centisome position: 23.3

GC content: 66.46

Gene sequence:

>477_bases
GTGCGGGGTCATCCGGGGCGGTCTTCGGAATCCATTCAGAGGCGGGGTGAAAGAGCGCAAATGTCTCCCGAAATCAAGTG
GGAAGTGTTGCGGCGCAAGGCAATTGAGGCATCTACGCTGGCGTATGCGCCCTACTCGGGGTTTCCGGTGGGCGCGGCGG
CGCTCGTCGACGATGACCGAATCGTGACCGGATGCAATGTGGAGAATGTCTCATATGGCCTGGGTCTCTGTGCCGAGTGC
AGTGTGGTCTGCGCCCTGCATTCCGGCGGCGGCGGACGCCTGGTCGCGCTGTCGTGTGTGGGGCCCGATTCCGAGGTGCT
GATGCCCTGTGGCCGGTGCCGTCAGGTGCTGCTCGAACACGGCGGTCCCGATCTGCTGATCGACCATCCGCACGGTCCGC
GGCCGCTCGGGGAACTCCTGCCCGACGCGTTCGGACCCGACGATCTGGCGCGGCGGGCGGCGGGGGAGAAGCCGTGA

Upstream 100 bases:

>100_bases
AAACCTCGGGGCGACTCTAATCCCCTTTGTACTGCCGAACGAACTAGCGTGTTGCCGTAAGCCCCGCTCAGAGGGCAGAA
GTTAGGGTCGCCTATCTGTC

Downstream 100 bases:

>100_bases
CGGACTTCACTTTCGACGCGCCCCGGCCGATGTCGCATCTCGATGCTCCGACCGTCATCCGGGTCAAACGCGACGGCGGC
GACCTGCCCGACGAGGCGAT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MRGHPGRSSESIQRRGERAQMSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAEC
SVVCALHSGGGGRLVALSCVGPDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP

Sequences:

>Translated_158_residues
MRGHPGRSSESIQRRGERAQMSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAEC
SVVCALHSGGGGRLVALSCVGPDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP
>Mature_158_residues
MRGHPGRSSESIQRRGERAQMSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDRIVTGCNVENVSYGLGLCAEC
SVVCALHSGGGGRLVALSCVGPDSEVLMPCGRCRQVLLEHGGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=121, Percent_Identity=41.3223140495868, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17540514, Length=113, Percent_Identity=43.3628318584071, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17551074, Length=126, Percent_Identity=42.0634920634921, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323274, Length=132, Percent_Identity=38.6363636363636, Blast_Score=84, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24582741, Length=111, Percent_Identity=39.6396396396396, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19920920, Length=100, Percent_Identity=39, Blast_Score=68, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582744, Length=110, Percent_Identity=42.7272727272727, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 16738; Mature: 16738

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGHPGRSSESIQRRGERAQMSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDR
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHEEECCCCCCCCCEEEEECCCE
IVTGCNVENVSYGLGLCAECSVVCALHSGGGGRLVALSCVGPDSEVLMPCGRCRQVLLEH
EEECCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCEECCCHHHHHHHHHC
GGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP
CCCCEEEECCCCCCCHHHHCCCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MRGHPGRSSESIQRRGERAQMSPEIKWEVLRRKAIEASTLAYAPYSGFPVGAAALVDDDR
CCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHCHHHEEECCCCCCCCCEEEEECCCE
IVTGCNVENVSYGLGLCAECSVVCALHSGGGGRLVALSCVGPDSEVLMPCGRCRQVLLEH
EEECCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCEECCCHHHHHHHHHC
GGPDLLIDHPHGPRPLGELLPDAFGPDDLARRAAGEKP
CCCCEEEECCCCCCCHHHHCCCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]