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The map label for this gene is trpS [H]

Identifier: 108798183

GI number: 108798183

Start: 1311591

End: 1312625

Strand: Direct

Name: trpS [H]

Synonym: Mmcs_1212

Alternate gene names: 108798183

Gene position: 1311591-1312625 (Clockwise)

Preceding gene: 108798182

Following gene: 108798184

Centisome position: 22.99

GC content: 66.96

Gene sequence:

>1035_bases
ATGAACTCCCCAGTCGAGACCCCGCCCGCCGTGCCTCGTGTCGTCTTCTCGGGTGTGCAGCCCACCTCCGATTCGCTGCA
CCTGGGCAACGCGCTGGGAGCCGTCACGCACTGGACGGCCCTGCAGGACGACTACGACGCCTACTTCTGCGTCGTCGACC
TGCACGCGATCACCGTGCCGCAGGATCCCGAGACGCTGCGGTACCGCACCCTCGTCACCGCGGCGCAGTATCTGGCGCTG
GGCATCGACCCGGCGCGCAGCACGGTCTTCGTGCAGAGCCATGTGCCCGCCCACACCGAGTTGGCCTGGGTGCTGGGCTG
TTTCACCGGTTTCGGCCAGGCGTCGCGGATGACCCAGTTCAAGGACAAGTCGCAGAAGCAGGGCGCGGACGCCACCACCG
TCGGCCTGTTCACCTACCCGGTGCTGATGGCCGCCGACGTGCTGCTCTACGACACCGATCTGGTGCCCGTCGGTGAGGAT
CAGCGCCAACACCTCGAACTCGCCCGCGACGTCGCCCAGCGGTTCAACGCGCGGTTCCCGGACACGTTCGTCATCCCCGA
GCCGATGATCCCGAAGGCCACCGCGAAGATCTACGACCTGCAGGATCCGACGGCGAAGATGAGCAAGTCGGCGGGAACCG
ACGCGGGCCTGATCACCCTGCTCGACGATCCGAAGAAGACGGCCAAGAAGATCCGCTCGGCGGTCACCGACAGCGAGCGT
GAGATCCGATTCGACCGCGAGCAGAAGGCGGGGGTGTCGAATCTGCTGACGATCCAGGCCGCGGTCACCGGCACCGACGT
CGACGTGCTCGTCGAGGCGTACCAGGGCCGTGGGTACGGCGATCTGAAGAAGGACACCGCCGATGCGGTGGTCGAGTTCG
TCACGCCGATCAAGACCAGGGTCGACGAACTACTGGCCGATCCTGCCGAACTCGAGGGTGTGCTGGCGACGGGCGCCGAA
CGGGCCCGTGACGTGACTGCCAAGACGCTCCAGCGGGTATACGACCGGCTGGGATTGCTGCGCCCGCGGGCATGA

Upstream 100 bases:

>100_bases
CGGGTCGAGCGGGCCGACGCCTACGCGCTGCGCTGGTCGGACCACGCACCGGTCACCGTCGAATACTCGTGACCATCCCG
CGTGGAAAGATCGAGGCATC

Downstream 100 bases:

>100_bases
CGACTGGAGGCTGGTATGGACGAACCGGCCGAGCCGGGAAAGCTGGACCGGCTGCGCGCCCGATACGGCTGGTTCGACCA
CGTCATGCGGGCGCAGGAGC

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MNSPVETPPAVPRVVFSGVQPTSDSLHLGNALGAVTHWTALQDDYDAYFCVVDLHAITVPQDPETLRYRTLVTAAQYLAL
GIDPARSTVFVQSHVPAHTELAWVLGCFTGFGQASRMTQFKDKSQKQGADATTVGLFTYPVLMAADVLLYDTDLVPVGED
QRQHLELARDVAQRFNARFPDTFVIPEPMIPKATAKIYDLQDPTAKMSKSAGTDAGLITLLDDPKKTAKKIRSAVTDSER
EIRFDREQKAGVSNLLTIQAAVTGTDVDVLVEAYQGRGYGDLKKDTADAVVEFVTPIKTRVDELLADPAELEGVLATGAE
RARDVTAKTLQRVYDRLGLLRPRA

Sequences:

>Translated_344_residues
MNSPVETPPAVPRVVFSGVQPTSDSLHLGNALGAVTHWTALQDDYDAYFCVVDLHAITVPQDPETLRYRTLVTAAQYLAL
GIDPARSTVFVQSHVPAHTELAWVLGCFTGFGQASRMTQFKDKSQKQGADATTVGLFTYPVLMAADVLLYDTDLVPVGED
QRQHLELARDVAQRFNARFPDTFVIPEPMIPKATAKIYDLQDPTAKMSKSAGTDAGLITLLDDPKKTAKKIRSAVTDSER
EIRFDREQKAGVSNLLTIQAAVTGTDVDVLVEAYQGRGYGDLKKDTADAVVEFVTPIKTRVDELLADPAELEGVLATGAE
RARDVTAKTLQRVYDRLGLLRPRA
>Mature_344_residues
MNSPVETPPAVPRVVFSGVQPTSDSLHLGNALGAVTHWTALQDDYDAYFCVVDLHAITVPQDPETLRYRTLVTAAQYLAL
GIDPARSTVFVQSHVPAHTELAWVLGCFTGFGQASRMTQFKDKSQKQGADATTVGLFTYPVLMAADVLLYDTDLVPVGED
QRQHLELARDVAQRFNARFPDTFVIPEPMIPKATAKIYDLQDPTAKMSKSAGTDAGLITLLDDPKKTAKKIRSAVTDSER
EIRFDREQKAGVSNLLTIQAAVTGTDVDVLVEAYQGRGYGDLKKDTADAVVEFVTPIKTRVDELLADPAELEGVLATGAE
RARDVTAKTLQRVYDRLGLLRPRA

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=327, Percent_Identity=44.6483180428135, Blast_Score=276, Evalue=1e-74,
Organism=Homo sapiens, GI41352700, Length=177, Percent_Identity=51.9774011299435, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1789786, Length=329, Percent_Identity=52.5835866261398, Blast_Score=351, Evalue=4e-98,
Organism=Caenorhabditis elegans, GI71982800, Length=335, Percent_Identity=35.5223880597015, Blast_Score=205, Evalue=3e-53,
Organism=Caenorhabditis elegans, GI71982793, Length=335, Percent_Identity=35.5223880597015, Blast_Score=204, Evalue=5e-53,
Organism=Saccharomyces cerevisiae, GI6320474, Length=345, Percent_Identity=38.5507246376812, Blast_Score=221, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24666151, Length=330, Percent_Identity=42.1212121212121, Blast_Score=255, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37587; Mature: 37587

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPVETPPAVPRVVFSGVQPTSDSLHLGNALGAVTHWTALQDDYDAYFCVVDLHAITVP
CCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECC
QDPETLRYRTLVTAAQYLALGIDPARSTVFVQSHVPAHTELAWVLGCFTGFGQASRMTQF
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHH
KDKSQKQGADATTVGLFTYPVLMAADVLLYDTDLVPVGEDQRQHLELARDVAQRFNARFP
HHHHHHCCCCCEEHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
DTFVIPEPMIPKATAKIYDLQDPTAKMSKSAGTDAGLITLLDDPKKTAKKIRSAVTDSER
CCEECCCCCCCCCHHEEEECCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCHH
EIRFDREQKAGVSNLLTIQAAVTGTDVDVLVEAYQGRGYGDLKKDTADAVVEFVTPIKTR
HHCCCCHHHCCHHHEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VDELLADPAELEGVLATGAERARDVTAKTLQRVYDRLGLLRPRA
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNSPVETPPAVPRVVFSGVQPTSDSLHLGNALGAVTHWTALQDDYDAYFCVVDLHAITVP
CCCCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECC
QDPETLRYRTLVTAAQYLALGIDPARSTVFVQSHVPAHTELAWVLGCFTGFGQASRMTQF
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHH
KDKSQKQGADATTVGLFTYPVLMAADVLLYDTDLVPVGEDQRQHLELARDVAQRFNARFP
HHHHHHCCCCCEEHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCC
DTFVIPEPMIPKATAKIYDLQDPTAKMSKSAGTDAGLITLLDDPKKTAKKIRSAVTDSER
CCEECCCCCCCCCHHEEEECCCCHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHCCCHH
EIRFDREQKAGVSNLLTIQAAVTGTDVDVLVEAYQGRGYGDLKKDTADAVVEFVTPIKTR
HHCCCCHHHCCHHHEEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
VDELLADPAELEGVLATGAERARDVTAKTLQRVYDRLGLLRPRA
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]