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The map label for this gene is alr [H]

Identifier: 108798118

GI number: 108798118

Start: 1245646

End: 1246797

Strand: Direct

Name: alr [H]

Synonym: Mmcs_1146

Alternate gene names: 108798118

Gene position: 1245646-1246797 (Clockwise)

Preceding gene: 108798117

Following gene: 108798119

Centisome position: 21.83

GC content: 70.31

Gene sequence:

>1152_bases
ATGCAGACATCCGAGACGACCGTGACCCCCACCGCGCAGGTGGTCGTCGACCTCGACGCGATCTCACACAACGTGGCGCT
TCTGCGTGACCGCGCTGGATCTGCCCAGGTGATGCCGGTGCTCAAGGCCGACGGCTACGGACACGGCGCCACCGAAGTCG
CGAAGGTCGTCCTCGACGCCGGGGTCACCGAACTCGGCGTGGCCACCGTCGGCGAGGCGCTCGCACTGCGCGCCGACGGC
ATCACCGCACCGGTGCTGGCGTGGCTGCACGGCCCGGGCACCGACTTCGCCCCGGCGGTGCAGGCCGACATCCAACTCGC
CGTGTCCTCGGTGCGTCAGCTCGGCGAGATCCTCGACGCCGTCCACCGCACCGGGATGACGGCCACCCTCACCGTGAAGG
CCGACACCGGGCTGAGCCGCAACGGGGTGAGCCCCGCCGAATACCCGGCACTGCTGCAACGCCTGGCCAAGGCGCAAGCC
GAGGACGCGGTGCGGGTACGCGGCATCATGTCGCATCTGGCGTGCGGAGACGAACCCGACAACCCCACCAACGACCGGCA
GGCGCAGCGGTTGACGGACATGCGGCGCCAGGCCGCTGACGCCGGCGTGACGTTCGAGGTCGCGCATCTGTGCAACTCAC
CGGCCGCGATGACCCGACCCGACCTCGCCTTCGACATGGTCCGCCCCGGGATCGCCGTGTATGGGCAGACCCCGATCCCC
GCGCTCGGCGACATGGGTCTGCGTCCCGCGATGACGTTGAGATGTCCGGTCGCGCAGACCCGTTCGATCAAGGCCGGTGA
CGGGGTGTCCTACGGCCACACCTGGATCGCCCAGCGTGACACCACGGTCGCGCTGCTCCCGATCGGCTACGCCGACGGGG
TGTACCGCTCGCTGAGTGGGCGCCTGCAGGTGCTGATCAACGGCCGGCTGCGGCCCGGGGTGGGACGGATCTGCATGGAC
CAGTTCGTCGTCGACCTCGGACCCGGGCCCGTCGACGTCAGCGACGGCGACGAGGCCATCCTGTTCGGCCCCGGGACCCG
CGGCGAACACACCGCCCAGGACTGGGCCGAGATCATCGGCACCATCAACTACGAGATCGTCACCAGCCCCCGCGGCCGGG
TCGTCCGCACCTACCGACGGGAAAGCCGTTGA

Upstream 100 bases:

>100_bases
CCCGCACGCGATCCGCCCCGGCGGCGATCCCCTCCTGGATAACCGGCCGCGCCGCACCTGGCGACCGGGTTCTGGGAGAA
TCGAGCGCGGTGACATGACC

Downstream 100 bases:

>100_bases
TCGACAACGAGAACAGGCGACGTGGAAACGCCGGCTGGCTGGCCGGCGCCGCGGGACTGGCGGCGGTCGGCTCACTGGCC
GGGGTGACCGTGGCCCGCTC

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MQTSETTVTPTAQVVVDLDAISHNVALLRDRAGSAQVMPVLKADGYGHGATEVAKVVLDAGVTELGVATVGEALALRADG
ITAPVLAWLHGPGTDFAPAVQADIQLAVSSVRQLGEILDAVHRTGMTATLTVKADTGLSRNGVSPAEYPALLQRLAKAQA
EDAVRVRGIMSHLACGDEPDNPTNDRQAQRLTDMRRQAADAGVTFEVAHLCNSPAAMTRPDLAFDMVRPGIAVYGQTPIP
ALGDMGLRPAMTLRCPVAQTRSIKAGDGVSYGHTWIAQRDTTVALLPIGYADGVYRSLSGRLQVLINGRLRPGVGRICMD
QFVVDLGPGPVDVSDGDEAILFGPGTRGEHTAQDWAEIIGTINYEIVTSPRGRVVRTYRRESR

Sequences:

>Translated_383_residues
MQTSETTVTPTAQVVVDLDAISHNVALLRDRAGSAQVMPVLKADGYGHGATEVAKVVLDAGVTELGVATVGEALALRADG
ITAPVLAWLHGPGTDFAPAVQADIQLAVSSVRQLGEILDAVHRTGMTATLTVKADTGLSRNGVSPAEYPALLQRLAKAQA
EDAVRVRGIMSHLACGDEPDNPTNDRQAQRLTDMRRQAADAGVTFEVAHLCNSPAAMTRPDLAFDMVRPGIAVYGQTPIP
ALGDMGLRPAMTLRCPVAQTRSIKAGDGVSYGHTWIAQRDTTVALLPIGYADGVYRSLSGRLQVLINGRLRPGVGRICMD
QFVVDLGPGPVDVSDGDEAILFGPGTRGEHTAQDWAEIIGTINYEIVTSPRGRVVRTYRRESR
>Mature_383_residues
MQTSETTVTPTAQVVVDLDAISHNVALLRDRAGSAQVMPVLKADGYGHGATEVAKVVLDAGVTELGVATVGEALALRADG
ITAPVLAWLHGPGTDFAPAVQADIQLAVSSVRQLGEILDAVHRTGMTATLTVKADTGLSRNGVSPAEYPALLQRLAKAQA
EDAVRVRGIMSHLACGDEPDNPTNDRQAQRLTDMRRQAADAGVTFEVAHLCNSPAAMTRPDLAFDMVRPGIAVYGQTPIP
ALGDMGLRPAMTLRCPVAQTRSIKAGDGVSYGHTWIAQRDTTVALLPIGYADGVYRSLSGRLQVLINGRLRPGVGRICMD
QFVVDLGPGPVDVSDGDEAILFGPGTRGEHTAQDWAEIIGTINYEIVTSPRGRVVRTYRRESR

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=378, Percent_Identity=34.9206349206349, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787439, Length=373, Percent_Identity=30.2949061662198, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 40597; Mature: 40597

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSETTVTPTAQVVVDLDAISHNVALLRDRAGSAQVMPVLKADGYGHGATEVAKVVLDA
CCCCCCCCCCCEEEEEEHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHC
GVTELGVATVGEALALRADGITAPVLAWLHGPGTDFAPAVQADIQLAVSSVRQLGEILDA
CCHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHRTGMTATLTVKADTGLSRNGVSPAEYPALLQRLAKAQAEDAVRVRGIMSHLACGDEPD
HHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NPTNDRQAQRLTDMRRQAADAGVTFEVAHLCNSPAAMTRPDLAFDMVRPGIAVYGQTPIP
CCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCHHHHHHCCCEEEECCCCCC
ALGDMGLRPAMTLRCPVAQTRSIKAGDGVSYGHTWIAQRDTTVALLPIGYADGVYRSLSG
CCCCCCCCCCEEEECCCHHCCCCCCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHCC
RLQVLINGRLRPGVGRICMDQFVVDLGPGPVDVSDGDEAILFGPGTRGEHTAQDWAEIIG
EEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHH
TINYEIVTSPRGRVVRTYRRESR
CCCEEEEECCCCHHHHHHHHCCC
>Mature Secondary Structure
MQTSETTVTPTAQVVVDLDAISHNVALLRDRAGSAQVMPVLKADGYGHGATEVAKVVLDA
CCCCCCCCCCCEEEEEEHHHHHCCCEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHC
GVTELGVATVGEALALRADGITAPVLAWLHGPGTDFAPAVQADIQLAVSSVRQLGEILDA
CCHHHHHHHHHHHHEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VHRTGMTATLTVKADTGLSRNGVSPAEYPALLQRLAKAQAEDAVRVRGIMSHLACGDEPD
HHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
NPTNDRQAQRLTDMRRQAADAGVTFEVAHLCNSPAAMTRPDLAFDMVRPGIAVYGQTPIP
CCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHCCCCCCCCCCHHHHHHCCCEEEECCCCCC
ALGDMGLRPAMTLRCPVAQTRSIKAGDGVSYGHTWIAQRDTTVALLPIGYADGVYRSLSG
CCCCCCCCCCEEEECCCHHCCCCCCCCCCCCCCEEEEECCCEEEEEECCCHHHHHHHHCC
RLQVLINGRLRPGVGRICMDQFVVDLGPGPVDVSDGDEAILFGPGTRGEHTAQDWAEIIG
EEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHH
TINYEIVTSPRGRVVRTYRRESR
CCCEEEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA