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The map label for this gene is yhcA [H]

Identifier: 108797545

GI number: 108797545

Start: 625315

End: 627078

Strand: Direct

Name: yhcA [H]

Synonym: Mmcs_0565

Alternate gene names: 108797545

Gene position: 625315-627078 (Clockwise)

Preceding gene: 108797539

Following gene: 108797546

Centisome position: 10.96

GC content: 67.97

Gene sequence:

>1764_bases
ATGTGTTCTGCGGCGTCCGCTCGTCGCTGCGCACCGTCGGATACGAAACGAACGAGACTGCAGATGACAACCGAGCTCAC
CGGCCGGCGCCGGATCGCCACCGATCGCGACCACCCCCTCTACAAGTGGGTGGTGCTCTCCAACACCACGCTGGGGATGC
TGCTCGCGACCGTCAACTCGTCGATCGTGCTGATCTCGCTGCCGGCGATCTTCCGCGGCATCGGCCTCAACCCCCTGCAG
CCCGCCAACGTGACCTACCTGCTGTGGCTGCTGATGGGATACATGGTGGTCACCGCGGTGCTCGTGGTGCTGTTCGGACG
GCTGGGCGACATGTTCGGCCGGGTCCGCATCTACAACCTGGGCTTCGTCATCTTCACGCTGTGTGCGCTCGCGCTGTCGT
TCCAACCGTTCGACCTCGACGCCGGCGCGTGGTGGCTGATCGGGTGGCGGGTGGTCCAGGGCGTCGGCGGTGCGATGCTG
ATCGCCTCCTCGGCGGCCATCCTCACCGATGCCTTCCCCGCGCATCAGCGCGGAATGGCGTTGGGCGTCAACATGGTTGC
CGCCGTCGCCGGTTCATTCCTCGGGCTGGTGATCGGCGGCGCGCTGTCCGAATGGCACTGGCAGGCGATCTTCTGGGTGG
GCGTCCCGATCGGCGTCCTCGGCACGGTCTGGGCGATGCGTTCGCTGCGCGAGGTCGGGGAGCGCAGCCCGGGCCGGCTC
GACTGGGCGGGTGCGGTGACGCTCGGCCTCGGGCTCACGGTGCTGCTCACCGGGATCACCTACAGCATCCAGCCCTACGG
CGGTTCCCCCACCGGGTGGGGCAACCCGTGGGTGCTCGGCGCGATCGCCTTCGGGGTGCTGGCGCTGGTGGCGTTCTGCG
TCATCGAACTGCGGGTCGATCAACCCCTGGTCGACATCCTGCTGTTCCGCATCACCGCGTTCGGCATGGGCAACCTCGCC
GGGCTGATGTCCTCGGTCGGCCGCGGTGGACTGCAGTTCATGCTGATCATCTGGCTGCAGGGCATCTGGCTGCCGCTGCG
GGGCTACGACTTCGAGGCCACCCCACTGTGGGCGGCGATCTACATGCTGCCGTTGACCTTCGGATTCCTCGTGGCCGGAC
CTCTGTCGGGGTGGCTGTCCGACCGCTACGGCGCCCGCCCGTTCACCGTCGGCGGCATGCTGCTGATGTGTGCCACCTTC
GTCGCGCTGGTGCTGATCCCCGTCGACTTCGACTACTGGCTCTTCGCGACGCTGATCTTCCTCAACGGTGTCGGTGGCGG
GGTGTTCACCTCCCCGAATTCGGCCGCCATCATGTCGAGCGTGCCGGCGAGCGCGCGCGGCGCCGCCTCCGGGGTGCGGG
CCACGTTCTTCAATGCCGGCGGATCGCTGTCGATCGGGATCTTCTTCTCGCTCATGATCGTCGGGCTGGCCAACACGCTG
CCCGGAGCCATGAGCGCAGGCCTGCAGGCGCAGGGCGTCTCGGCGGCGGTCGCCGACGAGGTCGCAGGCACGCCGCCCGT
CGGCAGCCTGTTCGCGGCGTTCCTCGGCTACAACCCGATCGGCGAACTCCTGGAGCCGTCGCACGCGCTGCAACAGCCCG
GCGTCAACGCCGAGGTGCTCACCGGTCAGACCTTCTTCCCGCACCTGATCATCGAGCCCTTCCACACCGGACTGGTGGTG
GTGTTCGTCGCCGCCGCGGTGATGATGCTGATCGGCGCGGTGGCGTCGCTGTTCAACGCTGGGCGTTACGCCGAGCAAAC
GTGA

Upstream 100 bases:

>100_bases
GTGCGCGCTCCCGCGTGGTCGGTGGTGCGTTGCTCAACCTAGCGCAGACGCCGGATGGGGCGAACGCGAATTGCCGACCG
ATTATTTGTATAGCTAATAT

Downstream 100 bases:

>100_bases
TCATCCGGTGGGCGGCCCCCACGATCTGCTGCGAAGATACGTAGGTGCCCCTGCAGCTCATCAGCCGCGACGCGGAGTTG
AGCGCTGTCGACGACCTGCT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MCSAASARRCAPSDTKRTRLQMTTELTGRRRIATDRDHPLYKWVVLSNTTLGMLLATVNSSIVLISLPAIFRGIGLNPLQ
PANVTYLLWLLMGYMVVTAVLVVLFGRLGDMFGRVRIYNLGFVIFTLCALALSFQPFDLDAGAWWLIGWRVVQGVGGAML
IASSAAILTDAFPAHQRGMALGVNMVAAVAGSFLGLVIGGALSEWHWQAIFWVGVPIGVLGTVWAMRSLREVGERSPGRL
DWAGAVTLGLGLTVLLTGITYSIQPYGGSPTGWGNPWVLGAIAFGVLALVAFCVIELRVDQPLVDILLFRITAFGMGNLA
GLMSSVGRGGLQFMLIIWLQGIWLPLRGYDFEATPLWAAIYMLPLTFGFLVAGPLSGWLSDRYGARPFTVGGMLLMCATF
VALVLIPVDFDYWLFATLIFLNGVGGGVFTSPNSAAIMSSVPASARGAASGVRATFFNAGGSLSIGIFFSLMIVGLANTL
PGAMSAGLQAQGVSAAVADEVAGTPPVGSLFAAFLGYNPIGELLEPSHALQQPGVNAEVLTGQTFFPHLIIEPFHTGLVV
VFVAAAVMMLIGAVASLFNAGRYAEQT

Sequences:

>Translated_587_residues
MCSAASARRCAPSDTKRTRLQMTTELTGRRRIATDRDHPLYKWVVLSNTTLGMLLATVNSSIVLISLPAIFRGIGLNPLQ
PANVTYLLWLLMGYMVVTAVLVVLFGRLGDMFGRVRIYNLGFVIFTLCALALSFQPFDLDAGAWWLIGWRVVQGVGGAML
IASSAAILTDAFPAHQRGMALGVNMVAAVAGSFLGLVIGGALSEWHWQAIFWVGVPIGVLGTVWAMRSLREVGERSPGRL
DWAGAVTLGLGLTVLLTGITYSIQPYGGSPTGWGNPWVLGAIAFGVLALVAFCVIELRVDQPLVDILLFRITAFGMGNLA
GLMSSVGRGGLQFMLIIWLQGIWLPLRGYDFEATPLWAAIYMLPLTFGFLVAGPLSGWLSDRYGARPFTVGGMLLMCATF
VALVLIPVDFDYWLFATLIFLNGVGGGVFTSPNSAAIMSSVPASARGAASGVRATFFNAGGSLSIGIFFSLMIVGLANTL
PGAMSAGLQAQGVSAAVADEVAGTPPVGSLFAAFLGYNPIGELLEPSHALQQPGVNAEVLTGQTFFPHLIIEPFHTGLVV
VFVAAAVMMLIGAVASLFNAGRYAEQT
>Mature_587_residues
MCSAASARRCAPSDTKRTRLQMTTELTGRRRIATDRDHPLYKWVVLSNTTLGMLLATVNSSIVLISLPAIFRGIGLNPLQ
PANVTYLLWLLMGYMVVTAVLVVLFGRLGDMFGRVRIYNLGFVIFTLCALALSFQPFDLDAGAWWLIGWRVVQGVGGAML
IASSAAILTDAFPAHQRGMALGVNMVAAVAGSFLGLVIGGALSEWHWQAIFWVGVPIGVLGTVWAMRSLREVGERSPGRL
DWAGAVTLGLGLTVLLTGITYSIQPYGGSPTGWGNPWVLGAIAFGVLALVAFCVIELRVDQPLVDILLFRITAFGMGNLA
GLMSSVGRGGLQFMLIIWLQGIWLPLRGYDFEATPLWAAIYMLPLTFGFLVAGPLSGWLSDRYGARPFTVGGMLLMCATF
VALVLIPVDFDYWLFATLIFLNGVGGGVFTSPNSAAIMSSVPASARGAASGVRATFFNAGGSLSIGIFFSLMIVGLANTL
PGAMSAGLQAQGVSAAVADEVAGTPPVGSLFAAFLGYNPIGELLEPSHALQQPGVNAEVLTGQTFFPHLIIEPFHTGLVV
VFVAAAVMMLIGAVASLFNAGRYAEQT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=412, Percent_Identity=27.9126213592233, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI1790195, Length=345, Percent_Identity=26.3768115942029, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789042, Length=425, Percent_Identity=24, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788710, Length=435, Percent_Identity=22.9885057471264, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788392, Length=449, Percent_Identity=24.0534521158129, Blast_Score=71, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324954, Length=414, Percent_Identity=26.3285024154589, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6325455, Length=351, Percent_Identity=22.5071225071225, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 62206; Mature: 62206

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCSAASARRCAPSDTKRTRLQMTTELTGRRRIATDRDHPLYKWVVLSNTTLGMLLATVNS
CCCCCCCCCCCCCCCHHHHHEEHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCC
SIVLISLPAIFRGIGLNPLQPANVTYLLWLLMGYMVVTAVLVVLFGRLGDMFGRVRIYNL
CEEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHH
GFVIFTLCALALSFQPFDLDAGAWWLIGWRVVQGVGGAMLIASSAAILTDAFPAHQRGMA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCHHHCCHH
LGVNMVAAVAGSFLGLVIGGALSEWHWQAIFWVGVPIGVLGTVWAMRSLREVGERSPGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
DWAGAVTLGLGLTVLLTGITYSIQPYGGSPTGWGNPWVLGAIAFGVLALVAFCVIELRVD
CHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
QPLVDILLFRITAFGMGNLAGLMSSVGRGGLQFMLIIWLQGIWLPLRGYDFEATPLWAAI
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
YMLPLTFGFLVAGPLSGWLSDRYGARPFTVGGMLLMCATFVALVLIPVDFDYWLFATLIF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LNGVGGGVFTSPNSAAIMSSVPASARGAASGVRATFFNAGGSLSIGIFFSLMIVGLANTL
HHCCCCCCEECCCCHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHC
PGAMSAGLQAQGVSAAVADEVAGTPPVGSLFAAFLGYNPIGELLEPSHALQQPGVNAEVL
CHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCEEEE
TGQTFFPHLIIEPFHTGLVVVFVAAAVMMLIGAVASLFNAGRYAEQT
ECCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MCSAASARRCAPSDTKRTRLQMTTELTGRRRIATDRDHPLYKWVVLSNTTLGMLLATVNS
CCCCCCCCCCCCCCCHHHHHEEHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHCC
SIVLISLPAIFRGIGLNPLQPANVTYLLWLLMGYMVVTAVLVVLFGRLGDMFGRVRIYNL
CEEEEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEHH
GFVIFTLCALALSFQPFDLDAGAWWLIGWRVVQGVGGAMLIASSAAILTDAFPAHQRGMA
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCHHHCCHH
LGVNMVAAVAGSFLGLVIGGALSEWHWQAIFWVGVPIGVLGTVWAMRSLREVGERSPGRL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCC
DWAGAVTLGLGLTVLLTGITYSIQPYGGSPTGWGNPWVLGAIAFGVLALVAFCVIELRVD
CHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
QPLVDILLFRITAFGMGNLAGLMSSVGRGGLQFMLIIWLQGIWLPLRGYDFEATPLWAAI
CHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHEECCCCCCCCCHHHHHH
YMLPLTFGFLVAGPLSGWLSDRYGARPFTVGGMLLMCATFVALVLIPVDFDYWLFATLIF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LNGVGGGVFTSPNSAAIMSSVPASARGAASGVRATFFNAGGSLSIGIFFSLMIVGLANTL
HHCCCCCCEECCCCHHHHHCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHC
PGAMSAGLQAQGVSAAVADEVAGTPPVGSLFAAFLGYNPIGELLEPSHALQQPGVNAEVL
CHHHHCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHCCHHHHHCCCCCEEEE
TGQTFFPHLIIEPFHTGLVVVFVAAAVMMLIGAVASLFNAGRYAEQT
ECCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8969498 [H]