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The map label for this gene is gntR [H]

Identifier: 108797094

GI number: 108797094

Start: 128079

End: 128774

Strand: Reverse

Name: gntR [H]

Synonym: Mmcs_0114

Alternate gene names: 108797094

Gene position: 128774-128079 (Counterclockwise)

Preceding gene: 108797111

Following gene: 108797091

Centisome position: 2.26

GC content: 69.83

Gene sequence:

>696_bases
GTGAACGCCGCCCCCGTCGCACGACGTCCGGCGAGGCGGCGCGCCACTCGCCGCGAACAGCTCTCCGACGAGGTGGCGGG
GCATCTGCGTGCGGCGATCATGACCGGAGCACTGCGGCCAGGGACGTTCATCCGGCTCGACGAGACGGCCGCGGAGCTGG
GCGTGAGCATCACCCCGGTCCGGGAGGCGCTTCGGACATTGCGCGGCGAGGGGATGGTGCGGCTCGAGCCGCACCGCGGG
CACGTCGTGGTGCCGATGACGCGCGGGGACATCGAGGACATCTTCTGGCTGCAGGCGACGATCGCGGAGAAATTGGCCGA
GGCCGCCACCGAACGGATCAGCGAGACGCAGATCGAGGAGCTCGAGCAGCTCAACTCCGCGCTCGCCGAGGCGGTCGAGC
ATCAGGATCCGGAGGAGGTGGCGTTCGCGGAGTTCGCCTTCCACCGGGCGTTCAACCACGCATCGGGGCGGATCAAGCTC
GCGTGGTTCCTGTTGCACGTGGCGCGGTACCTGCCGCCACTGCTGTATGCGACGGATCCGAGCTGGGGCACGGACGCGGT
GGCCAGTCACCGGGAGTTGATCGCGGCGCTACGGCGGCGGGACGCGGAGACGGTGGTGCGGTTGACGACGGGGCAGTTCA
CCGACGGGGCGCAGAGGTTGATCGTCCGGCTGGAGAAGATCGGGCTCTGGGACTAG

Upstream 100 bases:

>100_bases
GTTGATATTTGATCAAACATTGGATGGCCCCGGTCACACTATGGCCAAGGCGCTTCGTGGACAACCCCGTCCGATCACGC
CGAAGAACCGGAGAGCACCC

Downstream 100 bases:

>100_bases
GCAACCCGGCTTCGCGCGCGTCTATGCGCTGCCGGCGCCCAAATGTTCGGCCCGGGCCTTGAGGTTGTCGGCCAGATAGT
CCAGCGTCTCGCCGATCGCC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: P28 protein [H]

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPVREALRTLRGEGMVRLEPHRG
HVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEVAFAEFAFHRAFNHASGRIKL
AWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRLIVRLEKIGLWD

Sequences:

>Translated_231_residues
MNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPVREALRTLRGEGMVRLEPHRG
HVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEVAFAEFAFHRAFNHASGRIKL
AWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRLIVRLEKIGLWD
>Mature_231_residues
MNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPVREALRTLRGEGMVRLEPHRG
HVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEELEQLNSALAEAVEHQDPEEVAFAEFAFHRAFNHASGRIKL
AWFLLHVARYLPPLLYATDPSWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRLIVRLEKIGLWD

Specific function: Transcriptional repressor of the gluconate operon (gntRKPZ), which encodes the proteins for gluconate utilization. Represses mRNA synthesis by binding to the gnt operator; the binding is suppressed by gluconate or glucono-delta-lactone [H]

COG id: COG1802

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081914, Length=187, Percent_Identity=27.2727272727273, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25881; Mature: 25881

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCHHHH
REALRTLRGEGMVRLEPHRGHVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEE
HHHHHHHHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQLNSALAEAVEHQDPEEVAFAEFAFHRAFNHASGRIKLAWFLLHVARYLPPLLYATDP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCC
SWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRLIVRLEKIGLWD
CCCHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNAAPVARRPARRRATRREQLSDEVAGHLRAAIMTGALRPGTFIRLDETAAELGVSITPV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCHHHH
REALRTLRGEGMVRLEPHRGHVVVPMTRGDIEDIFWLQATIAEKLAEAATERISETQIEE
HHHHHHHHCCCEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEQLNSALAEAVEHQDPEEVAFAEFAFHRAFNHASGRIKLAWFLLHVARYLPPLLYATDP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECCC
SWGTDAVASHRELIAALRRRDAETVVRLTTGQFTDGAQRLIVRLEKIGLWD
CCCHHHHHHHHHHHHHHHHCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8535972 [H]