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The map label for this gene is nuoL [H]

Identifier: 108764092

GI number: 108764092

Start: 1262587

End: 1264782

Strand: Reverse

Name: nuoL [H]

Synonym: MXAN_1082

Alternate gene names: 108764092

Gene position: 1264782-1262587 (Counterclockwise)

Preceding gene: 108763005

Following gene: 108758088

Centisome position: 13.84

GC content: 67.3

Gene sequence:

>2196_bases
GTGGCGCCAGACATCCTGGCGCCCTCGCTCTGGCTCATCATCGCGCTGCCCCTGCTGGGCGCGTTCATCTGCGGTGTGTT
CGGCAAGATGATGGGCCGGGCCAACGTCCAGCTCGTCGCCTGCGCGGCGGTGGCCGGCTCCTTCGTCCTGAGCCTGTTGG
CCTTCTGGGCCACCAGCCACCACAACCCCGAGACGGGTCGGCTGGCGGCCATCTTCCCCAACCCGTTCGGCATCGAGCGG
GACTTCGTGCGCTACGCGCTCGCGTACGACTACGGCACCTGGTTCTCGGTGGGCGACTTCCGGGTGAACTTCGGACTGAT
GGTGGACCATCTGTCCGGCATCCTGCTGCTCATCATCACCGGCGTCGGCTTCCTCATCCACCTGTACTCCACCAGCTACA
TGGAGCACGACGCCGCGTACTGGCGGTTCTTCGCGTACCTGAACCTGTTCGTCGCGGCGATGCTGACGCTGGTGCTGGCC
GACAACCTGATCCTGCTCTTCGTGGGCTGGGAGGGCGTCGGCATGGCCAGCTACCTGCTCATCGGCTTCTGGTACGACGA
CCCGGCCAAGGCCTGGGCTGGGCGCAAGGCCTTCGTCACCAACCGCATCGGTGACTTCGCGTTCCTCGTCGGCACCTTCC
TGCTGGTGCTGCTGGTCTCCGCCTTCACCCAGCAGTCGAACGCGGCGGACTACAACAACGCCGGCACCACCGCGCAGCAC
TACACGGCCGCGCTGGAGAAGAAGGGCCCGGTGACGTTCAAGGGCCTGGAGAAGATGGCCGAGGGCCTGGTGGACGGCTC
CGCGGACAAGGTCGACCTGAGCACCCCCATCGAGGCGGGCCCGCTGGAGGGCTACACCTTCGGCGGCGTGATGACGGTGG
CCATGCTGCTGTTCCTCCTGGGCGCCGCGGGCAAGAGCGCGCAGTTGCCCCTCTACGTCTGGCTGCCGGACGCCATGGCC
GGCCCGACGCCGGTCTCCGCCCTCATCCACGCCGCGACGATGGTGACCGCCGGCGTCTACCTGTTCAGCCGCATGTCCGC
GCTGCTGGTGCTGAGCCCCACCGCCATGGCGACCATCGCCATCATCGGCGCGCTCACCTCGCTGCTGGCAGCGCTCATCG
CCTTCGCGCAGGACGACATCAAGAAGGTGCTCGCCTACTCCACGGTGTCCCAGCTGGGCATCATGTTCATGGGCGTGGGC
ATGGGCATCTTCTGGGCGGCGGTGTTCCACCTGATGACGCACGCCTTCTTCAAGGCCTGCCTCTTCCTCGGCGCCGGCAG
CGTGATGCACGGCAACGGCGACGAGACGGACATCAAGAAGCTGGGAGGCCTGCGCAAGGAGATGCCCTGGACCTGGGCCA
CCTTCCTGGTCGCCACCCTGGCCATCACCGGCATCATCCCGCTGTCCGGCTTCTTCTCGAAGGACGCCATCCTGCACGGC
GTGCACCACAACCACCTGCAGGGCCTGGAGTGGGTGTCCAGCCTCGTCTACTACCTGGGCCTGCTCATCGCGGCGTCCAC
CGCGTTCTACATGACGCGCGTGTACCTGCTCACCTTCGAGGGTCCCCGCTCGAAGGAGGCCCGGGTGGCCCACGCCCATG
AGAGCGCCTGGCAGATGACCCTGCCGCTGGTGGTGCTGGCGGTCCTGAGCGTGGTCGCCGCACGTTACGCGTTCGGCATC
GACTTCCTCAACATGACGGCGCAGCCGGTGCTCGACAACTTCCTGAGCCCGGTGTTCAGCGCGACCAAGCGCATCACCGA
CGCCAGCACGCTGGTGGCGCTGGACACCAGCCGCCCGCAGTTGGTGCCGGACTACCTCAAGGCCTGGGCCGTGGCCCTGG
CGGGTGGCGGCGCGGCGGCCTTCCTCTACCTGCGCTACTTCCCTTCGCGCGTGGGTCTGCCGGATCCCGCCTTCATCCGC
GCGGTGCGCCCCCTCGCGCTCAACAAGTTCTACGTGGACGAGCTCTATGAGCTGATTGTCATCCGTCCCGTGAAGTTCAT
GAGCTTCCTCCTCTTCCGCGTGGTGGACGCGCTCGTCATCGACACCGTGGCGGTCCGCGGCACGGCGTGGGTGACGGCGC
GCGTGGGCAGTGCGCTCCGCTACGTGCAGTCGGGCGATGCCCAGGCCTACGCCGCTGTGATGGCCATCGCCCTGTTGGGC
GGGATGGCCTACGCCCTCATCCAGGTGATGCAATGA

Upstream 100 bases:

>100_bases
CGGGGCAGCATCCTGCTGGAAGACCTCCGGACGATGAAGCACTGATGCCCCCCCAGGAGCCAATGTCATGACTCTCGTCG
AATTCTTCCGGGCGGCACCC

Downstream 100 bases:

>100_bases
GCTTCTTCGACAACCACCTGCTCAACCTCGTCGTCTTCCTGCCGCTGGTGTTCGCGGCGCTGGTGGCGCTGCTGCCTGCC
GGCGAGAGCGGCCAGATTCG

Product: NADH dehydrogenase I subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MAPDILAPSLWLIIALPLLGAFICGVFGKMMGRANVQLVACAAVAGSFVLSLLAFWATSHHNPETGRLAAIFPNPFGIER
DFVRYALAYDYGTWFSVGDFRVNFGLMVDHLSGILLLIITGVGFLIHLYSTSYMEHDAAYWRFFAYLNLFVAAMLTLVLA
DNLILLFVGWEGVGMASYLLIGFWYDDPAKAWAGRKAFVTNRIGDFAFLVGTFLLVLLVSAFTQQSNAADYNNAGTTAQH
YTAALEKKGPVTFKGLEKMAEGLVDGSADKVDLSTPIEAGPLEGYTFGGVMTVAMLLFLLGAAGKSAQLPLYVWLPDAMA
GPTPVSALIHAATMVTAGVYLFSRMSALLVLSPTAMATIAIIGALTSLLAALIAFAQDDIKKVLAYSTVSQLGIMFMGVG
MGIFWAAVFHLMTHAFFKACLFLGAGSVMHGNGDETDIKKLGGLRKEMPWTWATFLVATLAITGIIPLSGFFSKDAILHG
VHHNHLQGLEWVSSLVYYLGLLIAASTAFYMTRVYLLTFEGPRSKEARVAHAHESAWQMTLPLVVLAVLSVVAARYAFGI
DFLNMTAQPVLDNFLSPVFSATKRITDASTLVALDTSRPQLVPDYLKAWAVALAGGGAAAFLYLRYFPSRVGLPDPAFIR
AVRPLALNKFYVDELYELIVIRPVKFMSFLLFRVVDALVIDTVAVRGTAWVTARVGSALRYVQSGDAQAYAAVMAIALLG
GMAYALIQVMQ

Sequences:

>Translated_731_residues
MAPDILAPSLWLIIALPLLGAFICGVFGKMMGRANVQLVACAAVAGSFVLSLLAFWATSHHNPETGRLAAIFPNPFGIER
DFVRYALAYDYGTWFSVGDFRVNFGLMVDHLSGILLLIITGVGFLIHLYSTSYMEHDAAYWRFFAYLNLFVAAMLTLVLA
DNLILLFVGWEGVGMASYLLIGFWYDDPAKAWAGRKAFVTNRIGDFAFLVGTFLLVLLVSAFTQQSNAADYNNAGTTAQH
YTAALEKKGPVTFKGLEKMAEGLVDGSADKVDLSTPIEAGPLEGYTFGGVMTVAMLLFLLGAAGKSAQLPLYVWLPDAMA
GPTPVSALIHAATMVTAGVYLFSRMSALLVLSPTAMATIAIIGALTSLLAALIAFAQDDIKKVLAYSTVSQLGIMFMGVG
MGIFWAAVFHLMTHAFFKACLFLGAGSVMHGNGDETDIKKLGGLRKEMPWTWATFLVATLAITGIIPLSGFFSKDAILHG
VHHNHLQGLEWVSSLVYYLGLLIAASTAFYMTRVYLLTFEGPRSKEARVAHAHESAWQMTLPLVVLAVLSVVAARYAFGI
DFLNMTAQPVLDNFLSPVFSATKRITDASTLVALDTSRPQLVPDYLKAWAVALAGGGAAAFLYLRYFPSRVGLPDPAFIR
AVRPLALNKFYVDELYELIVIRPVKFMSFLLFRVVDALVIDTVAVRGTAWVTARVGSALRYVQSGDAQAYAAVMAIALLG
GMAYALIQVMQ
>Mature_730_residues
APDILAPSLWLIIALPLLGAFICGVFGKMMGRANVQLVACAAVAGSFVLSLLAFWATSHHNPETGRLAAIFPNPFGIERD
FVRYALAYDYGTWFSVGDFRVNFGLMVDHLSGILLLIITGVGFLIHLYSTSYMEHDAAYWRFFAYLNLFVAAMLTLVLAD
NLILLFVGWEGVGMASYLLIGFWYDDPAKAWAGRKAFVTNRIGDFAFLVGTFLLVLLVSAFTQQSNAADYNNAGTTAQHY
TAALEKKGPVTFKGLEKMAEGLVDGSADKVDLSTPIEAGPLEGYTFGGVMTVAMLLFLLGAAGKSAQLPLYVWLPDAMAG
PTPVSALIHAATMVTAGVYLFSRMSALLVLSPTAMATIAIIGALTSLLAALIAFAQDDIKKVLAYSTVSQLGIMFMGVGM
GIFWAAVFHLMTHAFFKACLFLGAGSVMHGNGDETDIKKLGGLRKEMPWTWATFLVATLAITGIIPLSGFFSKDAILHGV
HHNHLQGLEWVSSLVYYLGLLIAASTAFYMTRVYLLTFEGPRSKEARVAHAHESAWQMTLPLVVLAVLSVVAARYAFGID
FLNMTAQPVLDNFLSPVFSATKRITDASTLVALDTSRPQLVPDYLKAWAVALAGGGAAAFLYLRYFPSRVGLPDPAFIRA
VRPLALNKFYVDELYELIVIRPVKFMSFLLFRVVDALVIDTVAVRGTAWVTARVGSALRYVQSGDAQAYAAVMAIALLGG
MAYALIQVMQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=333, Percent_Identity=36.9369369369369, Blast_Score=184, Evalue=3e-46,
Organism=Escherichia coli, GI1788614, Length=628, Percent_Identity=38.8535031847134, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1788829, Length=395, Percent_Identity=32.1518987341772, Blast_Score=159, Evalue=6e-40,
Organism=Escherichia coli, GI1788827, Length=480, Percent_Identity=27.5, Blast_Score=122, Evalue=1e-28,
Organism=Escherichia coli, GI1788831, Length=417, Percent_Identity=27.5779376498801, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI2367154, Length=211, Percent_Identity=33.175355450237, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788613, Length=385, Percent_Identity=26.4935064935065, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 79092; Mature: 78961

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPDILAPSLWLIIALPLLGAFICGVFGKMMGRANVQLVACAAVAGSFVLSLLAFWATSH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
HNPETGRLAAIFPNPFGIERDFVRYALAYDYGTWFSVGDFRVNFGLMVDHLSGILLLIIT
CCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCEEEEHHHHHHHHHHHHHHHHH
GVGFLIHLYSTSYMEHDAAYWRFFAYLNLFVAAMLTLVLADNLILLFVGWEGVGMASYLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
IGFWYDDPAKAWAGRKAFVTNRIGDFAFLVGTFLLVLLVSAFTQQSNAADYNNAGTTAQH
EEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
YTAALEKKGPVTFKGLEKMAEGLVDGSADKVDLSTPIEAGPLEGYTFGGVMTVAMLLFLL
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
GAAGKSAQLPLYVWLPDAMAGPTPVSALIHAATMVTAGVYLFSRMSALLVLSPTAMATIA
CCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIGALTSLLAALIAFAQDDIKKVLAYSTVSQLGIMFMGVGMGIFWAAVFHLMTHAFFKAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLGAGSVMHGNGDETDIKKLGGLRKEMPWTWATFLVATLAITGIIPLSGFFSKDAILHG
HHHCCCCEECCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHC
VHHNHLQGLEWVSSLVYYLGLLIAASTAFYMTRVYLLTFEGPRSKEARVAHAHESAWQMT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHH
LPLVVLAVLSVVAARYAFGIDFLNMTAQPVLDNFLSPVFSATKRITDASTLVALDTSRPQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
LVPDYLKAWAVALAGGGAAAFLYLRYFPSRVGLPDPAFIRAVRPLALNKFYVDELYELIV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRPVKFMSFLLFRVVDALVIDTVAVRGTAWVTARVGSALRYVQSGDAQAYAAVMAIALLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GMAYALIQVMQ
HHHHHHHHHCC
>Mature Secondary Structure 
APDILAPSLWLIIALPLLGAFICGVFGKMMGRANVQLVACAAVAGSFVLSLLAFWATSH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
HNPETGRLAAIFPNPFGIERDFVRYALAYDYGTWFSVGDFRVNFGLMVDHLSGILLLIIT
CCCCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEEECCEEEEHHHHHHHHHHHHHHHHH
GVGFLIHLYSTSYMEHDAAYWRFFAYLNLFVAAMLTLVLADNLILLFVGWEGVGMASYLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHH
IGFWYDDPAKAWAGRKAFVTNRIGDFAFLVGTFLLVLLVSAFTQQSNAADYNNAGTTAQH
EEEEECCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
YTAALEKKGPVTFKGLEKMAEGLVDGSADKVDLSTPIEAGPLEGYTFGGVMTVAMLLFLL
HHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
GAAGKSAQLPLYVWLPDAMAGPTPVSALIHAATMVTAGVYLFSRMSALLVLSPTAMATIA
CCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IIGALTSLLAALIAFAQDDIKKVLAYSTVSQLGIMFMGVGMGIFWAAVFHLMTHAFFKAC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFLGAGSVMHGNGDETDIKKLGGLRKEMPWTWATFLVATLAITGIIPLSGFFSKDAILHG
HHHCCCCEECCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHC
VHHNHLQGLEWVSSLVYYLGLLIAASTAFYMTRVYLLTFEGPRSKEARVAHAHESAWQMT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHH
LPLVVLAVLSVVAARYAFGIDFLNMTAQPVLDNFLSPVFSATKRITDASTLVALDTSRPQ
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
LVPDYLKAWAVALAGGGAAAFLYLRYFPSRVGLPDPAFIRAVRPLALNKFYVDELYELIV
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IRPVKFMSFLLFRVVDALVIDTVAVRGTAWVTARVGSALRYVQSGDAQAYAAVMAIALLG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GMAYALIQVMQ
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]