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The map label for this gene is dtpA [H]

Identifier: 108764021

GI number: 108764021

Start: 3036941

End: 3038395

Strand: Reverse

Name: dtpA [H]

Synonym: MXAN_2608

Alternate gene names: 108764021

Gene position: 3038395-3036941 (Counterclockwise)

Preceding gene: 108758401

Following gene: 108759784

Centisome position: 33.24

GC content: 65.36

Gene sequence:

>1455_bases
ATGGCCCAGGCACCCGCCGCGCAGAGCAACAAGTTCCCGCCGCAAATCCCCTTCATCATCGGTAACGAGGCGTGTGAGCG
CTTCAGCTTCTACGGGATGCGGAACATCCTCACGGTGTTCCTCATCGACTACCTGCTGCGCACGCAGATACCGGACAACG
CGCTGCGGGAGGCCGAAGCGAAGAGCTTGATGCACACGTTCATGGCGGGCGTGTACTTCTTCCCGCTCATCGGCGGCTAC
CTGGCGGACCGGTTCTTCGGGAAGTACCGCATCATCCTGGGGCTGAGCCTGGTGTACTGCCTGGGCCACGCGTGCCTCGC
CATCTTCGAGAACAACGTCACGGGGTTCTTCACGGGCCTGGCGCTCATCGCCATTGGCAGTGGCGGAATCAAGCCCTGCG
TGGCGGCCATGGTGGGGGACCAGTTCAATGAGTCCAACAGCCACCTGGTGAAGAAGGTCTTCGCCATCTTCTACTGGACC
ATCAACTTCGGCTCGTTCTTCGCGTCGTTGTTCATCCCCCTGCTGCTCAAGCACTTCGGGCCGTCGGTGGCCTTCGGCAT
CCCCGGGGTGCTGATGTTCATCGCGACGTTCATCTTCTGGGCGGGCCGTCACAAGTACGTCCGGGTGCCGGCCACGGGCG
CCAACCCGCACAGCTTCTTCAAGGTGGTGGCCAGCGCACTGCGCAACCGCGGCCAGGGCGGCGGCTGGCTGGACGGCGCG
AAGCGGGAGCACCCCGAGGAGGCCGTGGACGGCGTGAAGGCGGTGTTCCGGGTGAGCGCGCTGCTGCTCCCCTTCGTGCC
CTTCTTCTGGATGCTCTTCGACCAGAAGGCGTCCACGTGGGTGGTGCAGGCCCGGTCCATGGACCCGCAGGTGGGGCCGT
TCACCTTCCAGGCCAGCCAGATGCAGTTCATCAACCCGCTGCTGGTGATGATTCTCATCCCCTTCCTGACGGCCGTCGTC
TACCCAGCCTTCCAGCGCTTCGGCTGGGAGCTGACGCCGCTGCGGCGCATGCCCCTGGGCCTGGTGGTGGGCGCGCTGTC
GTTCATCATCGCCGGCATCTTCCAGGTCACGATGGAAGGCGGCACGACGCTGAACATCGCGTGGCAGATTCTGCCGTACA
TCGTGCTGACGCTGGGCGAAATCCTGATGTCCACCACGGGCCTGGAGTTCGCGTACACGCAGGCCCCGCGTGAGATGAAG
GGCACCATCCAGAGCGTGTGGCTGGTGACGAACACGCTGGCCAACGCGGCGGTGGCCATCACCGCGAAGCTCAACGTCTT
CACGGGCTCCGGGCAGTTCTTCTTCTACGCCGGCTTCGCCCTGGTGGCCGCAGTGGGAATGGCCCTGGTGGCCCGCCGCT
ACGTGGTGCGTGACTACTACCAGACGTCCGCGCCCATCCCCACCGAGGAGCGCTCCGCTGCCGGCGTGACGCCCGGCTCG
GCGAAGTCCGCGTAG

Upstream 100 bases:

>100_bases
CCCCTTTCGTTCGGTGGAGTCCCGGCGGCCCGTTGGGTAGGGTGCGGCTTCTCGGAATCTAGGAGCCCCCACCTTTCGTC
ACGAGGGAGCACCCCGTCGC

Downstream 100 bases:

>100_bases
CCAGGCGGTCAGCCCGCGCAGTGAACGCCGGTGCACCTGTAAGGTGTGCCGGCGTTTGTGTTTCAGGCGTGGCGCCAGCA
GTCCGCGAACAGAAACGCCG

Product: proton/peptide symporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MAQAPAAQSNKFPPQIPFIIGNEACERFSFYGMRNILTVFLIDYLLRTQIPDNALREAEAKSLMHTFMAGVYFFPLIGGY
LADRFFGKYRIILGLSLVYCLGHACLAIFENNVTGFFTGLALIAIGSGGIKPCVAAMVGDQFNESNSHLVKKVFAIFYWT
INFGSFFASLFIPLLLKHFGPSVAFGIPGVLMFIATFIFWAGRHKYVRVPATGANPHSFFKVVASALRNRGQGGGWLDGA
KREHPEEAVDGVKAVFRVSALLLPFVPFFWMLFDQKASTWVVQARSMDPQVGPFTFQASQMQFINPLLVMILIPFLTAVV
YPAFQRFGWELTPLRRMPLGLVVGALSFIIAGIFQVTMEGGTTLNIAWQILPYIVLTLGEILMSTTGLEFAYTQAPREMK
GTIQSVWLVTNTLANAAVAITAKLNVFTGSGQFFFYAGFALVAAVGMALVARRYVVRDYYQTSAPIPTEERSAAGVTPGS
AKSA

Sequences:

>Translated_484_residues
MAQAPAAQSNKFPPQIPFIIGNEACERFSFYGMRNILTVFLIDYLLRTQIPDNALREAEAKSLMHTFMAGVYFFPLIGGY
LADRFFGKYRIILGLSLVYCLGHACLAIFENNVTGFFTGLALIAIGSGGIKPCVAAMVGDQFNESNSHLVKKVFAIFYWT
INFGSFFASLFIPLLLKHFGPSVAFGIPGVLMFIATFIFWAGRHKYVRVPATGANPHSFFKVVASALRNRGQGGGWLDGA
KREHPEEAVDGVKAVFRVSALLLPFVPFFWMLFDQKASTWVVQARSMDPQVGPFTFQASQMQFINPLLVMILIPFLTAVV
YPAFQRFGWELTPLRRMPLGLVVGALSFIIAGIFQVTMEGGTTLNIAWQILPYIVLTLGEILMSTTGLEFAYTQAPREMK
GTIQSVWLVTNTLANAAVAITAKLNVFTGSGQFFFYAGFALVAAVGMALVARRYVVRDYYQTSAPIPTEERSAAGVTPGS
AKSA
>Mature_483_residues
AQAPAAQSNKFPPQIPFIIGNEACERFSFYGMRNILTVFLIDYLLRTQIPDNALREAEAKSLMHTFMAGVYFFPLIGGYL
ADRFFGKYRIILGLSLVYCLGHACLAIFENNVTGFFTGLALIAIGSGGIKPCVAAMVGDQFNESNSHLVKKVFAIFYWTI
NFGSFFASLFIPLLLKHFGPSVAFGIPGVLMFIATFIFWAGRHKYVRVPATGANPHSFFKVVASALRNRGQGGGWLDGAK
REHPEEAVDGVKAVFRVSALLLPFVPFFWMLFDQKASTWVVQARSMDPQVGPFTFQASQMQFINPLLVMILIPFLTAVVY
PAFQRFGWELTPLRRMPLGLVVGALSFIIAGIFQVTMEGGTTLNIAWQILPYIVLTLGEILMSTTGLEFAYTQAPREMKG
TIQSVWLVTNTLANAAVAITAKLNVFTGSGQFFFYAGFALVAAVGMALVARRYVVRDYYQTSAPIPTEERSAAGVTPGSA
KSA

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=438, Percent_Identity=33.1050228310502, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI226371746, Length=355, Percent_Identity=37.4647887323944, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI226371748, Length=347, Percent_Identity=36.0230547550432, Blast_Score=216, Evalue=3e-56,
Organism=Homo sapiens, GI21717816, Length=457, Percent_Identity=23.4135667396061, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI7706117, Length=530, Percent_Identity=21.8867924528302, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI282847420, Length=501, Percent_Identity=20.7584830339321, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1787922, Length=437, Percent_Identity=23.5697940503432, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1790572, Length=194, Percent_Identity=32.4742268041237, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789911, Length=415, Percent_Identity=24.578313253012, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786927, Length=193, Percent_Identity=27.4611398963731, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71987453, Length=376, Percent_Identity=38.563829787234, Blast_Score=234, Evalue=7e-62,
Organism=Caenorhabditis elegans, GI17541704, Length=382, Percent_Identity=35.0785340314136, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17569141, Length=394, Percent_Identity=31.4720812182741, Blast_Score=190, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6322946, Length=530, Percent_Identity=26.0377358490566, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28571102, Length=368, Percent_Identity=35.8695652173913, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28571100, Length=368, Percent_Identity=35.8695652173913, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI28571098, Length=368, Percent_Identity=35.8695652173913, Blast_Score=221, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24639583, Length=337, Percent_Identity=40.3560830860534, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24639581, Length=337, Percent_Identity=40.3560830860534, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24639585, Length=337, Percent_Identity=40.3560830860534, Blast_Score=220, Evalue=2e-57,
Organism=Drosophila melanogaster, GI24645459, Length=477, Percent_Identity=28.3018867924528, Blast_Score=169, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53184; Mature: 53053

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAPAAQSNKFPPQIPFIIGNEACERFSFYGMRNILTVFLIDYLLRTQIPDNALREAEA
CCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
KSLMHTFMAGVYFFPLIGGYLADRFFGKYRIILGLSLVYCLGHACLAIFENNVTGFFTGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ALIAIGSGGIKPCVAAMVGDQFNESNSHLVKKVFAIFYWTINFGSFFASLFIPLLLKHFG
HHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSVAFGIPGVLMFIATFIFWAGRHKYVRVPATGANPHSFFKVVASALRNRGQGGGWLDGA
CCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
KREHPEEAVDGVKAVFRVSALLLPFVPFFWMLFDQKASTWVVQARSMDPQVGPFTFQASQ
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEECHHH
MQFINPLLVMILIPFLTAVVYPAFQRFGWELTPLRRMPLGLVVGALSFIIAGIFQVTMEG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTTLNIAWQILPYIVLTLGEILMSTTGLEFAYTQAPREMKGTIQSVWLVTNTLANAAVAI
CCEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHEEEE
TAKLNVFTGSGQFFFYAGFALVAAVGMALVARRYVVRDYYQTSAPIPTEERSAAGVTPGS
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
AKSA
CCCC
>Mature Secondary Structure 
AQAPAAQSNKFPPQIPFIIGNEACERFSFYGMRNILTVFLIDYLLRTQIPDNALREAEA
CCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH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CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA