Click here to switch to the map view.

The map label for this gene is nadA [H]

Identifier: 108759784

GI number: 108759784

Start: 3027844

End: 3028776

Strand: Reverse

Name: nadA [H]

Synonym: MXAN_2603

Alternate gene names: 108759784

Gene position: 3028776-3027844 (Counterclockwise)

Preceding gene: 108764021

Following gene: 108761129

Centisome position: 33.14

GC content: 63.34

Gene sequence:

>933_bases
ATGCGCGCCGAAGTCGACTACGCGAAGGAAATCCAGGAGTTCAAGCGTTCCATGAACGCAGTCATCCTGGCGCACTATTA
CCAGGAGAGCGAAGTTCAGGACCTCGCGGATTTCGTGGGAGACAGCCTGGCGCTGGCGCAAGCCGCGGCGAGCACGAAGG
CAGACGTCATCGTCTTCTGTGGCGTCCATTTCATGGCGGAGACGGCGAAGATTCTCAATCCGTCCCGGCAGGTGCTGTTG
CCGGACCTCAAGGCGGGCTGTTCGCTGTCGGACCGGTGCCCGCCGGGAGCCTTCAAGGCGTTCAAGGACAAACACCCGAA
CGCCTTCGTGGTGAGCTACGTCAACAGCTCCGCCGCGGTGAAGGCCATGAGCGACGTCATCTGCACGTCGTCCAACGCGG
TGAAAATCGTGAACCAGGTGCCGAAGGACCGGCAGATTCTCTTCGCGCCGGACCAGCACCTCGGCCGCTACGTGATGAAG
CAGACGGGCCGCGACATGGTGCTGTGGCCGGGCAGCTGCATCGTCCACGAAATCTTCAGCGAGAAGAAACTGGTGCAGCT
GAAGGTGGAGTACCCGGAGGCGGAAGTGGTGGCCCACCCCGAGTGTGAGCAGGCGGTGCTGCGCCACGCGGACTTCATCG
GCTCCACCAAGGCGATTCTGGATTACGCGGTGCGTAGCCCGAAGCAGCAGTTCATCGTGGTGACGGAGGCGGGCATCATC
CACCAGATGAAGCGGGCCGCGCCGAACAAGACGTTCATTCCCGCGCCGCCGGACAACGGCTGCGCGTGCAATGAGTGCCC
GTACATGCGGCTGAACACGCTGGAGAAGCTCTGGCGGTGCATGAAGGAGCGCACGCCCGAGCTGACCATGCCCGAGGACC
TGCGCGAGCGTGCTCGCGCGCCGCTGCAACGCATGCTGGACTGGTCTCAGTAG

Upstream 100 bases:

>100_bases
CCCGCTTGATTCGCGGCCACCCATGCACCAGCGAAGTGGGGCAAACCGCACCCTGGCCGGCACTTCAAGTCCCGGTTAAA
GGTGGGAGTCGGGAGGTGCC

Downstream 100 bases:

>100_bases
TCCGCGGATGAACGGCAGCAGCGGACATTTGCCAACTCGCGTCTTGCACCCCGCGAAACACAATGCGATGGAGCCACCGT
GGCCTTCCGATTCCTCGCAG

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRAEVDYAKEIQEFKRSMNAVILAHYYQESEVQDLADFVGDSLALAQAAASTKADVIVFCGVHFMAETAKILNPSRQVLL
PDLKAGCSLSDRCPPGAFKAFKDKHPNAFVVSYVNSSAAVKAMSDVICTSSNAVKIVNQVPKDRQILFAPDQHLGRYVMK
QTGRDMVLWPGSCIVHEIFSEKKLVQLKVEYPEAEVVAHPECEQAVLRHADFIGSTKAILDYAVRSPKQQFIVVTEAGII
HQMKRAAPNKTFIPAPPDNGCACNECPYMRLNTLEKLWRCMKERTPELTMPEDLRERARAPLQRMLDWSQ

Sequences:

>Translated_310_residues
MRAEVDYAKEIQEFKRSMNAVILAHYYQESEVQDLADFVGDSLALAQAAASTKADVIVFCGVHFMAETAKILNPSRQVLL
PDLKAGCSLSDRCPPGAFKAFKDKHPNAFVVSYVNSSAAVKAMSDVICTSSNAVKIVNQVPKDRQILFAPDQHLGRYVMK
QTGRDMVLWPGSCIVHEIFSEKKLVQLKVEYPEAEVVAHPECEQAVLRHADFIGSTKAILDYAVRSPKQQFIVVTEAGII
HQMKRAAPNKTFIPAPPDNGCACNECPYMRLNTLEKLWRCMKERTPELTMPEDLRERARAPLQRMLDWSQ
>Mature_310_residues
MRAEVDYAKEIQEFKRSMNAVILAHYYQESEVQDLADFVGDSLALAQAAASTKADVIVFCGVHFMAETAKILNPSRQVLL
PDLKAGCSLSDRCPPGAFKAFKDKHPNAFVVSYVNSSAAVKAMSDVICTSSNAVKIVNQVPKDRQILFAPDQHLGRYVMK
QTGRDMVLWPGSCIVHEIFSEKKLVQLKVEYPEAEVVAHPECEQAVLRHADFIGSTKAILDYAVRSPKQQFIVVTEAGII
HQMKRAAPNKTFIPAPPDNGCACNECPYMRLNTLEKLWRCMKERTPELTMPEDLRERARAPLQRMLDWSQ

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=314, Percent_Identity=42.6751592356688, Blast_Score=258, Evalue=3e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34756; Mature: 34756

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAEVDYAKEIQEFKRSMNAVILAHYYQESEVQDLADFVGDSLALAQAAASTKADVIVFC
CCCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEE
GVHFMAETAKILNPSRQVLLPDLKAGCSLSDRCPPGAFKAFKDKHPNAFVVSYVNSSAAV
CHHHHHHHHHHHCCCHHEECCCHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCHHHH
KAMSDVICTSSNAVKIVNQVPKDRQILFAPDQHLGRYVMKQTGRDMVLWPGSCIVHEIFS
HHHHHHHHCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCEEEEECCHHHHHHHHC
EKKLVQLKVEYPEAEVVAHPECEQAVLRHADFIGSTKAILDYAVRSPKQQFIVVTEAGII
CCCEEEEEEECCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHH
HQMKRAAPNKTFIPAPPDNGCACNECPYMRLNTLEKLWRCMKERTPELTMPEDLRERARA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
PLQRMLDWSQ
HHHHHHCCCC
>Mature Secondary Structure
MRAEVDYAKEIQEFKRSMNAVILAHYYQESEVQDLADFVGDSLALAQAAASTKADVIVFC
CCCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEE
GVHFMAETAKILNPSRQVLLPDLKAGCSLSDRCPPGAFKAFKDKHPNAFVVSYVNSSAAV
CHHHHHHHHHHHCCCHHEECCCHHCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCHHHH
KAMSDVICTSSNAVKIVNQVPKDRQILFAPDQHLGRYVMKQTGRDMVLWPGSCIVHEIFS
HHHHHHHHCCCCCHHHHHHCCCCCEEEECCHHHHHHHHHHHCCCEEEEECCHHHHHHHHC
EKKLVQLKVEYPEAEVVAHPECEQAVLRHADFIGSTKAILDYAVRSPKQQFIVVTEAGII
CCCEEEEEEECCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCHHH
HQMKRAAPNKTFIPAPPDNGCACNECPYMRLNTLEKLWRCMKERTPELTMPEDLRERARA
HHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
PLQRMLDWSQ
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA