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The map label for this gene is atoS [H]

Identifier: 108763968

GI number: 108763968

Start: 5206001

End: 5207191

Strand: Reverse

Name: atoS [H]

Synonym: MXAN_4246

Alternate gene names: 108763968

Gene position: 5207191-5206001 (Counterclockwise)

Preceding gene: 108757701

Following gene: 108763091

Centisome position: 56.97

GC content: 68.01

Gene sequence:

>1191_bases
ATGGCGGAAACCTTGTTCGAGGAATTGAAGCGGTACGTGGGGTTCAGCTCGGCGGACGAGCAGGCTCTCGTGACCTTGCA
TGCCACCGCGAAGCCCCACTTCGCGCGCTTCGCTCGCGTCTTCTACGACCGCATCCTGGAGCACGAAGGGGCTCGGCAGG
CGCTTGAAGGGGGCGAGAGCCAGGTGGGCCACCTGCGCGGCACCCTGCAGGTGTGGATGGACCAGCTCCTCCGCGGCCCC
TGGGACGAGGCCTACTACGCGCTGCGCTGCCGCATTGGCCGCATGCACGTGCGCATCGCCCTGCCGCAGCACTACATGTT
CGGCGCGATGAACATCCTGCGGCAGGAGTTCAACAGCCACATCGACGCCACCTACCTGGAAGAGCCCGCGGCGCTCCGCG
CGGCCCGCTCCGCGGTGGGGAAGATTCTCGACCTGGAGCTGGCCATCATGCTCCACACGTACCGGGAAGATCTGCTGGCG
CAGCAGGCGCGCAGTGAGCGGCTGTCCACCTTTGGCCAACTGGTGGGTTCCATCGGCCACGAGCTGCGCAATCCGCTGGG
CGTCATCGAGACGTCGCTCTACATCCTCCGGGGGCGCCCGGGGGCCATGGACGAGCGCACGACGAAGCACCTGGACCGCA
TTGGCGACCAGGTGGGCATCGCCAACCGCATCGTCTCCGACCTGCTGGACATGATTCGGGACCGGCCCCTGCACCGGCAG
GAGGTCTGGTTGGACGAGGTCTGGCAGGAAGCGCTCAAGGCCGTGCAGCGGCCCGACGCTGTCGTCGTGAGCGCGGAGGG
ACTGACCTCATTGCCCGCGGTTCAAGGAGACGCGGGGCAGCTGCGCCAGGTGTTCGTGAACCTGCTCGACAACGCCGTCC
AGGCCCTGGAGGAGACGGGCGGGACGGTGTCACTGTCCGCTGCCACGCGCGAGCCGGAGATGGTGGAGCTGGTGCTGGAG
GATTCCGGGCCGGGCGTCAGCGACGTCATCCGCCGCCGCCTCTTCGAGCCGCTGATGACGACGAAGGCGCGCGGCATCGG
GCTCGGGCTCGCGCTGGTCAAGCGCATCGTGGAGCGGCATGGGGGGAGCATCGCGTATGTCCCCCGTCCCGGCGCGGGAG
CGCGCTTCGTGATTCGGCTTTCCCTCGTCGCTTCGGAGGAGACGCATGCGCCAGTACCTCCTGTTGGATGA

Upstream 100 bases:

>100_bases
GGGCCGTGGCCCCTGGGCGGCGTGCCGAGCCATCGCGAAGCGGGGGAGGAAGTTCCTGCGCTCATGCGTTCAGCGCGGAT
AGGCTCTTACCCCAGGACTC

Downstream 100 bases:

>100_bases
CAACGTGGCGTTCGCGGAGAACCTCGCGGAGATTCTGCGCGACGGCGGGGACGCGGCCACTGTCGTCACGAGCGGTGACG
AGGCCGTGCGGTTGGCGCGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MAETLFEELKRYVGFSSADEQALVTLHATAKPHFARFARVFYDRILEHEGARQALEGGESQVGHLRGTLQVWMDQLLRGP
WDEAYYALRCRIGRMHVRIALPQHYMFGAMNILRQEFNSHIDATYLEEPAALRAARSAVGKILDLELAIMLHTYREDLLA
QQARSERLSTFGQLVGSIGHELRNPLGVIETSLYILRGRPGAMDERTTKHLDRIGDQVGIANRIVSDLLDMIRDRPLHRQ
EVWLDEVWQEALKAVQRPDAVVVSAEGLTSLPAVQGDAGQLRQVFVNLLDNAVQALEETGGTVSLSAATREPEMVELVLE
DSGPGVSDVIRRRLFEPLMTTKARGIGLGLALVKRIVERHGGSIAYVPRPGAGARFVIRLSLVASEETHAPVPPVG

Sequences:

>Translated_396_residues
MAETLFEELKRYVGFSSADEQALVTLHATAKPHFARFARVFYDRILEHEGARQALEGGESQVGHLRGTLQVWMDQLLRGP
WDEAYYALRCRIGRMHVRIALPQHYMFGAMNILRQEFNSHIDATYLEEPAALRAARSAVGKILDLELAIMLHTYREDLLA
QQARSERLSTFGQLVGSIGHELRNPLGVIETSLYILRGRPGAMDERTTKHLDRIGDQVGIANRIVSDLLDMIRDRPLHRQ
EVWLDEVWQEALKAVQRPDAVVVSAEGLTSLPAVQGDAGQLRQVFVNLLDNAVQALEETGGTVSLSAATREPEMVELVLE
DSGPGVSDVIRRRLFEPLMTTKARGIGLGLALVKRIVERHGGSIAYVPRPGAGARFVIRLSLVASEETHAPVPPVG
>Mature_395_residues
AETLFEELKRYVGFSSADEQALVTLHATAKPHFARFARVFYDRILEHEGARQALEGGESQVGHLRGTLQVWMDQLLRGPW
DEAYYALRCRIGRMHVRIALPQHYMFGAMNILRQEFNSHIDATYLEEPAALRAARSAVGKILDLELAIMLHTYREDLLAQ
QARSERLSTFGQLVGSIGHELRNPLGVIETSLYILRGRPGAMDERTTKHLDRIGDQVGIANRIVSDLLDMIRDRPLHRQE
VWLDEVWQEALKAVQRPDAVVVSAEGLTSLPAVQGDAGQLRQVFVNLLDNAVQALEETGGTVSLSAATREPEMVELVLED
SGPGVSDVIRRRLFEPLMTTKARGIGLGLALVKRIVERHGGSIAYVPRPGAGARFVIRLSLVASEETHAPVPPVG

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=233, Percent_Identity=32.618025751073, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=32.7586206896552, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=31.390134529148, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790300, Length=254, Percent_Identity=27.5590551181102, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=29.004329004329, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=236, Percent_Identity=28.8135593220339, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=255, Percent_Identity=27.843137254902, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=25.6198347107438, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=291, Percent_Identity=27.1477663230241, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1786600, Length=288, Percent_Identity=28.4722222222222, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43978; Mature: 43847

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS50109 HIS_KIN ; PS00144 ASN_GLN_ASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETLFEELKRYVGFSSADEQALVTLHATAKPHFARFARVFYDRILEHEGARQALEGGES
CCHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCH
QVGHLRGTLQVWMDQLLRGPWDEAYYALRCRIGRMHVRIALPQHYMFGAMNILRQEFNSH
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCC
IDATYLEEPAALRAARSAVGKILDLELAIMLHTYREDLLAQQARSERLSTFGQLVGSIGH
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRNPLGVIETSLYILRGRPGAMDERTTKHLDRIGDQVGIANRIVSDLLDMIRDRPLHRQ
HHHCCHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVWLDEVWQEALKAVQRPDAVVVSAEGLTSLPAVQGDAGQLRQVFVNLLDNAVQALEETG
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GTVSLSAATREPEMVELVLEDSGPGVSDVIRRRLFEPLMTTKARGIGLGLALVKRIVERH
CEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GGSIAYVPRPGAGARFVIRLSLVASEETHAPVPPVG
CCCEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
AETLFEELKRYVGFSSADEQALVTLHATAKPHFARFARVFYDRILEHEGARQALEGGES
CHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCH
QVGHLRGTLQVWMDQLLRGPWDEAYYALRCRIGRMHVRIALPQHYMFGAMNILRQEFNSH
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHCC
IDATYLEEPAALRAARSAVGKILDLELAIMLHTYREDLLAQQARSERLSTFGQLVGSIGH
CCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRNPLGVIETSLYILRGRPGAMDERTTKHLDRIGDQVGIANRIVSDLLDMIRDRPLHRQ
HHHCCHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
EVWLDEVWQEALKAVQRPDAVVVSAEGLTSLPAVQGDAGQLRQVFVNLLDNAVQALEETG
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
GTVSLSAATREPEMVELVLEDSGPGVSDVIRRRLFEPLMTTKARGIGLGLALVKRIVERH
CEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
GGSIAYVPRPGAGARFVIRLSLVASEETHAPVPPVG
CCCEEEECCCCCCCEEEEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]