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The map label for this gene is alsR [H]

Identifier: 108757701

GI number: 108757701

Start: 5207592

End: 5208482

Strand: Reverse

Name: alsR [H]

Synonym: MXAN_4247

Alternate gene names: 108757701

Gene position: 5208482-5207592 (Counterclockwise)

Preceding gene: 108761932

Following gene: 108763968

Centisome position: 56.99

GC content: 66.11

Gene sequence:

>891_bases
ATGCGACTCGACCTCGCGGATCTTCGCTTGTTCCTCTGCATCGTGGATGCGGGGAGCATCACGCAAGGTGCCCAACGCGC
GAACCTGACGCTGGCATCCGCGAGCGAGCGCCTGCGAAGCATCGAGGATGCGGTGGGCGTCAAGCTGCTCGAGAGGCGGC
CTCGGGGCGTGGTGACGACCGAGGCCGGTGACGCACTCGTGCACCACGCTCGGTTGATCCTGCATCAACAGGAGCTGTTG
AAGGATGAGTTGAATGCGTTTGTTTCAGGCCGGCGCGGCACCATTCGCCTCTATGCCAACACCGCGGCGCTGACCGAGTA
CCTGCCCGAGAAGCTGGCGCCATGGCTTGCCAGGCACCCGAGGCTGAACATCGACCTGAGAGAGCGAACCAGCGCGGATA
TCGTCAAGGCGGTCGAGGCAGGCCTGGCGGAGGCCGGACTGATTTCGGACGCCGTGGAGACGGGCACGCTTCAAGTCCGC
CCGTTGGAGCCCGCCCCCCTGGTGCTCATCATCCCCGCCGGGCACCCGCTGGCTGCATCCAAGAGCCTCGCGCTCCGCGA
TGTGTATCGGGAGCCCTTCGTCGGCCTCGCGGCCGAGAGCGCCTTGCAGGAGCACATTGATGGGCACGCACGTCGCGCGG
GATTCGACGTGTCCTTCCGCGTCCGGATGAAGGGCTTCCGGGGGCTGTGCGAGATGGTGTCTCACGGCGTGGGCCTGGGC
ATCGTCCCGGAGCGCGTCGCCAATCGGCATCAGCGGGAGGGCACCTATCGGAAGGTGCCCCTTTCGGAGGCCTGGGCCCA
GCGTCGGCTCTGTGTCTGTTTCCAGGACTGGGACGGCCTGTCATCTCCTGTTCGTGCGTTGCTGGAGTACCTGCTCGGTG
GAGGGGAATGA

Upstream 100 bases:

>100_bases
CGACGTGCGCTGACTGGACCATCCGGCGTGCTCTGGCACAATGCGGAGCGTCTCGTGACTCCCTTCGGACGCACCGGAGG
CAGCGTGCGCAGGGGGCGCG

Downstream 100 bases:

>100_bases
CGGCACACCCGTGTCAAGGGGGAGCAGGCGCATACCAGAACAGAGTGCAGTCTGAGGGCTGTGGGGATTCGCCGTGCCCC
CATGTTCGCGTGCAAACCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MRLDLADLRLFLCIVDAGSITQGAQRANLTLASASERLRSIEDAVGVKLLERRPRGVVTTEAGDALVHHARLILHQQELL
KDELNAFVSGRRGTIRLYANTAALTEYLPEKLAPWLARHPRLNIDLRERTSADIVKAVEAGLAEAGLISDAVETGTLQVR
PLEPAPLVLIIPAGHPLAASKSLALRDVYREPFVGLAAESALQEHIDGHARRAGFDVSFRVRMKGFRGLCEMVSHGVGLG
IVPERVANRHQREGTYRKVPLSEAWAQRRLCVCFQDWDGLSSPVRALLEYLLGGGE

Sequences:

>Translated_296_residues
MRLDLADLRLFLCIVDAGSITQGAQRANLTLASASERLRSIEDAVGVKLLERRPRGVVTTEAGDALVHHARLILHQQELL
KDELNAFVSGRRGTIRLYANTAALTEYLPEKLAPWLARHPRLNIDLRERTSADIVKAVEAGLAEAGLISDAVETGTLQVR
PLEPAPLVLIIPAGHPLAASKSLALRDVYREPFVGLAAESALQEHIDGHARRAGFDVSFRVRMKGFRGLCEMVSHGVGLG
IVPERVANRHQREGTYRKVPLSEAWAQRRLCVCFQDWDGLSSPVRALLEYLLGGGE
>Mature_296_residues
MRLDLADLRLFLCIVDAGSITQGAQRANLTLASASERLRSIEDAVGVKLLERRPRGVVTTEAGDALVHHARLILHQQELL
KDELNAFVSGRRGTIRLYANTAALTEYLPEKLAPWLARHPRLNIDLRERTSADIVKAVEAGLAEAGLISDAVETGTLQVR
PLEPAPLVLIIPAGHPLAASKSLALRDVYREPFVGLAAESALQEHIDGHARRAGFDVSFRVRMKGFRGLCEMVSHGVGLG
IVPERVANRHQREGTYRKVPLSEAWAQRRLCVCFQDWDGLSSPVRALLEYLLGGGE

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=243, Percent_Identity=23.8683127572016, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787879, Length=297, Percent_Identity=22.8956228956229, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693105, Length=286, Percent_Identity=22.3776223776224, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787806, Length=298, Percent_Identity=23.1543624161074, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=22.7586206896552, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788887, Length=182, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788481, Length=290, Percent_Identity=23.7931034482759, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1788748, Length=243, Percent_Identity=22.2222222222222, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1789204, Length=240, Percent_Identity=22.5, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=26.6129032258064, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI2367136, Length=249, Percent_Identity=24.4979919678715, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789639, Length=122, Percent_Identity=29.5081967213115, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32491; Mature: 32491

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDLADLRLFLCIVDAGSITQGAQRANLTLASASERLRSIEDAVGVKLLERRPRGVVTT
CCCCHHHHHHHHHEECCCCCCCCCHHHCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EAGDALVHHARLILHQQELLKDELNAFVSGRRGTIRLYANTAALTEYLPEKLAPWLARHP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCC
RLNIDLRERTSADIVKAVEAGLAEAGLISDAVETGTLQVRPLEPAPLVLIIPAGHPLAAS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCC
KSLALRDVYREPFVGLAAESALQEHIDGHARRAGFDVSFRVRMKGFRGLCEMVSHGVGLG
CHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCC
IVPERVANRHQREGTYRKVPLSEAWAQRRLCVCFQDWDGLSSPVRALLEYLLGGGE
CCCHHHHHHHHHCCCEEECCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLDLADLRLFLCIVDAGSITQGAQRANLTLASASERLRSIEDAVGVKLLERRPRGVVTT
CCCCHHHHHHHHHEECCCCCCCCCHHHCEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
EAGDALVHHARLILHQQELLKDELNAFVSGRRGTIRLYANTAALTEYLPEKLAPWLARHP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHCC
RLNIDLRERTSADIVKAVEAGLAEAGLISDAVETGTLQVRPLEPAPLVLIIPAGHPLAAS
CCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEECCCCCCCC
KSLALRDVYREPFVGLAAESALQEHIDGHARRAGFDVSFRVRMKGFRGLCEMVSHGVGLG
CHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHCCCCEEEEEEHHHHHHHHHHHHCCCCCC
IVPERVANRHQREGTYRKVPLSEAWAQRRLCVCFQDWDGLSSPVRALLEYLLGGGE
CCCHHHHHHHHHCCCEEECCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]