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The map label for this gene is yyaJ [H]

Identifier: 108763885

GI number: 108763885

Start: 4661468

End: 4662733

Strand: Direct

Name: yyaJ [H]

Synonym: MXAN_3880

Alternate gene names: 108763885

Gene position: 4661468-4662733 (Clockwise)

Preceding gene: 108758219

Following gene: 108757385

Centisome position: 51.0

GC content: 67.22

Gene sequence:

>1266_bases
ATGAAATTCCTGAGAGAGCTCCGCTCGGTCCTCAACCTGACCGTGCTGGTGGCCGGGCTCGGCTACTTCGTCGACCTCTT
CGACATCACGCTGTTCGGCGTGGTGCGTGTCGCATCGCTCAAGGACATCGGCGTCACCGACCCGGCCGACATCCTCCAGA
GCGGCCTGCTCATCTACAACGCGCAGATGGTGGGCATGATGGTGGGCGGCCTGCTGTGGGGCGTGCTCGCCGACAAGCGC
GGACGCCTGTCGGTGATGTTCGGCTCCATCCTGCTCTACTCCTTCGCGAACCTGGCCAACGCCTTCGCCTGGGACGTCAC
CAGCTACGCCGTTCTCCGCTTCCTCGGAGGCGTGGGGCTCGCGGGTGAGCTGGGCGCGGCCATTACCCTGGTGGCGGAGT
CCCTGCCCAAGGAGAAGCGCGGCCTGGGGACCACCATCGTCGCCACGCTGGGCATGCTCGGCATCGTCGCCGCGGCCTTC
CTGGGCCAGCACATGCACTGGAAGACGGCCTACCTCACCGGCGGCTTCATGGGCCTCGCGCTGCTCTTCGCGCGCTTCAA
GGTGTCGGAGTCGGAGCTGTTCAGCAAGAAGATGGACCCCGCGCGCGCCAACCCGCTGCTGCTCCTCACCGGCGGCCGGT
TCATCAAGTACATCTGCTGCATCCTCATCGGCGTGCCCATCTACTTCACCACGGGCATCCTCTTCACCTTCGCGCCCGAG
CTGACGGCCGGCCTCAACGTCCAGGGCACCGTGACGGCCGGCAACGCCATCCTCTATGGCTCCATCGGCCTGACGCTGGG
TGACTTGCTGGCGGGCGTCTTCAGCCAGTGGCTCAAGAGCCGCAAGCGCGCGGTGGCGATGAACCTCACCGCGGGCTTCG
TGCTGATGCTCGTCTACGGCCTCACCCCGGGCCTCACCAGCACCATGGTGTACGGGCTGAGCTTCCTGATTGGCATCACC
GTGGGCTACTGGGCCGTGCTGGTGACCATGGCCGCCGAGCAGTTCGGCACCAACATCCGCGGCACCGTGGCCACCACCGT
CCCCAACTTCGTGCGTGGCTCGGCGGCGCTCGCGGCCAGCGGCTTCGCCTACCTGAAGGGCGAGATGTCGGTGTCCACCG
CGGCGCTCATCGTCGGTAGCATCTGCTTCGGCCTGGCGCTGCTGGCCCTCACCCGGCTGGAAGAGACGTTCCACCGGGAC
CTGGATTACGAAGAGACGGCGAACGGCCCGCAGCCGGCCGCCCAGCCCTCCCAGTCCGGCACCTGA

Upstream 100 bases:

>100_bases
GGCCATGGCCTGAAGGTGAATTCAGGTTCATGCAGTGCGTCATGCATGCCCCTGCGCGGGGCGCTTGCTCCTCGCGCGCC
AAAGTCCGTTAATCGGGCGT

Downstream 100 bases:

>100_bases
CGCACGGCGCGGCGCTCACGGGGCGCCGCGCTTTGAATCGGACGTTCGCCCCGGCAGCCGTTGCTCCGGGGCCGACGGGA
TGCATACAGCGCGCACATGG

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MKFLRELRSVLNLTVLVAGLGYFVDLFDITLFGVVRVASLKDIGVTDPADILQSGLLIYNAQMVGMMVGGLLWGVLADKR
GRLSVMFGSILLYSFANLANAFAWDVTSYAVLRFLGGVGLAGELGAAITLVAESLPKEKRGLGTTIVATLGMLGIVAAAF
LGQHMHWKTAYLTGGFMGLALLFARFKVSESELFSKKMDPARANPLLLLTGGRFIKYICCILIGVPIYFTTGILFTFAPE
LTAGLNVQGTVTAGNAILYGSIGLTLGDLLAGVFSQWLKSRKRAVAMNLTAGFVLMLVYGLTPGLTSTMVYGLSFLIGIT
VGYWAVLVTMAAEQFGTNIRGTVATTVPNFVRGSAALAASGFAYLKGEMSVSTAALIVGSICFGLALLALTRLEETFHRD
LDYEETANGPQPAAQPSQSGT

Sequences:

>Translated_421_residues
MKFLRELRSVLNLTVLVAGLGYFVDLFDITLFGVVRVASLKDIGVTDPADILQSGLLIYNAQMVGMMVGGLLWGVLADKR
GRLSVMFGSILLYSFANLANAFAWDVTSYAVLRFLGGVGLAGELGAAITLVAESLPKEKRGLGTTIVATLGMLGIVAAAF
LGQHMHWKTAYLTGGFMGLALLFARFKVSESELFSKKMDPARANPLLLLTGGRFIKYICCILIGVPIYFTTGILFTFAPE
LTAGLNVQGTVTAGNAILYGSIGLTLGDLLAGVFSQWLKSRKRAVAMNLTAGFVLMLVYGLTPGLTSTMVYGLSFLIGIT
VGYWAVLVTMAAEQFGTNIRGTVATTVPNFVRGSAALAASGFAYLKGEMSVSTAALIVGSICFGLALLALTRLEETFHRD
LDYEETANGPQPAAQPSQSGT
>Mature_421_residues
MKFLRELRSVLNLTVLVAGLGYFVDLFDITLFGVVRVASLKDIGVTDPADILQSGLLIYNAQMVGMMVGGLLWGVLADKR
GRLSVMFGSILLYSFANLANAFAWDVTSYAVLRFLGGVGLAGELGAAITLVAESLPKEKRGLGTTIVATLGMLGIVAAAF
LGQHMHWKTAYLTGGFMGLALLFARFKVSESELFSKKMDPARANPLLLLTGGRFIKYICCILIGVPIYFTTGILFTFAPE
LTAGLNVQGTVTAGNAILYGSIGLTLGDLLAGVFSQWLKSRKRAVAMNLTAGFVLMLVYGLTPGLTSTMVYGLSFLIGIT
VGYWAVLVTMAAEQFGTNIRGTVATTVPNFVRGSAALAASGFAYLKGEMSVSTAALIVGSICFGLALLALTRLEETFHRD
LDYEETANGPQPAAQPSQSGT

Specific function: Could Be A Transporter For 3-Phenylpropionate (Hydrocinnamic Acid). [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081723, Length=170, Percent_Identity=32.9411764705882, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI87082231, Length=248, Percent_Identity=28.2258064516129, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082404, Length=179, Percent_Identity=29.608938547486, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 44628; Mature: 44628

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLRELRSVLNLTVLVAGLGYFVDLFDITLFGVVRVASLKDIGVTDPADILQSGLLIYN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCHHHHH
AQMVGMMVGGLLWGVLADKRGRLSVMFGSILLYSFANLANAFAWDVTSYAVLRFLGGVGL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
AGELGAAITLVAESLPKEKRGLGTTIVATLGMLGIVAAAFLGQHMHWKTAYLTGGFMGLA
CHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LLFARFKVSESELFSKKMDPARANPLLLLTGGRFIKYICCILIGVPIYFTTGILFTFAPE
HHHHHHCCCHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LTAGLNVQGTVTAGNAILYGSIGLTLGDLLAGVFSQWLKSRKRAVAMNLTAGFVLMLVYG
HHCCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHH
LTPGLTSTMVYGLSFLIGITVGYWAVLVTMAAEQFGTNIRGTVATTVPNFVRGSAALAAS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCHHHHCCCHHHHHC
GFAYLKGEMSVSTAALIVGSICFGLALLALTRLEETFHRDLDYEETANGPQPAAQPSQSG
CHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCC
T
C
>Mature Secondary Structure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C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 8011666; 9384377 [H]