Click here to switch to the map view.

The map label for this gene is pyc [H]

Identifier: 108757385

GI number: 108757385

Start: 4662839

End: 4666333

Strand: Direct

Name: pyc [H]

Synonym: MXAN_3881

Alternate gene names: 108757385

Gene position: 4662839-4666333 (Clockwise)

Preceding gene: 108763885

Following gene: 108762585

Centisome position: 51.02

GC content: 69.61

Gene sequence:

>3495_bases
GTGTCGCTGCGTCCCATCCAGAAGGTCCTCTGCGCCAACCGCGGTGAGATTGCCATTCGCGTCTTCCGCGCGTGCAACGA
GTTGGGCATCCGCACCGTCGCCATCTACAGCGACGAGGACCGCACCCACGAGCACCGCCACAAGGCCGACGAGGCGTACC
TCGTGGGCCGGGGCAAGCGGCCCGTGGAGGCCTACCTGGGCATCGACGAAATCCTCGACGTGGCCGTGAAGGCGGGCGTG
GACGCCATCCACCCCGGCTACGGCTTCCTGTCGGAGAACGCCGCCTTCGCGGAGGCGTGTGAGCGGCGTGGCATCCGCTT
CATCGGCCCGCGCTCGGACGTGGTCCGCACCATGGGCGACAAGGTCGCCGCCAAGCACCTGGCCGACGCGTGCGGCGTCC
CGGTGGTTCCCGGCATCACCCTGGAGGGCGACGACGCGCACGTGCTGGAGCAGGCCCGTGCCTTCTTCGCGAAGCAGGGT
GGCCCCATCCTGGTGAAGGCGGCCCATGGCGGCGGCGGCCGAGGCATGCGCGTGGTGCGCGAGGCGAAGGCGCTGGAGGA
TGCGCTGGCCTCCGCGCGTTCGGAGGCGAAGAGCGCCTTCGGTTCGTCGTCGGTGTTCCTGGAGCGCTTCCTGGAGCACG
TGCGCCACATCGAGGTACAGCTACTGGGAGATTTGCACGGCAACATCGTCCACCTGCACGAACGGGACTGCTCCGTGCAG
CGGCGCCATCAGAAGGTCATTGAGATTGCCCCCGCGCCCAATCTGGCCCCGGCGGTGAAGGAGGCCATCTGCGACGCGGC
GGTGCGGCTGGCGCGCAAGGCCGGCTACACCAGCGCTGGCACCGCCGAGTTCCTGGTGGCGGGTGACGCCTTCTACTTCA
TCGAGTGCAATGCCCGCCTCCAGGTGGAGCACACCGTCACCGAGCAGGTGACGGGCGTGGACCTGGTGCAGAGCCAGCTT
CGCATCGCGGAGGGCTTCCGGCTGGACGCGCCGGAGGTGGGCATCTCCCGGCAGGAGGACGTGGTGCCCCGGGGCTACGC
GGTGCAACTGCGCGTCACCACCGAGGACCCTGCCAACCAGTTCATGCCCGACGCGGGCGTCATCACCGCCTGGCGCGCGG
CCACGGGCTTCGGCATCCGGCTGGACGGCTCCAACGGCTACACCAACGCCGTCATCTCCCCCTACTACGACTCCATGCTG
GTGAAGGTCATCGCCTACGCGCCCACGTTCCAGGGCGCGGTGATGAAGGGCCAGCGCGCGCTGCGCGAGTTCCGCATCCG
CGGCGTGAAGACGAACCTGCCCTTCCTGGAGAACGTGCTCGCCCACCCCGCCTTCCAGCAGGGAGAGACGTACACGCGCT
TCATCGACGAGACGCCGGTGCTGTTCCAGTTGGAGCCCCGCAGGGACAGGGCCACCAAGCTGCTCCAGTACCTGGGCGAC
GTCATCGTCAACGGGCACCCCACCATCAAGAAGGACCAGCGGCTCAAGCCCACGCAGTTCCTGGAGCCGCGGCTGCCGGT
GACGCCTTCGGGCCCGGTGCCTCGGGGCACCGCGCACATCCTGGCGGAGAAGGGCCCGCGCGGACTGGCGGACTGGGTGC
TGGCCCAGAAGCGCGTGCTGCTGACGGACACCACCATGCGGGACGCGCACCAGTCCCTGCTGGCCACGCGCATGCGCACG
CGGGACATCCTCCGCGTGGCCCCGGCCACCGCCCACCTGGCCTCCGAGCTGTTCAGCCTGGAGAGCTGGGGCGGCGCCAC
CTTCGACACCACCTACCGCTTCCTCAACGAGGACCCGTGGGCCCGCCTGCGCGCGCTCAAGGCCGCAGCCCCCAACCTGC
TCCAACAGATGCTCCTGCGCGGGGCCAACGCCGTGGGCTACACCAGCTACCCGGACAACGTGGTGGAGGCCTTCATCGAC
GAGGCGGCCGAGGCGGGGGTGGACGTGTTCCGCATCTTCGACAGCCTCAATGATCTGGGCAGCATGGAGGTCTCCACCCG
CCGCGTGCTGACGACGGGCAAGGTGGCGGAGGTGTCCATCTGCTACACGGGCGACGTCGCCAACCCCAAGCGCACGAAGT
ACACGCTGGACTATTACGCGGACCTCGCGAAGCGGATTGAAGACTCCGGCGCGCACTTCCTCTGCATCAAGGACATGGCG
GGCCTCTTGCGCCCGCGCGCGGCGGCCATGCTGGTGCGGCGTCTGCGCGAGGTGACGCGCCTGCCCATCCACCTGCACAT
GCACGACACCTCCGGCAATGGCATCGCCAGCTACCTGGAAGCCATCGAGCAGGGCGTGCACGTGGTGGACGTGGCCCTGG
GCAGCATGGCGGGCCTGACGAGCCAGCCCAGCCTCAACGCGCTGGTCAGCGCCCTGCGCGGCCACCCCCGTGAGACGGGC
CTGGCCAACGCGCGCCTTCAGCCGCTGGCCAACTACTGGGAGGACGTGCGCGAGTACTACGCCCCCTTCGAGGCCGGCCT
CAAGAGCACCACCAGCGAGGTGTACTACCACGAGATTCCTGGCGGCCAGTATTCCAACCTCCGGCCGCAGGTGGCGGAAC
TGGGCCTGCTGGGCCGGTGGAACGACGTGAAGGACGCCTTCGCGCTCGTGAACGTCCTGGTGGGCGACATCCCGAAGGTG
ACGCCGTCGTCGAAGATGGTCGGCGACTTCGCCATCTTCCTGCTCAAGAACGACCTCACGGTGCGCGCCTCCACGCTGGC
GGAGGCGGCCTCGCTCACGCGCCAGAGGCTGATTGAACAGGCGCCGCGCCTGGACTTCCCCACCAGCGTGGTGGGCTACT
TCCGAGGTGAGCTGGGCCAGCCGCCCAACGGCTTCCCCGAGGACCTGCGCGCCGCCGTGCTCAAGGGCCTGCCCCGCGTG
GAGGGACGGCCCTCCGCCAGCCTGCCGCCGCTGGACCTGGACGCGCTCCAGCGGGAGCTCTCCGCGAAGACAGGACATGC
GCTCACCCGCGTGGACGCCATCTCCAGCGCGCTCTATCCGCGCGTCATCGCCGGCTACCTGGAAGACCTGGGGCGCTACG
AGGACGTGTCCATCCTCGACACCCCGAACTACTTCTACGGCATGGAGGTGGGACAGGAGGTCTGGGTGGACCTGGAGCCG
GGCAAGACGCTGGTCATCAGCCTGTCCGCGGTGGGCGAGCCGGATGAAGAGGGCGTGCGCACCGTCTACTTCGCCCTCAA
CGGCCACACCCGCACCGTGCACGTGAGGGACCGCAGCCGCGCCGCCACCGTGGAGACGCGGCGTCAGGCGGACCGCGCCA
ATCCCAGCCACGTCGCGGCGAGCATGCCGGGCACCGTCATCGCCCTTCATGCCAAATCGGGAGACGCCGTGGAGGCGGGC
GCGCCCCTCGTCACCCTCGAGGCGATGAAGATGGAGACGGTGGTGCGGGCCCCGCGCGCCGGCACCGTGGCGGAGGTCGT
CCCCGCGCTCAAGGCCTCCGTCCAGGGCGGAGACCTGCTGGCGGTGCTCCAGTGA

Upstream 100 bases:

>100_bases
GGCGCGGCGCTCACGGGGCGCCGCGCTTTGAATCGGACGTTCGCCCCGGCAGCCGTTGCTCCGGGGCCGACGGGATGCAT
ACAGCGCGCACATGGAACAT

Downstream 100 bases:

>100_bases
CGGAGGGACCGGCCCCTCAGAAGGTCACCGTCATCACCACGGTGTCCGCATAGGCCCCCGCGGGGATGGCCTGTCCGGCC
GGGATGCGCCCGAAGATGGG

Product: pyruvate carboxylase

Products: NA

Alternate protein names: Pyruvic carboxylase; PYC [H]

Number of amino acids: Translated: 1164; Mature: 1163

Protein sequence:

>1164_residues
MSLRPIQKVLCANRGEIAIRVFRACNELGIRTVAIYSDEDRTHEHRHKADEAYLVGRGKRPVEAYLGIDEILDVAVKAGV
DAIHPGYGFLSENAAFAEACERRGIRFIGPRSDVVRTMGDKVAAKHLADACGVPVVPGITLEGDDAHVLEQARAFFAKQG
GPILVKAAHGGGGRGMRVVREAKALEDALASARSEAKSAFGSSSVFLERFLEHVRHIEVQLLGDLHGNIVHLHERDCSVQ
RRHQKVIEIAPAPNLAPAVKEAICDAAVRLARKAGYTSAGTAEFLVAGDAFYFIECNARLQVEHTVTEQVTGVDLVQSQL
RIAEGFRLDAPEVGISRQEDVVPRGYAVQLRVTTEDPANQFMPDAGVITAWRAATGFGIRLDGSNGYTNAVISPYYDSML
VKVIAYAPTFQGAVMKGQRALREFRIRGVKTNLPFLENVLAHPAFQQGETYTRFIDETPVLFQLEPRRDRATKLLQYLGD
VIVNGHPTIKKDQRLKPTQFLEPRLPVTPSGPVPRGTAHILAEKGPRGLADWVLAQKRVLLTDTTMRDAHQSLLATRMRT
RDILRVAPATAHLASELFSLESWGGATFDTTYRFLNEDPWARLRALKAAAPNLLQQMLLRGANAVGYTSYPDNVVEAFID
EAAEAGVDVFRIFDSLNDLGSMEVSTRRVLTTGKVAEVSICYTGDVANPKRTKYTLDYYADLAKRIEDSGAHFLCIKDMA
GLLRPRAAAMLVRRLREVTRLPIHLHMHDTSGNGIASYLEAIEQGVHVVDVALGSMAGLTSQPSLNALVSALRGHPRETG
LANARLQPLANYWEDVREYYAPFEAGLKSTTSEVYYHEIPGGQYSNLRPQVAELGLLGRWNDVKDAFALVNVLVGDIPKV
TPSSKMVGDFAIFLLKNDLTVRASTLAEAASLTRQRLIEQAPRLDFPTSVVGYFRGELGQPPNGFPEDLRAAVLKGLPRV
EGRPSASLPPLDLDALQRELSAKTGHALTRVDAISSALYPRVIAGYLEDLGRYEDVSILDTPNYFYGMEVGQEVWVDLEP
GKTLVISLSAVGEPDEEGVRTVYFALNGHTRTVHVRDRSRAATVETRRQADRANPSHVAASMPGTVIALHAKSGDAVEAG
APLVTLEAMKMETVVRAPRAGTVAEVVPALKASVQGGDLLAVLQ

Sequences:

>Translated_1164_residues
MSLRPIQKVLCANRGEIAIRVFRACNELGIRTVAIYSDEDRTHEHRHKADEAYLVGRGKRPVEAYLGIDEILDVAVKAGV
DAIHPGYGFLSENAAFAEACERRGIRFIGPRSDVVRTMGDKVAAKHLADACGVPVVPGITLEGDDAHVLEQARAFFAKQG
GPILVKAAHGGGGRGMRVVREAKALEDALASARSEAKSAFGSSSVFLERFLEHVRHIEVQLLGDLHGNIVHLHERDCSVQ
RRHQKVIEIAPAPNLAPAVKEAICDAAVRLARKAGYTSAGTAEFLVAGDAFYFIECNARLQVEHTVTEQVTGVDLVQSQL
RIAEGFRLDAPEVGISRQEDVVPRGYAVQLRVTTEDPANQFMPDAGVITAWRAATGFGIRLDGSNGYTNAVISPYYDSML
VKVIAYAPTFQGAVMKGQRALREFRIRGVKTNLPFLENVLAHPAFQQGETYTRFIDETPVLFQLEPRRDRATKLLQYLGD
VIVNGHPTIKKDQRLKPTQFLEPRLPVTPSGPVPRGTAHILAEKGPRGLADWVLAQKRVLLTDTTMRDAHQSLLATRMRT
RDILRVAPATAHLASELFSLESWGGATFDTTYRFLNEDPWARLRALKAAAPNLLQQMLLRGANAVGYTSYPDNVVEAFID
EAAEAGVDVFRIFDSLNDLGSMEVSTRRVLTTGKVAEVSICYTGDVANPKRTKYTLDYYADLAKRIEDSGAHFLCIKDMA
GLLRPRAAAMLVRRLREVTRLPIHLHMHDTSGNGIASYLEAIEQGVHVVDVALGSMAGLTSQPSLNALVSALRGHPRETG
LANARLQPLANYWEDVREYYAPFEAGLKSTTSEVYYHEIPGGQYSNLRPQVAELGLLGRWNDVKDAFALVNVLVGDIPKV
TPSSKMVGDFAIFLLKNDLTVRASTLAEAASLTRQRLIEQAPRLDFPTSVVGYFRGELGQPPNGFPEDLRAAVLKGLPRV
EGRPSASLPPLDLDALQRELSAKTGHALTRVDAISSALYPRVIAGYLEDLGRYEDVSILDTPNYFYGMEVGQEVWVDLEP
GKTLVISLSAVGEPDEEGVRTVYFALNGHTRTVHVRDRSRAATVETRRQADRANPSHVAASMPGTVIALHAKSGDAVEAG
APLVTLEAMKMETVVRAPRAGTVAEVVPALKASVQGGDLLAVLQ
>Mature_1163_residues
SLRPIQKVLCANRGEIAIRVFRACNELGIRTVAIYSDEDRTHEHRHKADEAYLVGRGKRPVEAYLGIDEILDVAVKAGVD
AIHPGYGFLSENAAFAEACERRGIRFIGPRSDVVRTMGDKVAAKHLADACGVPVVPGITLEGDDAHVLEQARAFFAKQGG
PILVKAAHGGGGRGMRVVREAKALEDALASARSEAKSAFGSSSVFLERFLEHVRHIEVQLLGDLHGNIVHLHERDCSVQR
RHQKVIEIAPAPNLAPAVKEAICDAAVRLARKAGYTSAGTAEFLVAGDAFYFIECNARLQVEHTVTEQVTGVDLVQSQLR
IAEGFRLDAPEVGISRQEDVVPRGYAVQLRVTTEDPANQFMPDAGVITAWRAATGFGIRLDGSNGYTNAVISPYYDSMLV
KVIAYAPTFQGAVMKGQRALREFRIRGVKTNLPFLENVLAHPAFQQGETYTRFIDETPVLFQLEPRRDRATKLLQYLGDV
IVNGHPTIKKDQRLKPTQFLEPRLPVTPSGPVPRGTAHILAEKGPRGLADWVLAQKRVLLTDTTMRDAHQSLLATRMRTR
DILRVAPATAHLASELFSLESWGGATFDTTYRFLNEDPWARLRALKAAAPNLLQQMLLRGANAVGYTSYPDNVVEAFIDE
AAEAGVDVFRIFDSLNDLGSMEVSTRRVLTTGKVAEVSICYTGDVANPKRTKYTLDYYADLAKRIEDSGAHFLCIKDMAG
LLRPRAAAMLVRRLREVTRLPIHLHMHDTSGNGIASYLEAIEQGVHVVDVALGSMAGLTSQPSLNALVSALRGHPRETGL
ANARLQPLANYWEDVREYYAPFEAGLKSTTSEVYYHEIPGGQYSNLRPQVAELGLLGRWNDVKDAFALVNVLVGDIPKVT
PSSKMVGDFAIFLLKNDLTVRASTLAEAASLTRQRLIEQAPRLDFPTSVVGYFRGELGQPPNGFPEDLRAAVLKGLPRVE
GRPSASLPPLDLDALQRELSAKTGHALTRVDAISSALYPRVIAGYLEDLGRYEDVSILDTPNYFYGMEVGQEVWVDLEPG
KTLVISLSAVGEPDEEGVRTVYFALNGHTRTVHVRDRSRAATVETRRQADRANPSHVAASMPGTVIALHAKSGDAVEAGA
PLVTLEAMKMETVVRAPRAGTVAEVVPALKASVQGGDLLAVLQ

Specific function: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second, leading to oxaloacetate production. Fulfills an anaplerotic functi

COG id: COG1038

COG function: function code C; Pyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI106049528, Length=1166, Percent_Identity=51.3722126929674, Blast_Score=1107, Evalue=0.0,
Organism=Homo sapiens, GI106049295, Length=1166, Percent_Identity=51.3722126929674, Blast_Score=1107, Evalue=0.0,
Organism=Homo sapiens, GI106049292, Length=1166, Percent_Identity=51.3722126929674, Blast_Score=1107, Evalue=0.0,
Organism=Homo sapiens, GI116805327, Length=459, Percent_Identity=44.880174291939, Blast_Score=382, Evalue=1e-105,
Organism=Homo sapiens, GI189095269, Length=459, Percent_Identity=41.3943355119826, Blast_Score=328, Evalue=2e-89,
Organism=Homo sapiens, GI65506442, Length=457, Percent_Identity=41.3566739606127, Blast_Score=326, Evalue=1e-88,
Organism=Homo sapiens, GI295821183, Length=457, Percent_Identity=41.3566739606127, Blast_Score=325, Evalue=2e-88,
Organism=Homo sapiens, GI38679977, Length=506, Percent_Identity=31.8181818181818, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679967, Length=506, Percent_Identity=31.8181818181818, Blast_Score=232, Evalue=1e-60,
Organism=Homo sapiens, GI38679960, Length=506, Percent_Identity=31.8181818181818, Blast_Score=232, Evalue=2e-60,
Organism=Homo sapiens, GI38679971, Length=506, Percent_Identity=31.8181818181818, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI38679974, Length=506, Percent_Identity=31.8181818181818, Blast_Score=231, Evalue=2e-60,
Organism=Homo sapiens, GI134142062, Length=506, Percent_Identity=32.0158102766798, Blast_Score=227, Evalue=6e-59,
Organism=Escherichia coli, GI1789654, Length=453, Percent_Identity=46.1368653421634, Blast_Score=366, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17562816, Length=1162, Percent_Identity=50.2581755593804, Blast_Score=1084, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987519, Length=464, Percent_Identity=45.2586206896552, Blast_Score=363, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI17567343, Length=499, Percent_Identity=39.0781563126253, Blast_Score=318, Evalue=2e-86,
Organism=Caenorhabditis elegans, GI133931226, Length=493, Percent_Identity=30.2231237322515, Blast_Score=197, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71997168, Length=347, Percent_Identity=36.5994236311239, Blast_Score=192, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI71997163, Length=347, Percent_Identity=36.5994236311239, Blast_Score=192, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6321376, Length=1175, Percent_Identity=47.7446808510638, Blast_Score=1012, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=1177, Percent_Identity=47.6635514018692, Blast_Score=1009, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319685, Length=507, Percent_Identity=37.67258382643, Blast_Score=322, Evalue=2e-88,
Organism=Saccharomyces cerevisiae, GI6324343, Length=515, Percent_Identity=31.4563106796116, Blast_Score=224, Evalue=9e-59,
Organism=Saccharomyces cerevisiae, GI6323863, Length=487, Percent_Identity=32.2381930184805, Blast_Score=219, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6322331, Length=316, Percent_Identity=20.8860759493671, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24652212, Length=1170, Percent_Identity=51.8803418803419, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652210, Length=1170, Percent_Identity=51.8803418803419, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652214, Length=1170, Percent_Identity=51.8803418803419, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI19921944, Length=1170, Percent_Identity=51.8803418803419, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652216, Length=1170, Percent_Identity=51.8803418803419, Blast_Score=1144, Evalue=0.0,
Organism=Drosophila melanogaster, GI281363050, Length=1186, Percent_Identity=51.1804384485666, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652224, Length=1186, Percent_Identity=51.1804384485666, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652222, Length=1186, Percent_Identity=51.1804384485666, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652220, Length=1186, Percent_Identity=51.1804384485666, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24652218, Length=1186, Percent_Identity=51.1804384485666, Blast_Score=1139, Evalue=0.0,
Organism=Drosophila melanogaster, GI24651757, Length=458, Percent_Identity=43.2314410480349, Blast_Score=361, Evalue=2e-99,
Organism=Drosophila melanogaster, GI24651759, Length=416, Percent_Identity=41.8269230769231, Blast_Score=313, Evalue=5e-85,
Organism=Drosophila melanogaster, GI24586458, Length=503, Percent_Identity=31.610337972167, Blast_Score=209, Evalue=1e-53,
Organism=Drosophila melanogaster, GI161076407, Length=503, Percent_Identity=31.610337972167, Blast_Score=209, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24586460, Length=503, Percent_Identity=31.610337972167, Blast_Score=209, Evalue=1e-53,
Organism=Drosophila melanogaster, GI161076409, Length=503, Percent_Identity=31.610337972167, Blast_Score=209, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR000089
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR003379
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR000891
- InterPro:   IPR005930
- InterPro:   IPR011054
- InterPro:   IPR011053 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00364 Biotin_lipoyl; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2; PF00682 HMGL-like; PF02436 PYC_OADA [H]

EC number: =6.4.1.1 [H]

Molecular weight: Translated: 127090; Mature: 126958

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS50975 ATP_GRASP ; PS00867 CPSASE_2 ; PS50979 BC ; PS50991 PYR_CT ; PS50968 BIOTINYL_LIPOYL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRPIQKVLCANRGEIAIRVFRACNELGIRTVAIYSDEDRTHEHRHKADEAYLVGRGKR
CCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEEEECCCC
PVEAYLGIDEILDVAVKAGVDAIHPGYGFLSENAAFAEACERRGIRFIGPRSDVVRTMGD
CHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCHHHHHHHHHH
KVAAKHLADACGVPVVPGITLEGDDAHVLEQARAFFAKQGGPILVKAAHGGGGRGMRVVR
HHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHH
EAKALEDALASARSEAKSAFGSSSVFLERFLEHVRHIEVQLLGDLHGNIVHLHERDCSVQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHH
RRHQKVIEIAPAPNLAPAVKEAICDAAVRLARKAGYTSAGTAEFLVAGDAFYFIECNARL
HHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEEECCEE
QVEHTVTEQVTGVDLVQSQLRIAEGFRLDAPEVGISRQEDVVPRGYAVQLRVTTEDPANQ
EEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
FMPDAGVITAWRAATGFGIRLDGSNGYTNAVISPYYDSMLVKVIAYAPTFQGAVMKGQRA
CCCCCCCEEEEHHCCCCEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHH
LREFRIRGVKTNLPFLENVLAHPAFQQGETYTRFIDETPVLFQLEPRRDRATKLLQYLGD
HHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
VIVNGHPTIKKDQRLKPTQFLEPRLPVTPSGPVPRGTAHILAEKGPRGLADWVLAQKRVL
HEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHEECCCCCCHHHHHHHCCCEE
LTDTTMRDAHQSLLATRMRTRDILRVAPATAHLASELFSLESWGGATFDTTYRFLNEDPW
EECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
ARLRALKAAAPNLLQQMLLRGANAVGYTSYPDNVVEAFIDEAAEAGVDVFRIFDSLNDLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
SMEVSTRRVLTTGKVAEVSICYTGDVANPKRTKYTLDYYADLAKRIEDSGAHFLCIKDMA
CCCCCHHHEEECCCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEHHHHH
GLLRPRAAAMLVRRLREVTRLPIHLHMHDTSGNGIASYLEAIEQGVHVVDVALGSMAGLT
HHHCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHHCCCC
SQPSLNALVSALRGHPRETGLANARLQPLANYWEDVREYYAPFEAGLKSTTSEVYYHEIP
CCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECC
GGQYSNLRPQVAELGLLGRWNDVKDAFALVNVLVGDIPKVTPSSKMVGDFAIFLLKNDLT
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEEEEECCCE
VRASTLAEAASLTRQRLIEQAPRLDFPTSVVGYFRGELGQPPNGFPEDLRAAVLKGLPRV
EEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
EGRPSASLPPLDLDALQRELSAKTGHALTRVDAISSALYPRVIAGYLEDLGRYEDVSILD
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TPNYFYGMEVGQEVWVDLEPGKTLVISLSAVGEPDEEGVRTVYFALNGHTRTVHVRDRSR
CCCCEEECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEECCCCC
AATVETRRQADRANPSHVAASMPGTVIALHAKSGDAVEAGAPLVTLEAMKMETVVRAPRA
HHHHHHHHHHCCCCHHHEEECCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHCCCC
GTVAEVVPALKASVQGGDLLAVLQ
CHHHHHHHHHHHCCCCCCEEEEEC
>Mature Secondary Structure 
SLRPIQKVLCANRGEIAIRVFRACNELGIRTVAIYSDEDRTHEHRHKADEAYLVGRGKR
CCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCEEEEECCCC
PVEAYLGIDEILDVAVKAGVDAIHPGYGFLSENAAFAEACERRGIRFIGPRSDVVRTMGD
CHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHCCCEEECCHHHHHHHHHH
KVAAKHLADACGVPVVPGITLEGDDAHVLEQARAFFAKQGGPILVKAAHGGGGRGMRVVR
HHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHH
EAKALEDALASARSEAKSAFGSSSVFLERFLEHVRHIEVQLLGDLHGNIVHLHERDCSVQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHH
RRHQKVIEIAPAPNLAPAVKEAICDAAVRLARKAGYTSAGTAEFLVAGDAFYFIECNARL
HHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEEEEECCEE
QVEHTVTEQVTGVDLVQSQLRIAEGFRLDAPEVGISRQEDVVPRGYAVQLRVTTEDPANQ
EEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
FMPDAGVITAWRAATGFGIRLDGSNGYTNAVISPYYDSMLVKVIAYAPTFQGAVMKGQRA
CCCCCCCEEEEHHCCCCEEEEECCCCCCCCEECHHHHHHHHHHHHHCCCCCHHHHHHHHH
LREFRIRGVKTNLPFLENVLAHPAFQQGETYTRFIDETPVLFQLEPRRDRATKLLQYLGD
HHHHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHCCCCEEEEECCCHHHHHHHHHHHHH
VIVNGHPTIKKDQRLKPTQFLEPRLPVTPSGPVPRGTAHILAEKGPRGLADWVLAQKRVL
HEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCHHHHEECCCCCCHHHHHHHCCCEE
LTDTTMRDAHQSLLATRMRTRDILRVAPATAHLASELFSLESWGGATFDTTYRFLNEDPW
EECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHH
ARLRALKAAAPNLLQQMLLRGANAVGYTSYPDNVVEAFIDEAAEAGVDVFRIFDSLNDLG
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
SMEVSTRRVLTTGKVAEVSICYTGDVANPKRTKYTLDYYADLAKRIEDSGAHFLCIKDMA
CCCCCHHHEEECCCEEEEEEEEECCCCCCCCCEEEHHHHHHHHHHHHCCCCEEEEHHHHH
GLLRPRAAAMLVRRLREVTRLPIHLHMHDTSGNGIASYLEAIEQGVHVVDVALGSMAGLT
HHHCHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCEEEEHHHHHHCCCC
SQPSLNALVSALRGHPRETGLANARLQPLANYWEDVREYYAPFEAGLKSTTSEVYYHEIP
CCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEEEEECC
GGQYSNLRPQVAELGLLGRWNDVKDAFALVNVLVGDIPKVTPSSKMVGDFAIFLLKNDLT
CCCCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHEEEEEEECCCE
VRASTLAEAASLTRQRLIEQAPRLDFPTSVVGYFRGELGQPPNGFPEDLRAAVLKGLPRV
EEHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
EGRPSASLPPLDLDALQRELSAKTGHALTRVDAISSALYPRVIAGYLEDLGRYEDVSILD
CCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
TPNYFYGMEVGQEVWVDLEPGKTLVISLSAVGEPDEEGVRTVYFALNGHTRTVHVRDRSR
CCCCEEECCCCCEEEEEECCCCEEEEEEECCCCCCCCCCEEEEEEECCCEEEEEECCCCC
AATVETRRQADRANPSHVAASMPGTVIALHAKSGDAVEAGAPLVTLEAMKMETVVRAPRA
HHHHHHHHHHCCCCHHHEEECCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHCCCC
GTVAEVVPALKASVQGGDLLAVLQ
CHHHHHHHHHHHCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]