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The map label for this gene is ubiB [C]

Identifier: 108763857

GI number: 108763857

Start: 827854

End: 829158

Strand: Direct

Name: ubiB [C]

Synonym: MXAN_0725

Alternate gene names: 108763857

Gene position: 827854-829158 (Clockwise)

Preceding gene: 108761219

Following gene: 108759757

Centisome position: 9.06

GC content: 69.27

Gene sequence:

>1305_bases
ATGGCCTCCGACCCCGACGACAAGCTTCCTCCCCAGGGCCGCTTCAACCGCCTGCGCAAGCTGGCAGGCCTCTCCGTGCA
GGTGGGCACGGATGTGCTCAAGAGCGGCGCGAAGCGCCTGTCCGGGAGCACGCCCGACCTGCTCAGCAAGGAGGCCGCGG
AGAAGCTGGTCTCCACCCTGGGCGAGCTCAAGGGGGCCGCCATGAAGATGGGACAGGCCATCTCCATGGACCCGGACCTG
CTCACCCCCGAGGTGCGGCAGGTGCTGGCGCGGCTGCAGAACCAGGCGCCCTCCATGTCCTACGCGCAGGTGTCGCGCGT
GGTCCAGGCGGAGCTGGGCGCGCCGCCGGAGTCGCTCTTCCGCGAGTTCAGCGAGGAGCCGTTGGCGGCCGCGTCGCTGG
GGCAGGTGCACCGCGCGGTGCTGGAGGACGGCCGGGCGGTGGCGGTGAAGGTGCAATACCCCGGCATCGACGTGTCCCTG
GCCAACGACATGGCGAACCTGGGCATCGTGGCGAAGACGGCGTCGACGGTGCTGCGCGTGTCCGATGCAGGCGCCTACTT
CCAGGAGTTCCGCGACGAGATGCTGCTGGAGTTGGACTACCACCGCGAGGCCGAGCTGGCCGAGGGCTTCGCGCGCAGCG
TGGCGAAGCTGCCGGAGCTGTGTGTGCCCGCCGTCATCTCCAGCCACAGCGCGAAGCGGGTGCTGACGCTGGAGCTGCTG
GAGGGGCTCACCCTCAAGGACTGGCTGCCGACGAATCCCTCCAACGAGGCGCGCTTCCGCGTGGCGCGCCAGCTCATCCT
CGCCACCTACGGGCCCTTCTTCGGCGCGGGCGAAATCCACGCGGACCCGCACCCGGGCAACTTCATGGTGATGCCGGACG
GGCGGCTGGGCTTGCTGGACTTCGGCTCCATCAAGCGCTTCTCCCCGCGCTTCGTGGACGTCAACCAGCGCATGCTCCGG
CAGACGATGCGCATGGAGCCGTTGGACATCCTGAGCCTGAGCCGGGAGGTGGGCTTCACCGTGGAGCTTCCGGACGACGA
GGCCGAGGACCTCATCACCGAGGTGCTGCGCATCGCCGGGCGGCCCATGCGCCTGCCGGACTACGACTACGCGGTCTGCG
AAATCAACCGCGACATGCGCCACCACTTCTCGCGCAACGCGCCGCGCTTCCTGAAAATCAGGCCGCCACCGGAGGCGATG
ATGTTCTTCCGCTCCACCGGTGGGCTGGCGCAGAACCTGAGGCTCATCGGCGCGCGGGGGGACTTCCGCGCGGTCTTCCT
GGAAGTGACGGACCTGCCCGCGTGA

Upstream 100 bases:

>100_bases
GGGGCCGCGCCCGCCTCCAGGTAGGGCGGCCTGGCTGTCTCGGCGGGGCGTCATGCCTTGCGTCTGGCGGGGCCCTCCTC
GTTAATCCACTTCAGCTCCC

Downstream 100 bases:

>100_bases
GGCCGGCGCCGCGCTAACGCGCGGCCTGCACGGCTTCCGAAGCCGCGGGCTTGAGGTGGAGCGCTTCCAGCCGCTGGGCC
AGCTCCTCGCCCTGCACGCT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MASDPDDKLPPQGRFNRLRKLAGLSVQVGTDVLKSGAKRLSGSTPDLLSKEAAEKLVSTLGELKGAAMKMGQAISMDPDL
LTPEVRQVLARLQNQAPSMSYAQVSRVVQAELGAPPESLFREFSEEPLAAASLGQVHRAVLEDGRAVAVKVQYPGIDVSL
ANDMANLGIVAKTASTVLRVSDAGAYFQEFRDEMLLELDYHREAELAEGFARSVAKLPELCVPAVISSHSAKRVLTLELL
EGLTLKDWLPTNPSNEARFRVARQLILATYGPFFGAGEIHADPHPGNFMVMPDGRLGLLDFGSIKRFSPRFVDVNQRMLR
QTMRMEPLDILSLSREVGFTVELPDDEAEDLITEVLRIAGRPMRLPDYDYAVCEINRDMRHHFSRNAPRFLKIRPPPEAM
MFFRSTGGLAQNLRLIGARGDFRAVFLEVTDLPA

Sequences:

>Translated_434_residues
MASDPDDKLPPQGRFNRLRKLAGLSVQVGTDVLKSGAKRLSGSTPDLLSKEAAEKLVSTLGELKGAAMKMGQAISMDPDL
LTPEVRQVLARLQNQAPSMSYAQVSRVVQAELGAPPESLFREFSEEPLAAASLGQVHRAVLEDGRAVAVKVQYPGIDVSL
ANDMANLGIVAKTASTVLRVSDAGAYFQEFRDEMLLELDYHREAELAEGFARSVAKLPELCVPAVISSHSAKRVLTLELL
EGLTLKDWLPTNPSNEARFRVARQLILATYGPFFGAGEIHADPHPGNFMVMPDGRLGLLDFGSIKRFSPRFVDVNQRMLR
QTMRMEPLDILSLSREVGFTVELPDDEAEDLITEVLRIAGRPMRLPDYDYAVCEINRDMRHHFSRNAPRFLKIRPPPEAM
MFFRSTGGLAQNLRLIGARGDFRAVFLEVTDLPA
>Mature_433_residues
ASDPDDKLPPQGRFNRLRKLAGLSVQVGTDVLKSGAKRLSGSTPDLLSKEAAEKLVSTLGELKGAAMKMGQAISMDPDLL
TPEVRQVLARLQNQAPSMSYAQVSRVVQAELGAPPESLFREFSEEPLAAASLGQVHRAVLEDGRAVAVKVQYPGIDVSLA
NDMANLGIVAKTASTVLRVSDAGAYFQEFRDEMLLELDYHREAELAEGFARSVAKLPELCVPAVISSHSAKRVLTLELLE
GLTLKDWLPTNPSNEARFRVARQLILATYGPFFGAGEIHADPHPGNFMVMPDGRLGLLDFGSIKRFSPRFVDVNQRMLRQ
TMRMEPLDILSLSREVGFTVELPDDEAEDLITEVLRIAGRPMRLPDYDYAVCEINRDMRHHFSRNAPRFLKIRPPPEAMM
FFRSTGGLAQNLRLIGARGDFRAVFLEVTDLPA

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI27363457, Length=361, Percent_Identity=32.1329639889197, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI34147522, Length=433, Percent_Identity=28.175519630485, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI217416386, Length=332, Percent_Identity=30.421686746988, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI41393593, Length=300, Percent_Identity=34, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI40254938, Length=281, Percent_Identity=29.8932384341637, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI217035081, Length=222, Percent_Identity=30.1801801801802, Blast_Score=91, Evalue=2e-18,
Organism=Escherichia coli, GI2367309, Length=249, Percent_Identity=28.1124497991968, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI32565180, Length=373, Percent_Identity=31.6353887399464, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17559152, Length=258, Percent_Identity=34.1085271317829, Blast_Score=119, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321319, Length=435, Percent_Identity=26.8965517241379, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323282, Length=240, Percent_Identity=30.4166666666667, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18859849, Length=380, Percent_Identity=32.6315789473684, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24662575, Length=300, Percent_Identity=32, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI22024280, Length=270, Percent_Identity=32.962962962963, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 47907; Mature: 47776

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASDPDDKLPPQGRFNRLRKLAGLSVQVGTDVLKSGAKRLSGSTPDLLSKEAAEKLVSTL
CCCCCCCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GELKGAAMKMGQAISMDPDLLTPEVRQVLARLQNQAPSMSYAQVSRVVQAELGAPPESLF
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHH
REFSEEPLAAASLGQVHRAVLEDGRAVAVKVQYPGIDVSLANDMANLGIVAKTASTVLRV
HHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHCCHHHCCCCEECHHHHEEE
SDAGAYFQEFRDEMLLELDYHREAELAEGFARSVAKLPELCVPAVISSHSAKRVLTLELL
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EGLTLKDWLPTNPSNEARFRVARQLILATYGPFFGAGEIHADPHPGNFMVMPDGRLGLLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEECCCCCCEEE
FGSIKRFSPRFVDVNQRMLRQTMRMEPLDILSLSREVGFTVELPDDEAEDLITEVLRIAG
CCCCCCCCCCEECHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCC
RPMRLPDYDYAVCEINRDMRHHFSRNAPRFLKIRPPPEAMMFFRSTGGLAQNLRLIGARG
CCCCCCCCCEEEEEECHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCHHHCCEEEECCC
DFRAVFLEVTDLPA
CEEEEEEEECCCCC
>Mature Secondary Structure 
ASDPDDKLPPQGRFNRLRKLAGLSVQVGTDVLKSGAKRLSGSTPDLLSKEAAEKLVSTL
CCCCCCCCCCCHHHHHHHHHHCCEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GELKGAAMKMGQAISMDPDLLTPEVRQVLARLQNQAPSMSYAQVSRVVQAELGAPPESLF
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHH
REFSEEPLAAASLGQVHRAVLEDGRAVAVKVQYPGIDVSLANDMANLGIVAKTASTVLRV
HHHCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEHHCCHHHCCCCEECHHHHEEE
SDAGAYFQEFRDEMLLELDYHREAELAEGFARSVAKLPELCVPAVISSHSAKRVLTLELL
CCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EGLTLKDWLPTNPSNEARFRVARQLILATYGPFFGAGEIHADPHPGNFMVMPDGRLGLLD
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCEEEECCCCCCEEE
FGSIKRFSPRFVDVNQRMLRQTMRMEPLDILSLSREVGFTVELPDDEAEDLITEVLRIAG
CCCCCCCCCCEECHHHHHHHHHHCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHCC
RPMRLPDYDYAVCEINRDMRHHFSRNAPRFLKIRPPPEAMMFFRSTGGLAQNLRLIGARG
CCCCCCCCCEEEEEECHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCHHHCCEEEECCC
DFRAVFLEVTDLPA
CEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]