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The map label for this gene is rlmH

Identifier: 108763853

GI number: 108763853

Start: 1452360

End: 1452824

Strand: Reverse

Name: rlmH

Synonym: MXAN_1239

Alternate gene names: 108763853

Gene position: 1452824-1452360 (Counterclockwise)

Preceding gene: 108762788

Following gene: 108757268

Centisome position: 15.9

GC content: 67.96

Gene sequence:

>465_bases
GTGAAGGTCCGGCTCCTCTCCATCGGCAAGGACCGCTCGGGCCTGTATGAGCCCGCGGTCCAGGAGTACGCCAAGCGCCT
GGGCCACTACACCCGCTTCGAGTTGGTGGAGATGGCGGAGGCCAGCGGCAAGCGGCTCAAGCCCGGCGACGCGAAGGCCG
CCGAAGCCGAGGCGATTCTCTCCAAGCGCAAGCCGCAGGACTGGCTGGTGGCCCTGGACGAGCGCGGCTCACTGCTCGAC
TCCGTCGAGCTGAGCCGCTACGTCGGCAAGGCGCAGACGGGCGCCAAGGACCTGCTGTTCATCATTGGCGGGGACGAAGG
GCTCGACGCGCGCGTGCGGGACGCGGCGAACCTCACGCTGTCCCTGTCGAAGATGACGCTGCCTCACCGGCTGGCGCGCG
TGGTGCTCATCGAACAGCTCTACCGCGCGTTCACCATCCTCAAGGGCGAGCCGTACCACAAGTAG

Upstream 100 bases:

>100_bases
TACGGCGAGGTGGTGGCGCACCTGTTCCTCACCGACCTGCGCGCGCACTACGACCTCGAGGGACTCTGGGCCGACGCGTC
TCGGGAGAAGCTGGCCTGAG

Downstream 100 bases:

>100_bases
GCGGCCGGGCACGGGGCCCGGCGCCACCGTCAGGCGTGGCGCGCGGGTGCCGTCAGCCCGGGCATGCGCACTGACGCCTC
CTCTGAACATCTCCCCACTT

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKVRLLSIGKDRSGLYEPAVQEYAKRLGHYTRFELVEMAEASGKRLKPGDAKAAEAEAILSKRKPQDWLVALDERGSLLD
SVELSRYVGKAQTGAKDLLFIIGGDEGLDARVRDAANLTLSLSKMTLPHRLARVVLIEQLYRAFTILKGEPYHK

Sequences:

>Translated_154_residues
MKVRLLSIGKDRSGLYEPAVQEYAKRLGHYTRFELVEMAEASGKRLKPGDAKAAEAEAILSKRKPQDWLVALDERGSLLD
SVELSRYVGKAQTGAKDLLFIIGGDEGLDARVRDAANLTLSLSKMTLPHRLARVVLIEQLYRAFTILKGEPYHK
>Mature_154_residues
MKVRLLSIGKDRSGLYEPAVQEYAKRLGHYTRFELVEMAEASGKRLKPGDAKAAEAEAILSKRKPQDWLVALDERGSLLD
SVELSRYVGKAQTGAKDLLFIIGGDEGLDARVRDAANLTLSLSKMTLPHRLARVVLIEQLYRAFTILKGEPYHK

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=157, Percent_Identity=34.3949044585987, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_MYXXD (Q1DCX5)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629498.1
- ProteinModelPortal:   Q1DCX5
- SMR:   Q1DCX5
- STRING:   Q1DCX5
- GeneID:   4107614
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1239
- TIGR:   MXAN_1239
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- PhylomeDB:   Q1DCX5
- ProtClustDB:   CLSK944912
- BioCyc:   MXAN246197:MXAN_1239-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR003742
- PIRSF:   PIRSF004505

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17180; Mature: 17180

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRLLSIGKDRSGLYEPAVQEYAKRLGHYTRFELVEMAEASGKRLKPGDAKAAEAEAIL
CEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SKRKPQDWLVALDERGSLLDSVELSRYVGKAQTGAKDLLFIIGGDEGLDARVRDAANLTL
HCCCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHCCCEEE
SLSKMTLPHRLARVVLIEQLYRAFTILKGEPYHK
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKVRLLSIGKDRSGLYEPAVQEYAKRLGHYTRFELVEMAEASGKRLKPGDAKAAEAEAIL
CEEEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
SKRKPQDWLVALDERGSLLDSVELSRYVGKAQTGAKDLLFIIGGDEGLDARVRDAANLTL
HCCCCHHHEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHCCCEEE
SLSKMTLPHRLARVVLIEQLYRAFTILKGEPYHK
EHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA