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The map label for this gene is purN [H]

Identifier: 108763836

GI number: 108763836

Start: 3151150

End: 3151824

Strand: Reverse

Name: purN [H]

Synonym: MXAN_2700

Alternate gene names: 108763836

Gene position: 3151824-3151150 (Counterclockwise)

Preceding gene: 108763087

Following gene: 108760414

Centisome position: 34.48

GC content: 71.85

Gene sequence:

>675_bases
ATGAGCGGCCAGCGAGTCCGCCTGGGCGTGCTCGTGTCCGGCAGCGGGAGCAACCTCCAGGCGCTGCTGGACGCCTGTGC
GCGGGAGGACTTTCCCGCCGAGGTGGCCTGCGTGGTGTCCAACGTCTCCACCGCGTTCGCGCTGGAGCGGGCGCGCAAGG
CGGGCGTGACGGCCAAGGTGGTGGACCACAAGGCCCACGCGACGAAGGAGGGCTTCGAGAAGGCCCTGCTGGACACGCTG
CGCGCGGCGAACGTGGAGTGGGTGTGCCTTGCGGGGTTCATGCGCTTGTTGAGCGCGGACTTCCTGGGCCACTACGCGGG
GCGGGTGCTGAACATCCACCCGTCGCTGCTGCCCGCCTTCCCGGGCCTGCATGCGCAGCGACAGGCGCTGGAGCGAGGCG
TGAAAGTGGCCGGGTGCACGGTGCACTTCGTGGACGCGGGCACCGACACGGGGCCCATCATCGCGCAGGTGGCCGTGCCG
GTGCTGCCGGATGACGACGAGAAGGCCCTGAGTTCGCGAATCCTCGCGGAGGAGCACCGGCTCTACCCGCTGGCCGTGCG
GCTCGCCGTGACGGGCAAGGTGACGCTGGACGCGGCCCGCACGCGCGTGGAGGCGCGGGCCACGGTGGGCGAACTGGCGC
TTCGGAATCCCGGCGCGACGGTCGACCCGGCGTGA

Upstream 100 bases:

>100_bases
TCGCCCAGGCGCTGAGCGTGCTGAGCGGCCGGGGCGTGCAGGCCTTCGAGGTCGGCCGCGTGGAAGCGGGCCAGGGCGAG
GCCACGGCGGTCATCGACCC

Downstream 100 bases:

>100_bases
GCGGACCGAAGACGTTCGACCAGGAGCCGGAGTTCCCCAGCGCCACATCAGGGGATGACGGTGACGTTCAGCCACCGGAG
GCCGCTTTGGGGCTGACCAA

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MSGQRVRLGVLVSGSGSNLQALLDACAREDFPAEVACVVSNVSTAFALERARKAGVTAKVVDHKAHATKEGFEKALLDTL
RAANVEWVCLAGFMRLLSADFLGHYAGRVLNIHPSLLPAFPGLHAQRQALERGVKVAGCTVHFVDAGTDTGPIIAQVAVP
VLPDDDEKALSSRILAEEHRLYPLAVRLAVTGKVTLDAARTRVEARATVGELALRNPGATVDPA

Sequences:

>Translated_224_residues
MSGQRVRLGVLVSGSGSNLQALLDACAREDFPAEVACVVSNVSTAFALERARKAGVTAKVVDHKAHATKEGFEKALLDTL
RAANVEWVCLAGFMRLLSADFLGHYAGRVLNIHPSLLPAFPGLHAQRQALERGVKVAGCTVHFVDAGTDTGPIIAQVAVP
VLPDDDEKALSSRILAEEHRLYPLAVRLAVTGKVTLDAARTRVEARATVGELALRNPGATVDPA
>Mature_223_residues
SGQRVRLGVLVSGSGSNLQALLDACAREDFPAEVACVVSNVSTAFALERARKAGVTAKVVDHKAHATKEGFEKALLDTLR
AANVEWVCLAGFMRLLSADFLGHYAGRVLNIHPSLLPAFPGLHAQRQALERGVKVAGCTVHFVDAGTDTGPIIAQVAVPV
LPDDDEKALSSRILAEEHRLYPLAVRLAVTGKVTLDAARTRVEARATVGELALRNPGATVDPA

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=193, Percent_Identity=44.559585492228, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI209869995, Length=193, Percent_Identity=44.559585492228, Blast_Score=175, Evalue=3e-44,
Organism=Homo sapiens, GI209869993, Length=193, Percent_Identity=44.559585492228, Blast_Score=175, Evalue=3e-44,
Organism=Escherichia coli, GI1788846, Length=187, Percent_Identity=45.4545454545455, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1787483, Length=157, Percent_Identity=33.1210191082803, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17567511, Length=191, Percent_Identity=41.8848167539267, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320616, Length=198, Percent_Identity=30.3030303030303, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24582400, Length=194, Percent_Identity=52.0618556701031, Blast_Score=206, Evalue=1e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 23687; Mature: 23556

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQRVRLGVLVSGSGSNLQALLDACAREDFPAEVACVVSNVSTAFALERARKAGVTAKV
CCCCEEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VDHKAHATKEGFEKALLDTLRAANVEWVCLAGFMRLLSADFLGHYAGRVLNIHPSLLPAF
HHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHCC
PGLHAQRQALERGVKVAGCTVHFVDAGTDTGPIIAQVAVPVLPDDDEKALSSRILAEEHR
CCCHHHHHHHHCCCEEECEEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
LYPLAVRLAVTGKVTLDAARTRVEARATVGELALRNPGATVDPA
EEEEEEEEEEECEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SGQRVRLGVLVSGSGSNLQALLDACAREDFPAEVACVVSNVSTAFALERARKAGVTAKV
CCCEEEEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VDHKAHATKEGFEKALLDTLRAANVEWVCLAGFMRLLSADFLGHYAGRVLNIHPSLLPAF
HHCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECHHHHHCC
PGLHAQRQALERGVKVAGCTVHFVDAGTDTGPIIAQVAVPVLPDDDEKALSSRILAEEHR
CCCHHHHHHHHCCCEEECEEEEEEECCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCC
LYPLAVRLAVTGKVTLDAARTRVEARATVGELALRNPGATVDPA
EEEEEEEEEEECEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]