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The map label for this gene is pgl [H]

Identifier: 108763790

GI number: 108763790

Start: 1093919

End: 1094590

Strand: Reverse

Name: pgl [H]

Synonym: MXAN_0952

Alternate gene names: 108763790

Gene position: 1094590-1093919 (Counterclockwise)

Preceding gene: 108761123

Following gene: 108762961

Centisome position: 11.98

GC content: 73.36

Gene sequence:

>672_bases
ATGAGCGCCACGCGCACGCACGTCGTGCCCACCGAGTCCCTGCCCCGGGAAGCCGCGACGTGGATGGCGCGCGCGCTCCA
GGACACGCTCGCCACCCAGCGTCGCGTCAGCCTGGCCCTGTCGGGCGGCAGCACGCCGGGGCCCGCGTACCGGGCGCTGG
CGGCGCAGGTACTTCCCTGGGAGCGCGTGGACGTCTACTTCGTGGACGAGCGCTTCGTGCCGCCCGACCACGCGGACAGC
AACTACCGGATGGTGGAGGACACACTGCTGCGTCCTCTTCGGCTGTCGCCGTCGCAGGTGTTCCGCATGGAGGGTGAGCG
CGAGGACCGGGACGCCGCCGCGAAGGACTACGCGGCGAAGCTGCCTGCTTCCCTGGACGTGGTGCTGCTGGGCATGGGGG
AGGACGGGCACACGGCCAGCCTCTTCCCCGGCCACCCCGCGCTGGAGGAATCCGAGCAGCGCGTCCTGGCGGTGGTGGGG
CCCAAGCCGCCGCCCTGGCGGATGACGTTGACGCTGCCGGTATTGCGGTCCGCGCGGCACGTGCTGACCCTCGTATCGGG
GGCGGGCAAGCAGGACACGGTGCGCCGGGCGCTGGCGGGGGACCTGAGCCTCCCCGCCGCCCGGGTGACGAATTCGGAGT
GGATGCTGGACCCCGCCGCCGCCGGGCGGTGA

Upstream 100 bases:

>100_bases
CCGGCGAGGGCGGACCGGCGCACGGCTACCCCGGTGGCAGCGCGGGCCCGGATGCCGCGGCCGCGCTGCTGGCCCGCGAT
GGCCGCCGGTGGACCGGCCT

Downstream 100 bases:

>100_bases
GGGCTCCCAGTCGCGAACCTTCCAGGAGGAACCAACGATGAGTGAGTCAGCGGGCGCGCAGTTCGGCGTGGCGGGAATGG
GCGTCATGGGGGCGAGCCTC

Product: 6-phosphogluconolactonase

Products: NA

Alternate protein names: 6PGL [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSATRTHVVPTESLPREAATWMARALQDTLATQRRVSLALSGGSTPGPAYRALAAQVLPWERVDVYFVDERFVPPDHADS
NYRMVEDTLLRPLRLSPSQVFRMEGEREDRDAAAKDYAAKLPASLDVVLLGMGEDGHTASLFPGHPALEESEQRVLAVVG
PKPPPWRMTLTLPVLRSARHVLTLVSGAGKQDTVRRALAGDLSLPAARVTNSEWMLDPAAAGR

Sequences:

>Translated_223_residues
MSATRTHVVPTESLPREAATWMARALQDTLATQRRVSLALSGGSTPGPAYRALAAQVLPWERVDVYFVDERFVPPDHADS
NYRMVEDTLLRPLRLSPSQVFRMEGEREDRDAAAKDYAAKLPASLDVVLLGMGEDGHTASLFPGHPALEESEQRVLAVVG
PKPPPWRMTLTLPVLRSARHVLTLVSGAGKQDTVRRALAGDLSLPAARVTNSEWMLDPAAAGR
>Mature_222_residues
SATRTHVVPTESLPREAATWMARALQDTLATQRRVSLALSGGSTPGPAYRALAAQVLPWERVDVYFVDERFVPPDHADSN
YRMVEDTLLRPLRLSPSQVFRMEGEREDRDAAAKDYAAKLPASLDVVLLGMGEDGHTASLFPGHPALEESEQRVLAVVGP
KPPPWRMTLTLPVLRSARHVLTLVSGAGKQDTVRRALAGDLSLPAARVTNSEWMLDPAAAGR

Specific function: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily [H]

Homologues:

Organism=Homo sapiens, GI6912586, Length=207, Percent_Identity=42.0289855072464, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI52145310, Length=171, Percent_Identity=36.8421052631579, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI115533058, Length=208, Percent_Identity=34.1346153846154, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI115533060, Length=208, Percent_Identity=34.1346153846154, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17554876, Length=205, Percent_Identity=24.8780487804878, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321687, Length=212, Percent_Identity=36.3207547169811, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6321957, Length=233, Percent_Identity=32.618025751073, Blast_Score=107, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641119, Length=219, Percent_Identity=36.0730593607306, Blast_Score=115, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005900
- InterPro:   IPR006148 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.1.1.31 [H]

Molecular weight: Translated: 24323; Mature: 24192

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATRTHVVPTESLPREAATWMARALQDTLATQRRVSLALSGGSTPGPAYRALAAQVLPW
CCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCC
ERVDVYFVDERFVPPDHADSNYRMVEDTLLRPLRLSPSQVFRMEGEREDRDAAAKDYAAK
CCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHH
LPASLDVVLLGMGEDGHTASLFPGHPALEESEQRVLAVVGPKPPPWRMTLTLPVLRSARH
CCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHH
VLTLVSGAGKQDTVRRALAGDLSLPAARVTNSEWMLDPAAAGR
HHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCCCEEECCCCCCC
>Mature Secondary Structure 
SATRTHVVPTESLPREAATWMARALQDTLATQRRVSLALSGGSTPGPAYRALAAQVLPW
CCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHCCC
ERVDVYFVDERFVPPDHADSNYRMVEDTLLRPLRLSPSQVFRMEGEREDRDAAAKDYAAK
CCEEEEEECCCCCCCCCCCCCCEEHHHHHCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHH
LPASLDVVLLGMGEDGHTASLFPGHPALEESEQRVLAVVGPKPPPWRMTLTLPVLRSARH
CCCCEEEEEEEECCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHH
VLTLVSGAGKQDTVRRALAGDLSLPAARVTNSEWMLDPAAAGR
HHHHHCCCCCHHHHHHHHHCCCCCCHHHCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]