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The map label for this gene is zwf [H]

Identifier: 108761123

GI number: 108761123

Start: 1094587

End: 1096131

Strand: Reverse

Name: zwf [H]

Synonym: MXAN_0953

Alternate gene names: 108761123

Gene position: 1096131-1094587 (Counterclockwise)

Preceding gene: 108759438

Following gene: 108763790

Centisome position: 11.99

GC content: 68.09

Gene sequence:

>1545_bases
ATGGACGCGCATCAGGGCCTGCACATCGAGACCCATCCCCGAGAAGGAGACCCGCTGGTTCGCGCCCGGCGGCCCGACCC
GTGCGCGCTGGTGTTGTTCGGCGCCACCGGAGACCTGGCCCAGCGCAAGCTGTTCCCGGCCCTCTTCGAGTTGGCGCGAG
CCCACCTGCTGCCGAAGAACTTCGCCGTCGTCGCCTTCAGCCGCTCCGAAGGAGACAGCGAGGCCTTCCGCGAGCATGTG
AAGGCGTCCCTGCTGAAGTTCGCCCGCACCCAGCCCCTGGACGAGGCCGTCTGGAACGACTTCGCCCCGCGCCTGGAGCT
CATCTCCGGCGGCTATGACGACCCGAAGTCCTTCGTGCGCCTGCGCGAGGAGCTCGACCGGGTCGCCCAGAAGTTCGGCA
CCCAGGGCAACCAGTTCTATTACCTGGCCACTCCGGCCTCCACCTTCCCCCAAATCCTCCAGGGCCTGTCGGAGTCGGGG
CTGCTGAAGCGCCAGGAACAGGCCGACCCGCGCCCGTGGCAGCGGCTCATCATCGAGAAGCCCTTCGGCCACGATTTGGA
GAGCGCCCGCGCGCTCAACCGTGAGCTGGCGGCGGTGCTGGACGAGCGGCAGATATTCCGCATCGACCACTACCTGGGCA
AGGAGACGGTCCAGAACATCCTCGTCTTCCGCTTCGCCAATGCCATCTTCGAGCCGCTGTGGAACCGGCAGCACATCGAC
CACGTGGAAATCACCGCGGCGGAGACGCTGGGGGTGGAGGGGCGCGGCGGCTTCTACGACGAGACGGGCGTCATCCGGGA
CATGGTGCAGAACCACCTGCTCCAGGTGCTCGCGCTGTGTGCAATGGAACCGCCCGTGTCCTTCGGCGCCGAGGACATCC
GCGACGAAAAGACCAAGGTCTTCCGCGCGCTGCGCCCGCTGGAGGGCCGCGAGGTGTCCCGCGCGGTGGTGGCCGGCCAG
TACGAGGGTTACCTCCAGGAGAAGGGCGTGAAGGCCGGCTCGCGCACGCCGACCTATGTCGCCATGAAGATGAACATCGA
CAACTGGCGCTGGGCGGGCGTGCCCTTCTATCTGCGCGCGGGCAAGAAGCTGAAGCGGCGCGTGACGGAGGTGTCCATCC
ACTTCAAATCGGTGCCCATCAGCCTCTTCTCCGGGGAAGGCGCCACCTGCCAGCGGCTGCAGCCCAACGTGCTCACGCTG
CGCATCCAGCCCCAGGAAGGCATCGCGCTCTCCTTCGAATCCAAGGTGCCGGGCGAGGATGTCAACATCGCGGGCGTCAC
CATGGACTTCAACTATCAGGAGACCTTCCAGCGGCCGGTCCCCGAGGCCTACGAGCGCCTGCTGCTGGACTGCATGCGCG
GCAACGCCACCCTCTACGCGCGGCAGGACAGCGTGGAGCAGGCGTGGACCTTCGTGACGCCCATCCTCCAAGCCCTGGAG
TCCGGCGAGGGCGGACCGGCGCACGGCTACCCCGGTGGCAGCGCGGGCCCGGATGCCGCGGCCGCGCTGCTGGCCCGCGA
TGGCCGCCGGTGGACCGGCCTATGA

Upstream 100 bases:

>100_bases
GCAACGTCGGACCGGCGTCACTGCCCGCACTCTCCCTTGCCCGGTGGTTGCTCGGAAGGCGTAAGGTGCCTGCCGGACCG
AACCCGGAGGGAGGCAGCGA

Downstream 100 bases:

>100_bases
GCGCCACGCGCACGCACGTCGTGCCCACCGAGTCCCTGCCCCGGGAAGCCGCGACGTGGATGGCGCGCGCGCTCCAGGAC
ACGCTCGCCACCCAGCGTCG

Product: glucose-6-phosphate 1-dehydrogenase

Products: NA

Alternate protein names: G6PD [H]

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MDAHQGLHIETHPREGDPLVRARRPDPCALVLFGATGDLAQRKLFPALFELARAHLLPKNFAVVAFSRSEGDSEAFREHV
KASLLKFARTQPLDEAVWNDFAPRLELISGGYDDPKSFVRLREELDRVAQKFGTQGNQFYYLATPASTFPQILQGLSESG
LLKRQEQADPRPWQRLIIEKPFGHDLESARALNRELAAVLDERQIFRIDHYLGKETVQNILVFRFANAIFEPLWNRQHID
HVEITAAETLGVEGRGGFYDETGVIRDMVQNHLLQVLALCAMEPPVSFGAEDIRDEKTKVFRALRPLEGREVSRAVVAGQ
YEGYLQEKGVKAGSRTPTYVAMKMNIDNWRWAGVPFYLRAGKKLKRRVTEVSIHFKSVPISLFSGEGATCQRLQPNVLTL
RIQPQEGIALSFESKVPGEDVNIAGVTMDFNYQETFQRPVPEAYERLLLDCMRGNATLYARQDSVEQAWTFVTPILQALE
SGEGGPAHGYPGGSAGPDAAAALLARDGRRWTGL

Sequences:

>Translated_514_residues
MDAHQGLHIETHPREGDPLVRARRPDPCALVLFGATGDLAQRKLFPALFELARAHLLPKNFAVVAFSRSEGDSEAFREHV
KASLLKFARTQPLDEAVWNDFAPRLELISGGYDDPKSFVRLREELDRVAQKFGTQGNQFYYLATPASTFPQILQGLSESG
LLKRQEQADPRPWQRLIIEKPFGHDLESARALNRELAAVLDERQIFRIDHYLGKETVQNILVFRFANAIFEPLWNRQHID
HVEITAAETLGVEGRGGFYDETGVIRDMVQNHLLQVLALCAMEPPVSFGAEDIRDEKTKVFRALRPLEGREVSRAVVAGQ
YEGYLQEKGVKAGSRTPTYVAMKMNIDNWRWAGVPFYLRAGKKLKRRVTEVSIHFKSVPISLFSGEGATCQRLQPNVLTL
RIQPQEGIALSFESKVPGEDVNIAGVTMDFNYQETFQRPVPEAYERLLLDCMRGNATLYARQDSVEQAWTFVTPILQALE
SGEGGPAHGYPGGSAGPDAAAALLARDGRRWTGL
>Mature_514_residues
MDAHQGLHIETHPREGDPLVRARRPDPCALVLFGATGDLAQRKLFPALFELARAHLLPKNFAVVAFSRSEGDSEAFREHV
KASLLKFARTQPLDEAVWNDFAPRLELISGGYDDPKSFVRLREELDRVAQKFGTQGNQFYYLATPASTFPQILQGLSESG
LLKRQEQADPRPWQRLIIEKPFGHDLESARALNRELAAVLDERQIFRIDHYLGKETVQNILVFRFANAIFEPLWNRQHID
HVEITAAETLGVEGRGGFYDETGVIRDMVQNHLLQVLALCAMEPPVSFGAEDIRDEKTKVFRALRPLEGREVSRAVVAGQ
YEGYLQEKGVKAGSRTPTYVAMKMNIDNWRWAGVPFYLRAGKKLKRRVTEVSIHFKSVPISLFSGEGATCQRLQPNVLTL
RIQPQEGIALSFESKVPGEDVNIAGVTMDFNYQETFQRPVPEAYERLLLDCMRGNATLYARQDSVEQAWTFVTPILQALE
SGEGGPAHGYPGGSAGPDAAAALLARDGRRWTGL

Specific function: Pentose phosphate pathway; first step. [C]

COG id: COG0364

COG function: function code G; Glucose-6-phosphate 1-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-6-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI108773793, Length=500, Percent_Identity=37.8, Blast_Score=343, Evalue=3e-94,
Organism=Homo sapiens, GI109389365, Length=500, Percent_Identity=37.8, Blast_Score=343, Evalue=3e-94,
Organism=Homo sapiens, GI52145310, Length=507, Percent_Identity=31.163708086785, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1788158, Length=498, Percent_Identity=42.3694779116466, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17538218, Length=501, Percent_Identity=39.5209580838323, Blast_Score=362, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6324088, Length=487, Percent_Identity=35.7289527720739, Blast_Score=309, Evalue=5e-85,
Organism=Drosophila melanogaster, GI24643350, Length=500, Percent_Identity=37.6, Blast_Score=336, Evalue=2e-92,
Organism=Drosophila melanogaster, GI24643352, Length=500, Percent_Identity=37.6, Blast_Score=336, Evalue=3e-92,
Organism=Drosophila melanogaster, GI221513548, Length=494, Percent_Identity=30.5668016194332, Blast_Score=236, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001282
- InterPro:   IPR019796
- InterPro:   IPR022675
- InterPro:   IPR022674
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02781 G6PD_C; PF00479 G6PD_N [H]

EC number: =1.1.1.49 [H]

Molecular weight: Translated: 57592; Mature: 57592

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00069 G6P_DEHYDROGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAHQGLHIETHPREGDPLVRARRPDPCALVLFGATGDLAQRKLFPALFELARAHLLPKN
CCCCCCCEEEECCCCCCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
FAVVAFSRSEGDSEAFREHVKASLLKFARTQPLDEAVWNDFAPRLELISGGYDDPKSFVR
EEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LREELDRVAQKFGTQGNQFYYLATPASTFPQILQGLSESGLLKRQEQADPRPWQRLIIEK
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHCCC
PFGHDLESARALNRELAAVLDERQIFRIDHYLGKETVQNILVFRFANAIFEPLWNRQHID
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCC
HVEITAAETLGVEGRGGFYDETGVIRDMVQNHLLQVLALCAMEPPVSFGAEDIRDEKTKV
EEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
FRALRPLEGREVSRAVVAGQYEGYLQEKGVKAGSRTPTYVAMKMNIDNWRWAGVPFYLRA
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEECCCCHHHHC
GKKLKRRVTEVSIHFKSVPISLFSGEGATCQRLQPNVLTLRIQPQEGIALSFESKVPGED
CHHHHHHHHHHEEEEEECCEEEECCCCCCHHCCCCCEEEEEEECCCCEEEEECCCCCCCC
VNIAGVTMDFNYQETFQRPVPEAYERLLLDCMRGNATLYARQDSVEQAWTFVTPILQALE
CEEEEEEEECCHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
SGEGGPAHGYPGGSAGPDAAAALLARDGRRWTGL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDAHQGLHIETHPREGDPLVRARRPDPCALVLFGATGDLAQRKLFPALFELARAHLLPKN
CCCCCCCEEEECCCCCCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
FAVVAFSRSEGDSEAFREHVKASLLKFARTQPLDEAVWNDFAPRLELISGGYDDPKSFVR
EEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LREELDRVAQKFGTQGNQFYYLATPASTFPQILQGLSESGLLKRQEQADPRPWQRLIIEK
HHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHCCC
PFGHDLESARALNRELAAVLDERQIFRIDHYLGKETVQNILVFRFANAIFEPLWNRQHID
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCC
HVEITAAETLGVEGRGGFYDETGVIRDMVQNHLLQVLALCAMEPPVSFGAEDIRDEKTKV
EEEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
FRALRPLEGREVSRAVVAGQYEGYLQEKGVKAGSRTPTYVAMKMNIDNWRWAGVPFYLRA
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEEECCCCHHHHC
GKKLKRRVTEVSIHFKSVPISLFSGEGATCQRLQPNVLTLRIQPQEGIALSFESKVPGED
CHHHHHHHHHHEEEEEECCEEEECCCCCCHHCCCCCEEEEEEECCCCEEEEECCCCCCCC
VNIAGVTMDFNYQETFQRPVPEAYERLLLDCMRGNATLYARQDSVEQAWTFVTPILQALE
CEEEEEEEECCHHHHHCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHH
SGEGGPAHGYPGGSAGPDAAAALLARDGRRWTGL
CCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]