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The map label for this gene is frzCD [H]

Identifier: 108763763

GI number: 108763763

Start: 3185457

End: 3187028

Strand: Direct

Name: frzCD [H]

Synonym: MXAN_2735

Alternate gene names: 108763763

Gene position: 3185457-3187028 (Clockwise)

Preceding gene: 108762826

Following gene: 108761309

Centisome position: 34.85

GC content: 70.67

Gene sequence:

>1572_bases
ATGGCAAGCATGTGGGGCCGGCTCGGCTTGCGGACGCAGGTGGCCATCGCGGTGCTCGTGCCGTGCCTGGCGGTGGTGAG
CTTCTGCGTCGTGTACTTCCCCATGCACCAGCGGGAAGTCACGCTGGAGTTGCTCCAGAAGCGGGTGCGGGTGGTGGCGC
GGCTGATATCGCAGCACCCCGCGCTCCTGTCCGCGGACAGCACGCCGGAATCCACGGCCCGGGTGCGGGACGTGTTGTCG
ATGCTGGAGGCCCCGGAGGCGCTGAACGAGCGCGGTGGCTTCACCCTGCGCTACCAGGGGCTGGTGTCGGCGGAAGGCAC
CGTGCTCCATGGGCGCGGCTCCATTCCCACGGCCATCCGCTCGCTCGGCGTGGAGGGGCTGGAGGGCTGCGCCACGTCCA
CCCAACACGACGAGGTGTCGGTCCGCTGCGCCAGTGGTGAGCGCATCTACGTGGCGGGCTTCGGCGTCCAGGAGGCGCTC
AGCTCGGTGGATGACATGCGGGGCGCGGTGCTGGCCGGCCTGGCGGGCGCGCTGGTGCTGGGGCTGGCCCTGTCGTTGTT
CATCAGCCGCGCCATCGCCGAACCGGTGGCCCGGGTGACGGAGGTGGTGCGGGACGTGGCCCGGGGTGACATGTCGCGCG
GGGAACTGGACGTGCCGGCCACGGGCGAGGTGCGCCTCATGGCGCAGTCGTTCAACAAGATGCTGGGCACGCTGCGCACC
TCGGTGATGGAGATGGTTTCGCGCACGGAGCAGTTGTCCGGCGCATCGCGGGGCCTGTTGGGGGCGTCCGCGGACCAGGA
ACACGTCATCAGCCAGCAGGCGGCGTACGCGCAGCAGATTGCCGCCACGTTCGAGGAGCTGAGCCGCACGGCCGAGCAGA
TCTCCAGCTCCACGGAGGTGGTGGAGTCGAGCGCGCGGCGCACCCACGAGGCCGTGGCGGAGGCCATGGCGGTGGTTGCG
CAGGTGGTGGCGGGCATCAACGACATCCGCACCGAGTCCAAGGGCGTCGCGGACGCGATTGTCGGCCTCAACCAGGACCT
TCAGCAGGTGTCGAAGATTGCCCAGGTCATCAACCAGGTGGCGGAGCGCTCCGACTTGCTGGCGCTGAACGCGGCGCTGG
AGGGCACCAAGGCGGGCGAGGTGGGGCGGGGCTTCTCGCTGGTGGCCGCGGAGATGCGCAAGCTGGCGGAGAACGTGTCC
GCATCCGCGCGTGACATCGCCCGCATCGTGGAGAAGGTGCAGGACTCCGGCGAGGAAGCGGCAGCCAAGGCCCGCGTGGG
CATGGCCACCAGCGACCGGGGCGTGGAGGTGGCCGAGCAGGCCTCCTCCGTGTTCCAGCGAATCGTCGAGCTGGCGCGCG
GCACCAGCGAGGCGGCCCGGCAGATCACCATCGCCACCCGTCAGCAGCGCCAGTCCAGTGAGCAGGCCGTGCAGGGCGCC
CGCAACGTCGCGGAGCTGGTGAAGCAGGGCGTGGACGCGACGGGACGCACCACGCGCATCGCCCAGGACCTGCAGGCGGT
GGCCGAGGGGCTCACCGCCGTCACCAGCCGCTTCAAGACGACGCGGAACTGA

Upstream 100 bases:

>100_bases
CGGCTCCAGTCTGGCCGGCCGGTTTGACGCTCCGCGAAGGGACGCCTACCGTCCGAGAACCGTCGGCATCCATCCGGCGT
GAAACTTTCTCACCGGGGAG

Downstream 100 bases:

>100_bases
GGCTCACTCCCGCTGCCAGCGCAGCTGGAACTCGACCTCGTCCACGCCGTCCCCGCGCTCGTGCTCGATGTTGAAGAGCG
CGTCGGCGGGGATGCGCAGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MASMWGRLGLRTQVAIAVLVPCLAVVSFCVVYFPMHQREVTLELLQKRVRVVARLISQHPALLSADSTPESTARVRDVLS
MLEAPEALNERGGFTLRYQGLVSAEGTVLHGRGSIPTAIRSLGVEGLEGCATSTQHDEVSVRCASGERIYVAGFGVQEAL
SSVDDMRGAVLAGLAGALVLGLALSLFISRAIAEPVARVTEVVRDVARGDMSRGELDVPATGEVRLMAQSFNKMLGTLRT
SVMEMVSRTEQLSGASRGLLGASADQEHVISQQAAYAQQIAATFEELSRTAEQISSSTEVVESSARRTHEAVAEAMAVVA
QVVAGINDIRTESKGVADAIVGLNQDLQQVSKIAQVINQVAERSDLLALNAALEGTKAGEVGRGFSLVAAEMRKLAENVS
ASARDIARIVEKVQDSGEEAAAKARVGMATSDRGVEVAEQASSVFQRIVELARGTSEAARQITIATRQQRQSSEQAVQGA
RNVAELVKQGVDATGRTTRIAQDLQAVAEGLTAVTSRFKTTRN

Sequences:

>Translated_523_residues
MASMWGRLGLRTQVAIAVLVPCLAVVSFCVVYFPMHQREVTLELLQKRVRVVARLISQHPALLSADSTPESTARVRDVLS
MLEAPEALNERGGFTLRYQGLVSAEGTVLHGRGSIPTAIRSLGVEGLEGCATSTQHDEVSVRCASGERIYVAGFGVQEAL
SSVDDMRGAVLAGLAGALVLGLALSLFISRAIAEPVARVTEVVRDVARGDMSRGELDVPATGEVRLMAQSFNKMLGTLRT
SVMEMVSRTEQLSGASRGLLGASADQEHVISQQAAYAQQIAATFEELSRTAEQISSSTEVVESSARRTHEAVAEAMAVVA
QVVAGINDIRTESKGVADAIVGLNQDLQQVSKIAQVINQVAERSDLLALNAALEGTKAGEVGRGFSLVAAEMRKLAENVS
ASARDIARIVEKVQDSGEEAAAKARVGMATSDRGVEVAEQASSVFQRIVELARGTSEAARQITIATRQQRQSSEQAVQGA
RNVAELVKQGVDATGRTTRIAQDLQAVAEGLTAVTSRFKTTRN
>Mature_522_residues
ASMWGRLGLRTQVAIAVLVPCLAVVSFCVVYFPMHQREVTLELLQKRVRVVARLISQHPALLSADSTPESTARVRDVLSM
LEAPEALNERGGFTLRYQGLVSAEGTVLHGRGSIPTAIRSLGVEGLEGCATSTQHDEVSVRCASGERIYVAGFGVQEALS
SVDDMRGAVLAGLAGALVLGLALSLFISRAIAEPVARVTEVVRDVARGDMSRGELDVPATGEVRLMAQSFNKMLGTLRTS
VMEMVSRTEQLSGASRGLLGASADQEHVISQQAAYAQQIAATFEELSRTAEQISSSTEVVESSARRTHEAVAEAMAVVAQ
VVAGINDIRTESKGVADAIVGLNQDLQQVSKIAQVINQVAERSDLLALNAALEGTKAGEVGRGFSLVAAEMRKLAENVSA
SARDIARIVEKVQDSGEEAAAKARVGMATSDRGVEVAEQASSVFQRIVELARGTSEAARQITIATRQQRQSSEQAVQGAR
NVAELVKQGVDATGRTTRIAQDLQAVAEGLTAVTSRFKTTRN

Specific function: Methyl-accepting taxis protein necessary for the proper aggregation of cells to form fruiting bodies. Frz genes define a system of signal transduction analogous to the enterobacterial chemotaxis systems [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=235, Percent_Identity=31.063829787234, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787690, Length=305, Percent_Identity=27.5409836065574, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788195, Length=224, Percent_Identity=28.125, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789453, Length=311, Percent_Identity=25.4019292604502, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788194, Length=244, Percent_Identity=26.6393442622951, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089 [H]

Pfam domain/function: PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 55473; Mature: 55342

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASMWGRLGLRTQVAIAVLVPCLAVVSFCVVYFPMHQREVTLELLQKRVRVVARLISQHP
CCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
ALLSADSTPESTARVRDVLSMLEAPEALNERGGFTLRYQGLVSAEGTVLHGRGSIPTAIR
CEEECCCCCHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCEECCCCEEEECCCCCHHHHH
SLGVEGLEGCATSTQHDEVSVRCASGERIYVAGFGVQEALSSVDDMRGAVLAGLAGALVL
HCCCHHHHHCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLALSLFISRAIAEPVARVTEVVRDVARGDMSRGELDVPATGEVRLMAQSFNKMLGTLRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SVMEMVSRTEQLSGASRGLLGASADQEHVISQQAAYAQQIAATFEELSRTAEQISSSTEV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VESSARRTHEAVAEAMAVVAQVVAGINDIRTESKGVADAIVGLNQDLQQVSKIAQVINQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHH
AERSDLLALNAALEGTKAGEVGRGFSLVAAEMRKLAENVSASARDIARIVEKVQDSGEEA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHH
AAKARVGMATSDRGVEVAEQASSVFQRIVELARGTSEAARQITIATRQQRQSSEQAVQGA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNVAELVKQGVDATGRTTRIAQDLQAVAEGLTAVTSRFKTTRN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASMWGRLGLRTQVAIAVLVPCLAVVSFCVVYFPMHQREVTLELLQKRVRVVARLISQHP
CCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
ALLSADSTPESTARVRDVLSMLEAPEALNERGGFTLRYQGLVSAEGTVLHGRGSIPTAIR
CEEECCCCCHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCEECCCCEEEECCCCCHHHHH
SLGVEGLEGCATSTQHDEVSVRCASGERIYVAGFGVQEALSSVDDMRGAVLAGLAGALVL
HCCCHHHHHCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLALSLFISRAIAEPVARVTEVVRDVARGDMSRGELDVPATGEVRLMAQSFNKMLGTLRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
SVMEMVSRTEQLSGASRGLLGASADQEHVISQQAAYAQQIAATFEELSRTAEQISSSTEV
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VESSARRTHEAVAEAMAVVAQVVAGINDIRTESKGVADAIVGLNQDLQQVSKIAQVINQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHHHHHHH
AERSDLLALNAALEGTKAGEVGRGFSLVAAEMRKLAENVSASARDIARIVEKVQDSGEEA
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHH
AAKARVGMATSDRGVEVAEQASSVFQRIVELARGTSEAARQITIATRQQRQSSEQAVQGA
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RNVAELVKQGVDATGRTTRIAQDLQAVAEGLTAVTSRFKTTRN
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2492105; 1624419 [H]