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The map label for this gene is fabH [H]

Identifier: 108763242

GI number: 108763242

Start: 262363

End: 263358

Strand: Direct

Name: fabH [H]

Synonym: MXAN_0215

Alternate gene names: 108763242

Gene position: 262363-263358 (Clockwise)

Preceding gene: 108759272

Following gene: 108762666

Centisome position: 2.87

GC content: 67.17

Gene sequence:

>996_bases
ATGCGATACGCCCAGATTCTCTCCACTGGCCGCTACGTCCCCGAGAAGGTCCTCACCAACGCTGACGTCGAGAAGATTCT
CGGTGAGAAGGTGGATGAGTGGCTCCAGCAGAACGTGGGCATTCGCGAACGCCACATGATGGCGGATGACCAGGCCACCT
CCGACCTCTGCGTGGGCGCCGCCCGCCAGGCGCTGGAGCGCGCGGGCACGAAGCCGGAGGAACTGGACCTCATCATCATC
GCCACCGATACCCCGGACTATCTCAGCCCCGCCACGGCCTCCGTGGTGCAGGCGAAGCTGGGCGCGGTGAACGCCGGCAC
CTACGACCTCAACTGCGCGTGCGCGGGCTGGGTGACGGCGCTGGACGTGGGCTCGAAGACGATTGCCGCGGATGACAGCT
ACCAGCGCATCCTCGTCGTGGGCGCCTACGGCATGTCGCGCTACATCAACTGGAAGGACAAGAAGACCGCCACCCTGTTC
GCGGACGGCGCGGGCGCGGTCGTGCTGGGCGCGGGTGACACGCCCGGCTTCATGGGCGCGAAGCTGCTGGCCAACGGCGA
GTACCACGACGCGCTGGGTGTCTACACCGGCGGTACGAACCGCCCGGCCACCGCGGAGTCGCTGGAGCTCACGGGCGGCA
AGCCCGCGGTGCAGTTCGTCCGCAAGTTCCCGGCGACGTTCAACACCGAGCGCTGGCCCATGCTGCTGGACCAGCTCCTC
AAGCGGCAGAACCTGAAGCTGGACGACGTGAAGCAGTTCGTCTTCACGCAGCTCAACCTGCGCACCATCGAAGCCACCAT
GAAGATCCTGGGCCAGCCGATGGAGAAGGCCCACTACACCATGGACAAGTGGGGCTACACCGGTTCGGCCTGCATCCCGA
TGACGCTGGATGACGCGGTGGTGCAGGGCAAGGTGCAGCGCGGCGACCTGGTGGCCCTGTGTGCCAGCGGCGGCGGGCTC
GCCATGGCCTCCGCCCTCTACCGCTGGACGGCCTGA

Upstream 100 bases:

>100_bases
GCCGAAGCCGAAGCTGAAGCCCAAACCGAAGCCCCTGAAGAAGAACACCCTGCGTCCCGCCCGCCGACCGGCGCGCGGCG
CCCGGAGCTGACGAACACTC

Downstream 100 bases:

>100_bases
GTCACGCCATGACGGAGGGCGCGCACATGTTCATCGGTGACTGGATGGGCCGTGGCGCCCTCTACTGGCCCGACAGTGTC
GCGGTGGTGGACCCGTCCCG

Product: putative 3-oxoacyl-(acyl-carrier-protein) synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MRYAQILSTGRYVPEKVLTNADVEKILGEKVDEWLQQNVGIRERHMMADDQATSDLCVGAARQALERAGTKPEELDLIII
ATDTPDYLSPATASVVQAKLGAVNAGTYDLNCACAGWVTALDVGSKTIAADDSYQRILVVGAYGMSRYINWKDKKTATLF
ADGAGAVVLGAGDTPGFMGAKLLANGEYHDALGVYTGGTNRPATAESLELTGGKPAVQFVRKFPATFNTERWPMLLDQLL
KRQNLKLDDVKQFVFTQLNLRTIEATMKILGQPMEKAHYTMDKWGYTGSACIPMTLDDAVVQGKVQRGDLVALCASGGGL
AMASALYRWTA

Sequences:

>Translated_331_residues
MRYAQILSTGRYVPEKVLTNADVEKILGEKVDEWLQQNVGIRERHMMADDQATSDLCVGAARQALERAGTKPEELDLIII
ATDTPDYLSPATASVVQAKLGAVNAGTYDLNCACAGWVTALDVGSKTIAADDSYQRILVVGAYGMSRYINWKDKKTATLF
ADGAGAVVLGAGDTPGFMGAKLLANGEYHDALGVYTGGTNRPATAESLELTGGKPAVQFVRKFPATFNTERWPMLLDQLL
KRQNLKLDDVKQFVFTQLNLRTIEATMKILGQPMEKAHYTMDKWGYTGSACIPMTLDDAVVQGKVQRGDLVALCASGGGL
AMASALYRWTA
>Mature_331_residues
MRYAQILSTGRYVPEKVLTNADVEKILGEKVDEWLQQNVGIRERHMMADDQATSDLCVGAARQALERAGTKPEELDLIII
ATDTPDYLSPATASVVQAKLGAVNAGTYDLNCACAGWVTALDVGSKTIAADDSYQRILVVGAYGMSRYINWKDKKTATLF
ADGAGAVVLGAGDTPGFMGAKLLANGEYHDALGVYTGGTNRPATAESLELTGGKPAVQFVRKFPATFNTERWPMLLDQLL
KRQNLKLDDVKQFVFTQLNLRTIEATMKILGQPMEKAHYTMDKWGYTGSACIPMTLDDAVVQGKVQRGDLVALCASGGGL
AMASALYRWTA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=327, Percent_Identity=35.474006116208, Blast_Score=192, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35783; Mature: 35783

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYAQILSTGRYVPEKVLTNADVEKILGEKVDEWLQQNVGIRERHMMADDQATSDLCVGA
CCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHH
ARQALERAGTKPEELDLIIIATDTPDYLSPATASVVQAKLGAVNAGTYDLNCACAGWVTA
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEECEEHHHHHHH
LDVGSKTIAADDSYQRILVVGAYGMSRYINWKDKKTATLFADGAGAVVLGAGDTPGFMGA
HHCCCCEEECCCCCCEEEEEEECCHHHEECCCCCCEEEEEECCCCEEEEECCCCCCCCCH
KLLANGEYHDALGVYTGGTNRPATAESLELTGGKPAVQFVRKFPATFNTERWPMLLDQLL
HEEECCCCCCCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
KRQNLKLDDVKQFVFTQLNLRTIEATMKILGQPMEKAHYTMDKWGYTGSACIPMTLDDAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCEEEEECCHHH
VQGKVQRGDLVALCASGGGLAMASALYRWTA
HHCCCCCCCEEEEEECCCCHHHHHHHHHCCC
>Mature Secondary Structure
MRYAQILSTGRYVPEKVLTNADVEKILGEKVDEWLQQNVGIRERHMMADDQATSDLCVGA
CCHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHH
ARQALERAGTKPEELDLIIIATDTPDYLSPATASVVQAKLGAVNAGTYDLNCACAGWVTA
HHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEEECEEHHHHHHH
LDVGSKTIAADDSYQRILVVGAYGMSRYINWKDKKTATLFADGAGAVVLGAGDTPGFMGA
HHCCCCEEECCCCCCEEEEEEECCHHHEECCCCCCEEEEEECCCCEEEEECCCCCCCCCH
KLLANGEYHDALGVYTGGTNRPATAESLELTGGKPAVQFVRKFPATFNTERWPMLLDQLL
HEEECCCCCCCEEEEECCCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHH
KRQNLKLDDVKQFVFTQLNLRTIEATMKILGQPMEKAHYTMDKWGYTGSACIPMTLDDAV
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHCCCCCCCEEEEECCHHH
VQGKVQRGDLVALCASGGGLAMASALYRWTA
HHCCCCCCCEEEEEECCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]