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The map label for this gene is tdk [H]

Identifier: 108763197

GI number: 108763197

Start: 6347838

End: 6348437

Strand: Reverse

Name: tdk [H]

Synonym: MXAN_5072

Alternate gene names: 108763197

Gene position: 6348437-6347838 (Counterclockwise)

Preceding gene: 108760113

Following gene: 108762470

Centisome position: 69.46

GC content: 64.67

Gene sequence:

>600_bases
TTGCACCAATTCCCCAAAGATATCGGGTGGATAGAGGTCATCTGCGGTTCGATGTTCTCCGGCAAGACGGAGGAGCTGAT
CCGCCGCGTCCAACGCGCCGTCTACGGCAAGCAGAAGGTGCAGGTCTTCAAGCCGCGCATCGACAACCGCTACGACGAAT
CCGCGGTGGTGAGCCACTCGCAGCACAAGGTGCTGTCCACCGCCATCGAGCGGGCTGAAGAGATTTTTTACAGGCTCGCG
CCCGACACCCAGGTGGTGGGCATCGACGAGGTGCAGTTCTTCGGTTCAGAAGTGGTCGCCGTGGTGGAGGCGCTGGCCAA
CAAGGGCCTGCGCGTCATCTGCGCGGGCCTGGACCAGGACTACCAGGGGCGCCCCTTCGAACCGATGCCCCAGTTGATGG
CGGTGTCGGAGTACGTGACGAAGGAGCTGGCCATCTGCGTGGTGTGCGGGAATCCGGCCAACCGCTCCCAGCGCATCGTG
TCCAGTGGTGAGCGGGTGGTGGTGGGCGCGGCGGGCGCGTACGAACCGCGCTGCCGCAAGTGTCACGTGGCGGAACCGGC
GGAGGGCACGCCGCCGCAGACGTTGGAACTGTTCGACTGA

Upstream 100 bases:

>100_bases
GGGACGATTCGGCTATGGGACGGGCGTGGCGGGAAGTTGACTCCCCTGGGGTCGTGGCAGACTATCCGCGCCCTTTCCGC
CCCCGGCCCGTGAGCGTTCC

Downstream 100 bases:

>100_bases
GCGGGAGCTGAACGGATGCGCGACACCCTGTACTCCAACGTTCCCTTCAAGCTGAACGAGATGCCCCACCACTATGGGCC
TCACGTCCACCTGGTGGGAA

Product: thymidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MHQFPKDIGWIEVICGSMFSGKTEELIRRVQRAVYGKQKVQVFKPRIDNRYDESAVVSHSQHKVLSTAIERAEEIFYRLA
PDTQVVGIDEVQFFGSEVVAVVEALANKGLRVICAGLDQDYQGRPFEPMPQLMAVSEYVTKELAICVVCGNPANRSQRIV
SSGERVVVGAAGAYEPRCRKCHVAEPAEGTPPQTLELFD

Sequences:

>Translated_199_residues
MHQFPKDIGWIEVICGSMFSGKTEELIRRVQRAVYGKQKVQVFKPRIDNRYDESAVVSHSQHKVLSTAIERAEEIFYRLA
PDTQVVGIDEVQFFGSEVVAVVEALANKGLRVICAGLDQDYQGRPFEPMPQLMAVSEYVTKELAICVVCGNPANRSQRIV
SSGERVVVGAAGAYEPRCRKCHVAEPAEGTPPQTLELFD
>Mature_199_residues
MHQFPKDIGWIEVICGSMFSGKTEELIRRVQRAVYGKQKVQVFKPRIDNRYDESAVVSHSQHKVLSTAIERAEEIFYRLA
PDTQVVGIDEVQFFGSEVVAVVEALANKGLRVICAGLDQDYQGRPFEPMPQLMAVSEYVTKELAICVVCGNPANRSQRIV
SSGERVVVGAAGAYEPRCRKCHVAEPAEGTPPQTLELFD

Specific function: Phosphorylates Both Thymidine And Deoxyuridine. [C]

COG id: COG1435

COG function: function code F; Thymidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine kinase family [H]

Homologues:

Organism=Homo sapiens, GI164698438, Length=190, Percent_Identity=37.8947368421053, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17543396, Length=187, Percent_Identity=34.2245989304813, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001267
- InterPro:   IPR020633
- InterPro:   IPR020634 [H]

Pfam domain/function: PF00265 TK [H]

EC number: =2.7.1.21 [H]

Molecular weight: Translated: 22127; Mature: 22127

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQFPKDIGWIEVICGSMFSGKTEELIRRVQRAVYGKQKVQVFKPRIDNRYDESAVVSHS
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCHHHHHHH
QHKVLSTAIERAEEIFYRLAPDTQVVGIDEVQFFGSEVVAVVEALANKGLRVICAGLDQD
HHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
YQGRPFEPMPQLMAVSEYVTKELAICVVCGNPANRSQRIVSSGERVVVGAAGAYEPRCRK
CCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHCCCEEEEECCCCCCCCCCC
CHVAEPAEGTPPQTLELFD
CCCCCCCCCCCCCCEECCC
>Mature Secondary Structure
MHQFPKDIGWIEVICGSMFSGKTEELIRRVQRAVYGKQKVQVFKPRIDNRYDESAVVSHS
CCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHEEECCCCCCCCCCHHHHHHH
QHKVLSTAIERAEEIFYRLAPDTQVVGIDEVQFFGSEVVAVVEALANKGLRVICAGLDQD
HHHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCC
YQGRPFEPMPQLMAVSEYVTKELAICVVCGNPANRSQRIVSSGERVVVGAAGAYEPRCRK
CCCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHHCCCEEEEECCCCCCCCCCC
CHVAEPAEGTPPQTLELFD
CCCCCCCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]