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The map label for this gene is tipA [H]

Identifier: 108763023

GI number: 108763023

Start: 6395543

End: 6396328

Strand: Reverse

Name: tipA [H]

Synonym: MXAN_5120

Alternate gene names: 108763023

Gene position: 6396328-6395543 (Counterclockwise)

Preceding gene: 108763387

Following gene: 108758244

Centisome position: 69.98

GC content: 68.07

Gene sequence:

>786_bases
GTGGAGATGGCCCTGACGGTGAGCCAGGTCGCCCGGCTGGCGAAAATCAGCATCCGCGCGTTGCACCACTATGACGAGCT
GGGCCTGTTGTGTCCTTCGGACCGCAGCGAGGCCGGCTACCGGCTCTATTCACAGGCGGACCTCCAGAAGCTCCAACAGG
TGCTCTTCTTCAAGGAGCTGGGCTTCCCGCTGGAGGACATCCGCCGCATCCTGGGCGACCCCACCTTCGACCTGCGCACC
GCGCTGCGGATGCAGCGGCAGCTCCTGACGGAGCGGGCCGCCCGTCTGGACGCGCTGGTGCATGCCGTGGACGCGGCGCT
GGACGCGCTGGAGAAGGGGACGCACGTGGACAAGGAAGCGATGTTCGAGGCCTTTGGCGACTTCGACCCCTCGAAGTACG
AGGAGGAGGCGAAGCAGCGCTGGGGGAACACGGAGGCCTACAAGGAATCCGCCCGGAGGACGGCGCGCTACAAGAAGGAG
GACTGGAAGCGCATCAAGGAGGAGGGGGACGTCCTCTTCCAGGCGTTGGCGGACCTGCTCGCGGCGGGCACCAGCGCCGC
GTCGGCCGCGGCCATGGACCTGGCCGAGGCGCACCGGCAATACCTGGGCAGGTGGTTCTACGCGTGCCCACCCGCCATGC
ACCGGGGCCTGGGGGAGATGTACGTGGCGGATACGCGCTTCACGGAGAACATCGACAAGGCGCGCCCTGGCCTGTCGCTG
TTCCTACGGGATGCCTTCGCGGCCAACGCGGAGCGACAGGGGGCCGCCGATGTTCCCTGCGGCTAG

Upstream 100 bases:

>100_bases
GGCTGAGTCGTCAGCCCGGTGCCCGGCCGGAAGTGGCAGCACCCCCGCCCAGGGGCTTGACCCTCACGCGACGTGAGGCC
CTACACCTCCTCATCAAGAG

Downstream 100 bases:

>100_bases
CTGAAGCCCAGCCGCTTCAGCATCACCGCGCGGATGGAGGGAATCCGGAAGCGGTAGATGAGCGCGTCCGCGAAGTAGTG
CGCCAGCACCACCGCGAAGC

Product: transcriptional activator TipA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MEMALTVSQVARLAKISIRALHHYDELGLLCPSDRSEAGYRLYSQADLQKLQQVLFFKELGFPLEDIRRILGDPTFDLRT
ALRMQRQLLTERAARLDALVHAVDAALDALEKGTHVDKEAMFEAFGDFDPSKYEEEAKQRWGNTEAYKESARRTARYKKE
DWKRIKEEGDVLFQALADLLAAGTSAASAAAMDLAEAHRQYLGRWFYACPPAMHRGLGEMYVADTRFTENIDKARPGLSL
FLRDAFAANAERQGAADVPCG

Sequences:

>Translated_261_residues
MEMALTVSQVARLAKISIRALHHYDELGLLCPSDRSEAGYRLYSQADLQKLQQVLFFKELGFPLEDIRRILGDPTFDLRT
ALRMQRQLLTERAARLDALVHAVDAALDALEKGTHVDKEAMFEAFGDFDPSKYEEEAKQRWGNTEAYKESARRTARYKKE
DWKRIKEEGDVLFQALADLLAAGTSAASAAAMDLAEAHRQYLGRWFYACPPAMHRGLGEMYVADTRFTENIDKARPGLSL
FLRDAFAANAERQGAADVPCG
>Mature_261_residues
MEMALTVSQVARLAKISIRALHHYDELGLLCPSDRSEAGYRLYSQADLQKLQQVLFFKELGFPLEDIRRILGDPTFDLRT
ALRMQRQLLTERAARLDALVHAVDAALDALEKGTHVDKEAMFEAFGDFDPSKYEEEAKQRWGNTEAYKESARRTARYKKE
DWKRIKEEGDVLFQALADLLAAGTSAASAAAMDLAEAHRQYLGRWFYACPPAMHRGLGEMYVADTRFTENIDKARPGLSL
FLRDAFAANAERQGAADVPCG

Specific function: Transcriptional activator. Is activated when bound to the antibiotic thiostrepton [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR012925
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind; PF07739 TipAS [H]

EC number: NA

Molecular weight: Translated: 29394; Mature: 29394

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEMALTVSQVARLAKISIRALHHYDELGLLCPSDRSEAGYRLYSQADLQKLQQVLFFKEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFPLEDIRRILGDPTFDLRTALRMQRQLLTERAARLDALVHAVDAALDALEKGTHVDKEA
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
MFEAFGDFDPSKYEEEAKQRWGNTEAYKESARRTARYKKEDWKRIKEEGDVLFQALADLL
HHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGTSAASAAAMDLAEAHRQYLGRWFYACPPAMHRGLGEMYVADTRFTENIDKARPGLSL
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHH
FLRDAFAANAERQGAADVPCG
HHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEMALTVSQVARLAKISIRALHHYDELGLLCPSDRSEAGYRLYSQADLQKLQQVLFFKEL
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
GFPLEDIRRILGDPTFDLRTALRMQRQLLTERAARLDALVHAVDAALDALEKGTHVDKEA
CCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
MFEAFGDFDPSKYEEEAKQRWGNTEAYKESARRTARYKKEDWKRIKEEGDVLFQALADLL
HHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGTSAASAAAMDLAEAHRQYLGRWFYACPPAMHRGLGEMYVADTRFTENIDKARPGLSL
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHH
FLRDAFAANAERQGAADVPCG
HHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]