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The map label for this gene is mtaD [H]

Identifier: 108758244

GI number: 108758244

Start: 6392974

End: 6394299

Strand: Reverse

Name: mtaD [H]

Synonym: MXAN_5118

Alternate gene names: 108758244

Gene position: 6394299-6392974 (Counterclockwise)

Preceding gene: 108763023

Following gene: 108764079

Centisome position: 69.96

GC content: 72.32

Gene sequence:

>1326_bases
ATGGAAGGCCGCCTGCTTCTGAAAAACTGTGCCGTGTTCAGGGCGGACGGACGCGTCCGCCATGGCATGGCCGTGGTGGT
GGAAGGCAACACCATCCGCCGCATGGCTCCGGACGCCCAGGTGCCCGTGCTGCCCGGGGACTGGGAAGTCGCCTGTCATG
GCCGGCTGGTGGCGCCAGGCCTGGTGGACTGTCACACGCACCTCGTCAACGGCCAGTTGCTGCCGCCGACGGGACACTTC
CTGATGCTCCCGCCCCGCGAGCGCCTGGACCGGCTCCGGCACGTGGCGCGGCTGCTCACGAACGAGGACGTGGAGGCCCT
CACCCGCTACGCGGCGGCCCGGGCCCTGCGTCACGGCGTCACCCTGGCGGTGGAGCACCTGTCCTGCCAGGACGTGGCCG
GAGGACTCGCCGCCCAGGCTCGCGCCGCGGAGGCGGTGGGCTTGCGGTTGGTGACGAGCCACTCCACCCACGGATTGGAC
GGCGCCGCGCAGGCGCAGGCGTGGCTGGACGCCAACGCGGACTTCACGCGCGCGCATCGGGACCACCCGCTGGTCCGGGG
GGCGCTTGGCTTCCATGCGTCGTTCACCTGTGACGACGCGCTGCTGCGCCGCATCGCGGAGCTGAGCCGGGTGCTGGACG
CGCCCACCGTCTTCCATCTCGCGGAGAGCGAGGACGACCTCTCCTCCACCTACTCGCAGCACGGCAAACGCGTGGTTCCG
CGGCTGGATGCGCTGGGGCTGCTCGGGCCGCGTGCCATCGCGGGCTATGCGCGCGTGCTGGACAGCGCGGAGGCGGAGCT
GCTGGAGCAGAGCGGTGCCTTCGTGGCGCTGGCGGCCCGGGGCGTGCGCGCGCTGGAGCGTGGCGCGGACCCCATGGACG
CGGTGCTGTCGCGGGTCCACCTGCTGGGGCTCGGCACCGGGGGCCATGGCAGCCTCCAGGACGAACTGCTCGCCGCGCTG
GTGGGCGTGCTGCGCATCTCCCGTTCCGGAAGGCTGCCGGACGTGGATGGCGCGCTGGCGCACCTGCTCGTCAACGGCCC
GGCGGAGCTGTGCACGCGGCTGTTCGGCCTGCCCTCCGGGAGCGTGGAGGAGGGGAGCATCGCGGACCTCGTCGTCTACG
ACGTCGTGCCCACCGCGGATCCGGAGACGGGCTACTCGCCCTATCTGCTCGGGCAACTGGCGCATTCGCCGGTGGGATGG
ACCATCGTGAACGGCCGGGTCTGCGTGCGGGAGGGGCAGTTGCTGGGGCTCGACTACGTGGCGCTTTCCCGTGCGGCGAC
CGAGGCGCTGGAGCGTGTCTGGACGCGCGCGCGTCTGGGCAGTTGA

Upstream 100 bases:

>100_bases
ACGGCGGGGCTCAGCGGCGTCATACCGTACGGACCCTAACATGCCCGCTGGCGGCGGCGCCGCTCGCGTCGCGCCGTGCC
CGTGTTAGAACAGGGCTTTC

Downstream 100 bases:

>100_bases
GCGGCGGCATGGGCACACTGGCTTCTTCTCTCGTGGAGACGCTGCGCGCCTCGCGCGGCCGGCGCGGGCCGCTGCTGGGA
GACGCGCGGACCACGGCCTG

Product: amidohydrolase domain-containing protein

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MEGRLLLKNCAVFRADGRVRHGMAVVVEGNTIRRMAPDAQVPVLPGDWEVACHGRLVAPGLVDCHTHLVNGQLLPPTGHF
LMLPPRERLDRLRHVARLLTNEDVEALTRYAAARALRHGVTLAVEHLSCQDVAGGLAAQARAAEAVGLRLVTSHSTHGLD
GAAQAQAWLDANADFTRAHRDHPLVRGALGFHASFTCDDALLRRIAELSRVLDAPTVFHLAESEDDLSSTYSQHGKRVVP
RLDALGLLGPRAIAGYARVLDSAEAELLEQSGAFVALAARGVRALERGADPMDAVLSRVHLLGLGTGGHGSLQDELLAAL
VGVLRISRSGRLPDVDGALAHLLVNGPAELCTRLFGLPSGSVEEGSIADLVVYDVVPTADPETGYSPYLLGQLAHSPVGW
TIVNGRVCVREGQLLGLDYVALSRAATEALERVWTRARLGS

Sequences:

>Translated_441_residues
MEGRLLLKNCAVFRADGRVRHGMAVVVEGNTIRRMAPDAQVPVLPGDWEVACHGRLVAPGLVDCHTHLVNGQLLPPTGHF
LMLPPRERLDRLRHVARLLTNEDVEALTRYAAARALRHGVTLAVEHLSCQDVAGGLAAQARAAEAVGLRLVTSHSTHGLD
GAAQAQAWLDANADFTRAHRDHPLVRGALGFHASFTCDDALLRRIAELSRVLDAPTVFHLAESEDDLSSTYSQHGKRVVP
RLDALGLLGPRAIAGYARVLDSAEAELLEQSGAFVALAARGVRALERGADPMDAVLSRVHLLGLGTGGHGSLQDELLAAL
VGVLRISRSGRLPDVDGALAHLLVNGPAELCTRLFGLPSGSVEEGSIADLVVYDVVPTADPETGYSPYLLGQLAHSPVGW
TIVNGRVCVREGQLLGLDYVALSRAATEALERVWTRARLGS
>Mature_441_residues
MEGRLLLKNCAVFRADGRVRHGMAVVVEGNTIRRMAPDAQVPVLPGDWEVACHGRLVAPGLVDCHTHLVNGQLLPPTGHF
LMLPPRERLDRLRHVARLLTNEDVEALTRYAAARALRHGVTLAVEHLSCQDVAGGLAAQARAAEAVGLRLVTSHSTHGLD
GAAQAQAWLDANADFTRAHRDHPLVRGALGFHASFTCDDALLRRIAELSRVLDAPTVFHLAESEDDLSSTYSQHGKRVVP
RLDALGLLGPRAIAGYARVLDSAEAELLEQSGAFVALAARGVRALERGADPMDAVLSRVHLLGLGTGGHGSLQDELLAAL
VGVLRISRSGRLPDVDGALAHLLVNGPAELCTRLFGLPSGSVEEGSIADLVVYDVVPTADPETGYSPYLLGQLAHSPVGW
TIVNGRVCVREGQLLGLDYVALSRAATEALERVWTRARLGS

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Escherichia coli, GI87082177, Length=454, Percent_Identity=28.1938325991189, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 47032; Mature: 47032

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGRLLLKNCAVFRADGRVRHGMAVVVEGNTIRRMAPDAQVPVLPGDWEVACHGRLVAPG
CCCCEEEECCEEEECCCCEECCEEEEEECCEEEECCCCCCCCCCCCCCEEEECCEEECCC
LVDCHTHLVNGQLLPPTGHFLMLPPRERLDRLRHVARLLTNEDVEALTRYAAARALRHGV
HHHHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
TLAVEHLSCQDVAGGLAAQARAAEAVGLRLVTSHSTHGLDGAAQAQAWLDANADFTRAHR
EEEEECCCHHHHHCCHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHC
DHPLVRGALGFHASFTCDDALLRRIAELSRVLDAPTVFHLAESEDDLSSTYSQHGKRVVP
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCEECC
RLDALGLLGPRAIAGYARVLDSAEAELLEQSGAFVALAARGVRALERGADPMDAVLSRVH
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHHHHH
LLGLGTGGHGSLQDELLAALVGVLRISRSGRLPDVDGALAHLLVNGPAELCTRLFGLPSG
HEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
SVEEGSIADLVVYDVVPTADPETGYSPYLLGQLAHSPVGWTIVNGRVCVREGQLLGLDYV
CCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEECCEEEEECCCEECCHHH
ALSRAATEALERVWTRARLGS
HHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEGRLLLKNCAVFRADGRVRHGMAVVVEGNTIRRMAPDAQVPVLPGDWEVACHGRLVAPG
CCCCEEEECCEEEECCCCEECCEEEEEECCEEEECCCCCCCCCCCCCCEEEECCEEECCC
LVDCHTHLVNGQLLPPTGHFLMLPPRERLDRLRHVARLLTNEDVEALTRYAAARALRHGV
HHHHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCC
TLAVEHLSCQDVAGGLAAQARAAEAVGLRLVTSHSTHGLDGAAQAQAWLDANADFTRAHR
EEEEECCCHHHHHCCHHHHHHHHHHHCEEEEECCCCCCCCCHHHHHHHHCCCCCHHHHHC
DHPLVRGALGFHASFTCDDALLRRIAELSRVLDAPTVFHLAESEDDLSSTYSQHGKRVVP
CCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCEECC
RLDALGLLGPRAIAGYARVLDSAEAELLEQSGAFVALAARGVRALERGADPMDAVLSRVH
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHCCCHHHHHHHHHH
LLGLGTGGHGSLQDELLAALVGVLRISRSGRLPDVDGALAHLLVNGPAELCTRLFGLPSG
HEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCC
SVEEGSIADLVVYDVVPTADPETGYSPYLLGQLAHSPVGWTIVNGRVCVREGQLLGLDYV
CCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEECCEEEEECCCEECCHHH
ALSRAATEALERVWTRARLGS
HHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014 [H]