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The map label for this gene is yycG [H]

Identifier: 108762962

GI number: 108762962

Start: 213061

End: 214989

Strand: Direct

Name: yycG [H]

Synonym: MXAN_0176

Alternate gene names: 108762962

Gene position: 213061-214989 (Clockwise)

Preceding gene: 108762134

Following gene: 108760864

Centisome position: 2.33

GC content: 69.78

Gene sequence:

>1929_bases
GTGCTGGAGGTATTCGTGTTCGCCGCCGACACCTCCACCCACGTGGATGGGGTCGTTCTTGCTGTAGCCATAGCCGGAGG
GCGCGCTGGGCGCGCTGGGCGCGCTGGGCGTGGCCTCGGGGGCCGCCGCTTCCGTCGCGGGCTCGTCTGGCCGGGTGGCG
CCAGCGGTGGAGGCACAGCCCGTGGCCAGCACGGGCACCAGGAACAGCATCGCGAGGCGAGAGGTCGTCATGTGGCGGAA
GCCTACCGCTTTCGCATGGCAAGCGGCCTGGGAGTCGGAGCCCCTTCGGCGGTGGCGGCCGAGCAGGGGGGCCCCTTTCA
TGCCCTTGGCGGGCGCCGCATCTTTCCGCCGGAAATGTCCCGCCAACGAGGCCGAGGAGCGCCCATGTCGAAGGCCCACA
TCTATGAGGAAGGACGGAGCGGATGGGGCGCGCCTGGGGCTGCCGAGGCCCGTCACCCGAGCGGGCCCGACTTCGCTCCG
GCGCTGCTGAGATTGGGGCAGGCGCTCCAGGCGGCGCTCATCGTCGACGCGCACGGACGCGTGCTCTGGATGGACGATGC
GCTGACTCACGCCACCGGGCCGCAGGGAGAGCCCTTTCAAGGGCGTTCCGTGGCCGAGGTGCTCGCTCGGCTGCCCTGGC
TCGCGCAGGCGATGCAGCCCGCGCTCCAGGGCAAGGCCGGTGTTCACGAGGAGCCGGGCCTGACGGCCTTCGTCCTGCCC
ATGTTCGATGAGCAGGGGACATTGTTGGGAGCCTGCGCGCGCCTCCAGCTTCCTGAGTCCTCGATGGGGCAGGTCGCCGA
AGGCGGTCTGACGCGGCACGCGCCGGAGAGCCTGGCGCACATGAACTCGGTGCTGCGCGCCACGTTCGACTCGATTGCGG
AAGGCGTCATCGTGGTGGACCTGAACAAGCGCGTCACGGCCTTCAACAAGCGCTTCCTCGACATCTGGGGGCTGACCGAG
GAGATGATGGTGGACCGCGACGCGGAGCGGGTGCTGGTGCGCGCGGCGGGCGGCGTGAAACACCCGGAGTCGTTCACGTC
GCGAATCCGGGAGCGCTTCGAGCCGTCCGAAGAGGTGGACGTGGAGACGGTGGAGTTGCTGGACGGGCGCATCCTGGAGC
GCAAGTCGCTGCCGCAGCGGATGGGGGGCGCCATCATCGGCCGCGTGTGGAGCTACCGCGAGGTGACGGCGGAGCGGCAG
GCCGAGGCCGAGCGCGAGCGGCTGCTGCGCGAAGCCCAGGAGGCCATCCGCGTGCGGGACGACTTCCTGTCCATCGCCGC
GCACGAGCTGAAGACGCCGCTCACGCCGCTGAAGCTGCACCTCCAGATGCTGCGGCAACACGGCGCCGAGGGGGACGGGG
CCTCCGCCCGGCACGTGGACAAGTCGTTGATGCAGGTGAGCCGCCTGACGGGATTGGTGAATGACCTGCTGGACACCTCG
CGCATCCAGGAAGGGCGGCTGACGCTGAAGCATGGGCCCGTCGTGTTGCAGGAGCTGGCCCATGACGTCGTCTCCGAGAT
GCGCCTGTCCAGCGCGCACCACCGGGTCGAGTACGAAGCGCCGGAGGCACCCCTGGTCGTCCTGGGCGACGCGGACCGGC
TCGCGCAGGTCCTGGTCAACCTGATGGAGAACGCCTTCAAGTACAGCCCCAGTGGGGGAACGGTTCGCGTCCGGGTGGCT
CGGGAGGACCGCCACGCCCATGTCTCCGTCCAGGACGAAGGCATCGGCATTCCGCGGGATCAGCAGGAGCACCTCTTCGA
GCGCTTCTTCCGTGCTCGCAACGCCCCCATCTCCGGCTTTGGTGGGCTGGGGCTGGGGCTCTACATCTGCGGGGACATCG
TCGAGCGGCATGGCGGCCGTCTGTGGGTGGAGAGCGTGCTGGGGCACGGCTCCACCTTCCGCTTCACCGTGCCGCTGGCG
TCCACGTGA

Upstream 100 bases:

>100_bases
CGTCGAGCATGCCGCTGCCGAACGGCGCGCCCTCCGACTCGAAGGCGCAGCAGCTTCCTCCCCGCTCGTAGCGGATCTTC
TGCCCCTCTGGCCCCCGCAG

Downstream 100 bases:

>100_bases
CGGTGCCTCACCGGGGCAGGGCCTGCGCGGCCTGACGCTGGCGGGCCACGCGCAGGCGCCACACCGTCACGGGAATGCCC
ACGGCAAGAGGCGCCACGCT

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MLEVFVFAADTSTHVDGVVLAVAIAGGRAGRAGRAGRGLGGRRFRRGLVWPGGASGGGTARGQHGHQEQHREARGRHVAE
AYRFRMASGLGVGAPSAVAAEQGGPFHALGGRRIFPPEMSRQRGRGAPMSKAHIYEEGRSGWGAPGAAEARHPSGPDFAP
ALLRLGQALQAALIVDAHGRVLWMDDALTHATGPQGEPFQGRSVAEVLARLPWLAQAMQPALQGKAGVHEEPGLTAFVLP
MFDEQGTLLGACARLQLPESSMGQVAEGGLTRHAPESLAHMNSVLRATFDSIAEGVIVVDLNKRVTAFNKRFLDIWGLTE
EMMVDRDAERVLVRAAGGVKHPESFTSRIRERFEPSEEVDVETVELLDGRILERKSLPQRMGGAIIGRVWSYREVTAERQ
AEAERERLLREAQEAIRVRDDFLSIAAHELKTPLTPLKLHLQMLRQHGAEGDGASARHVDKSLMQVSRLTGLVNDLLDTS
RIQEGRLTLKHGPVVLQELAHDVVSEMRLSSAHHRVEYEAPEAPLVVLGDADRLAQVLVNLMENAFKYSPSGGTVRVRVA
REDRHAHVSVQDEGIGIPRDQQEHLFERFFRARNAPISGFGGLGLGLYICGDIVERHGGRLWVESVLGHGSTFRFTVPLA
ST

Sequences:

>Translated_642_residues
MLEVFVFAADTSTHVDGVVLAVAIAGGRAGRAGRAGRGLGGRRFRRGLVWPGGASGGGTARGQHGHQEQHREARGRHVAE
AYRFRMASGLGVGAPSAVAAEQGGPFHALGGRRIFPPEMSRQRGRGAPMSKAHIYEEGRSGWGAPGAAEARHPSGPDFAP
ALLRLGQALQAALIVDAHGRVLWMDDALTHATGPQGEPFQGRSVAEVLARLPWLAQAMQPALQGKAGVHEEPGLTAFVLP
MFDEQGTLLGACARLQLPESSMGQVAEGGLTRHAPESLAHMNSVLRATFDSIAEGVIVVDLNKRVTAFNKRFLDIWGLTE
EMMVDRDAERVLVRAAGGVKHPESFTSRIRERFEPSEEVDVETVELLDGRILERKSLPQRMGGAIIGRVWSYREVTAERQ
AEAERERLLREAQEAIRVRDDFLSIAAHELKTPLTPLKLHLQMLRQHGAEGDGASARHVDKSLMQVSRLTGLVNDLLDTS
RIQEGRLTLKHGPVVLQELAHDVVSEMRLSSAHHRVEYEAPEAPLVVLGDADRLAQVLVNLMENAFKYSPSGGTVRVRVA
REDRHAHVSVQDEGIGIPRDQQEHLFERFFRARNAPISGFGGLGLGLYICGDIVERHGGRLWVESVLGHGSTFRFTVPLA
ST
>Mature_642_residues
MLEVFVFAADTSTHVDGVVLAVAIAGGRAGRAGRAGRGLGGRRFRRGLVWPGGASGGGTARGQHGHQEQHREARGRHVAE
AYRFRMASGLGVGAPSAVAAEQGGPFHALGGRRIFPPEMSRQRGRGAPMSKAHIYEEGRSGWGAPGAAEARHPSGPDFAP
ALLRLGQALQAALIVDAHGRVLWMDDALTHATGPQGEPFQGRSVAEVLARLPWLAQAMQPALQGKAGVHEEPGLTAFVLP
MFDEQGTLLGACARLQLPESSMGQVAEGGLTRHAPESLAHMNSVLRATFDSIAEGVIVVDLNKRVTAFNKRFLDIWGLTE
EMMVDRDAERVLVRAAGGVKHPESFTSRIRERFEPSEEVDVETVELLDGRILERKSLPQRMGGAIIGRVWSYREVTAERQ
AEAERERLLREAQEAIRVRDDFLSIAAHELKTPLTPLKLHLQMLRQHGAEGDGASARHVDKSLMQVSRLTGLVNDLLDTS
RIQEGRLTLKHGPVVLQELAHDVVSEMRLSSAHHRVEYEAPEAPLVVLGDADRLAQVLVNLMENAFKYSPSGGTVRVRVA
REDRHAHVSVQDEGIGIPRDQQEHLFERFFRARNAPISGFGGLGLGLYICGDIVERHGGRLWVESVLGHGSTFRFTVPLA
ST

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=208, Percent_Identity=35.5769230769231, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1786912, Length=292, Percent_Identity=30.4794520547945, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=33.9366515837104, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1789149, Length=242, Percent_Identity=33.0578512396694, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI145693157, Length=249, Percent_Identity=27.710843373494, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI48994928, Length=243, Percent_Identity=28.8065843621399, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=396, Percent_Identity=24.2424242424242, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788713, Length=261, Percent_Identity=26.8199233716475, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=206, Percent_Identity=28.1553398058252, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790551, Length=211, Percent_Identity=32.2274881516588, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=28.2511210762332, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI87081816, Length=276, Percent_Identity=27.536231884058, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=222, Percent_Identity=28.3783783783784, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790861, Length=227, Percent_Identity=26.431718061674, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=25.8620689655172, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=28, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=29.4930875576037, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790300, Length=298, Percent_Identity=27.8523489932886, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1788279, Length=216, Percent_Identity=26.8518518518519, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69804; Mature: 69804

Theoretical pI: Translated: 7.75; Mature: 7.75

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEVFVFAADTSTHVDGVVLAVAIAGGRAGRAGRAGRGLGGRRFRRGLVWPGGASGGGTA
CEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
RGQHGHQEQHREARGRHVAEAYRFRMASGLGVGAPSAVAAEQGGPFHALGGRRIFPPEMS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEECCCCCCCCCHHH
RQRGRGAPMSKAHIYEEGRSGWGAPGAAEARHPSGPDFAPALLRLGQALQAALIVDAHGR
HHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCC
VLWMDDALTHATGPQGEPFQGRSVAEVLARLPWLAQAMQPALQGKAGVHEEPGLTAFVLP
EEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
MFDEQGTLLGACARLQLPESSMGQVAEGGLTRHAPESLAHMNSVLRATFDSIAEGVIVVD
EECCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
LNKRVTAFNKRFLDIWGLTEEMMVDRDAERVLVRAAGGVKHPESFTSRIRERFEPSEEVD
CCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCC
VETVELLDGRILERKSLPQRMGGAIIGRVWSYREVTAERQAEAERERLLREAQEAIRVRD
HHHHHHHCCHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFLSIAAHELKTPLTPLKLHLQMLRQHGAEGDGASARHVDKSLMQVSRLTGLVNDLLDTS
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RIQEGRLTLKHGPVVLQELAHDVVSEMRLSSAHHRVEYEAPEAPLVVLGDADRLAQVLVN
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCHHHHHHHHHH
LMENAFKYSPSGGTVRVRVAREDRHAHVSVQDEGIGIPRDQQEHLFERFFRARNAPISGF
HHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCC
GGLGLGLYICGDIVERHGGRLWVESVLGHGSTFRFTVPLAST
CCHHHHHHHHHHHHHHCCCEEEHHHHHCCCCEEEEEECCCCC
>Mature Secondary Structure
MLEVFVFAADTSTHVDGVVLAVAIAGGRAGRAGRAGRGLGGRRFRRGLVWPGGASGGGTA
CEEEEEEEECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCC
RGQHGHQEQHREARGRHVAEAYRFRMASGLGVGAPSAVAAEQGGPFHALGGRRIFPPEMS
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCEEECCCCCCCCCHHH
RQRGRGAPMSKAHIYEEGRSGWGAPGAAEARHPSGPDFAPALLRLGQALQAALIVDAHGR
HHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCC
VLWMDDALTHATGPQGEPFQGRSVAEVLARLPWLAQAMQPALQGKAGVHEEPGLTAFVLP
EEEECCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
MFDEQGTLLGACARLQLPESSMGQVAEGGLTRHAPESLAHMNSVLRATFDSIAEGVIVVD
EECCCCCHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEE
LNKRVTAFNKRFLDIWGLTEEMMVDRDAERVLVRAAGGVKHPESFTSRIRERFEPSEEVD
CCCHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCC
VETVELLDGRILERKSLPQRMGGAIIGRVWSYREVTAERQAEAERERLLREAQEAIRVRD
HHHHHHHCCHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DFLSIAAHELKTPLTPLKLHLQMLRQHGAEGDGASARHVDKSLMQVSRLTGLVNDLLDTS
HHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RIQEGRLTLKHGPVVLQELAHDVVSEMRLSSAHHRVEYEAPEAPLVVLGDADRLAQVLVN
HHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCEEEECCHHHHHHHHHH
LMENAFKYSPSGGTVRVRVAREDRHAHVSVQDEGIGIPRDQQEHLFERFFRARNAPISGF
HHHHHHEECCCCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCC
GGLGLGLYICGDIVERHGGRLWVESVLGHGSTFRFTVPLAST
CCHHHHHHHHHHHHHHCCCEEEHHHHHCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]