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The map label for this gene is aer [C]

Identifier: 108762134

GI number: 108762134

Start: 209306

End: 210898

Strand: Direct

Name: aer [C]

Synonym: MXAN_0174

Alternate gene names: 108762134

Gene position: 209306-210898 (Clockwise)

Preceding gene: 108762873

Following gene: 108762962

Centisome position: 2.29

GC content: 68.55

Gene sequence:

>1593_bases
GTGCGTCTGAAGCTCAAGCAGAAGATGATGTTGTTGCCGGCTGTTGTCGCGGTGTTCCTGGTGGCCATCCTGGTGGCGTT
CATCGCCCTGGGCGCGCGCTCCGGTGGCGTGTACGCGCGCATCAGCAGTTCGCAGGTTCCCACCATCGAGCTGAACCGTG
AGGTGATGCACCGCTTCCCGGGCCTGCACCGCAACGTGCTGGCGGCGGTGGCGGCGAAGGCGGGAGGGTTGGAGCCGCTG
AGCGCGGAGGTGGACGAGCTCCAGTCGAAGCTCGACCTGGCGGGGGCCGTACCGGACGCGAACCGCCAGCGGGTGGATGA
ACTCAAGTCGTCCCTGGCCACGTACTGGACGAACTCCAGGGCGGCGGTGACGTTCGCGGTGGAGGGGGACGAGAAGGCGG
CGTCCGCGCTCGCGAGCGTGGAGTCCCTGGCCGCCGCGCTGTCCCATGAGCTGGAGAGGGCCGTGGAAGCGGATGGCCAG
GCCATCGCGACCTCCTACGCGGAGGTGGCCGGGCTGCACCGCGCCACCACCTGGACGGTGTGCGTGCTGGTGCTGTTGTG
CATCGCGCTGACGGTGGGGCTGGCCTACTGGCTGCACCGCGAGGTGACGCTGCCGCTGGCGAAGCTGACCCACGTGGCCA
CGCGCATCGCGGAGAAGGGCGACCTGACGCAGGCCATCGACGTGAGCGCCCACGACGAGGTGGGCGAGCTGGCGCGCGGC
TTCCAGGTCATGGTGACCCGGCTGCGCAACGTGCCCACCACCATCCAGACGGTGGTGACGGACCTGACGAACGCGGCGAA
GACGCTGACGCAGGCCAGCCAGGAGCAGGTGAACTTCCTCACCAATCAGTCCCGCAGCCTCACCGAGGCGAGCACCACCA
TCGCCGAAATCGCGCAGACGTCCAGCATGGCCGCCAGCCGCGCGGAGATGGTGCTCCGCGTGGCGGGACAGGCGGATGCG
TTCAGCGCGTCCGGCCAGGAGTCCATCGAGAAGAGCGCCGAGGGCCTCCAGCAGATTCGCCAGCGCGTGGGCGCGCTGGT
GGGCAGCATCGCGCACCTGAGCGACCAGGCCGTGCATGCCGGTGAAATCATCGGCAGCGTGAAGGACCTGGCGGACCAGT
CCAACGTGCTCGCGCTCAACGCGGCCATCGAAGCGGCGCGCGCCGGGGAACAGGGCCGGGGCTTCGCGGTGGTGGCGCGG
GAGATGCGCTCGCTCAGCGGCCAGTCGCTGCAGAGCACCCAGCGCATCGGCAAGATTCTGCTCGAAATCAACCAGGCCAT
CCGCCAGACGGTGGGCATCGCCGAGGGCGACAGCGAGAAGATGGAGGAGGGCATCGAGCAGGTGCTCGCCTCGGCCAACA
CGCTGAAGGAAATCACCACCGTGGTGCAGGAGAGCAGTCAGGCCGCGCGCCAGATTGTGGCCTCCGTCACCCAGCAGAAC
GCGGGCATCGCGCAGATGACCGAGGTGATGACCACGCTGTCCTCCATGATGGCGGACGTGGTGACGGCCACGATGACGGC
CGAGCAGGCGGTGACGCAAATCAACGCGTCGCTGGGACAGCTCCATGAGCTGTCCACCGGCTTCCGCGTCTGA

Upstream 100 bases:

>100_bases
GGAAAACGGGGTGGCTCTTCCACAGCCGGATTCTGGCCGCGGCGCGCGGCGTGGAGTCGCAGGCGTTGAAGGGGGCTCAC
GGTAGCGGGGAGGCCAGCGG

Downstream 100 bases:

>100_bases
CGCCGCCTCGGGGCCGCGCGGGTGCCACCGTCCTGGGTGGCACCCCGGCTTGGGGCTCGGCTCACTCCCCCTGCATCAGC
CCGGTGACGCGCCCGTCGTC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MRLKLKQKMMLLPAVVAVFLVAILVAFIALGARSGGVYARISSSQVPTIELNREVMHRFPGLHRNVLAAVAAKAGGLEPL
SAEVDELQSKLDLAGAVPDANRQRVDELKSSLATYWTNSRAAVTFAVEGDEKAASALASVESLAAALSHELERAVEADGQ
AIATSYAEVAGLHRATTWTVCVLVLLCIALTVGLAYWLHREVTLPLAKLTHVATRIAEKGDLTQAIDVSAHDEVGELARG
FQVMVTRLRNVPTTIQTVVTDLTNAAKTLTQASQEQVNFLTNQSRSLTEASTTIAEIAQTSSMAASRAEMVLRVAGQADA
FSASGQESIEKSAEGLQQIRQRVGALVGSIAHLSDQAVHAGEIIGSVKDLADQSNVLALNAAIEAARAGEQGRGFAVVAR
EMRSLSGQSLQSTQRIGKILLEINQAIRQTVGIAEGDSEKMEEGIEQVLASANTLKEITTVVQESSQAARQIVASVTQQN
AGIAQMTEVMTTLSSMMADVVTATMTAEQAVTQINASLGQLHELSTGFRV

Sequences:

>Translated_530_residues
MRLKLKQKMMLLPAVVAVFLVAILVAFIALGARSGGVYARISSSQVPTIELNREVMHRFPGLHRNVLAAVAAKAGGLEPL
SAEVDELQSKLDLAGAVPDANRQRVDELKSSLATYWTNSRAAVTFAVEGDEKAASALASVESLAAALSHELERAVEADGQ
AIATSYAEVAGLHRATTWTVCVLVLLCIALTVGLAYWLHREVTLPLAKLTHVATRIAEKGDLTQAIDVSAHDEVGELARG
FQVMVTRLRNVPTTIQTVVTDLTNAAKTLTQASQEQVNFLTNQSRSLTEASTTIAEIAQTSSMAASRAEMVLRVAGQADA
FSASGQESIEKSAEGLQQIRQRVGALVGSIAHLSDQAVHAGEIIGSVKDLADQSNVLALNAAIEAARAGEQGRGFAVVAR
EMRSLSGQSLQSTQRIGKILLEINQAIRQTVGIAEGDSEKMEEGIEQVLASANTLKEITTVVQESSQAARQIVASVTQQN
AGIAQMTEVMTTLSSMMADVVTATMTAEQAVTQINASLGQLHELSTGFRV
>Mature_530_residues
MRLKLKQKMMLLPAVVAVFLVAILVAFIALGARSGGVYARISSSQVPTIELNREVMHRFPGLHRNVLAAVAAKAGGLEPL
SAEVDELQSKLDLAGAVPDANRQRVDELKSSLATYWTNSRAAVTFAVEGDEKAASALASVESLAAALSHELERAVEADGQ
AIATSYAEVAGLHRATTWTVCVLVLLCIALTVGLAYWLHREVTLPLAKLTHVATRIAEKGDLTQAIDVSAHDEVGELARG
FQVMVTRLRNVPTTIQTVVTDLTNAAKTLTQASQEQVNFLTNQSRSLTEASTTIAEIAQTSSMAASRAEMVLRVAGQADA
FSASGQESIEKSAEGLQQIRQRVGALVGSIAHLSDQAVHAGEIIGSVKDLADQSNVLALNAAIEAARAGEQGRGFAVVAR
EMRSLSGQSLQSTQRIGKILLEINQAIRQTVGIAEGDSEKMEEGIEQVLASANTLKEITTVVQESSQAARQIVASVTQQN
AGIAQMTEVMTTLSSMMADVVTATMTAEQAVTQINASLGQLHELSTGFRV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=318, Percent_Identity=27.3584905660377, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI2367378, Length=316, Percent_Identity=26.2658227848101, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1787690, Length=348, Percent_Identity=27.5862068965517, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1788195, Length=326, Percent_Identity=26.9938650306748, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788194, Length=326, Percent_Identity=24.5398773006135, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 56136; Mature: 56136

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKLKQKMMLLPAVVAVFLVAILVAFIALGARSGGVYARISSSQVPTIELNREVMHRFP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCHHHHHHCC
GLHRNVLAAVAAKAGGLEPLSAEVDELQSKLDLAGAVPDANRQRVDELKSSLATYWTNSR
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
AAVTFAVEGDEKAASALASVESLAAALSHELERAVEADGQAIATSYAEVAGLHRATTWTV
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
CVLVLLCIALTVGLAYWLHREVTLPLAKLTHVATRIAEKGDLTQAIDVSAHDEVGELARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHH
FQVMVTRLRNVPTTIQTVVTDLTNAAKTLTQASQEQVNFLTNQSRSLTEASTTIAEIAQT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SSMAASRAEMVLRVAGQADAFSASGQESIEKSAEGLQQIRQRVGALVGSIAHLSDQAVHA
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEIIGSVKDLADQSNVLALNAAIEAARAGEQGRGFAVVAREMRSLSGQSLQSTQRIGKIL
HHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LEINQAIRQTVGIAEGDSEKMEEGIEQVLASANTLKEITTVVQESSQAARQIVASVTQQN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGIAQMTEVMTTLSSMMADVVTATMTAEQAVTQINASLGQLHELSTGFRV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRLKLKQKMMLLPAVVAVFLVAILVAFIALGARSGGVYARISSSQVPTIELNREVMHRFP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCHHHHHHCC
GLHRNVLAAVAAKAGGLEPLSAEVDELQSKLDLAGAVPDANRQRVDELKSSLATYWTNSR
CHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCC
AAVTFAVEGDEKAASALASVESLAAALSHELERAVEADGQAIATSYAEVAGLHRATTWTV
EEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
CVLVLLCIALTVGLAYWLHREVTLPLAKLTHVATRIAEKGDLTQAIDVSAHDEVGELARG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHH
FQVMVTRLRNVPTTIQTVVTDLTNAAKTLTQASQEQVNFLTNQSRSLTEASTTIAEIAQT
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
SSMAASRAEMVLRVAGQADAFSASGQESIEKSAEGLQQIRQRVGALVGSIAHLSDQAVHA
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GEIIGSVKDLADQSNVLALNAAIEAARAGEQGRGFAVVAREMRSLSGQSLQSTQRIGKIL
HHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHH
LEINQAIRQTVGIAEGDSEKMEEGIEQVLASANTLKEITTVVQESSQAARQIVASVTQQN
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AGIAQMTEVMTTLSSMMADVVTATMTAEQAVTQINASLGQLHELSTGFRV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA