Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 108762828

GI number: 108762828

Start: 435385

End: 435993

Strand: Direct

Name: lspA [H]

Synonym: MXAN_0369

Alternate gene names: 108762828

Gene position: 435385-435993 (Clockwise)

Preceding gene: 108757607

Following gene: 108762523

Centisome position: 4.76

GC content: 65.68

Gene sequence:

>609_bases
GTGCCGCGCAAATACATCATCCTCCTCGCCGTCACCCTTGGCGTCATCGTGCTCGACCAGTGGACGAAGTACCTCGTCGT
CCGCGAGCTGACCACCCAGATGGAAGGCAAGGAGAGCCTGGGCGAGCGCCTGGCCTCGATGTACTCCGAGCCGCCCCCCA
AGGGCTTCACGGGGATGCACTATCAGCCCCGGCGGCACATCGAGATTTCGGAGTCGTTCTTCCGCATCCGCTACCTGGAG
AACCCGGGCGCCGCGTGGGGCATGTTCCGGAGCATGCCGCCTGAGGCGCGGGTACCGCTCTTCCACGTGGCCATCATTGG
CGCGCTCATCCTCATCACTTTCAGCTTCCGCAAGCTGACCGGCACGGACCCGGAAGAGAAGTGGGCGCTGTGGGGGCTGC
CGTTGGTGCTGGGCGGCGCGCTGGGCAACTACATCGACCGCGTCGCCCGGGCCTTCGTCATCGACTTCCTCGAGGTCCAC
TGGTTCGACAAGGCGACCTTCCCGTCCTTCAACGTCGCCGACGCGGCCATCTGCATTGGCGTGGGCATGCTCATCATCGA
CTCCTTCGTCCGCAAGGAGAAGCCGGCCCAGGCCCCCACCCAGGCCTAG

Upstream 100 bases:

>100_bases
CATCAGCGTCGGGGTGGGTCTCATGCTGCTGGACTCGCTGCGGGCGCCGAAAAGCCCCAATCCGTGACGGGCGGGCGGCG
GCTGGTGTAAGTCCCGGCCC

Downstream 100 bases:

>100_bases
GCCGCCGCATCGGGCCGAGCAGCCAGGCGGCCCGGATGCGCGCATGCGTGTCGTCCCGCCCGCGCAACGAGGGTAGCCTT
CGTTGCCATGCTCCCCGTCC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MPRKYIILLAVTLGVIVLDQWTKYLVVRELTTQMEGKESLGERLASMYSEPPPKGFTGMHYQPRRHIEISESFFRIRYLE
NPGAAWGMFRSMPPEARVPLFHVAIIGALILITFSFRKLTGTDPEEKWALWGLPLVLGGALGNYIDRVARAFVIDFLEVH
WFDKATFPSFNVADAAICIGVGMLIIDSFVRKEKPAQAPTQA

Sequences:

>Translated_202_residues
MPRKYIILLAVTLGVIVLDQWTKYLVVRELTTQMEGKESLGERLASMYSEPPPKGFTGMHYQPRRHIEISESFFRIRYLE
NPGAAWGMFRSMPPEARVPLFHVAIIGALILITFSFRKLTGTDPEEKWALWGLPLVLGGALGNYIDRVARAFVIDFLEVH
WFDKATFPSFNVADAAICIGVGMLIIDSFVRKEKPAQAPTQA
>Mature_201_residues
PRKYIILLAVTLGVIVLDQWTKYLVVRELTTQMEGKESLGERLASMYSEPPPKGFTGMHYQPRRHIEISESFFRIRYLEN
PGAAWGMFRSMPPEARVPLFHVAIIGALILITFSFRKLTGTDPEEKWALWGLPLVLGGALGNYIDRVARAFVIDFLEVHW
FDKATFPSFNVADAAICIGVGMLIIDSFVRKEKPAQAPTQA

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 22814; Mature: 22683

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKYIILLAVTLGVIVLDQWTKYLVVRELTTQMEGKESLGERLASMYSEPPPKGFTGMH
CCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
YQPRRHIEISESFFRIRYLENPGAAWGMFRSMPPEARVPLFHVAIIGALILITFSFRKLT
CCCCCCEECCCCEEEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GTDPEEKWALWGLPLVLGGALGNYIDRVARAFVIDFLEVHWFDKATFPSFNVADAAICIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VGMLIIDSFVRKEKPAQAPTQA
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PRKYIILLAVTLGVIVLDQWTKYLVVRELTTQMEGKESLGERLASMYSEPPPKGFTGMH
CCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCC
YQPRRHIEISESFFRIRYLENPGAAWGMFRSMPPEARVPLFHVAIIGALILITFSFRKLT
CCCCCCEECCCCEEEEEEECCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GTDPEEKWALWGLPLVLGGALGNYIDRVARAFVIDFLEVHWFDKATFPSFNVADAAICIG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
VGMLIIDSFVRKEKPAQAPTQA
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA