Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 108757607

GI number: 108757607

Start: 434755

End: 435351

Strand: Direct

Name: lspA [H]

Synonym: MXAN_0368

Alternate gene names: 108757607

Gene position: 434755-435351 (Clockwise)

Preceding gene: 108761449

Following gene: 108762828

Centisome position: 4.76

GC content: 66.33

Gene sequence:

>597_bases
ATGAAAGTCTCCCATCGATTCGTCCTCCTCGTGATTGTCGCGGTGCTCGCCGCAGACCAGGTGACCAAGTACCTAGCTGT
CTCTCGGCTGACGGATGCCCTGGATGGGCGGGAAGGCCTGGCGCGGGTGACGGGCTTCGTCACCGAGCAGAACCTGGACA
ACCGCCCGCCGCCCGAGGACGGCTCGTACCGGGTGTTGCGGCCCTATCGCTTCATCGAGGACTACTGGCACTTCCGCTAC
GTGGAGAACCCGGGCGCGGCCTGGGGCATCTTCGGCGACATGCCCGAGGGCGTGCGACGCCTCTTCTTCCTCGTGGTGAG
TCTGGCGGCCATGGGCTTCATCTTCGTGATGTACCGGCGCACGCCCATGGAGCAGCGGCTGGCCCGGGTGGCCCTGGCGC
TGGTGACGGGTGGTGCGCTGGGCAACTTCGTGGACCGGTTGTTGCGTGGCTACGTCATCGACTTCATCGACTGGCACTGG
CGCAACCAGCCGGGGATGCGCTGGCCGACCTTCAACGTGGCGGACGTGGCCATCAGCGTCGGGGTGGGTCTCATGCTGCT
GGACTCGCTGCGGGCGCCGAAAAGCCCCAATCCGTGA

Upstream 100 bases:

>100_bases
CCGTGCTGGCCGGGAGATGGAGCGAGCGGACAGGGAAGGGGCGGGTGGGCACTCTTCGTTGTCAGGACTCCGAGGAGCGG
GATAGAGGAGGGCGCGCGAC

Downstream 100 bases:

>100_bases
CGGGCGGGCGGCGGCTGGTGTAAGTCCCGGCCCGTGCCGCGCAAATACATCATCCTCCTCGCCGTCACCCTTGGCGTCAT
CGTGCTCGACCAGTGGACGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MKVSHRFVLLVIVAVLAADQVTKYLAVSRLTDALDGREGLARVTGFVTEQNLDNRPPPEDGSYRVLRPYRFIEDYWHFRY
VENPGAAWGIFGDMPEGVRRLFFLVVSLAAMGFIFVMYRRTPMEQRLARVALALVTGGALGNFVDRLLRGYVIDFIDWHW
RNQPGMRWPTFNVADVAISVGVGLMLLDSLRAPKSPNP

Sequences:

>Translated_198_residues
MKVSHRFVLLVIVAVLAADQVTKYLAVSRLTDALDGREGLARVTGFVTEQNLDNRPPPEDGSYRVLRPYRFIEDYWHFRY
VENPGAAWGIFGDMPEGVRRLFFLVVSLAAMGFIFVMYRRTPMEQRLARVALALVTGGALGNFVDRLLRGYVIDFIDWHW
RNQPGMRWPTFNVADVAISVGVGLMLLDSLRAPKSPNP
>Mature_198_residues
MKVSHRFVLLVIVAVLAADQVTKYLAVSRLTDALDGREGLARVTGFVTEQNLDNRPPPEDGSYRVLRPYRFIEDYWHFRY
VENPGAAWGIFGDMPEGVRRLFFLVVSLAAMGFIFVMYRRTPMEQRLARVALALVTGGALGNFVDRLLRGYVIDFIDWHW
RNQPGMRWPTFNVADVAISVGVGLMLLDSLRAPKSPNP

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=127, Percent_Identity=37.7952755905512, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 22457; Mature: 22457

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVSHRFVLLVIVAVLAADQVTKYLAVSRLTDALDGREGLARVTGFVTEQNLDNRPPPED
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
GSYRVLRPYRFIEDYWHFRYVENPGAAWGIFGDMPEGVRRLFFLVVSLAAMGFIFVMYRR
CCEEEEHHHHHHHHHHHHEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TPMEQRLARVALALVTGGALGNFVDRLLRGYVIDFIDWHWRNQPGMRWPTFNVADVAISV
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
GVGLMLLDSLRAPKSPNP
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKVSHRFVLLVIVAVLAADQVTKYLAVSRLTDALDGREGLARVTGFVTEQNLDNRPPPED
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
GSYRVLRPYRFIEDYWHFRYVENPGAAWGIFGDMPEGVRRLFFLVVSLAAMGFIFVMYRR
CCEEEEHHHHHHHHHHHHEEECCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
TPMEQRLARVALALVTGGALGNFVDRLLRGYVIDFIDWHWRNQPGMRWPTFNVADVAISV
CCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
GVGLMLLDSLRAPKSPNP
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA