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The map label for this gene is pdxA [H]

Identifier: 108762691

GI number: 108762691

Start: 530459

End: 531499

Strand: Reverse

Name: pdxA [H]

Synonym: MXAN_0467

Alternate gene names: 108762691

Gene position: 531499-530459 (Counterclockwise)

Preceding gene: 108758581

Following gene: 108758157

Centisome position: 5.82

GC content: 72.33

Gene sequence:

>1041_bases
GTGGGCCTTCCGCACGTCGGAATCTCCCTGGGGGACGTGTCGGGCATCGGGCCGGAGGTGACGGCCGCGGCCCTGACGAA
GCCCTCCGTGCGCAAGGTGCTCGTCCCCGTCATCTTCGGGGACGGGCCCACGCTGGCGCGCTTCCCCGCCTTCCGCCGCT
ATGCCCGCGTGGAGCCCTCCGCCCTGGGCCGCGTGGAAGGCCCCACCGTGGTGGAGGTAACGCGGCTCGCGGAGAAGGAC
CGCGTGCCCGGAGAGCCCTCGCGCGAGGGCGGCCGCGCGCAATACGCCTTCGTGACGGCGGCCATCGACGCGATGCGGGC
CGGACACGTGGACGCGCTGTGCACCGCGCCCGTGTCGAAGGAGCAGATTTCCCGCGCGGGCATCCCCTTCATGGGTCACA
CCGAAGTGCTGGCGGAGGCCTTCGGCGTGGACGTGATGATGTTGATGGATGGGCCTCGCGTGCGCGTGGCGCTCGCCACC
AACCACGTTCCCCTGGCGGACCTGCCGCGCCTGCTCACCGTGGACGGACTGACCGCGCAACTCAAGCTGCTGTCGCGCAG
CCTGGAGCCGGTGGTGGGCCACAAGCCGCGCATCGCCGTGCTGGGGCTCAACCCGCACGCGGGCGAAGGTGGGCTCCTGG
GACGCGAAGAGGTGGAGGTGATTGGCCCCGCCATCCGCAAGGCCCGCGCGGCCCGGGTGGACGCGAATGGGCCCATCCCC
GCGGACGGGCTCTTCGCGAAGCCCGACGAGGTGGGCGCGCGCTACGACGCGGTGCTGGCCATGTACCACGACCAGGGGCT
CATCCCGGCCAAGGCGCTGGACTTCGAGCGCACGGTGAACGTGACGCTGGGCCTGCCCGTGCCGCGCACGTCTCCCGACC
ACGGCACGGCCTACGCCATCGCCGGCAAGGGTGAGGCGAGCTGCGTGCCCATGGTGGAAGCACTGCTCAAGGCCGCCCAG
CTCGCGGGGGCCCGTCTTGCACACCAGGCAACCGGGCGACGTGCTCGGCCAGGTCCGCTCCGTCCTTCGCCGGGTCGATG
A

Upstream 100 bases:

>100_bases
TGGAGGGCAAGCTGCTCCAGGAGAAGACGGAGAAGTTCCTCGACCAGTACGTGCAGGAACTGCGGCAGAAGGCCAACGTC
GACGTGAAGCTGTAGCCGCC

Downstream 100 bases:

>100_bases
GCTGAACGTGTGCCCCGGAGCCACTGTCCGGGACCACCAGCACGCTCACGAGGCCCCGGGGACACTCCCCCAGACAGCCT
GACGCCATCACCCGCGTCCG

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MGLPHVGISLGDVSGIGPEVTAAALTKPSVRKVLVPVIFGDGPTLARFPAFRRYARVEPSALGRVEGPTVVEVTRLAEKD
RVPGEPSREGGRAQYAFVTAAIDAMRAGHVDALCTAPVSKEQISRAGIPFMGHTEVLAEAFGVDVMMLMDGPRVRVALAT
NHVPLADLPRLLTVDGLTAQLKLLSRSLEPVVGHKPRIAVLGLNPHAGEGGLLGREEVEVIGPAIRKARAARVDANGPIP
ADGLFAKPDEVGARYDAVLAMYHDQGLIPAKALDFERTVNVTLGLPVPRTSPDHGTAYAIAGKGEASCVPMVEALLKAAQ
LAGARLAHQATGRRARPGPLRPSPGR

Sequences:

>Translated_346_residues
MGLPHVGISLGDVSGIGPEVTAAALTKPSVRKVLVPVIFGDGPTLARFPAFRRYARVEPSALGRVEGPTVVEVTRLAEKD
RVPGEPSREGGRAQYAFVTAAIDAMRAGHVDALCTAPVSKEQISRAGIPFMGHTEVLAEAFGVDVMMLMDGPRVRVALAT
NHVPLADLPRLLTVDGLTAQLKLLSRSLEPVVGHKPRIAVLGLNPHAGEGGLLGREEVEVIGPAIRKARAARVDANGPIP
ADGLFAKPDEVGARYDAVLAMYHDQGLIPAKALDFERTVNVTLGLPVPRTSPDHGTAYAIAGKGEASCVPMVEALLKAAQ
LAGARLAHQATGRRARPGPLRPSPGR
>Mature_345_residues
GLPHVGISLGDVSGIGPEVTAAALTKPSVRKVLVPVIFGDGPTLARFPAFRRYARVEPSALGRVEGPTVVEVTRLAEKDR
VPGEPSREGGRAQYAFVTAAIDAMRAGHVDALCTAPVSKEQISRAGIPFMGHTEVLAEAFGVDVMMLMDGPRVRVALATN
HVPLADLPRLLTVDGLTAQLKLLSRSLEPVVGHKPRIAVLGLNPHAGEGGLLGREEVEVIGPAIRKARAARVDANGPIPA
DGLFAKPDEVGARYDAVLAMYHDQGLIPAKALDFERTVNVTLGLPVPRTSPDHGTAYAIAGKGEASCVPMVEALLKAAQL
AGARLAHQATGRRARPGPLRPSPGR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=240, Percent_Identity=44.5833333333333, Blast_Score=170, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36272; Mature: 36140

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLPHVGISLGDVSGIGPEVTAAALTKPSVRKVLVPVIFGDGPTLARFPAFRRYARVEPS
CCCCCCCEEECCCCCCCCCHHHHHHCCCCHHEEEEEEEECCCCCHHHHHHHHHHHCCCHH
ALGRVEGPTVVEVTRLAEKDRVPGEPSREGGRAQYAFVTAAIDAMRAGHVDALCTAPVSK
HCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCH
EQISRAGIPFMGHTEVLAEAFGVDVMMLMDGPRVRVALATNHVPLADLPRLLTVDGLTAQ
HHHHHCCCCCCCHHHHHHHHHCCEEEEEECCCEEEEEEEECCCCHHHCCCEEEECCHHHH
LKLLSRSLEPVVGHKPRIAVLGLNPHAGEGGLLGREEVEVIGPAIRKARAARVDANGPIP
HHHHHHHCCHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
ADGLFAKPDEVGARYDAVLAMYHDQGLIPAKALDFERTVNVTLGLPVPRTSPDHGTAYAI
CCCCCCCCHHHCCHHHEEEEEECCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCCCEEEE
AGKGEASCVPMVEALLKAAQLAGARLAHQATGRRARPGPLRPSPGR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GLPHVGISLGDVSGIGPEVTAAALTKPSVRKVLVPVIFGDGPTLARFPAFRRYARVEPS
CCCCCCEEECCCCCCCCCHHHHHHCCCCHHEEEEEEEECCCCCHHHHHHHHHHHCCCHH
ALGRVEGPTVVEVTRLAEKDRVPGEPSREGGRAQYAFVTAAIDAMRAGHVDALCTAPVSK
HCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCCCEEECCCCCH
EQISRAGIPFMGHTEVLAEAFGVDVMMLMDGPRVRVALATNHVPLADLPRLLTVDGLTAQ
HHHHHCCCCCCCHHHHHHHHHCCEEEEEECCCEEEEEEEECCCCHHHCCCEEEECCHHHH
LKLLSRSLEPVVGHKPRIAVLGLNPHAGEGGLLGREEVEVIGPAIRKARAARVDANGPIP
HHHHHHHCCHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
ADGLFAKPDEVGARYDAVLAMYHDQGLIPAKALDFERTVNVTLGLPVPRTSPDHGTAYAI
CCCCCCCCHHHCCHHHEEEEEECCCCCCCHHHCCCCEEEEEEEECCCCCCCCCCCCEEEE
AGKGEASCVPMVEALLKAAQLAGARLAHQATGRRARPGPLRPSPGR
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA