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The map label for this gene is rtcA [H]

Identifier: 108762499

GI number: 108762499

Start: 6228489

End: 6229505

Strand: Reverse

Name: rtcA [H]

Synonym: MXAN_4981

Alternate gene names: 108762499

Gene position: 6229505-6228489 (Counterclockwise)

Preceding gene: 108761016

Following gene: 108761725

Centisome position: 68.16

GC content: 69.91

Gene sequence:

>1017_bases
ATGGTGCGCATCGATGGTTCATTGGGTGAGGGCGGGGGGCAGGTGCTGCGCACCTCGCTGTCGCTGTCGCTGGTGACGGG
CAAGCCCTTCACCATCCAGAACATCCGCGCGGGTCGGAAGAAGCCGGGCCTGCTGCGCCAGCACCTGACGTCGGTGAAGG
CCGCGGAGGCCGTGGGGGCCGCGGAGGTGTCGGGCGCGGAGCTCGGCTCGCGAGAGCTGACCTTCCGGCCGAGTGCCCTG
GCCGCGGGGAACTACCACTTCGCGGTGGGCACCGCGGGCAGCGCGACGCTGGTGCTCCAGACGGTGCTTCCGGCGCTGCT
CCTGGCGAAGGGGCCTTCCACGCTGATGTTGGAGGGGGGAACGCACAACCCCATGGCGCCACCGTTCGACTTCCTCCAGC
GGGCGTATCTGCCGCTGGTCCGTCGCATGGGGCCGTCCGTGGAGGCGACCCTGGAGCGTGCCGGTTTCTTCCCTGCCGGG
GGCGGGCGGTTCCGGGTCGACGTGCGACCCGCGCCGTTGAAGCCGCTGCACCTGCTGGAGCGGGGGCGCGTGGTCCGTCG
CGACCTGAAGGCCGTGATTGCGATGATTCCGTTCGACGTGGCGCAGCGCGAGCTGGGCACGGCGGGAGCGGCGCTGAAGT
GGCGGCCCGATGAACTCCGGACGGAGGAACTGAAGCGTCCGCTGGGGCCCGGCAACGTGCTGGTCGCCGAAGTGGAGAGC
GAGCACGTGACAGAGGTCTTCACCGGCTTTGGTGAGCGGGGGAAGCGGGCGGAGGCCGTGGCCGGACAGGTCGCTGAAGA
GGTGAAGCGCTACCTCGACGCGGACGTGCCGGTGGGCGAGCACCTGTGTGACCAACTGCTGCTCCTCGTGGCGCTGGCGA
AGGGCGGCGTGTTCCGCACGCTGCCATTGGATGGGCATGCCGAGACGCAGCTCCAAACCATCGCCCAGTTCCTGGATGTG
AAGGTGGAGGTGCGGGAGGTGTCTCGCGAGGTTCGCGAGGTGGAGGTCCGCGCCTGA

Upstream 100 bases:

>100_bases
AAAGGCCGCCAGGATGGGGACGCGGGCGCCGCTATTTTCACGGGGGTGTCAGTGCGTGCCGGGTGGTTCGTGAGTCGCGA
GCAGCAAGGAGGAAGTCGTC

Downstream 100 bases:

>100_bases
GCCCCAGGGGCGCGTCCGCTTGCGGGCGGCCCTGGGGCTGAGCATCGCGCGCTCCGCTCGGAGGGCAGTCAGGCCCCATG
GCGGGTGGGCATCTCCGTGG

Product: RNA 3'-terminal-phosphate cyclase

Products: NA

Alternate protein names: RNA cyclase; RNA-3'-phosphate cyclase [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MVRIDGSLGEGGGQVLRTSLSLSLVTGKPFTIQNIRAGRKKPGLLRQHLTSVKAAEAVGAAEVSGAELGSRELTFRPSAL
AAGNYHFAVGTAGSATLVLQTVLPALLLAKGPSTLMLEGGTHNPMAPPFDFLQRAYLPLVRRMGPSVEATLERAGFFPAG
GGRFRVDVRPAPLKPLHLLERGRVVRRDLKAVIAMIPFDVAQRELGTAGAALKWRPDELRTEELKRPLGPGNVLVAEVES
EHVTEVFTGFGERGKRAEAVAGQVAEEVKRYLDADVPVGEHLCDQLLLLVALAKGGVFRTLPLDGHAETQLQTIAQFLDV
KVEVREVSREVREVEVRA

Sequences:

>Translated_338_residues
MVRIDGSLGEGGGQVLRTSLSLSLVTGKPFTIQNIRAGRKKPGLLRQHLTSVKAAEAVGAAEVSGAELGSRELTFRPSAL
AAGNYHFAVGTAGSATLVLQTVLPALLLAKGPSTLMLEGGTHNPMAPPFDFLQRAYLPLVRRMGPSVEATLERAGFFPAG
GGRFRVDVRPAPLKPLHLLERGRVVRRDLKAVIAMIPFDVAQRELGTAGAALKWRPDELRTEELKRPLGPGNVLVAEVES
EHVTEVFTGFGERGKRAEAVAGQVAEEVKRYLDADVPVGEHLCDQLLLLVALAKGGVFRTLPLDGHAETQLQTIAQFLDV
KVEVREVSREVREVEVRA
>Mature_338_residues
MVRIDGSLGEGGGQVLRTSLSLSLVTGKPFTIQNIRAGRKKPGLLRQHLTSVKAAEAVGAAEVSGAELGSRELTFRPSAL
AAGNYHFAVGTAGSATLVLQTVLPALLLAKGPSTLMLEGGTHNPMAPPFDFLQRAYLPLVRRMGPSVEATLERAGFFPAG
GGRFRVDVRPAPLKPLHLLERGRVVRRDLKAVIAMIPFDVAQRELGTAGAALKWRPDELRTEELKRPLGPGNVLVAEVES
EHVTEVFTGFGERGKRAEAVAGQVAEEVKRYLDADVPVGEHLCDQLLLLVALAKGGVFRTLPLDGHAETQLQTIAQFLDV
KVEVREVSREVREVEVRA

Specific function: Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps:(A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA- N3'PP5'A;

COG id: COG0430

COG function: function code A; RNA 3'-terminal phosphate cyclase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4506589, Length=345, Percent_Identity=34.7826086956522, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI195927044, Length=358, Percent_Identity=33.5195530726257, Blast_Score=172, Evalue=5e-43,
Organism=Escherichia coli, GI48994937, Length=327, Percent_Identity=49.5412844036697, Blast_Score=296, Evalue=1e-81,
Organism=Drosophila melanogaster, GI18543269, Length=335, Percent_Identity=32.5373134328358, Blast_Score=161, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013791
- InterPro:   IPR000228
- InterPro:   IPR020719
- InterPro:   IPR013796
- InterPro:   IPR020723
- InterPro:   IPR017770
- InterPro:   IPR013792 [H]

Pfam domain/function: PF01137 RTC; PF05189 RTC_insert [H]

EC number: =6.5.1.4 [H]

Molecular weight: Translated: 36358; Mature: 36358

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIDGSLGEGGGQVLRTSLSLSLVTGKPFTIQNIRAGRKKPGLLRQHLTSVKAAEAVGA
CEEECCCCCCCCHHHHHHHHEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
AEVSGAELGSRELTFRPSALAAGNYHFAVGTAGSATLVLQTVLPALLLAKGPSTLMLEGG
HHCCCCCCCCCCEEECCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECC
THNPMAPPFDFLQRAYLPLVRRMGPSVEATLERAGFFPAGGGRFRVDVRPAPLKPLHLLE
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHH
RGRVVRRDLKAVIAMIPFDVAQRELGTAGAALKWRPDELRTEELKRPLGPGNVLVAEVES
HHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEECCH
EHVTEVFTGFGERGKRAEAVAGQVAEEVKRYLDADVPVGEHLCDQLLLLVALAKGGVFRT
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEE
LPLDGHAETQLQTIAQFLDVKVEVREVSREVREVEVRA
ECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVRIDGSLGEGGGQVLRTSLSLSLVTGKPFTIQNIRAGRKKPGLLRQHLTSVKAAEAVGA
CEEECCCCCCCCHHHHHHHHEEEEECCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCC
AEVSGAELGSRELTFRPSALAAGNYHFAVGTAGSATLVLQTVLPALLLAKGPSTLMLEGG
HHCCCCCCCCCCEEECCCCEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECC
THNPMAPPFDFLQRAYLPLVRRMGPSVEATLERAGFFPAGGGRFRVDVRPAPLKPLHLLE
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHH
RGRVVRRDLKAVIAMIPFDVAQRELGTAGAALKWRPDELRTEELKRPLGPGNVLVAEVES
HHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEEECCHHHHHHHHHCCCCCCCEEEEECCH
EHVTEVFTGFGERGKRAEAVAGQVAEEVKRYLDADVPVGEHLCDQLLLLVALAKGGVFRT
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCEEEE
LPLDGHAETQLQTIAQFLDVKVEVREVSREVREVEVRA
ECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA