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The map label for this gene is sugE [H]

Identifier: 108762496

GI number: 108762496

Start: 446752

End: 447081

Strand: Direct

Name: sugE [H]

Synonym: MXAN_0384

Alternate gene names: 108762496

Gene position: 446752-447081 (Clockwise)

Preceding gene: 108763423

Following gene: 108761762

Centisome position: 4.89

GC content: 62.42

Gene sequence:

>330_bases
ATGTCGTGGCTGCTTGTTCTCGTTGCTGGGTTGCTGGAGACGTGCTGGGCTGTGGGCCTCAAGTATACGCAGGGCTTCAC
CCGGCCTTGGCCCAGTCTCTTTGTTGCCGTCACGTTGATTAGCAGCTTGGCGCTGCTGTCCATTGCGATGCGCACGCTGC
CGGCCGGAACTGCGTACGCGGTTTGGGTTGGAATTGGGGCCTTGGGCGCCGCGCTTGTTGGCATCGTGCTCTTCCGTGAG
CCGGCCACACTGGGGCGCTTCTTCTTCCTCGGACTCATGGTCGTCTCTGTCATCGGCCTGAAGTTCACCAGCGGCGGGGA
CGCGCACTAG

Upstream 100 bases:

>100_bases
GCCAGCCGCACCAGCTGCAATCAGTTCAGATTGCAGCCCTGCCCGGACGAGATGCGCCGTACCCGGTTACGTAAGACGAC
GCCCTGACCAGGGGTGCGTC

Downstream 100 bases:

>100_bases
GGGCTGTCTATCCGAGCGCGCGCAGTACGTATCGAGCCCTGGCGACGACGCGCGCTGCGCCTATCGGCTGAGCCTCATCA
ACGCCATGGTGGCGCACCAC

Product: quaternary ammonium compound-resistance protein SugE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSWLLVLVAGLLETCWAVGLKYTQGFTRPWPSLFVAVTLISSLALLSIAMRTLPAGTAYAVWVGIGALGAALVGIVLFRE
PATLGRFFFLGLMVVSVIGLKFTSGGDAH

Sequences:

>Translated_109_residues
MSWLLVLVAGLLETCWAVGLKYTQGFTRPWPSLFVAVTLISSLALLSIAMRTLPAGTAYAVWVGIGALGAALVGIVLFRE
PATLGRFFFLGLMVVSVIGLKFTSGGDAH
>Mature_108_residues
SWLLVLVAGLLETCWAVGLKYTQGFTRPWPSLFVAVTLISSLALLSIAMRTLPAGTAYAVWVGIGALGAALVGIVLFREP
ATLGRFFFLGLMVVSVIGLKFTSGGDAH

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=104, Percent_Identity=55.7692307692308, Blast_Score=113, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 11514; Mature: 11383

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLLVLVAGLLETCWAVGLKYTQGFTRPWPSLFVAVTLISSLALLSIAMRTLPAGTAYA
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VWVGIGALGAALVGIVLFREPATLGRFFFLGLMVVSVIGLKFTSGGDAH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SWLLVLVAGLLETCWAVGLKYTQGFTRPWPSLFVAVTLISSLALLSIAMRTLPAGTAYA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VWVGIGALGAALVGIVLFREPATLGRFFFLGLMVVSVIGLKFTSGGDAH
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA