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The map label for this gene is ndh [H]

Identifier: 108761762

GI number: 108761762

Start: 447225

End: 448637

Strand: Direct

Name: ndh [H]

Synonym: MXAN_0385

Alternate gene names: 108761762

Gene position: 447225-448637 (Clockwise)

Preceding gene: 108762496

Following gene: 108757843

Centisome position: 4.89

GC content: 71.41

Gene sequence:

>1413_bases
ATGGACCCCATCACGCCTCCGCTCGCCCTCGGCCAGAAGCACGTCGTCGTGCTGGGTGCGGGCTTCGCCGGACTCACGGC
CGCCAAGGCGCTCGCGCGCCACTCGGCGCTGTACGTGACGGTCCTCGACCAGCGCAACCATCACCTCTTCCAGCCGCTGC
TCTACCAGGTGGCTACTAGCGGACTGAGCCCCGCGGACATCGCGGTGCCCATCCGCTCGCAGTTCGCACGCAAGCCCAAT
GTGTCGGTGCACTTGGGCCGCGTCACGTGGGTGAACCTCAAGGAACGCTGGGTGGGCGGTGAGGGCGACGTGCGGCTGCG
CTACGACTACCTCGTCATCGCGTGCGGCGCGCAGCACAGCTACTTCGGCAAGTCGGAGTGGGAGGACTTCGCCCCGGGAC
TCAAGACGCTGGAGCAGGCGACGGAGTTGCGCCGCCGCATCCTCAGCGCCTTCGAGCAGGCGGAAAACGAGCGCGACGCC
GAGCGCCAGCGCGCGCTCCTGAGCTTCGTCGTCGTGGGCGCGGGCCCGACGGGCGTGGAACTGGCGGGCGCCATCGCGGA
CATCAGCCGCACGGTGCTGGTGCGCGATTTCCGTCGCATCAAACCGTCCCGCGCGCGCGTCTTCCTCGTGGAGGCGGGCC
CACGCATTCTGCCGTCCTTCAGCGAGAAGCTGGGAGTGCGTGCGCACCGCGACCTTGCGGCCCTGGGCGTGGAAGTGCGC
ACGGAGGCACGCGTGACGGCGGTGGACGCCGAGGGTGTGATGCTCGGCTCCGAGCGCCTGGCCTCGCGCACGGTGGTGTG
GGCTGCAGGTGTGCAGGCCGAGTACCTCACGCGCGGGCTCGGCGTGCCGCTGGACCGCGCGGGGCGCGTGCAGGTGGCGG
CGGATCTCACGCTGCCCGGCCACCCGGAGGTCTTCGCCGCGGGTGACGTGGCCCACGTGGAGCTGGACGGTAAGCTCGTG
CCCGGTGTCGCGCCTGCGGCCATGCAGATGGGCCGGGCCGTGGCGCGCAACGTCCTCGCGGACCTGCGCGGCCGCCCCCG
CACGCCCTTCCGCTACAAGGACAAGGGCGCGATGGCCACCATCGGCAAGCACCGGGCCATCGCGGAGACGGGCCGCGCCA
GGCTGACGGGCTTCGTCGCGTGGGTGGCGTGGCTCTTCATCCACGTCTGGTACCTGGTGGGCTTCAAGAACCGCTTCGGC
GTGTTCGTCACGTGGGTGTGGAGTTACCTGTTCAGCACGCGCGGCGCGCGGCTCATCACGGAGCGCGAGTGGCGGTTGAG
TCCGAAGGTCGCGTCTGAGCGCGCGCCGCACGCGGGCAAGGTGACGGCGGGCGACCCCACGGCGCCCACCAGTGATGCAC
GGCCGCCGGACGGGACGACGACTACGGCCGCTGCCGCCCTCGTCGCGGACTGA

Upstream 100 bases:

>100_bases
GACGACGCGCGCTGCGCCTATCGGCTGAGCCTCATCAACGCCATGGTGGCGCACCACGGTTACTCGGCCGTGTGCGACGG
CCAGGTGAAGGAGATGTCCC

Downstream 100 bases:

>100_bases
AGATGATGTCACCCCGCGAATTCCGTACTGCTAATTCCCAACCCCGAGCTGTCCGATTTGATGGGGGCAACTCCAGGCGC
GCTCCTGCTGGGGTTTCGCT

Product: pyridine nucleotide-disulfide oxidoreductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MDPITPPLALGQKHVVVLGAGFAGLTAAKALARHSALYVTVLDQRNHHLFQPLLYQVATSGLSPADIAVPIRSQFARKPN
VSVHLGRVTWVNLKERWVGGEGDVRLRYDYLVIACGAQHSYFGKSEWEDFAPGLKTLEQATELRRRILSAFEQAENERDA
ERQRALLSFVVVGAGPTGVELAGAIADISRTVLVRDFRRIKPSRARVFLVEAGPRILPSFSEKLGVRAHRDLAALGVEVR
TEARVTAVDAEGVMLGSERLASRTVVWAAGVQAEYLTRGLGVPLDRAGRVQVAADLTLPGHPEVFAAGDVAHVELDGKLV
PGVAPAAMQMGRAVARNVLADLRGRPRTPFRYKDKGAMATIGKHRAIAETGRARLTGFVAWVAWLFIHVWYLVGFKNRFG
VFVTWVWSYLFSTRGARLITEREWRLSPKVASERAPHAGKVTAGDPTAPTSDARPPDGTTTTAAAALVAD

Sequences:

>Translated_470_residues
MDPITPPLALGQKHVVVLGAGFAGLTAAKALARHSALYVTVLDQRNHHLFQPLLYQVATSGLSPADIAVPIRSQFARKPN
VSVHLGRVTWVNLKERWVGGEGDVRLRYDYLVIACGAQHSYFGKSEWEDFAPGLKTLEQATELRRRILSAFEQAENERDA
ERQRALLSFVVVGAGPTGVELAGAIADISRTVLVRDFRRIKPSRARVFLVEAGPRILPSFSEKLGVRAHRDLAALGVEVR
TEARVTAVDAEGVMLGSERLASRTVVWAAGVQAEYLTRGLGVPLDRAGRVQVAADLTLPGHPEVFAAGDVAHVELDGKLV
PGVAPAAMQMGRAVARNVLADLRGRPRTPFRYKDKGAMATIGKHRAIAETGRARLTGFVAWVAWLFIHVWYLVGFKNRFG
VFVTWVWSYLFSTRGARLITEREWRLSPKVASERAPHAGKVTAGDPTAPTSDARPPDGTTTTAAAALVAD
>Mature_470_residues
MDPITPPLALGQKHVVVLGAGFAGLTAAKALARHSALYVTVLDQRNHHLFQPLLYQVATSGLSPADIAVPIRSQFARKPN
VSVHLGRVTWVNLKERWVGGEGDVRLRYDYLVIACGAQHSYFGKSEWEDFAPGLKTLEQATELRRRILSAFEQAENERDA
ERQRALLSFVVVGAGPTGVELAGAIADISRTVLVRDFRRIKPSRARVFLVEAGPRILPSFSEKLGVRAHRDLAALGVEVR
TEARVTAVDAEGVMLGSERLASRTVVWAAGVQAEYLTRGLGVPLDRAGRVQVAADLTLPGHPEVFAAGDVAHVELDGKLV
PGVAPAAMQMGRAVARNVLADLRGRPRTPFRYKDKGAMATIGKHRAIAETGRARLTGFVAWVAWLFIHVWYLVGFKNRFG
VFVTWVWSYLFSTRGARLITEREWRLSPKVASERAPHAGKVTAGDPTAPTSDARPPDGTTTTAAAALVAD

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=389, Percent_Identity=26.4781491002571, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6323794, Length=462, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323515, Length=467, Percent_Identity=25.9100642398287, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6320118, Length=465, Percent_Identity=28.3870967741935, Blast_Score=98, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 51082; Mature: 51082

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPITPPLALGQKHVVVLGAGFAGLTAAKALARHSALYVTVLDQRNHHLFQPLLYQVATS
CCCCCCCHHCCCCEEEEEECCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHC
GLSPADIAVPIRSQFARKPNVSVHLGRVTWVNLKERWVGGEGDVRLRYDYLVIACGAQHS
CCCCCCEEEEHHHHHCCCCCCEEEEEEEEEEEHHHHCCCCCCCEEEEEEEEEEEECCCCC
YFGKSEWEDFAPGLKTLEQATELRRRILSAFEQAENERDAERQRALLSFVVVGAGPTGVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEEECCCCCCHH
LAGAIADISRTVLVRDFRRIKPSRARVFLVEAGPRILPSFSEKLGVRAHRDLAALGVEVR
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHCCHHHCCHHHHCCEEE
TEARVTAVDAEGVMLGSERLASRTVVWAAGVQAEYLTRGLGVPLDRAGRVQVAADLTLPG
CCCEEEEECCCCEEECCHHHHCCEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEEECCCC
HPEVFAAGDVAHVELDGKLVPGVAPAAMQMGRAVARNVLADLRGRPRTPFRYKDKGAMAT
CCCEEECCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEE
IGKHRAIAETGRARLTGFVAWVAWLFIHVWYLVGFKNRFGVFVTWVWSYLFSTRGARLIT
HHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEE
EREWRLSPKVASERAPHAGKVTAGDPTAPTSDARPPDGTTTTAAAALVAD
CCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHEECC
>Mature Secondary Structure
MDPITPPLALGQKHVVVLGAGFAGLTAAKALARHSALYVTVLDQRNHHLFQPLLYQVATS
CCCCCCCHHCCCCEEEEEECCHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHC
GLSPADIAVPIRSQFARKPNVSVHLGRVTWVNLKERWVGGEGDVRLRYDYLVIACGAQHS
CCCCCCEEEEHHHHHCCCCCCEEEEEEEEEEEHHHHCCCCCCCEEEEEEEEEEEECCCCC
YFGKSEWEDFAPGLKTLEQATELRRRILSAFEQAENERDAERQRALLSFVVVGAGPTGVE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHEEEECCCCCCHH
LAGAIADISRTVLVRDFRRIKPSRARVFLVEAGPRILPSFSEKLGVRAHRDLAALGVEVR
HHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHCCHHHCCHHHHCCEEE
TEARVTAVDAEGVMLGSERLASRTVVWAAGVQAEYLTRGLGVPLDRAGRVQVAADLTLPG
CCCEEEEECCCCEEECCHHHHCCEEEEECCCCHHHHHHCCCCCCCCCCCEEEEEEECCCC
HPEVFAAGDVAHVELDGKLVPGVAPAAMQMGRAVARNVLADLRGRPRTPFRYKDKGAMAT
CCCEEECCCEEEEEECCEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCEEE
IGKHRAIAETGRARLTGFVAWVAWLFIHVWYLVGFKNRFGVFVTWVWSYLFSTRGARLIT
HHCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEE
EREWRLSPKVASERAPHAGKVTAGDPTAPTSDARPPDGTTTTAAAALVAD
CCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]