BacMap

Definition	Myxococcus xanthus DK 1622 chromosome, complete genome.
Accession	NC_008095
Length	9,139,763

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The map label for this gene is fadH [H]

Identifier: 108762350

GI number: 108762350

Start: 87914

End: 88792

Strand: Reverse

Name: fadH [H]

Synonym: MXAN_0078

Alternate gene names: 108762350

Gene position: 88792-87914 (Counterclockwise)

Preceding gene: 108761552

Following gene: 108760307

Centisome position: 0.97

GC content: 68.37

Gene sequence:

>879_bases
ATGGGCTACCGCTCTCTCTTCGCACCGGGCTGTTTCAGCAACCGCACCATCGTCGTCACCGGCGGCGGCAGTGGCATTGG
CCGCTGCACCGCGCACGAGCTGGCCGCGCTGGGCGCCAACGTCGTCCTGGTGGGCCGCAAGCCCGACAAGCTGGAGGCCG
TCGCGCGGGAAATCCAGGAGGACGGCGGCAAGGTGTCCTTCGAGGTGCTCGACATCCGCGACGAGGAGGGCGTGAAGGCC
ACCGTGGCGCGCATCATCGCCGCGCACGGCCCCATCCACGGCCTGGTCAACAACGCGGGCGGGCAGTTCCCCTCGCCGCT
GTCGGCCATCTCCAAGAAGGGCTTTGACGCGGTGGTGTCCACCAACCTCACCGGCGGCTTCCTGATGGCGCGGGAAGTCT
ATCTCCAATCCATGAGCAGCCACGGGGGCTCCATCGTCAACATGCTCGCGGACTCGTGGGGCGGCATGCCGGGCATGGGG
CACTCCGGCGCGGCGCGCATGGGCATGCTCAACCTGACGCAGACGGCCGCCGTGGAGTGGGCCGCGTCTGGCGTGCGCGT
GAATGCCGTGGCGCCCGGCTGGGTGGCCTCCAGCGGCATGGACAGCTACAAGGACGAGGGCGTGCGGGCGATGATTCCCC
TCCTCAAGAAGGAGGTGCCGCTCCAGCGGCTCGCCACCGAATCCGAGGTGAGCGCCGCCATCGTCTTCCTGCTCACCGAC
GCTGCGGCCTTCATCACCGGCGACGTCATCAAGATTGATGGTGGCGCGTCGTGCAACACCAAGATTTTCCCGCTGGAGGA
GACCACCGCCTCCAAGCCCTACGAGGGATTCCACCGCGCGTCGGCGCCGCGCATCCTCGGGGGTGAGTCGAAGGAGTAG

Upstream 100 bases:

>100_bases
CGCTGGGCGCTCACCCTGGACGAGGCCCTGAGCGCCCGGCGCACCCGCAGAGGCTGAGGACCGCAGGTTTCATGAACGAC
CTCCACATCAGGAGCTGACC

Downstream 100 bases:

>100_bases
GAACGACACCCCGCTTCCGCCAACGTCGCGCGGAAGCGGGGCGCCGCCAGCTCAGAGGCCGTCCGGGTAGCAGAAGCCGT
AGGTGCGGTCGTAGCCGCCA

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MGYRSLFAPGCFSNRTIVVTGGGSGIGRCTAHELAALGANVVLVGRKPDKLEAVAREIQEDGGKVSFEVLDIRDEEGVKA
TVARIIAAHGPIHGLVNNAGGQFPSPLSAISKKGFDAVVSTNLTGGFLMAREVYLQSMSSHGGSIVNMLADSWGGMPGMG
HSGAARMGMLNLTQTAAVEWAASGVRVNAVAPGWVASSGMDSYKDEGVRAMIPLLKKEVPLQRLATESEVSAAIVFLLTD
AAAFITGDVIKIDGGASCNTKIFPLEETTASKPYEGFHRASAPRILGGESKE

Sequences:

>Translated_292_residues
MGYRSLFAPGCFSNRTIVVTGGGSGIGRCTAHELAALGANVVLVGRKPDKLEAVAREIQEDGGKVSFEVLDIRDEEGVKA
TVARIIAAHGPIHGLVNNAGGQFPSPLSAISKKGFDAVVSTNLTGGFLMAREVYLQSMSSHGGSIVNMLADSWGGMPGMG
HSGAARMGMLNLTQTAAVEWAASGVRVNAVAPGWVASSGMDSYKDEGVRAMIPLLKKEVPLQRLATESEVSAAIVFLLTD
AAAFITGDVIKIDGGASCNTKIFPLEETTASKPYEGFHRASAPRILGGESKE
>Mature_291_residues
GYRSLFAPGCFSNRTIVVTGGGSGIGRCTAHELAALGANVVLVGRKPDKLEAVAREIQEDGGKVSFEVLDIRDEEGVKAT
VARIIAAHGPIHGLVNNAGGQFPSPLSAISKKGFDAVVSTNLTGGFLMAREVYLQSMSSHGGSIVNMLADSWGGMPGMGH
SGAARMGMLNLTQTAAVEWAASGVRVNAVAPGWVASSGMDSYKDEGVRAMIPLLKKEVPLQRLATESEVSAAIVFLLTDA
AAFITGDVIKIDGGASCNTKIFPLEETTASKPYEGFHRASAPRILGGESKE

Specific function: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=270, Percent_Identity=41.8518518518518, Blast_Score=204, Evalue=9e-53,
Organism=Homo sapiens, GI10190704, Length=257, Percent_Identity=31.9066147859922, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI4503301, Length=260, Percent_Identity=31.1538461538462, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=27.8884462151394, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=31.0483870967742, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=30.4, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=26.5060240963855, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI126723750, Length=255, Percent_Identity=25.8823529411765, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=27.0916334661355, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI166795268, Length=200, Percent_Identity=32.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4504505, Length=196, Percent_Identity=31.1224489795918, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI33667109, Length=192, Percent_Identity=28.6458333333333, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=28.1385281385281, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI142976729, Length=202, Percent_Identity=26.2376237623762, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI226371731, Length=188, Percent_Identity=27.1276595744681, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI4758504, Length=251, Percent_Identity=27.4900398406374, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI186928839, Length=216, Percent_Identity=31.0185185185185, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=30.9803921568627, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=36.3265306122449, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=28.4552845528455, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=28.2945736434109, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=26.0330578512397, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1789208, Length=244, Percent_Identity=28.2786885245902, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787905, Length=244, Percent_Identity=26.2295081967213, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788459, Length=241, Percent_Identity=26.5560165975104, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI87082160, Length=246, Percent_Identity=26.4227642276423, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789378, Length=263, Percent_Identity=26.2357414448669, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789057, Length=264, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787526, Length=245, Percent_Identity=27.3469387755102, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=26.7676767676768, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=29.8804780876494, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI115534694, Length=252, Percent_Identity=30.5555555555556, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=31.0483870967742, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=30.4347826086957, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=28.8973384030418, Blast_Score=101, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.7709923664122, Blast_Score=95, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559104, Length=261, Percent_Identity=27.2030651340996, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17544670, Length=285, Percent_Identity=29.1228070175439, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=251, Percent_Identity=30.2788844621514, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17561272, Length=265, Percent_Identity=30.9433962264151, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=259, Percent_Identity=26.6409266409266, Blast_Score=85, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=28.3582089552239, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=29.6747967479675, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=28.3524904214559, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=26.8939393939394, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=261, Percent_Identity=27.2030651340996, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=27.710843373494, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=28.0442804428044, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=261, Percent_Identity=27.5862068965517, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=27.8625954198473, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71982365, Length=216, Percent_Identity=29.6296296296296, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17551412, Length=278, Percent_Identity=29.4964028776978, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=26.9961977186312, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=26.1992619926199, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=26.8939393939394, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=28.2868525896414, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=251, Percent_Identity=27.0916334661355, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=257, Percent_Identity=26.0700389105058, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=29.5719844357977, Blast_Score=116, Evalue=5e-27,
Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=30.3664921465969, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21357041, Length=251, Percent_Identity=34.2629482071713, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571526, Length=259, Percent_Identity=35.1351351351351, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.136546184739, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24644339, Length=257, Percent_Identity=31.9066147859922, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24639444, Length=258, Percent_Identity=30.2325581395349, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI24643142, Length=250, Percent_Identity=30.4, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=27.3469387755102, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21357673, Length=195, Percent_Identity=28.7179487179487, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161076933, Length=192, Percent_Identity=31.25, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584748, Length=192, Percent_Identity=31.25, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI17737361, Length=257, Percent_Identity=28.4046692607004, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24584752, Length=202, Percent_Identity=29.2079207920792, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356301, Length=191, Percent_Identity=31.413612565445, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644337, Length=256, Percent_Identity=29.296875, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 30375; Mature: 30244

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYRSLFAPGCFSNRTIVVTGGGSGIGRCTAHELAALGANVVLVGRKPDKLEAVAREIQE
CCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
DGGKVSFEVLDIRDEEGVKATVARIIAAHGPIHGLVNNAGGQFPSPLSAISKKGFDAVVS
CCCEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHCCCCEEEE
TNLTGGFLMAREVYLQSMSSHGGSIVNMLADSWGGMPGMGHSGAARMGMLNLTQTAAVEW
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHCEEEHHHHHHHHH
AASGVRVNAVAPGWVASSGMDSYKDEGVRAMIPLLKKEVPLQRLATESEVSAAIVFLLTD
HHCCEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHCHHHHHHEEEHHHHH
AAAFITGDVIKIDGGASCNTKIFPLEETTASKPYEGFHRASAPRILGGESKE
HHHHHCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GYRSLFAPGCFSNRTIVVTGGGSGIGRCTAHELAALGANVVLVGRKPDKLEAVAREIQE
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHH
DGGKVSFEVLDIRDEEGVKATVARIIAAHGPIHGLVNNAGGQFPSPLSAISKKGFDAVVS
CCCEEEEEEEEECCCCCHHHHHHHHHHHCCCHHHHHHCCCCCCCCHHHHHHHCCCCEEEE
TNLTGGFLMAREVYLQSMSSHGGSIVNMLADSWGGMPGMGHSGAARMGMLNLTQTAAVEW
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCHHHCEEEHHHHHHHHH
AASGVRVNAVAPGWVASSGMDSYKDEGVRAMIPLLKKEVPLQRLATESEVSAAIVFLLTD
HHCCEEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHCCCHHHHHCHHHHHHEEEHHHHH
AAAFITGDVIKIDGGASCNTKIFPLEETTASKPYEGFHRASAPRILGGESKE
HHHHHCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]