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The map label for this gene is ydhC [C]

Identifier: 108762284

GI number: 108762284

Start: 2552830

End: 2554047

Strand: Reverse

Name: ydhC [C]

Synonym: MXAN_2212

Alternate gene names: 108762284

Gene position: 2554047-2552830 (Counterclockwise)

Preceding gene: 108760454

Following gene: 108763486

Centisome position: 27.94

GC content: 66.67

Gene sequence:

>1218_bases
ATGTCCCCCCGTCCGCCGTTCCTGCTCGCCATTCTGCTCCTGAGCTTTCCGCAGATCGTTGAAACCATCTACAGCCCAGC
CCTGCCGCTGATCGCTACGGCCTATCGCGTCACCCCAGCCGAAACGGGCCAGACGCTGTCACTCTGGTTCGCAGCCTTCG
CTTTCGGCGTGGTGGCCTGGGGCCGGCTCTCCGATCTGTGGGGCCGCCGCCCGGCGCTGCTTGCGGGCCTTGCGCTTTAT
GCGGCGGGTGCGGCTTGGGCCATGGTCGCCAGTGATTTCTCACATTTGCTGGCCGCACGGCTTATTTCCGCCTTCGGGGC
GGCGGTTGGATCGATCGTTACCCAGACCGCGCTACGCGATAGCCATGCTGGGCCGGAGCTGGGCCGGGTCTTCGCGGTGC
TTGGGCTGGCGCTGGCTATCAGCCCGGCGGTGGGCCTCTTCGCAGGCCAACTGCTCGCGGCCAAGGCCGGTCACAGTGGC
GTCTTCGCGGCCCTCGGCCTGCTTGCGGCGTTCATGCTCGGGTTGAGTCTCTGGCGCTGGCCTGAAACCCGCCCCGCTAC
TTTGTCTGTCGCCCCATTCTGGCCCACCTTCCGAGTCATGCTCCGCGATCCCGGCATTTGGCGCTGTACCCTGCTGATCG
CCGCATTCAATGCCGCGATCTTCGCCTGGTACCAGCTTGGCCCCTTCCTCTTTGCCGGGTTGGAGAACCCCTGGCTCTCA
TTCGGCCAGAGCGGTTTCCTGCTCGCCGCCGGTGCGCTGGCGGGGGCGCTGATGAACCGTGCCCTGTTGCGCCGCGGTTG
GACGGCGGAAGCGCTGATCGCGCTCGGCGTCCTCCTCCTGGGGGCGGGGACCGCGCTCGTCATCCTGCTCACCGCGCTTC
TGCCGCAGAGCCTGGCCTTCCTGAGCGGCGTGACGCTGATCTCGTCCGCATATGCCGTCGCGATCCCCAATGTGCTGGGC
ATCGCCCTGCGAGCCTATGCTGATCGGTTCGGAACTGCTGGCGCAGTCCTGAGTCTCTTCTACTACAACCTCCTCGGGGC
GGGACTGGTGATTGCCGGCTACGGGCAGCGCCTAGATTTTGCCTTGGCCGTCTGCGCGCTGCTGGCGGCGATCGTCAGCG
TCCGGCCAATGAGGTGCAGAGGAGCGTTGAGTGAGGAGTCGCCGCCGGGGGGCAAGTCCCGAATCCCGTGTAGTTCGTCA
GGAGGGGGTCGGAGCTGA

Upstream 100 bases:

>100_bases
CAGGGCACTTGTCCGATTTCCGATGGAAATTGTCTTTCCGTTTGTAATACGCGGAGGCCCGAACGGCTAGACGTGATGGC
GAATCGTCGTTGAGGTTGCC

Downstream 100 bases:

>100_bases
GGGCTCCCGTCATCTAGCAAGTGGATCAGCCAGCGCCTGCCTGGCCGCCACGTGCGAGGGAGCTGGCGCCTGGGCAGAAG
GACGGCCACCAGGAAGCGTA

Product: putative drug resistance transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MSPRPPFLLAILLLSFPQIVETIYSPALPLIATAYRVTPAETGQTLSLWFAAFAFGVVAWGRLSDLWGRRPALLAGLALY
AAGAAWAMVASDFSHLLAARLISAFGAAVGSIVTQTALRDSHAGPELGRVFAVLGLALAISPAVGLFAGQLLAAKAGHSG
VFAALGLLAAFMLGLSLWRWPETRPATLSVAPFWPTFRVMLRDPGIWRCTLLIAAFNAAIFAWYQLGPFLFAGLENPWLS
FGQSGFLLAAGALAGALMNRALLRRGWTAEALIALGVLLLGAGTALVILLTALLPQSLAFLSGVTLISSAYAVAIPNVLG
IALRAYADRFGTAGAVLSLFYYNLLGAGLVIAGYGQRLDFALAVCALLAAIVSVRPMRCRGALSEESPPGGKSRIPCSSS
GGGRS

Sequences:

>Translated_405_residues
MSPRPPFLLAILLLSFPQIVETIYSPALPLIATAYRVTPAETGQTLSLWFAAFAFGVVAWGRLSDLWGRRPALLAGLALY
AAGAAWAMVASDFSHLLAARLISAFGAAVGSIVTQTALRDSHAGPELGRVFAVLGLALAISPAVGLFAGQLLAAKAGHSG
VFAALGLLAAFMLGLSLWRWPETRPATLSVAPFWPTFRVMLRDPGIWRCTLLIAAFNAAIFAWYQLGPFLFAGLENPWLS
FGQSGFLLAAGALAGALMNRALLRRGWTAEALIALGVLLLGAGTALVILLTALLPQSLAFLSGVTLISSAYAVAIPNVLG
IALRAYADRFGTAGAVLSLFYYNLLGAGLVIAGYGQRLDFALAVCALLAAIVSVRPMRCRGALSEESPPGGKSRIPCSSS
GGGRS
>Mature_404_residues
SPRPPFLLAILLLSFPQIVETIYSPALPLIATAYRVTPAETGQTLSLWFAAFAFGVVAWGRLSDLWGRRPALLAGLALYA
AGAAWAMVASDFSHLLAARLISAFGAAVGSIVTQTALRDSHAGPELGRVFAVLGLALAISPAVGLFAGQLLAAKAGHSGV
FAALGLLAAFMLGLSLWRWPETRPATLSVAPFWPTFRVMLRDPGIWRCTLLIAAFNAAIFAWYQLGPFLFAGLENPWLSF
GQSGFLLAAGALAGALMNRALLRRGWTAEALIALGVLLLGAGTALVILLTALLPQSLAFLSGVTLISSAYAVAIPNVLGI
ALRAYADRFGTAGAVLSLFYYNLLGAGLVIAGYGQRLDFALAVCALLAAIVSVRPMRCRGALSEESPPGGKSRIPCSSSG
GGRS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=235, Percent_Identity=28.0851063829787, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788509, Length=136, Percent_Identity=30.8823529411765, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790146, Length=175, Percent_Identity=27.4285714285714, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42239; Mature: 42108

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPRPPFLLAILLLSFPQIVETIYSPALPLIATAYRVTPAETGQTLSLWFAAFAFGVVAW
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
GRLSDLWGRRPALLAGLALYAAGAAWAMVASDFSHLLAARLISAFGAAVGSIVTQTALRD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHAGPELGRVFAVLGLALAISPAVGLFAGQLLAAKAGHSGVFAALGLLAAFMLGLSLWRW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
PETRPATLSVAPFWPTFRVMLRDPGIWRCTLLIAAFNAAIFAWYQLGPFLFAGLENPWLS
CCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FGQSGFLLAAGALAGALMNRALLRRGWTAEALIALGVLLLGAGTALVILLTALLPQSLAF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVTLISSAYAVAIPNVLGIALRAYADRFGTAGAVLSLFYYNLLGAGLVIAGYGQRLDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEECCCCHHHH
ALAVCALLAAIVSVRPMRCRGALSEESPPGGKSRIPCSSSGGGRS
HHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPRPPFLLAILLLSFPQIVETIYSPALPLIATAYRVTPAETGQTLSLWFAAFAFGVVAW
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
GRLSDLWGRRPALLAGLALYAAGAAWAMVASDFSHLLAARLISAFGAAVGSIVTQTALRD
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHAGPELGRVFAVLGLALAISPAVGLFAGQLLAAKAGHSGVFAALGLLAAFMLGLSLWRW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
PETRPATLSVAPFWPTFRVMLRDPGIWRCTLLIAAFNAAIFAWYQLGPFLFAGLENPWLS
CCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
FGQSGFLLAAGALAGALMNRALLRRGWTAEALIALGVLLLGAGTALVILLTALLPQSLAF
CCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSGVTLISSAYAVAIPNVLGIALRAYADRFGTAGAVLSLFYYNLLGAGLVIAGYGQRLDF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEECCCCHHHH
ALAVCALLAAIVSVRPMRCRGALSEESPPGGKSRIPCSSSGGGRS
HHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA