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The map label for this gene is yafC [C]

Identifier: 108762266

GI number: 108762266

Start: 5361171

End: 5362052

Strand: Direct

Name: yafC [C]

Synonym: MXAN_4356

Alternate gene names: 108762266

Gene position: 5361171-5362052 (Clockwise)

Preceding gene: 108762829

Following gene: 108761738

Centisome position: 58.66

GC content: 68.93

Gene sequence:

>882_bases
ATGGACCTCAACGAGCTGCTCGTCTTCGCACGCGTCGTACAGGCAGGCAGCTTCACCGCCGCGGCGCGTGGGCTGCGGAT
GCCCAAGTCCACGGTGAGCCGGAAGGTGTCGGAGCTGGAGACGCGGGTCGGCGCGCAGTTGCTCCAGCGCACCACGCGCA
AGCTGCGCCTCACCGACGTGGGCCGGACGTACTACGAGCACTGCGCGCGCATCGTCGCGGAGGCGGAGCAGGCCGAACTG
GCCGTGACGCGGATGCAGGCCGCCCCCCATGGCCTGCTGCGTGTGACGACGCCGCTGACGTTCAGCTTCATCGGGCCACT
GGTGTCCACCTTCATCAAGCAGTACCCCGAGGTCCAGCTCGAGATGGTGTGTACCGACCGCAACGTGGACCTGGTGGCGG
AAGGCTTCGACTTGGCGATTCGCGCCGGGCGGCTGGCGGACTCGTCACTCATGGCGCGGCGGCTGGGCATCGTGGAGCGC
GTCGTCATCGCCGCGCCCAGCTATCTCAAGGCGCGCGGGACGCCCAAGGCTCCGAAGGATTTGGAGAAGCATGACTGCCT
CCTCTTCGGCGCGGGCCTGGAGAACAACGTCTGGACGCTCCACTCCGGCAACCGCTCGGTGGACATCAAGGTGCCCGCCC
GAATCGTCGTGAATGAGCCGGACATGCTCTACGCGGTGGCGCGGGCGGGCTCCGGCATCGCCCTGCTCCCCAACCTCCAC
TTCACCTCGGAGCTGGCCGCCGGGCGCTTGCAGCGCATCCTGCCGGACTGGAGCTCCACGGGCGCGCCCGTCCACGCCGT
CTACCCAAGCACGCGGCACCACTCCCCCAAGGTGATGGCCTTCGTGGAGTGCCTGCGCGAGCACTGGCCCATCCCCGGCT
GA

Upstream 100 bases:

>100_bases
CGACGAGGAGGAAGGTAGCGGTGTCCCCCGGGCTTGATTAGATGGGCCAGACTGGAAGAACTGTTCCACCCACGGAACAA
CGCTCCGGGAAGGACGGGAG

Downstream 100 bases:

>100_bases
ACGGGACATCGTTCCATCAACGGAACGATGCTTCCCATTGTCCACGCCTAGTCCCGAAAGGCCCTCGCGCACATCATGAC
TCTCGAAACAGCGGCCGCCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDLNELLVFARVVQAGSFTAAARGLRMPKSTVSRKVSELETRVGAQLLQRTTRKLRLTDVGRTYYEHCARIVAEAEQAEL
AVTRMQAAPHGLLRVTTPLTFSFIGPLVSTFIKQYPEVQLEMVCTDRNVDLVAEGFDLAIRAGRLADSSLMARRLGIVER
VVIAAPSYLKARGTPKAPKDLEKHDCLLFGAGLENNVWTLHSGNRSVDIKVPARIVVNEPDMLYAVARAGSGIALLPNLH
FTSELAAGRLQRILPDWSSTGAPVHAVYPSTRHHSPKVMAFVECLREHWPIPG

Sequences:

>Translated_293_residues
MDLNELLVFARVVQAGSFTAAARGLRMPKSTVSRKVSELETRVGAQLLQRTTRKLRLTDVGRTYYEHCARIVAEAEQAEL
AVTRMQAAPHGLLRVTTPLTFSFIGPLVSTFIKQYPEVQLEMVCTDRNVDLVAEGFDLAIRAGRLADSSLMARRLGIVER
VVIAAPSYLKARGTPKAPKDLEKHDCLLFGAGLENNVWTLHSGNRSVDIKVPARIVVNEPDMLYAVARAGSGIALLPNLH
FTSELAAGRLQRILPDWSSTGAPVHAVYPSTRHHSPKVMAFVECLREHWPIPG
>Mature_293_residues
MDLNELLVFARVVQAGSFTAAARGLRMPKSTVSRKVSELETRVGAQLLQRTTRKLRLTDVGRTYYEHCARIVAEAEQAEL
AVTRMQAAPHGLLRVTTPLTFSFIGPLVSTFIKQYPEVQLEMVCTDRNVDLVAEGFDLAIRAGRLADSSLMARRLGIVER
VVIAAPSYLKARGTPKAPKDLEKHDCLLFGAGLENNVWTLHSGNRSVDIKVPARIVVNEPDMLYAVARAGSGIALLPNLH
FTSELAAGRLQRILPDWSSTGAPVHAVYPSTRHHSPKVMAFVECLREHWPIPG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=288, Percent_Identity=36.8055555555556, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=35.2941176470588, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI145693193, Length=290, Percent_Identity=32.0689655172414, Blast_Score=147, Evalue=9e-37,
Organism=Escherichia coli, GI1789440, Length=285, Percent_Identity=29.8245614035088, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI87081978, Length=301, Percent_Identity=32.890365448505, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=26.6211604095563, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=27.4914089347079, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789173, Length=251, Percent_Identity=28.6852589641434, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI157672245, Length=116, Percent_Identity=32.7586206896552, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788706, Length=289, Percent_Identity=22.4913494809689, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790011, Length=257, Percent_Identity=22.9571984435798, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1786448, Length=281, Percent_Identity=25.9786476868327, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=146, Percent_Identity=31.5068493150685, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787601, Length=125, Percent_Identity=26.4, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082132, Length=298, Percent_Identity=24.1610738255034, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32265; Mature: 32265

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLNELLVFARVVQAGSFTAAARGLRMPKSTVSRKVSELETRVGAQLLQRTTRKLRLTDV
CCHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
GRTYYEHCARIVAEAEQAELAVTRMQAAPHGLLRVTTPLTFSFIGPLVSTFIKQYPEVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEE
EMVCTDRNVDLVAEGFDLAIRAGRLADSSLMARRLGIVERVVIAAPSYLKARGTPKAPKD
EEEEECCCCEEEECCCHHEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
LEKHDCLLFGAGLENNVWTLHSGNRSVDIKVPARIVVNEPDMLYAVARAGSGIALLPNLH
CCCCCEEEEECCCCCCEEEEECCCEEEEEEECEEEEECCCHHEEHEECCCCCEEEECCCC
FTSELAAGRLQRILPDWSSTGAPVHAVYPSTRHHSPKVMAFVECLREHWPIPG
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDLNELLVFARVVQAGSFTAAARGLRMPKSTVSRKVSELETRVGAQLLQRTTRKLRLTDV
CCHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHH
GRTYYEHCARIVAEAEQAELAVTRMQAAPHGLLRVTTPLTFSFIGPLVSTFIKQYPEVQL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCEEE
EMVCTDRNVDLVAEGFDLAIRAGRLADSSLMARRLGIVERVVIAAPSYLKARGTPKAPKD
EEEEECCCCEEEECCCHHEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCC
LEKHDCLLFGAGLENNVWTLHSGNRSVDIKVPARIVVNEPDMLYAVARAGSGIALLPNLH
CCCCCEEEEECCCCCCEEEEECCCEEEEEEECEEEEECCCHHEEHEECCCCCEEEECCCC
FTSELAAGRLQRILPDWSSTGAPVHAVYPSTRHHSPKVMAFVECLREHWPIPG
HHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]