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The map label for this gene is prmA

Identifier: 108762169

GI number: 108762169

Start: 1326300

End: 1327166

Strand: Reverse

Name: prmA

Synonym: MXAN_1139

Alternate gene names: 108762169

Gene position: 1327166-1326300 (Counterclockwise)

Preceding gene: 108759240

Following gene: 108763160

Centisome position: 14.52

GC content: 68.4

Gene sequence:

>867_bases
ATGTCCCAGACCTATCTGTCACTCACAGTGGAGTTGCCCGAGGAAGCGTCCGAGGCCGTACAGGACCTCCTCCACGAGTC
GGGCGCGCTGGGCCTCGAAGTGCGGGACCGCGAAGCGCCCCTCATGCCGGGCGTGCGCGGACCGAACCCTGGCGAGGCCA
TCATCATCGGCTACTTCGACGAGCGCGACACGGCCGAGTCCGCCCGTGACGAGGTGGCGTCGTCCTTCCCCGAGGCGAAG
CTCACATTGGATGAGCAGCCCCAGCAGGACTGGAGCAACGAGTGGAAGTCGCTCATCAAGTCCGTGCATGTGGGCAGGTT
GTGGGTCGGTCCTCCGTGGGACAAGGCGAACGCGCCCGCGGGCACCGTGCAGCTCGTGATTGAGCCGAAGATGGCCTTTG
GCACCGGCGACCACCCGACGACGTCCCTGTGCCTGGCCGCGGTGGACGCATACATGGCCGAGCACCCGGGCGCCGCCGTC
CTGGACGTAGGCACCGGCACGGGCGTGCTGGCCATCGCCGCGAAGAAGCTGGGCGCGGGCCGCACCGTGGCCACCGACAA
CGACCCCATCTCCGTGGAGCTGGCGCAGGAGAACCAAGCGGAGAACGGCACGCCGGACATCGAGGTCTCCGGCAAGGAGC
TGACCCAGGTGGAGGGCACCTTCGACCTGGTGCTCGCCAACATCCTGGCCAACACGCTCATCGAGCTGGCCCCGCTGATT
GTGGCGAAGACCAAGGACCGGCTCGTGCTGGCGGGTGTGCTCTCCCACCAGCGCGCGGACGTGGAAGCCGCCTACCGCAA
CCTGGGCCTCACCGTGCTGACCGGCGCCACCCAGGGCGAATGGGTGCGCATCGACCTGCAGCGCTGA

Upstream 100 bases:

>100_bases
GTCCGGACCCGAGCAGGCAGTCAGGCAGATCAGGGGCCACCAGCGAATGAGGCGTCTCACGGCGCTTCCACGCTAGCCAC
GCTGGGATTAAAGGGCCCGC

Downstream 100 bases:

>100_bases
AGTACATGGCGCCGTCCCCGTGAGGCATGTGCGGGGACGGCGGCCCTGGGGTGCCAGGCATCGCTCGCGGGCGCCGGCCC
TGACACCGGCCTCACCTCCC

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 288; Mature: 287

Protein sequence:

>288_residues
MSQTYLSLTVELPEEASEAVQDLLHESGALGLEVRDREAPLMPGVRGPNPGEAIIIGYFDERDTAESARDEVASSFPEAK
LTLDEQPQQDWSNEWKSLIKSVHVGRLWVGPPWDKANAPAGTVQLVIEPKMAFGTGDHPTTSLCLAAVDAYMAEHPGAAV
LDVGTGTGVLAIAAKKLGAGRTVATDNDPISVELAQENQAENGTPDIEVSGKELTQVEGTFDLVLANILANTLIELAPLI
VAKTKDRLVLAGVLSHQRADVEAAYRNLGLTVLTGATQGEWVRIDLQR

Sequences:

>Translated_288_residues
MSQTYLSLTVELPEEASEAVQDLLHESGALGLEVRDREAPLMPGVRGPNPGEAIIIGYFDERDTAESARDEVASSFPEAK
LTLDEQPQQDWSNEWKSLIKSVHVGRLWVGPPWDKANAPAGTVQLVIEPKMAFGTGDHPTTSLCLAAVDAYMAEHPGAAV
LDVGTGTGVLAIAAKKLGAGRTVATDNDPISVELAQENQAENGTPDIEVSGKELTQVEGTFDLVLANILANTLIELAPLI
VAKTKDRLVLAGVLSHQRADVEAAYRNLGLTVLTGATQGEWVRIDLQR
>Mature_287_residues
SQTYLSLTVELPEEASEAVQDLLHESGALGLEVRDREAPLMPGVRGPNPGEAIIIGYFDERDTAESARDEVASSFPEAKL
TLDEQPQQDWSNEWKSLIKSVHVGRLWVGPPWDKANAPAGTVQLVIEPKMAFGTGDHPTTSLCLAAVDAYMAEHPGAAVL
DVGTGTGVLAIAAKKLGAGRTVATDNDPISVELAQENQAENGTPDIEVSGKELTQVEGTFDLVLANILANTLIELAPLIV
AKTKDRLVLAGVLSHQRADVEAAYRNLGLTVLTGATQGEWVRIDLQR

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=248, Percent_Identity=33.4677419354839, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_MYXXD (Q1DD74)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629399.1
- ProteinModelPortal:   Q1DD74
- SMR:   Q1DD74
- STRING:   Q1DD74
- GeneID:   4105915
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1139
- TIGR:   MXAN_1139
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   IPEWEIY
- PhylomeDB:   Q1DD74
- ProtClustDB:   CLSK944921
- BioCyc:   MXAN246197:MXAN_1139-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 30747; Mature: 30616

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQTYLSLTVELPEEASEAVQDLLHESGALGLEVRDREAPLMPGVRGPNPGEAIIIGYFD
CCCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEC
ERDTAESARDEVASSFPEAKLTLDEQPQQDWSNEWKSLIKSVHVGRLWVGPPWDKANAPA
CCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
GTVQLVIEPKMAFGTGDHPTTSLCLAAVDAYMAEHPGAAVLDVGTGTGVLAIAAKKLGAG
CEEEEEEECCEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEHHHCCCC
RTVATDNDPISVELAQENQAENGTPDIEVSGKELTQVEGTFDLVLANILANTLIELAPLI
CEEECCCCCEEEEEECCCCCCCCCCCEEECCCHHEECCCHHHHHHHHHHHHHHHHHHHHH
VAKTKDRLVLAGVLSHQRADVEAAYRNLGLTVLTGATQGEWVRIDLQR
EECCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECC
>Mature Secondary Structure 
SQTYLSLTVELPEEASEAVQDLLHESGALGLEVRDREAPLMPGVRGPNPGEAIIIGYFD
CCEEEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEEC
ERDTAESARDEVASSFPEAKLTLDEQPQQDWSNEWKSLIKSVHVGRLWVGPPWDKANAPA
CCCHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
GTVQLVIEPKMAFGTGDHPTTSLCLAAVDAYMAEHPGAAVLDVGTGTGVLAIAAKKLGAG
CEEEEEEECCEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEHHHCCCC
RTVATDNDPISVELAQENQAENGTPDIEVSGKELTQVEGTFDLVLANILANTLIELAPLI
CEEECCCCCEEEEEECCCCCCCCCCCEEECCCHHEECCCHHHHHHHHHHHHHHHHHHHHH
VAKTKDRLVLAGVLSHQRADVEAAYRNLGLTVLTGATQGEWVRIDLQR
EECCCCCEEEEHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA