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The map label for this gene is dapE [H]

Identifier: 108762096

GI number: 108762096

Start: 2659715

End: 2661181

Strand: Direct

Name: dapE [H]

Synonym: MXAN_2289

Alternate gene names: 108762096

Gene position: 2659715-2661181 (Clockwise)

Preceding gene: 108758552

Following gene: 108761528

Centisome position: 29.1

GC content: 70.96

Gene sequence:

>1467_bases
TTGCCGATGAAACGCATCCTCTTGTCGTTGTTGTTTGTCGTCGTTGCCCTCGCGGGGGTTCTCCTCACGAAGGCTTTTCG
CTTCACCTCTCGGCAGGTCCAGCCGGAGGCGCCCGCGGAGTTCACCGTGGACGCGGATGCCGCCGCGGCCCGGCTGGGCG
GTGCGCTGCGGCTCAAGACGCTGGCGGCGGCGGAGGGGCAGGCTGCGGAGGACGCCGCCTTCACCGCGCTCCACGACTAC
ATGCGGGAGCAATACCCCCGGCTTCATCAGGCGCTGAAGCGCGAGCCCGTGGGGGCGCACTCGGTGCTGTACACCTGGAC
GGGGACGGACGCGTCGCTGCGCCCGGCGCTGCTGCTGGGGCACCTGGACGTGGTGCCCGTGGAGCCCGGCACGGAGGCGT
CCTGGACTCACCCGCCCTATAGCGGGCTGGTGGCGGACGGCTATGTCTGGGGCCGGGGCGCGCTGGACGACAAGGGGAGC
GTGTTCGGCATCCTGGAGTCGGTGGAGGCGCTGCTCGCGGCGGGCTTCCAGCCCAAGCGCACGGTGCTGCTCGCCTTCGG
TGGGGATGAAGAGGTGGGTGGGCGCGAGGGCGCGGAGGCGATGGCGAAGCTGCTCCGCGAGCGGGGCGTGACGCTGGAAT
CCGTGCTGGACGAGGGCGGGATGATTGTGTCCGGCACCGTGCCCGGCGTGGCCTCACCGGTGGCCCTGGTCGGCGTGTCG
GAGAAGGGCTTCGCCAGCGCGGAGTTGGTGGCGGATGGCGAAGGCGGCCATTCGTCCATGCCGCCGCCCCAGACGGCCGT
GGGCGTGCTGAGCCGCGCCATCTCCCGGCTGGAGGATGCGCCCATGCCCGCGAAGCTGCGCGGTGGCAGCCGGGCCCTGT
TCGAGTTCGCGGGGCCGGAGATGGGCTTCGGGATGCGCACGCTCTTCGCCAACCTGTGGCTGTTCGAGCCGCTGGTGCTG
CGCCAGCTCACCGCGAAGGCCACCACCAACGCGGCGGTGCGCACCACCACCGCGGCCACCATGTTCGAGGGCAGCGAGCG
CGACAACGTGCTGCCCGCCCGCGCCCGCGCGGTGGTGAACTTCCGCATCCTCCCCGGAGACTCCGTGGCGGGCGTGCTGG
AGCACGTGCGGCGCGTGGTGGATGACCCGCGGGTGAAGGTGCGCACGCTGGGCTTCATCAGTGAACCGTCGCCCGTGTCG
CGCATGGACTCCGAGGCGTGGTCGCAGCTCCAGCGCAGCGTGCGCCAGGTGTTCCCCGACGTCGTCGTGGCCCCGTACCT
CATGCTGGGCGCGACGGATTCGCGCTACTTCACCGGGCTGAGTGAGAACGTCTACCGCTTCATGCCGCTGCGCCTGGACG
GCGCCGACCTGTCACGCCTCCACGGCAAGGACGAGCGCGTGTCGGTGAAGGGCTACGCGGACGCGGTGCGCTTCTATGCC
CAATACGTCCGCAACGTGGCCCAGTGA

Upstream 100 bases:

>100_bases
GTGGTTCGTGGAAGCGAGGCCTGCCGTGGAGGCTCTGCCCTGGAGACGCAGTGGGGTGGCGGGCCGCCTTTGCTAGCGTG
AGGCGTCCCCACCGCGAGTC

Downstream 100 bases:

>100_bases
CGCCGGTGGGAACGGGGGGAATGGCCCGCACGGGACGTGTGCGCCCCGTGCTTCACGCCGCTTCCGACTTTCTACGAAAG
TGATGTTTCAGGCGTTGTTG

Product: hypothetical protein

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MPMKRILLSLLFVVVALAGVLLTKAFRFTSRQVQPEAPAEFTVDADAAAARLGGALRLKTLAAAEGQAAEDAAFTALHDY
MREQYPRLHQALKREPVGAHSVLYTWTGTDASLRPALLLGHLDVVPVEPGTEASWTHPPYSGLVADGYVWGRGALDDKGS
VFGILESVEALLAAGFQPKRTVLLAFGGDEEVGGREGAEAMAKLLRERGVTLESVLDEGGMIVSGTVPGVASPVALVGVS
EKGFASAELVADGEGGHSSMPPPQTAVGVLSRAISRLEDAPMPAKLRGGSRALFEFAGPEMGFGMRTLFANLWLFEPLVL
RQLTAKATTNAAVRTTTAATMFEGSERDNVLPARARAVVNFRILPGDSVAGVLEHVRRVVDDPRVKVRTLGFISEPSPVS
RMDSEAWSQLQRSVRQVFPDVVVAPYLMLGATDSRYFTGLSENVYRFMPLRLDGADLSRLHGKDERVSVKGYADAVRFYA
QYVRNVAQ

Sequences:

>Translated_488_residues
MPMKRILLSLLFVVVALAGVLLTKAFRFTSRQVQPEAPAEFTVDADAAAARLGGALRLKTLAAAEGQAAEDAAFTALHDY
MREQYPRLHQALKREPVGAHSVLYTWTGTDASLRPALLLGHLDVVPVEPGTEASWTHPPYSGLVADGYVWGRGALDDKGS
VFGILESVEALLAAGFQPKRTVLLAFGGDEEVGGREGAEAMAKLLRERGVTLESVLDEGGMIVSGTVPGVASPVALVGVS
EKGFASAELVADGEGGHSSMPPPQTAVGVLSRAISRLEDAPMPAKLRGGSRALFEFAGPEMGFGMRTLFANLWLFEPLVL
RQLTAKATTNAAVRTTTAATMFEGSERDNVLPARARAVVNFRILPGDSVAGVLEHVRRVVDDPRVKVRTLGFISEPSPVS
RMDSEAWSQLQRSVRQVFPDVVVAPYLMLGATDSRYFTGLSENVYRFMPLRLDGADLSRLHGKDERVSVKGYADAVRFYA
QYVRNVAQ
>Mature_487_residues
PMKRILLSLLFVVVALAGVLLTKAFRFTSRQVQPEAPAEFTVDADAAAARLGGALRLKTLAAAEGQAAEDAAFTALHDYM
REQYPRLHQALKREPVGAHSVLYTWTGTDASLRPALLLGHLDVVPVEPGTEASWTHPPYSGLVADGYVWGRGALDDKGSV
FGILESVEALLAAGFQPKRTVLLAFGGDEEVGGREGAEAMAKLLRERGVTLESVLDEGGMIVSGTVPGVASPVALVGVSE
KGFASAELVADGEGGHSSMPPPQTAVGVLSRAISRLEDAPMPAKLRGGSRALFEFAGPEMGFGMRTLFANLWLFEPLVLR
QLTAKATTNAAVRTTTAATMFEGSERDNVLPARARAVVNFRILPGDSVAGVLEHVRRVVDDPRVKVRTLGFISEPSPVSR
MDSEAWSQLQRSVRQVFPDVVVAPYLMLGATDSRYFTGLSENVYRFMPLRLDGADLSRLHGKDERVSVKGYADAVRFYAQ
YVRNVAQ

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Homo sapiens, GI269846968, Length=456, Percent_Identity=38.8157894736842, Blast_Score=317, Evalue=2e-86,
Organism=Homo sapiens, GI4501901, Length=384, Percent_Identity=25.2604166666667, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538640, Length=398, Percent_Identity=25.8793969849246, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71982710, Length=397, Percent_Identity=24.6851385390428, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322289, Length=524, Percent_Identity=30.5343511450382, Blast_Score=234, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24649206, Length=427, Percent_Identity=23.8875878220141, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24649210, Length=430, Percent_Identity=23.953488372093, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24649208, Length=403, Percent_Identity=24.317617866005, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24649212, Length=426, Percent_Identity=23.2394366197183, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24649202, Length=433, Percent_Identity=23.094688221709, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24649204, Length=433, Percent_Identity=23.094688221709, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356353, Length=414, Percent_Identity=23.6714975845411, Blast_Score=82, Evalue=9e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 52473; Mature: 52342

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKRILLSLLFVVVALAGVLLTKAFRFTSRQVQPEAPAEFTVDADAAAARLGGALRLKT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHCCHHHHHH
LAAAEGQAAEDAAFTALHDYMREQYPRLHQALKREPVGAHSVLYTWTGTDASLRPALLLG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHCC
HLDVVPVEPGTEASWTHPPYSGLVADGYVWGRGALDDKGSVFGILESVEALLAAGFQPKR
CCEEEECCCCCCCCCCCCCCCCEEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TVLLAFGGDEEVGGREGAEAMAKLLRERGVTLESVLDEGGMIVSGTVPGVASPVALVGVS
EEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCCCCCEEEEECC
EKGFASAELVADGEGGHSSMPPPQTAVGVLSRAISRLEDAPMPAKLRGGSRALFEFAGPE
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCC
MGFGMRTLFANLWLFEPLVLRQLTAKATTNAAVRTTTAATMFEGSERDNVLPARARAVVN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCHHHHEEEEE
FRILPGDSVAGVLEHVRRVVDDPRVKVRTLGFISEPSPVSRMDSEAWSQLQRSVRQVFPD
EEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHH
VVVAPYLMLGATDSRYFTGLSENVYRFMPLRLDGADLSRLHGKDERVSVKGYADAVRFYA
HHHHHHHHHCCCCCHHHCCCCCCHHEEEEEEECCCCHHHHCCCCCEEEEHHHHHHHHHHH
QYVRNVAQ
HHHHHHCC
>Mature Secondary Structure 
PMKRILLSLLFVVVALAGVLLTKAFRFTSRQVQPEAPAEFTVDADAAAARLGGALRLKT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHCCHHHHHH
LAAAEGQAAEDAAFTALHDYMREQYPRLHQALKREPVGAHSVLYTWTGTDASLRPALLLG
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHCC
HLDVVPVEPGTEASWTHPPYSGLVADGYVWGRGALDDKGSVFGILESVEALLAAGFQPKR
CCEEEECCCCCCCCCCCCCCCCEEECCEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
TVLLAFGGDEEVGGREGAEAMAKLLRERGVTLESVLDEGGMIVSGTVPGVASPVALVGVS
EEEEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHCCCCEEEECCCCCCCCCEEEEECC
EKGFASAELVADGEGGHSSMPPPQTAVGVLSRAISRLEDAPMPAKLRGGSRALFEFAGPE
CCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHCCCC
MGFGMRTLFANLWLFEPLVLRQLTAKATTNAAVRTTTAATMFEGSERDNVLPARARAVVN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCCCCCCCCCCHHHHEEEEE
FRILPGDSVAGVLEHVRRVVDDPRVKVRTLGFISEPSPVSRMDSEAWSQLQRSVRQVFPD
EEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHH
VVVAPYLMLGATDSRYFTGLSENVYRFMPLRLDGADLSRLHGKDERVSVKGYADAVRFYA
HHHHHHHHHCCCCCHHHCCCCCCHHEEEEEEECCCCHHHHCCCCCEEEEHHHHHHHHHHH
QYVRNVAQ
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA